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Topic: 1,4-Butanediol

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Production of 1,4-butanediol - Patent 4172961 The flow of the two streams is countercurrent through the extraction zone wherein they are brought into intimate contact to effect the desired extraction of impurities from the aqueous 1,4-butanediol-containing mixture. Butanediol has been manufactured commercially by processes involving the Reppe reaction of acetylene and formaldehyde followed by hydrogenation of the reaction mixture. Stoichiometrically, five moles of hydrogen are required for each mole of dialkyl alkoxy succinate converted to butanediol. www.freepatentsonline.com /4172961.html   (6350 words)

News from DEA, News Releases, 10/28/03 1,4- butanediol is a chemical intermediate generally classified as a captive use product; that is, it is not intended for residential consumers, but is used in the manufacture of other products. More than 2000 gallons of 1,4- butanediol and $300,000 cash were seized at the time of their arrest. Their internet site advertised 1,4 butanediol as a cleaning product with various uses including spot remover, paint stripper and as a cleaning agent for computer circuit boards, grating and brickwork and tile. www.usdoj.gov /dea/pubs/pressrel/pr102803.html   (600 words)

Conversion of contaminated polyethylene terephthalate to decontaminated polybutylene terephthalate - US Patent 6518322 The liquid mass was then polymerised by removing ethanediol and butanediol under 0.01 to 0.1 bar at a temperature between 230 to 250° C. to give decontaminated PBT in 60 minutes. The vapour was condensed and the ethanediol recovered. The mixture was then filtered in a hot pressure filter to remove the loaded adsorbents and the liquid mass transferred back to a 250 ml flask. www.patentstorm.us /patents/6518322.html   (2889 words)

1,4-Butanediol, Borametz Oil, Can You Give Me Some Insight Into Promusol? The National Toxicology Program did a study of the toxicology of 1,4 Butanediol and found that since it was rapidly converted into GHB in the body the results would be the same as GHB-- no toxicity. Does anyone know for sure that the active ingredient in Promusol is 1,4 Butanediol, or is this discussion simply based on the assumption that the author of Answer 1 is correct in the statement that the active ingredient in Promusol is 1,4 Butanediol? Tests have found that it is really a chemical called 1,4 butanediol. www.nutritionalsupplements.com /borametz.html   (2710 words)

News and Issues - Media Releases: Ministry repeats Warning on GHB and 1,4 butanediol 1,4 butanediol, GHB, GBL and similar substances will be some of the first substances considered by this new committee that has been set up to streamline the process of legislating for substances that may be subject to abuse. 1,4 butanediol (One4b), GBL, GHB and sodium oxybate all have similar effects when consumed, with 1,4B, GBL and sodium oxybate breaking down to GHB in the body. The Ministry of Health is repeating its warning to the public not to consume any products containing 1,4 butanediol (One4b) or gamma hydroxy butyrate (GHB, GBH or Fantasy). www.moh.govt.nz /moh.nsf/30ad137c772c883e4c25665c002c4198/5b7c926adeceb27ccc256a3e006bb74c?OpenDocument   (973 words)

American College of Medical Toxicology Snead OC, Furner R, Liu C. In vivo conversion of gamma-aminobutyric acid and 1,4 butanediol to gamma-hydroxybutyric acid in rat brain. Poldrugo F, Snead O. 1,4 Butanediol, gamma-hydroxybutyric acid and ethanol: relationships and interactions. Butanediol (pine needle oil) is a commonly used industrial chemical that can be easily purchased by the public. www.ijmt.net /ijmt/4_1/4_1_12.html   (308 words)

FDA and the U.S. Attorney for the Western District of Texas Announce Guilty Plea in Drug Counterfeiting Case Ghandour told a newspaper reporter and an FDA Office of Criminal Investigations (OCI) agent that he did not use 1,4 butanediol in his products because he knew it was dangerous when consumed with alcohol, and he knew people were abusing his products. In May 1999, FDA issued a public warning about products containing 1,4 butanediol and declared the products to be a Class I Health Hazard. In April 1999, a man in Austin, Texas died as a result of consuming 1,4 butanediol. www.fda.gov /bbs/topics/news/2004/NEW01036.html   (1103 words)

GHB Analogs The analog status of GBL and 1,4 butanediol in each state needs to be clarified and adequate training given to law enforcement and prosecutorial agencies statewide. Mere possession of the precursor/analog GBL or the analog 1,4 butanediol is not illegal in and of itself at this time. Several of the products list the primary ingredient as 1,4 butanediol (BD) or its other chemical names, tetramethylene glycol or sucol-B. These products may also surface labeled as degreasing or cleaning products that are in reality being used for human consumption. www.projectghb.org /analogs.htm   (1584 words)

GHB Other products such as GBL and 1,4 butanediol (BD) are appearing in the illegal market as GHB substitutes. GHB can be made from ingredients such as GBL (gamma-butyrolactone), a solvent commonly used as a paint stripper, or butanediol (1,4-butanediol), a chemical used in the production of plastics and adhesives. GHB, GBL, and butanediol (BD) are difficult to trace because they quickly leave the body and may be difficult to detect in emergency rooms and other treatment facilities. www.streetdrugs.org /ghb.htm   (309 words)

NTP: Abstract for TOX-54 - 1,4-Butanediol Synonyms: Butanediol, butane-1,4-diol, 1,4-butylene glycol, 1,4-dihydroxybutane, 1,4-tetramethylene glycol, butylene glycol, tetramethylene 1,4-diol For these reasons, it is the opinion of the NTP that 1,4-butanediol should be considered not carcinogenic in animals and no further evaluation of 1,4-butanediol is needed at this time. You may link to the full toxicity report in pdf format (Note: A print ready copy of the document is presented in Portable Document Format (pdf) which requires the Acrobat Reader plug-in -- download a free copy of the reader. ntp.niehs.nih.gov /index.cfm?objectid=072D948C-CD0E-A8AF-C65F9A912520D893   (540 words)

Erowid 1,4-butanediol Vault Summary Report on Metabolism & Toxicity of 1,4-butanediol - Irwin, 1996 Is 99.8 \% pure butanediol suitable for consumption? Can you tell me about any deaths from research chemicals? www.erowid.org /chemicals/14b/14b.shtml   (150 words)

DEA Resources, Microgram Journal, Volume 1, January-June 2003 When the sample was run in D2O, chemical shift increases of 0.2 ppm were observed for all peaks, i.e., singlets were found at 1.6, 3.6, and 4.8 ppm, respectively (Figure 7). The proton spectra in CDCl3 showed singlet peaks at 1.4 (C2/C3 methylenes), 3.4 (C1/C4 methylenes), and 4.7 (hydroxyl protons) ppm (Figure 6). www.dea.gov /programs/forensicsci/microgram/journal_v1/mjournal_v1_pg7.html   (2064 words)

28626.020411&ELEMENT_SET=DECL Preferred divinyl ethers are 1,4-butanediol divinyl ether, 1,5-hexanediol divinyl ether and 1,4- cyclohexandimethanol divinyl ether. The most preferred AAPEs are linear, branched or ~chain extended copolyesters comprising about 50 to about 60 mole percent adipic acid, about 40 to about 50 mole percent terephthalic acid, and at least 95 mole percent 1,4- butanediol. 1,4- butanediol; a poly (ethylene succinate-co-terephthalate) containing 70% succinic www.wipo.int /cgi-pct/guest/getbykey5?KEY=02/28626.020411&ELEMENT_SET=DECL   (4053 words)

1,4-Butanediol Dimethanesulphonate (Myleran) (Suppl7) No mammary rumour was seen in rats after intraperitoneal injection, but near-lethal doses were used and the animals were followed for only five months [ref: 14]. Intravenous administration of Myleran to mice significantly increased the incidences of thymic and ovarian tumours [ref: 1]. Leukaemia/lymphosarcoma was also reported in one study [ref: 12], but the experiment could not be evaluated due to incomplete reporting. monographs.iarc.fr /htdocs/monographs/suppl7/myleran.html   (617 words)

Butanediol or "BD" Lawsuit Overview - Find Trial Lawyers and Attorneys with Experience in Butanediol or "BD" Personal Injury Law Butanediol or "BD" Lawsuit Overview - Find Trial Lawyers and Attorneys with Experience in Butanediol or "BD" Personal Injury Law www.injuryboard.com /view.cfm/Topic=913   (421 words)

News Release: Austin Man's Death Prompts TDH Warning about New Round of Bodybuilding Products Health authorities believe manufacturers are renaming their products and substituting 1,4 butanediol for GBL in this latest round of products. Other 1,4 butanediol product brand names included in the TDH warning are Revitalize Plus, Serenity, Enliven, GHRE, SomatoPro, NRG3 and Weight Belt Cleaner. Health officials say some of the suspect products may list 1,4 butanediol, tetramethylene glycol, gamma butyrolactone or 2(3H)-Furanone di-hydro on the label while others contain no label of any kind. www.tdh.state.tx.us /news/b_new274.htm   (460 words)

CNN Transcript - Early Edition: Study Suggests Dietary Supplements Containing 1,4-Butanediol Could Be Deadly - January 11, 2001 Dietary products with 1,4- Butanediol claim to aid in muscle building, improve athletic performance, improve libido or sexual performance and sleep enhancement. FIRFER: Hadi Ghandour's company GenaPharm manufactured and sold one of the products cited as dangerous in the most recent study; a product called "Thunder Nectar." He doesn't sell anything with 1,4- Butanediol anymore, but he claims the product was safe if used properly and would like to see it back on the market. FIRFER: Doctors say 1,4 Butanediol can induce vomiting, incontinence, dizziness, agitation, combativeness, seizures and coma. transcripts.cnn.com /TRANSCRIPTS/0101/11/ee.12.html   (1099 words)

Chemie.DE News-Center: BASF PETRONAS Chemicals utilizes new 1,4-butanediol plant below capacity As the global market leader in butanediol, BASF provides a reliable supply via its worldwide network of BDO plants in Europe, NAFTA and Asia. This is very important to us since we have a commitment to the butanediol markets." Customers will not be affected by this temporary below-capacity utilization. www.chemie.de /news/e/35783   (209 words)

Safety (MSDS) data for 1,4-butanediol This information was last updated on October 14, 2003. We have tried to make it as accurate and useful as possible, but can take no responsibility for its use, misuse, or accuracy. physchem.ox.ac.uk /MSDS/BU/1,4-butanediol.html   (86 words)

FDA/CFSAN Products that Consumers Inquire About Gamma Hydroxybutyric Acid (GHB), Gamma Butyrolactone (GBL), and 1,4 Butanediol (BD) FDA Issues Alert about Misuse of Consumer Products Containing Gamma Hydroxybutyric Acid (GHB), Gamma Butyrolactone (GBL), and 1,4 Butanediol (BD) (June 15, 1999) (Letter (PDF), Poster) (see also January 21, 1999 Talk Paper) A list of selected dietary supplements associated with serious safety problems appeared in an out-of-print 1993 FDA document "Unsubstantiated Claims and Documented Health Hazards in the Dietary Supplement Marketplace." The list is found in the document section entitled "Illnesses and Injuries Associated With the Use of Selected Dietary Supplements." vm.cfsan.fda.gov /~dms/ds-prod.html   (866 words)

050900c.txt Safety of Petitioned Use of the Additive The petitioner determined the levels of three migrants extracted from the additive, polyurethane resins manufactured from MDI, 1,4- butanediol, and adipic acid. That is, where an additive itself has not been shown to cause cancer, but contains a carcinogenic impurity, the additive is properly evaluated under the general safety standard using risk assessment procedures to determine whether there is a reasonable certainty that no harm will result from the intended use of the additive (Scott v. www.fda.gov /OHRMS/DOCKETS/98fr/050900c.txt   (1757 words)

Fantasy drugs GHB and 1,4-Butanediol to be classified The Expert Advisory Committee on Drugs has agreed that the 'Fantasy' range of drugs, including Gamma hydroxy butyrate (GHB), 1,4 butanediol, (1,4-B) and GBL should be scheduled under the Misuse of Drugs Act 1975. Fantasy drugs GHB and 1,4-Butanediol to be classified Committee chair, Dr Bob Boyd said that after considering the available evidence the committee had agreed that scheduling the substances under the Act would help protect individuals and the community from the harm associated with these drugs. www.moh.govt.nz /moh.nsf/f872666357c511eb4c25666d000c8888/44079a2baf27c069cc256a8e0014993d?OpenDocument   (734 words)

Apr 4, 2001 When administered intraperitoneally, one study reported that 1,4- butanediol dimethanesulfonate induced T-cell lymphomas in male mice; two other studies reported that it did not increase the incidence of tumors. When administered by intravenous injection, 1,4-butanediol dimethanesulfonate increased the incidence of thymic lymphomas and ovarian tumors in female mice (IARC V.4, 1974; IARC S.4, 1982; IARC S.7, 1987). www.maydaymystery.org /mayday/texts/01-apr4.html   (2074 words)

Butanediol Diglycidyl Ether - Araldite RD-2 - SPI Supplies Butanediol Diglycidyl Ether - Araldite RD-2 - SPI Supplies www.2spi.com /catalog/chem/labels/but.shtml   (62 words)

CCCBDB listing of experimental data 1,4-BD; 1,4-Butanediol; 1,4-Butylene glycol; 1,4-Dihydroxybutane; 1,4-Tetramethylene glycol; Butane-1,4-diol; Butanediol; Diol 14B; Sucol B; Tetramethylene 1,4-diol; Tetramethylene glycol; srdata.nist.gov /cccbdb/exp2.asp?casno=110634   (79 words)

1-4-Butanediol-99 - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - - CAS #: 110-63-4 MF: C4H10O2 EC NO: 203-786-5 SYNONYMS AGRISYNTH B1D * BUTANEDIOL * BUTANE-1,4-DIOL * 1,4-BUTYLENE GLYCOL * 1,4-DIHYDROXYBUTANE * DIOL 14B * SUCOL B * TETRAMETHYLENE 1,4-DIOL * 1,4-TETRAMETHYLENE GLYCOL * SECTION 3. www.conncoll.edu /offices/envhealth/MSDS/chemistry/B/1-4-Butanediol-99.html   (819 words)

ChemFinder.Com 1,4-Dihydroxybutane; 1,4-Butanediol; 1,4-Butylene glycol; 1,4-Tetramethylene; 1,4-tetramethylene glycol; diol 14b; butane-1,4-diol; butanediol; butylene glycol; sucol b; tetramethylene-1,4-diol; Tetramethylene glycol; chemfinder.cambridgesoft.com /result.asp?mol_rel_id=110-63-4   (146 words)

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