| | NTP: Abstract for TR-38 - Aroclor 1254 |
 | | Aroclor® 1254, a biphenyl containing approximately 54% chlorine, is a nonflammable heat transfer agent which functions in the range of 250-360 degrees C. A bioassay of Aroclor® 1254 for possible carcinogenicity was conducted by administering the test chemical in feed to Fischer 344 rats. |
 | | Groups of 24 rats of each sex were administered Aroclor® 1254 at one of three doses, either 25, 50, or 100 ppm, for 104-105 weeks. |
 | | It is concluded that under the conditions of this bioassay, Aroclor® 1254 was not carcinogenic in Fischer 344 rats; however, a high incidence of hepatocellular proliferative lesions in both male and female rats was related to administration of the chemical. |
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