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Novel Extranuclear-targeted Anthracyclines Override the Antiapoptotic Functions of Bcl-2 and Target Protein Kinase C ... AD 198 cytotoxicity is unaffected by Bcl-2 expression in 32D.3 myeloid cells. AD 198 and AD 445 cytotoxicities are unaffected by Bcl-2 expression in MCF-7 cells. The rapid induction of apoptosis by AD 198 in the mct.aacrjournals.org /cgi/content/full/1/7/469   (7266 words)

Ancient Greek Coinage Caracalla, 198-217 AD -- Thrace, Pautalia, Æ 30mm, 15.6 gr. Elagabalus, 218-222 AD -- Moesia Inferior, Nicopolis, Æ 27mm, 11.35 gr. Elagabalus, 218-222 AD -- Moesia Inferior, Marcianopolis, Æ 25mm, 10.4 gr. www.numisart.com /greekimp.html   (217 words)

The Roman Legions Founded in 165 or 166 AD by Marcus Aurelius for use in his campaigns against the Germanian Marcomanni tribe. AD: During the reign of Diocletian a sub-unit was transfered and established a base at Divitia (Deutz) near Cologne. It eventually became an independent legion, II Italica Divitensium, and was active in Constantine's march on Rome and the battle of the Milvian Bridge in 312 AD. www.unrv.com /military/legions.php   (2097 words)

[No title] Between the time of Augustus and the end of the 4th century AD, Greek-speaking provinces of the Empire issued their own coins - These coins bear Greek inscriptions and are usually very different from the Imperial issues. Scarce AE18 of Septimius Severus (193-211 AD) from AE27 of Geta as Augustus (209-212 AD) from www.ancientcoins.ca /provincialf2.html   (1017 words)

Coinage of Caracalla Born in Lugdunum,as Septimus Bassianus, he was renamed Marcus Aurelius Antoninus in 196 AD, but is most commonly known by the nickname "Caracalla", for his reported preference for wearing the caracallus, or hooded cloak favored by the Germanian tribes. In 209 AD, his brother Geta was also raised to the rank of Augustus, a clear sign that their father intended them to rule the empire jointly after his own death. However, after the death of Severus in 211 AD, the thought of sharing the imperial power with his brother proved to be intolerable to Caracalla, and he had Geta murdered, just short of the one year anniversary of their joint reign. www.celatorsart.com /cara_legends.html   (280 words)

FR Doc 05-22307 This proposed AD results from reports of the Camloc fasteners on the sidewall of the center pedestal disengaging and interfering with an inboard rudder pedal. We are proposing this AD to prevent these fasteners from disengaging and interfering with an inboard rudder pedal, which could reduce directional controllability of the airplane. This proposed AD would not have a substantial direct effect on the States, on the relationship between the National Government and the States, or on the distribution of power and responsibilities among the various levels of government. a257.g.akamaitech.net /7/257/2422/01jan20051800/edocket.access.gpo.gov/2005/05-22307.htm   (1740 words)

TIMELINE 2nd CENTURY page of ULTIMATE SCIENCE FICTION WEB GUIDE AD 350-370) Flavius Eutropius, a contemporary of Ammianus Marcellinus, and fellow soldier under Julian in the Persian campaign, became the court historian for the emperor Valens (364-378). His description of Claudius' conquest of Britain in AD 43 is based partly on Tacitus: "He made war upon Britain, which none of the Romans after Julius Caesar had meddled with; and conquering it by Cnaeus Centius and Aulus Plautius, illustrious and noble gentlemen, he had a famous triumph. He added likewise some islands, lying in the ocean beyond Britain, to the Roman Empire, which are called Orcades; and gave the name of Britannicus to his son." (VII, 13) In discussing Nero's reign, Eutropius refers to Boudicca's rebellion: "He [Nero] attempted no conquest in the military way, and very nearly lost Britain. www.magicdragon.com /UltimateSF/timeline2.html   (9588 words)

Middle Imperial Romans (193 AD-324 AD) - DBA II/64ab Severus Alexander held the purple for nearly fifteen years (222-235 AD), although power was largely held by a council consisting of his mother Julia Mamea, his grandmother Julia Maesa and the two Praetorian Prefects Ulpian and Paulus. In 234 AD, Alexander was encamped at Mainz in Upper Germany preparing for a campaign across the Rhine, when he engaged in negotiations with the Germans offering gold for peace. In 284 AD, he was campaigning in Britain, but marched south in early 285 to supress the rebellion of Iulianus, who was defeated near Verona. fanaticus.org /DBA/armies/II64/index.html   (3310 words)

FR Doc 05-24246 This new action revises the proposed AD by adding repetitive inspections of the static port heaters and insulators and revising the functional test of the static port heater. The actions specified by this new proposed AD are intended to prevent an electrical short of the static port heater from sparking and igniting the insulation blanket adjacent to the static port heater, which could result in smoke and/or fire in the cabin area. Note 1: For the purposes of this AD, a general visual inspection is: ``A visual examination of an interior or exterior area, installation or assembly to detect obvious damage, failure or irregularity. a257.g.akamaitech.net /7/257/2422/01jan20051800/edocket.access.gpo.gov/2005/05-24246.htm   (4403 words)

Roman Emperors - DIR Battle Descriptions Battle of Ad Decimum, A.D. Battle fought as part of Roman invasion of Vandal Africa on September 13th, 533 during the reign of Justinian, at the tenth milestone (Ad Decimum) south of Carthage. Battle of the Teutoburg Forest, A.D. During Augustus's reign (27 B.C.-14 A.D..), probably the greatest disaster suffered by the Romans was the defeat in the Teutoburg forest when the former proconsul of Africa, Publius Quinctilius Varus, together with three legions (XVII, XVIII, and XIX), six cohorts and three squadrons of cavalry (alae) were practically slaughtered. Battle of Yarmuk, A.D. During the reign of Heraclius this battle was fought between Romans and Arabs in the Jordan valley in the Roman province of Palestine. www.roman-emperors.org /assobd.htm   (2604 words)

ROMFI - Roman Coins   (Site not responding. Last check: 2007-11-02) An added value for People, Collectors, Museums, Institutions who submit data is that while sharing their knowledge with the world, they build up a digital catalog of their own collection that is protected with a password, and so only they can see their collection. Severus Alexander AD 222-235 - Denarius - (ob) IMP C M AVR SEV ALEXAND AVG Draped and cuirassed bust, laureate, to rt / (rev) LIBERALITAS AVG Liberalitas to l. Carinus AD 283-285 - Aureus - (ob) MAGNIAE VRBICAE AVG Draped bust with diadem to rt / (rev) CONCORD-I-A AVGG Concordia seated to l. www.ifyoubuildittheywill.com /coin-roman.htm   (5795 words)

Faculty These efforts have resulted in the development of several atypical anthracyclines whose mechanisms of action have recently be shown to be distinct from typical nuclear-targeted anthracyclines such as doxorubicin or daunorubicin. Among this class of compounds are N-benzyladriamycin-14-valerate (AD 198), a patented compound (M. Israel/UT Research Corp.) that appears to circumvent all known clinically relevant mechanisms of drug resistance and is non-cardiotoxic, and N-trifluoroacetyladriamycin-14-valerate (AD 32/Valrubicin/Valstar®), which is currently FDA-approved for bladder tumors as a chemotherapeutic alternative to systectomy. Further, Dr. Sweatman’s investigations in AD 198 and protein kinase C interactions have led to the identification of this essential signaling enzyme as a target for AD 198 and other closely related anthracyclines. www.utmem.edu /pharmacology/reserach_cancer.html   (2003 words)

Interaction of the Novel Anthracycline Antitumor Agent N-Benzyladriamycin-14-valerate with the C1-Regulatory Domain of ... Kinase activity was measured as described in "Materials and Methods." Kinase activity in the absence of PDBu was 17.7 +/- 2.2 pmol of phosphate/min and was unaffected by AD 198. H]PDBu and increasing concentrations of AD 198 as indicated. Of significance, the cytotoxicity of AD 198 occurs mct.aacrjournals.org /cgi/content/full/1/7/483   (5924 words)

MRA - Crown Collection of Antiquarian Coins After his father had quelled the chaos in Asia Minor in 195 AD, Bassinius was re-named as Marcus Aurelius Antonius Pius Augustus and was hailed as “Caesar” at the age of about seven. Following the success of the Parthian campaign in 198 AD, on January 28 Antoninus was raised from “Caesar” to “Augustus” at ten years old. The Emperor Caracalla ruled until the year 217 AD, when he was murder by the Prefect of the Praetorian Guard, Macrinus, while traveling from Edessa to Carrhae (Sear 197). www.minervanet.org /archives/a13.htm   (676 words)

VCoins - The Online Coin Show for Ancient Coins, US Coins, and World Coins Marcian, 450 - 457 A.D. Marcus Aemilius Scaurus & Publius Plautius Hypsaeus, 58 B.C. Marcus Aurelius & Lucius Verus, Phoenicia, Arados. Philip I the Arab, 244 - 249 A.D., Billon Tetradrachm of Syria, Antioch. Philip I the Arab, 244 - 249 A.D., Billon Tetradrachm of Syria, EXTREMLY RARE. www.vcoins.com /ancient/holyland/store/pricelist.asp   (400 words)

Christian grooming and clothing Novatian (circa 235 AD), 5.591, formerly attributed to Cyprian. Cyprian (circa 250 AD), 5.431; extended discussion: 5.430-5.436. You wish, O Christian woman, that the matrons should be as the ladies of the world. www.bibletopics.com /biblestudy/141.htm   (2100 words)

Ancient Coins There are many of these coins in excellent condition offered on the market every day at reasonable prices. The simple truth is: "If there were a lot of any ancient coins made, there will be a lot available today." The most common of the ancient coins are the Roman coins which were minted between 200 and 400 AD. AD 305-306 Constantius I. Chlorus Rev - Genius of the Ceasars www.wcoins.com /Ancients.htm   (436 words)

Jak's View From Vancouver: Brief Notices   (Site not responding. Last check: 2007-11-02) A spokesman for Britain's Ministry of Defence told CNN Sunday that it had a duty to allow members of the forces to practice their religion. He added that the MoD was an "equal opportunities employer" which did not stop anyone having their own religious values." "In AD 198–99, the citizens of Hatra (the remains of this city are located south of Masul, Iraq) successfully defended their city from a Roman attack by the use of clay-pot bombs likely filled with scorpions and other venomous insects gathered from the surrounding desert. jakking.typepad.com /daily/brief_notices/index.html   (5823 words)

Catholic Culture : Document Library : Was Peter the First Pope? Bishop Eusebius of Caesarea, The Chronicle, AD 303, "[In the second] year of the two hundredth and fifth Olympiad [AD 42]: The Apostle Peter, after he has established the church in Antioch, is sent to Rome, where he remains as a bishop of that city, preaching the gospel for twenty-five years." Caius, Disputation with Proclus, AD 198, quoted by Bishop Eusebius in Church History 2:25:5, "It is recorded that Paul was beheaded in Rome itself, and Peter, likewise, was crucified, during the reign [of the Emperor Nero]. With that church, because of its superior origin, all the churches must agree, that is, all the faithful in the whole world, and it is in her that the faithful everywhere have maintained the apostolic tradition. www.catholiculture.com /docs/doc_view.cfm?recnum=635   (9519 words)

Pars Coins PERSIA: SAMANID, Abdul Malik Ibn Nuh 954-961 AD. The Roman Emperors: A Biographical Guide to the Rulers of Imperial Rome, 31 BC.- 476 AD., by Michael Grant. Roman Empire: Antoninus Pius & Marcus Aurelius 138-161 AD. www.parscoins.com /shoppingtext.asp   (429 words)

Bijlage 7   (Site not responding. Last check: 2007-11-02) , CLAUDIUS, AD 41 - 54, AR,BMC9.1,4,SEAR unl. Rev: Car driven by 4 elephants, driver on each. Rev: Ausgus seated in quadriga of elephants l. home.concepts.nl /~bjrlind/romeColonies2.htm   (90 words)

Chatter - Chicago Coin Club - March, 2006 Steve Zitowsky: France S. Franc pattern from 1848; from German East Africa an 1890 silver proof rupie struck in Berlin, an 1908J silver rupie proof struck in Hamburg and three 1916 20-heller coins struck at the Taveta Mint and made from a salvaged ship and empty British shell casings. One of his first altered coins was a 1916 US dime with an added D mintmark. The D was added using electroplating, by selectively adding silver in the mintmark area while the surrounding area was masked; pronounced genuine by the Treasury Department. www.chicagocoinclub.org /chatter/2006/Mar   (2904 words)

Aero-News Network: The Aviation and Aerospace World's Daily/Real-Time News and Information Service The Sport Cub production and delivery rate is now scheduled to accelerate to one per week over the next four to six weeks -- and on to two per week near the turn of the year. These are interesting jobs and the positions/hours vary according to the skills possessed by the applicant, and the needs we have at any given time -- but you'll find that we can adapt the workflow to a number of criteria for the right person(s). None of the 89 passengers aboard the airliner were hurt; neither was the pilot of the fighter. www.aero-news.net /index.cfm?ContentBlockID=38c87cfe-ab54-467d-8b86-c69b4b7e9405&   (13394 words)

Ancient Art Gallery Traces from the Past - Roman coins   (Site not responding. Last check: 2007-11-02) Denarius, struck 214 AD Obverse: ANTONINVS PIVS AVG GERM Reverse: PONTIF TR P X COS II, Caracalla standing right, holding spear and parazonium, right foot on helmet. Reverse: PONTIF TR P VIII COS II, Mars standing left, holding reversed spear and while resting right hand on shield. www.traces.nu /coins_roman.htm   (194 words)

Caracalla imitations Caracalla (Caesar AD 196-198, Augustus AD 198 - 217) and his wife Plautilla Severus Alexander BMC 57 (of AD 222) is quite similar and is the probable prototype. The "BRIT" termination is attributed to AD 210-213. esty.ancients.info /imit/imitcara.html   (249 words)

Chi-Rho Coins - Roman Provincial Coins Obverse: Diademed, draped bust of Severa left facing on crescent. Metal is nicer (much less porous) than many seen recently from this region. Reverse: Athena standing holding Nike, resting hand on shield, L (Delta) in left field. www.chi-rho.com /xp_prov.htm   (256 words)

rome_severans2   (Site not responding. Last check: 2007-11-02) Roman Empire, Elagabalus (218-222 AD), silver denarius, struck 219-20 AD Roman Empire, Elagabalus (218-22 AD), silver denarius, struck 218 AD. Greek Imperial, Severus Alexander (222-35 AD), bronze AE37 of Amasia (Pontus), struck 232/3 AD. www.rudnik.com /rome/severans2   (2801 words)

New Roman III, March 29, '03   (Site not responding. Last check: 2007-11-02) Greek Imperial, Julia Domna (193-217 AD), wife of Sept. Severus (193-211 AD), AE17 of Nikopolis (Moesia Inferior) Roman Empire, Julia Maesa, grandmother of Elagabalus (218-22 AD) and Sev. Greek Imperial, Philip I (244-9 AD), billon tetradrachm of Antiochia ad Orontem (Syria), struck 246/7 AD, 11.76g www.rudnik.com /whatisnew/htmls/NewRoman3Mar2903.html   (1205 words)

GreenSage Classified Ad Submission Form Who do you wish your ad to target? You will receive an online bill from us via PayPal. Once payment is received, your ad will be published. www.greensage.com /classifieds/classifiedsPform.html   (61 words)

Muslim Matrimonials Ad 198 - Marriage Personals, Free, Islam .tc Muslim Matrimonials Ad 198 - Marriage Personals, Free, Islam.tc Islam.tc > Muslim Matrimonials > Male Ads > View Ad 198 << 199 - View previous Male ad www.islam.tc /ads/view.php?ad=198   (108 words)

Geta, Roman Imperial Coins of, at WildWinds.com Geta AR Tetradrachm of Laodikeia ad Mare, Syria. ATOC • TO B, eagle standing left, wreath in beak, star between legs. Circa A.D. C, laureate bust right / OV IAC, river-god seated left, left arm resting on urn, small human figure beneath to right collecting water. www.wildwinds.com /coins/ric/geta/i.html   (3453 words)

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