| |
| | Patent 6,448,389 |
 | | For example, such a composition may contain one or more HCMV proteins (e.g., the isolated, purified gB protein described in the examples below), a whole virus (e.g., semipurified Towne strain HCMV virion), or recombinant HCMV viruses. |
 | | Suitable recombinant viruses are well known to those of skill in the art and include, e.g., the Ad-gB virus [G. Marshall et al, (1990), cited above, and EP 389 286; the Ad-gB-IE-exon-4 virus [WO 94/17810]; the Ad-gB fragment viruses [WO Other suitable HCMV vaccinal compositions are well known to those of skill in the art. |
 | | A p.DELTA.RC-pp65 plasmid, said plasmid comprising the human cytomegalovirus (HCMV) gene encoding the HCMV pp65 tegument protein under the control of regulatory sequences which direct expression of the pp65 antigen in mammalian cells. |
| www.pharmcast.com /Patents/Yr2002/September2002/091002/6448389_DNA091002.htm (2624 words) |
|