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Topic: 45,X

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	Turner syndrome - Wikipedia, the free encyclopedia
		The first published report of a female with a 45,X karyotype was in 1959 by Dr. Charles Ford and colleagues in Harwell, Oxfordshire and Guy's Hospital in London.
		The higher prevalence in the group of pure 45X monosomy is primarily due to a significant difference in the prevalence of aortic valve abnormalities and aortic coarctation, the two most common cardiovascular malformations.
		Though according to Sybert, 1998 there is inadequate data to allow conclusions for regarding phenotype-karyotype correlations in regard to cardiovascular malformations in Turner syndrome because the number of individuals with the less common karyotype groups that has been studied is too small.
	en.wikipedia.org /wiki/45,X (3424 words)

	Mosaicism for 45,X cell line may accentuate the severity of spermatogenic defects in men with AZFc deletion -- ...
		Pure 45,X chromosomal constitution is known to result in incomplete ovarian development (streak gonads in the adult).
		Surprisingly, in five of these AZF deleted males who were karyotyped, a second cell line, 45,X, was found in three of them (a frequency of at least 50%).
		The two patients with large deletions and a coexisting 45,X cell line had both azoospermia and complete maturation arrest with no secondary spermatocytes, whereas patients with just AZFc deletions and a pure 46,XY karyotype had less severe phenotypes, namely azoospermia or severe oligospermia and incomplete maturation arrest with the presence of secondary spermatocytes or hypospermatogenesis.
	jmg.bmj.com /cgi/content/full/38/11/798 (3341 words)

	X chromosome - Genetics Home Reference
		The missing genetic material affects development and causes the characteristic features of the condition, including short stature, learning problems, and inability to conceive a child (infertility).
		About half of individuals with Turner syndrome have monosomy X (45,X), which means each cell in an individual's body has only one copy of the X chromosome instead of the usual two sex chromosomes.
		Turner syndrome can also occur if one of the sex chromosomes is partially missing or rearranged rather than completely missing.
	ghr.nlm.nih.gov /chromosome=X (952 words)

	Nikon Fieldscope 20 - 45 x 60 Spotting Scope Outfit (Site not responding. Last check: 2007-10-11)
		Includes 60mm straight body scope, 20X - 45X zoom eye-piece, Bogen full size tripod, & window mount.
		Nikon Fieldscope 20X - 45X Zoom or 25X - 56X Zoom Eyepiece
		Is a 20X - 45X eyepiece on the 60mm body Fieldscope or a 25X - 56X eyepiece on the 82mm body Fieldscope
	www.exploreproducts.com /nikonfieldscope320-45x60spottingscope.htm (446 words)

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