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	5' cap - Wikipedia, the free encyclopedia
		The 5' cap is a specially altered dinucleotide end to the 5' end of preliminary messenger RNA as found in eukaryotes.
		Capping ensures the messenger RNA's stability while it undergoes translation in the process of protein synthesis, and is a highly regulated process which occurs in the nucleus.
		As soon as the 5' end of the new transcript emerges the enzymes transfer to it and begin the capping process (this is a similar kind of mechanism to ensure capping as for polyadenylation).
	en.wikipedia.org /wiki/5'_cap (507 words)

	Messenger RNA - Wikipedia, the free encyclopedia
		G cap, is a modified guanine nucleotide that has been added to the "front" or 5' end of the messenger RNA shortly after the start of transcription.
		The 5' cap consists of a terminal 7-methylguanosine residue which is linked through a 5'-5'-triphosphate bond to the first transcribed nucleotide.
		After the 5' end has been capped, it is released from the cap-synthesizing complex and is subsequently bound by a cap-binding complex associated with RNA polymerase.
	en.wikipedia.org /wiki/Messenger_RNA (1655 words)

	Modifications of the 5' Cap of mRNAs during Xenopus Oocyte Maturation: Independence from Changes in Poly(A) Length and ...
		mRNA in the absence of cap ribose methylation.
		Nucleoside 5'-monophosphates and cap dinucleotides are as indicated in the legend for Fig.
		Non-methylated guanosine as the 5' terminus of capped mRNA from insect oocytes.
	mcb.asm.org /cgi/content/full/18/10/6152 (6877 words)

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	www.capinc.org (7223 words)

	BIOL414/614 at UMBC - roles_of_the_5_prime_cap
		Ultimately, studies suggest that the binding of CBC to the 5' cap facilitates an early stage in the assembly of the splicing complex, thereby, illustrating another vital function for 5' capping (Lewis et al 1996a).
		Finally, eIF-4E is a translation initiation factor that recognizes the 5' cap on mRNA transcripts, binds to it, and triggers mRNA binding to ribosomes.
		This direct connection between the 5' cap and translation initiation demonstrates the importance of the 5' cap in initiating the translation of mRNA transcripts into protein(Lejbkowicz et al 1992).
	www.umbc.edu /bioclass/biol414/wiki/index.php?page=roles_of_the_5_prime_cap (303 words)

	Phosphorylation of eIF4E attenuates its interaction with mRNA 5' cap analogs by electrostatic repulsion: ...
		quantitatively the cap affinity for phosphorylated and unphosphorylated
		The shift of the titration curve to a higher concentration of the cap analog for phosphorylated versus unphosphorylated eIF4E results from weaker binding affinity of the cap analogs for the protein.
		Syntheses and purification of mono- and dinucleotide cap analogs
	www.rnajournal.org /cgi/content/full/9/1/52 (5352 words)

	The Pre-mRNA 5' Cap Determines Whether U6 Small Nuclear RNA Succeeds U1 Small Nuclear Ribonucleoprotein Particle at 5' ...
		A role for the 5' cap structure in pre-mRNA splicing was shown by early studies in extracts.
		Cap analogues and SR proteins were preincubated with the extract before the addition of the pre-mRNA and splicing mix.
		Preferential excision of the 5' proximal intron from messenger RNA precursors with 2 introns as mediated by the cap structure.
	mcb.asm.org /cgi/content/full/18/12/7510 (7754 words)

	Stabilization of Eukaryotic Initiation Factor 4E Binding to the mRNA 5'-Cap by Domains of eIF4G -- von der Haar et al. ...
		However, the efficiency of removal of the cap analogue during the purification of eIF4E has been questioned (21).
		5 µg of each protein were loaded onto an SDS-polyacrylamide gel electrophoresis gel and stained with Coomassie Blue.
		In the presence of cap analogue the association is completely prevented (gray line), whereas GDP at the same concentration does not strongly affect the association with the chip (broken gray line).
	www.jbc.org /cgi/content/full/275/39/30551 (4641 words)

	The Box C/D motif directs snoRNA 5'-cap hypermethylation -- Speckmann et al. 28 (22): 4467 -- Nucleic Acids Research (Site not responding. Last check: 2007-10-13)
		The 5 bp terminal stem is denoted by an arrow.
		cap structure (39) is not recognized by either antibody.
		for cap hypermethylation is not included among the bound Sm proteins (58) and remains unidentified.
	nar.oxfordjournals.org /cgi/content/full/28/22/4467 (3545 words)

	Cap-Independent Translational Enhancement by the 3' Untranslated Region of Red Clover Necrotic Mosaic Virus RNA1 -- ...
		Transcripts containing the precise viral 5' UTR and the Luc gene followed by various parts of the 3' UTR are diagrammed on the left.
		absence of the 5' cap structure (13, 46).
		Enzymatic removal of the 5' terminal methylated blocked structure of tobacco mosaic virus RNA and its effects on infectivity and reconstitution with coat protein.
	jvi.asm.org /cgi/content/full/77/22/12113 (5637 words)

	SparkNotes: Post-Transcriptional RNA Processing: The 5' Cap and the Poly A Tail
		At the end of transcription, the 5' end of the RNA transcript contains a free triphosphate group since it was the first incorporated nucleotide in the chain.
		The cap is formed through a 5'-5' linkage between the two substrates such that the GTP molecule is oriented in the opposite direction as the other nucleotides in the RNA transcript chain.
		Once in place, the cap plays a role in the ribosomal recognition of messenger RNA during translation into a protein.
	www.sparknotes.com /biology/molecular/posttranscription/section1.html (406 words)

	Discrimination between mono[ndash]and trimethylated cap structures by two isoforms of Caenorhabditis elegans eIF4E
		G-containing caps by mRNAs through the process of trans-splicing, in which a 22 nucleotide spliced leader is transferred from the 5'-end of an snRNA to an acceptor site in the 5' end of the pre-mRNA (Blumenthal, 1998).
		In all three cases, the changes in cap selectivity caused by substitutions in the 3−4 loop are attenuated by substitutions in the 1−2 loop, causing the proteins to behave more like wt IFE-5.
		It is conceivable that the formation of this disulfide bond serves as a reversible switch that responds to the redox state of the cell, as has recently been reported for the molecular chaperone Hsp33 (Jakob et al., 1999).
	www.nature.com /emboj/journal/v21/n17/full/7594689a.html (7452 words)

	The Candida albicans gene for mRNA 5'-cap methyltransferase: identification of additional residues essential for ...
		Expression and purification of the recombinant cap MTase.
		Gillian-Daniel, D. L., Gray, N. K., Astrom, J., Barkoff, A. and Wickens, M. Modifications of the 5' cap of mRNA during Xenopus oocyte maturation: independence from changes in poly(A) length and impact on translation.
		Shuman, S., Liu, Y. and Schwer, B. Covalent catalysis in nucleotidyl transfer reaction: essential motifs in Saccharomyces cerevisiae RNA capping enzyme are conserved in Schizosaccharomyces pombe and viral capping enzymes and among polynucleotide ligases.
	mic.sgmjournals.org /cgi/content/full/145/11/3023 (4912 words)

	5.2 CAP AND ROTOR - V8 Dodge Dakota (Site not responding. Last check: 2007-10-13)
		Go to any parts store and ask for a cap and rotor for a 1999 5.2 Dak, and they should have the part number.
		If you go with the coil and MSD 6A, change out the stock cap and rotor for one with brass contacts (I used Borg Warner).
		I have already installed a NAPA cap and rotor along with MSD super conductor wires.
	www.dodgedakotas.com /boards/v8/140.html (882 words)

	The Pre-mRNA 5' Cap Determines Whether U6 Small Nuclear RNA Succeeds U1 Small Nuclear Ribonucleoprotein Particle at 5' ...
		We demonstrate that the cap alters the kinetic
		cap acts on both, even though one is substantially preferred for
		Inhibition of splicing by a cap analogue is correlated
	mcb.asm.org /cgi/content/abstract/18/12/7510 (361 words)

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	Nokia Calls for 5% Cap on 3G Patent Royalties
		Finnish cell phone giant Nokia Corp. (Quote, Chart) on Wednesday urged competitors to place a hard cap on royalty rates for 3G patents, arguing that such a move would promote the spread of the WCDMA technology.
		Under the Nokia proposal, which would be applicable to both network gear and phones, patent holders would agree to limit the cumulative royalty rate to a maximum of 5 percent, regardless of how many patents the equipment includes.
		Royalty rates for the much-vaunted Wideband Code Division Multiple Access (WCDMA) technology are generally computed as a percentage of the price of the equipment using patents.
	www.internetnews.com /dev-news/article.php/1041561 (628 words)

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		>5.2 or 4.2 gallon capacity for use with standard screw-in caps or with flush locking caps.
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	www.nextag.com /5-cap-gallon/search-html (379 words)

	Tekelec :: Solutions :: Class 5 Cap and Grow
		Carriers can “cap” a legacy Class 5 switch by moving traffic to Tekelec’s next-generation switching products and stop further investment in their legacy platforms.
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	www.tekelec.com /solutions/s_detail.asp?id=10 (149 words)

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		Assortment of Grade 5 Cap Screws, Hex Nuts, Lockwashers, and Flat Washers - Coarse Thread.
		25 of 1/4" x 1/2" Grade 5 Cap Screws
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