| | 50S and antibiotics (Site not responding. Last check: ) |
 | | Fall 2001 we succeded to publish almost on the same day the structure of the 50S ribosomal subunit from Deinococcus radiodurans (in Cell) and structure of four complexes of the same subunit with different, clinically important antibiotics (Chloramphenicol, Clindamycin, Erythromycin, Clarythromycin und Roxythromycin). |
 | | The structure of the 50S subunit from Deinococcus radiodurans togehter with positions for the bound antibiotics Sparsomycin (green),Chloramphenicol (purple), Clindamycin (orange) und Erythromycin (red, standing for makrolides). |
 | | The quinolylallyl reaches domain II (see 50S structure), a common way of macrolide derivatives to overcome typical resistances (as long as they are based on target modification). |
| www.riboworld.com /antib/50santib-eng.html (2008 words) |