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Topic: 717 E3 y


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In the News (Sat 26 May 12)

  
  Rsp5 Ubiquitin-Protein Ligase Mediates DNA Damage-Induced Degradation of the Large Subunit of RNA Polymerase II in ...
Rsp5 is an E3 ubiquitin-protein ligase of Saccharomyces cerevisiae that belongs to the hect domain family of E3 proteins.
Purified hect E3 proteins (human E6-AP, human Rpf1 [WW-hect; amino acids 193 to 901], yeast Rsp5, and the mutant of Rsp5 with a change of the active-site Cys to Ala [C-A]) were incubated as indicated with Rpb1 in the presence of ATP, ubiquitin, E1 enzyme, and E2 enzyme (Arabidopsis thaliana Ubc8) as previously described (18).
Rsp5 is the only hect E3 protein in yeast that has a C2 domain and WW domains, while at least seven human hect E3s with C2 and WW domains have been identified.
mcb.asm.org /cgi/content/full/19/10/6972   (6676 words)

  
 Deletion of the NOT4 gene impairs hyphal development and pathogenicity in Candida albicans -- Krueger et al. 150 (1): ...
Bai, Y., Salvadore, C., Chiang, Y. C., Collart, M. A., Liu, H. and Denis, C. The CCR4 and CAF1 proteins of the CCR4–NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5.
Chen, J., Chiang, Y. and Denis, C. CCR4, a 3'-5' poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase.
Liu, H. Y., Badarinarayana, V., Audino, D. C., Rappsilber, J., Mann, M. and Denis, C. The NOT proteins are part of the CCR4 transcriptional complex and affect gene expression both positively and negatively.
mic.sgmjournals.org /cgi/content/full/150/1/229   (5059 words)

  
 Denglab Publications
Kraft E, Stone SL, Ma L, Su N, Gao Y, Lau OS, Deng XW, Callis J. Genome Analysis and Functional Characterization of the E2 and RING-Type E3 Ligase Ubiquitination Enzymes of Arabidopsis.
Tiling microarray analysis of rice chromosome 10 to identify the transcriptome and relate its expression to chromosomal architecture.
Evidence for a physical association of the COP9 signalosome, the proteasome, and specific SCF E3 ligases in vivo.
www.yale.edu /denglab/paper_denglab.htm   (1768 words)

  
 Null Mutation of AtCUL1 Causes Arrest in Early Embryogenesis in Arabidopsis -- Shen et al. 13 (6): 1916 -- Molecular ...
Furukawa, M., Zhang, Y., McCarville, J., Ohta, T., and Xiong, Y. The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1.
Genschik, P., Criqui, M.C., Parmentier, Y., Derevier, A., and Fleck, J. Cell cycle-dependent proteolysis in plants: identification of the destruction box pathway and metaphase arrest produced by the proteasome inhibitor MG132.
Wang, Y., Penfold, S., Tang, X., Hattori, N., Riley, P., Harper, J.W., Cross, J.C., and Tyers, M. Deletion of the Cul1 gene in mice causes arrest in early embryogenesis and accumulation of cyclin E. Curr.
www.molbiolcell.org /cgi/content/full/13/6/1916   (6728 words)

  
 No Title
Masaike, Y. Masuda, Y. Matsuda, G. Mitchell, S. Penttilä, H. Postma, N. Roberson, S. Seestrom, E. Sharapov, S. Stephenson, Y.-F. Yen and V. Yuan, Physical Review C, ``Observation of a Large Parity Non-conserving Effect in Xe'', J. ymanski, W.
Lowie, A. Masaike, Y. Matsuda, S. Penttilä, H. Postma, N. Roberson, S. Seestrom, E. Sharapov, D. Smith, S. Stephenson, Yi-Fen Yen, and V. Yuan, Applications of Accelerators in Research and Industry (AIP Conference Proceedings 475, Woodbury, New York, 1999) 219.
Delheij, F. Gunsing T. Haseyama, J. Knudson, L. Lowie, A. Masaike, Y. Masuda, Y. Matsuda, G. Mitchell, S. Penttilä, N. Roberson, S. Seestrom, E. Sharapov, H. Shimizu, S. Stephenson, Yi-Fen Yen, V. Yuan and L. Zanini, IV International Seminar on Interactions of Neutrons with Nuclei (Dubna, Russia, 1996) 101.
www.gettysburg.edu /~bcrawfor/beccv.html   (2294 words)

  
 Interaction and Transmission of Two Borrelia burgdorferi Sensu Stricto Strains in a Tick-Rodent Maintenance System -- ...
E3 and the control groups were designated C1 and C3.
E1, infected with BL206 and challenged with B348; E3, infected with B348 and challenged with BL206; C1, infected and challenged with BL206; C3, infected and challenged with B348.
E3 was infected with B348 and challenged with BL206) were permissive
aem.asm.org /cgi/content/full/70/11/6783   (3613 words)

  
 Human HRD1 Is an E3 Ubiquitin Ligase Involved in Degradation of Proteins from the Endoplasmic Reticulum -- Kikkert et ...
Human HRD1 Is an E3 Ubiquitin Ligase Involved in Degradation of Proteins from the Endoplasmic Reticulum -- Kikkert et al.
At present, three classes of E3 ligases are recognized.
E3 ligases are available, each of which may be specific for
www.jbc.org /cgi/content/full/279/5/3525   (6269 words)

  
 The Agrin/MuSK Signaling Pathway Is Spatially Segregated from the Neuregulin/ErbB Receptor Signaling Pathway at the ...
Lenferink AEG, Pinkas-Kramarski R, van de Poll MLM, van Vugt MJH, Klapper LN, Tzahar E, Waterman H, Sela M, van Zeolen EJJ, Yarden Y (1998) Differential endocytic routing of homo- and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers.
Peles E, Ben-Levy R, Tzahar E, Liu N, Wen D, Yarden Y (1993) Cell-type specific interaction of Neu differentiation factor (NDF/heregulin) with Neu/HER-2 suggests complex ligand-receptor relationships.
Waterman H, Sabanai I, Geiger B, Yarden Y (1998) Alternative intracellular routing of ErbB receptors may determine signaling potency.
www.jneurosci.org /cgi/content/full/20/23/8762   (6016 words)

  
 [No title]   (Site not responding. Last check: 2007-10-24)
Citation: Journal of Biological Chemistry 273: 24770-24774 1998 Type: ARTICLE Genes: Abstract: Tyrosine O-sulfation, a common post-translational modification in eukaryotes, is mediated by Golgi enzymes that catalyze the transfer of the sulfuryl group from 3'-phosphoadenosine 5'-phosphosulfate to tyrosine residues in polypeptides.
The lining of the buccal capsule of Z. punctata and additional Cephalobidae includes four sets of muscular radial cells, ma, mb, me and md, in contrast to C. elegans and additional Rhabditidae, which has two sets of epithelial cells (el, e3) and two sets of muscle cells (ml, m2).
Cell lineage of a nematode closely related to Z. punctata, Cephalobus cubaensis, supports the hypothesis that in cephalobids the el and e3 cells become hypodermal cells or are programmed to die.
biosci.umn.edu /CGC/Bibliography/3201.txt   (16220 words)

  
 c-Jun Triggers Apoptosis in Human Vascular Endothelial Cells -- Wang et al. 85 (5): 387 -- Circulation Research   (Site not responding. Last check: 2007-10-24)
Sawai H, Okazaki T, Yamamoto H, Okano H, Takeda Y, Tashima M, Sawada H, Okuma M, Ishikura H, Umehara H. Requirement of AP-1 for ceramide-induced apoptosis in human leukemia HL-60 cells.
Nakajima T, Yageta M, Shiotsu K, Morita K, Suzuki M, Tomooka Y, Oda K. Suppression of adenovirus E1A-induced apoptosis by mutated p53 is overcome by coexpression with Id proteins.
Shimizu R, Komatsu N, Nakamura Y, Nakauchi H, Nakabeppu Y, Miura Y. Role of c-jun in the inhibition of erythropoietin receptor-mediated apoptosis.
circres.ahajournals.org /cgi/content/full/85/5/387   (4274 words)

  
 The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin ...
Imai, Y., Soda, M., Inoue, H., Hattori, N., Mizuno, Y. and Takahashi, R. (2001) An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin.
Chung, K.K., Zhang, Y., Lim, K.L., Tanaka, Y., Huang, H., Gao, J., Ross, C.A., Dawson, V.L. and Dawson, T.M. (2001) Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease.
Imai, Y., Soda, M., Hatakeyama, S., Akagi, T., Hashikawa, T., Nakayama, K.I. and Takahashi, R. (2002) CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity.
hmg.oxfordjournals.org /cgi/content/full/12/20/2587   (6559 words)

  
 Small Ubiquitin-Like Modifier 1 (SUMO-1) Modification of the Synergy Control Motif of Ad4 Binding Protein/Steroidogenic ...
Luo X, Ikeda Y, Parker KL 1994 A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation.
Sadovsky Y, Crawford PA, Woodson KG, Polish JA, Clements MA, Tourtellotte LM, Simburger K, Milbrandt J 1995 Mice deficient in the orphan receptor steroidogenic factor 1 lack adrenal glands and gonads but express P450 side-chain-cleavage enzyme in the placenta and have normal embryonic serum levels of corticosteroids.
Tremblay JJ, Marcil A, Gauthier Y, Drouin J 1999 Ptx1 regulates SF-1 activity by an interaction that mimics the role of the ligand-binding domain.
mend.endojournals.org /cgi/content/full/18/10/2451   (7075 words)

  
 A Targeted Partial Invalidation of the Insulin-Like Growth Factor I Receptor Gene in Mice Causes a Postnatal Growth ...
Bessone S, Vidal F, Le Bouc Y, Epelbaum J, Bluet-Pajot MT, Darmon M 1999 EMK protein kinase-null mice: dwarfism and hypofertility associated with alterations in the somatotrope and prolactin pathways.
Binoux M, Seurin D, Lassarre C, Gourmelen M 1984 Preferential measurement of insulin-like growth factor (IGF) I-related peptides in serum with the aid of IGF binding proteins (IGFBPs) produced by rat liver in culture.
Lakso M, Pichel JG, Gorman JR, Sauer B, Okamoto Y, Lee E, Alt FW, Westphal H 1996 Efficient in vivo manipulation of mouse genomic sequences at the zygote stage.
endo.endojournals.org /cgi/content/full/141/7/2557   (7065 words)

  
 Efficacy with a Replication-selective Adenovirus Plus Cisplatin-based Chemotherapy: Dependence on Sequencing but not ...
Chung K. Y., Mukhopadhyay T., Kim J., Casson A., Ro J. Y., Goepfert H., Hong W. K., Roth J. Discordant p53 gene mutations in primary head and neck cancers and corresponding second primary cancers of the upper aerodigestive tract.
Shin D. M., Kim J., Ro J. Y., Hittelman J., Roth J. A., Hong W. K., Hittelman W. Activation of p53 gene expression in premalignant lesions during head and neck tumorigenesis.
Yaginuma Y., Westphal H. Abnormal structure and function of the p53 gene in human ovarian carcinoma cell lines.
clincancerres.aacrjournals.org /cgi/content/full/6/12/4908   (4655 words)

  
 IGN: Prey Review
In this context, it seems unusual that someone would resurrect a dormant idea -- Prey -- and bring it to the masses, instead of sticking to tried-and-true franchises and sequels.
Add in local gravity wells, spirit walking, and a stream of puzzles that take all of these elements into account, and what you end up with is an environment that transcends its individual gimmicks.
I have to say, though, that your initiation into spirit walking is as simple as it gets (hint: you press the Y button), and suddenly you're a dude who can leave his body at any time, indefinitely, and walk through force field and move around invisibly in the presence of the enemy.
xbox360.ign.com /articles/717/717824p1.html   (736 words)

  
 Mind Bomb-2 Is an E3 Ligase for Notch Ligand -- Koo et al. 280 (23): 22335 -- Journal of Biological Chemistry
Mind Bomb-2 Is an E3 Ligase for Notch Ligand -- Koo et al.
Mib2 Is a Mib1 Paralogue—Zebrafish Mib1 is a E3 ubiquitin
Mib2 Is an E3 Ubiquitin Ligase—Zebrafish Mib1 has an E3 ubiquitin ligase activity with Delta, both in vitro and in vivo
www.jbc.org /cgi/content/full/280/23/22335   (4897 words)

  
 [No title]
The court also noted that the Seventh Circuit had consistently held that screening procedures can rebut any inference of shared confidences or appearance of impropriety.
Stephens, 717 F.2d 417 (1983), and LaSalle National Bank v.
It first held that disqualification of the entire U.S. Attorney's Office was unnecessary because, in accordance with the I.R.P.C. and internal Justice Department standards, adequate screening measures were followed to ensure that Richmond did not share client confidences with the AUSAs in charge of the prosecution.
www.usdoj.gov /osg/briefs/1989/sg890014.txt   (3563 words)

  
 MDM2 and Prognosis -- Onel and Cordon-Cardo 2 (1): 1 -- Molecular Cancer Research
Oda, Y., Sakamoto, A., Satio, T., Kawauchi, S., Iwamoto, Y., and Tsuneyoshi, M. Molecular abnormalities of p53, MDM2, and H-ras in synovial sarcoma.
Bueso-Ramos, C. E., Yang, Y., de Leon, E., McCown, P., Stass, S. A., and Albitar, M. The human MDM-2 oncogene is overexpressed in leukemias.
Ko, J. L., Cheng, Y. W., Chang, S. L., Su, J. M., Chen, C. Y., and Lee, H. MDM2 mRNA expression is a favorable prognostic factor in non-small-cell lung cancer.
mcr.aacrjournals.org /cgi/content/full/2/1/1   (6261 words)

  
 In CA1 Pyramidal Neurons of the Hippocampus Protein Kinase C Regulates Calcium-Dependent Inactivation of NMDA Receptors ...
Mayer ML, Vyklicky Jr L, Clements J (1989) Regulation of NMDA receptor desensitization in mouse hippocampal neurons by glycine.
Medina I, Leinekugel X, Ben-Ari Y (1999) Calcium-dependent inactivation of the monosynaptic NMDA EPSCs in rat hippocampal neurons in culture.
Yamada Y, Chochi Y, Takamiya K, Sobue K, Inui M (1999) Modulation of the channel activity of the epsilon2/zeta1-subtype N-methyl-
www.jneurosci.org /cgi/content/full/20/12/4452   (5777 words)

  
 The Fgf8 signal causes cerebellar differentiation by activating the Ras-ERK signaling pathway -- Sato and Nakamura 131 ...
Corson, L. B., Yamanaka, Y., Lai, K. and Rossant, J. Spatial and temporal patterns of ERK signaling during mouse embryogenesis.
Nakamura, H., Watanabe, Y. and Funahashi, J. Misexpression of the genes in the brain vesicles by in ovo electroporation.
Wakamatsu, Y., Watanabe, Y., Nakamura, H. and Kondoh, H. Regulation of the neural crest fate by N-myc: promotion of ventral migration and neuronal differentiation.
dev.biologists.org /cgi/content/full/131/17/4275   (6589 words)

  
 An Adenovirus Type 5 (Ad5) Amplicon-Based Packaging Cell Line for Production of High-Capacity Helper-Independent ...
E1, E2a, E3, and six of the seven E4 ORFs, with the exception of ORF3, were completely deleted from the vector backbone.
Generation of an adenovirus vector lacking E1, E2a, E3, and all of E4 except open reading frame 3.
Comparative analysis of the effects of packaging signal, transgene orientation, promoters, polyadenylation signals, and E3 region on growth properties of first-generation adenoviruses.
jvi.asm.org /cgi/content/full/79/10/6400   (6403 words)

  
 Arabidopsis NAC1 transduces auxin signal downstream of TIR1 to promote lateral root development -- Xie et al. 14 (23): ...
HFR1 is targeted by COP1 E3 ligase for post-translational proteolysis during phytochrome A signaling
Y. Jiao, H. Yang, L. Ma, N. Sun, H. Yu, T. Liu, Y. Gao, H. Gu, Z. Chen, M. Wada, M. Gerstein, H. Zhao, L.-J. Qu, and X. Deng
Y. Oono, C. Ooura, A. Rahman, E. Aspuria, K.-i.
www.genesdev.org /cgi/content/abstract/14/23/3024   (1599 words)

  
 Ninja Gainden? Special moves, throws? - Xbox 360 & Xbox Forums
So can someone give me advice on ways of fighting, cause all I am doing id smashing the X and Y buttons..
Humans Are the only things on earth that show malice toward other living things.
To damage him, wait until he is up against a wall, then run up it and push Y when you are near the top, you should come down and smash him pretty good.
forum.teamxbox.com /showthread.php?t=248629   (353 words)

  
 A Bayesian Analysis of Metazoan Mitochondrial Genome Arrangements -- Larget et al. 22 (3): 486 -- Molecular Biology and ...
Node Y now has a new permutation determined by its new location.
at Y the source and the permutation at A the target (p
Let y be the number of reversals on the path from
mbe.oxfordjournals.org /cgi/content/full/22/3/486   (5632 words)

  
 T-cell factors: turn-ons and turn-offs
Bhanot P, Brink M, Samos CH, Hsieh JC, Wang Y, Macke JP, Andrew D, Nathans J and Nusse R (1996) A new member of the frizzled family from Drosophila functions as a Wingless receptor.
Godde JS, Nakatani Y and Wolffe AP (1995) The amino-terminal tails of the core histones and the translational position of the TATA box determine TBP/TFIIA association with nucleosomal DNA.
Lorch Y, Cairns BR, Zhang M and Kornberg RD (1998) Activated RSC-nucleosome complex and persistently altered form of the nucleosome.
www.nature.com /emboj/journal/v21/n10/full/7594451a.html   (5701 words)

  
 Cloning and Sequencing of a Genomic Island Found in the Brazilian Purpuric Fever Clone of Haemophilus influenzae ...
clones E3 and F20 (40) were used to screen a genomic library,
E3 and F20 resulted in the isolation of the genomic clones pMU69
Cloning of the haemocin locus of Haemophilus influenzae type b and assessment of the role of haemocin in virulence.
iai.asm.org /cgi/content/full/73/4/1927   (7560 words)

  
 Histone deacetylase inhibitor LAQ824 down-regulates Her-2 and sensitizes human breast cancer cells to trastuzumab, ...
Xu, W., Mimnaugh, E., Rosser, F. N., Nicchitta, C., Marcu, M., Yarden, Y., and Neckers, L. Sensitivity of mature ErbB2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90.
Catley, L., Weisberg, E., Tai, Y. T., Lin, B., Mitsiades, N., Hideshima, T., LeBlanc, R., Shringapure, R., Burger, R., Mitsiades, C., Chauhan, D., Schlossman, R., Munshi, N., Richardson, P., and Griffin, J. LAQ824 is a novel histone deacetylase inhibitor with significant activity against multiple myeloma: results of a pre-clinical evaluation.
Boyes, J., Byfield, P., Nakatani, Y., and Ogryzko, V. Regulation of activity of the transcription factor GATA-1 by acetylation.
mct.aacrjournals.org /cgi/content/full/2/10/971   (7799 words)

  
 Genome Biology | Full text | Protein microarrays for highly parallel detection and quantitation of specific proteins ...
Patterson SD, Aebersold R: Mass spectrometric approaches for the identfication of gel-separated proteins.
Khan J, Bittner ML, Chen Y, Meltzer PS, Trent JM: DNA microarray technology: the anticipated impact on the study of human disease.
DeRisi J, Penland L, Brown PO, Bittner ML, Meltzer PS, Ray M, Chen Y, Su YA, Trent JM: Use of a cDNA microarray to analyse gene expression patterns in human cancer.
www.genomebiology.com /2001/2/2/research/0004   (5428 words)

  
 Targeted disruption of the Walker-Warburg syndrome gene Pomt1 in mouse results in embryonic lethality -- Willer et al. ...
B.P. is a Ciencia y Tecnología and Fondo de
Hayashi, Y. K., Ogawa, M., Tagawa, K., Noguchi, S., Ishihara, T., Nonaka, I. and Arahata, K. Neurology 57, 115–121.
Kim, D. S., Hayashi, Y. K., Matsumoto, H., Ogawa, M., Noguchi, S., Murakami, N., Sakuta, R., Mochizuki, M., Michele, D. E., Campbell, K. et al.
www.pnas.org /cgi/content/full/101/39/14126   (3923 words)

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