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Topic: 743


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  ET-743
Clinical pharmacology of the novel marine-derived anticancer agent Ecteinascidin 743 administered as a 1- and 3-h infusion in a phase I study.
Pharmacokinetics of ecteinascidin 743 administered as a 24-h continuous infusion to adult patients with soft tissue sarcomas: associations with clinical characteristics, pathophysiological variables and toxicity.
Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy.
liddyshriversarcomainitiative.org /Newsletters/V01N03/ET-743/et_743.htm   (3965 words)

  
 H.R. 743, Social Security Protection Act of 2003
H.R. 743 also proposes to extend the attorney-fee system temporarily to SSI, starting nine months after enactment and ending with agreements for representation that are signed five years later.
H.R. 743 clarifies that SSA would pay benefits from the trust fund and other costs--for the design, conduct, and evaluation of the demonstrations--from its appropriation for administrative expenses.
Under H.R. 743, SSA would split the first SSI check into at least two parts--one for the attorney and one for the beneficiary--as it does in DI.
www.cbo.gov /showdoc.cfm?index=4121&sequence=0   (3781 words)

  
 dw 743 - veilingkijker - nieuwe en tweedehands
nieuwe dewalt dw743n dw743 dw 743 afkort- en verstekzaag
a 743 eduard streltsov uit russische ploeg gezet
laatste zoekopdrachten: dw 743 rvs spaghetti spruitstuk lcd tv voliere cola kratten wintercollectie 2006 trio64 koya singer spoor marklin denison smock nescio stalen kast hembrug volvo v50 g3 honda mcx volvo v40 g3 kerstlampjes lasmasker pups husky
www.veilingkijker.nl /dw_743.html   (311 words)

  
 743 Rancimat for oils and fats (230 V) - Metrohm Ltd.   (Site not responding. Last check: 2007-11-03)
The 743 Rancimat as a modern, PC-controlled instrument allows the comfortable determination of the oxidation stability.
By using the 743 Rancimat it is possible to characterize the effectiveness of antioxidants.
The 743 Rancimat can also be used for the determination of the oxidation stability of foods containing fats.
products.metrohm.com /stability-measuring/rancimat/prod-27430014.aspx   (573 words)

  
 Fight Back / ¡Lucha y Resiste! Summer 2001 -- Teamster 743 Hacks Under Fire   (Site not responding. Last check: 2007-11-03)
This money was supposed to cover the health care costs of Local 743 members and their families.
The Local 743 Health and Welfare Fund was the health insurance for thousands of Teamsters working at dozens of workplaces.
Some workers could no longer afford their prescription drugs, some had to stop dental procedures before they were completed, and pregnant spouses were left wondering how they could ever pay for the upcoming delivery.
www.fightbacknews.org /2001summer/743hacks.htm   (811 words)

  
 Hurley Research Group Home Page
Ecteinascidin 743 (Et 743), a complex natural product produced by a marine tunicate (Rinehart et al., 1990), also seems to work by trapping DNA-binding proteins at sites where structural distortion of the DNA is recognized (Garcia-Nieto et al., 2000; Zewail- Foote et al., 2001).
Et 743 might also be analogous to topoisomerase poisons such as SN-38 because it has been reported to result in protein-associated strand breaks, probably involving NER (Takebayashi et al., 2001) (Figure 2e), although these strand breaks were not been observed in a subsequent study (Erba et al., 2001).
While Et 743 competes for binding of the transcriptional factor NF-Y to its cognate sequence in the transcriptional region of the MDR1 gene (Minuzzo et al., 2000), the concentrations required to do this are 103-fold higher than required to suppress MDR1 in cells.
www.pharmacy.arizona.edu /faculty/hurleylab/ecten.shtml   (686 words)

  
 ET-743: A Novel Agent with Activity in Soft Tissue Sarcomas -- Fayette et al. 10 (10): 827 -- The Oncologist
DNA sequence- and structure-selective alkylation of guanine N2 in the DNA minor groove by ecteinascidin 743, a potent antitumor compound from the Caribbean tunicate Ecteinascidia turbinata.
Ecteinascidin 743 induces protein-linked DNA breaks in human colon carcinoma HCT116 cells and is cytotoxic independently of topoisomerase I expression.
Pharmacokinetics of ecteinascidin 743 administered as a 24-h continuous intravenous infusion to adult patients with soft tissue sarcomas: associations with clinical characteristics, pathophysiological variables and toxicity.
theoncologist.alphamedpress.org /cgi/content/full/10/10/827   (2825 words)

  
 ecteinascidin 743
Cancer.gov Phase II Study of Ecteinascidin 743 in Pediatric Patients With Recurrent or Refractory Soft Tissue Sarcomas or Ewing's Sarcoma Family of Tumors.
Cancer.gov - Dictionary...ecteinascidin 743 An anticancer drug that inhibits the growth of cancer cells by disrupting the structure of tumor-cell DNA.
Center for Cancer Research - Staff Pages Ecteinascidin 743 (Et743) is a natural product (from a Caribbean marine tunicate) remarkably active against sarcomas and presently in phase I/II clinical trials...
www.cancer-help.org /cancer/0604/ecteinascidin_743.html   (333 words)

  
 743 Rancimat - Stability Measuring of Oils and Fats by - Metrohm Ltd.
743 Rancimat for determination of the oxidative stability
The 743 Rancimat is a modern, PC-controlled analytical instrument for the comfortable determination of the oxidation stability of oils and fats, also referred to as Oil Stability Index (OSI).
Instrument for the automatic determination of the oxidation stability of biodiesel with conductometric indication.
www.metrohm.com /products/08/743/743.html   (377 words)

  
 US 422/PA 743 Multiplex - Central PA/MD Roads
Barely after passing the eastern split, PA 743 splits off to the north on Park Avenue, while US 422 continues ahead on Chocolate Avenue to its western end.
PA 743 leads to the main attractions in Hershey, including the chocolate factory, the zoo, and the amusement park.
A PA 743 southbound view of the western split, near the middle of town.
www.m-plex.com /roads/pamplex/mp_us422_pa743.html   (122 words)

  
 Unique Features of the Mode of Action of ET-743 -- D'Incalci et al. 7 (3): 210 -- The Oncologist   (Site not responding. Last check: 2007-11-03)
Ecteinascidins 729, 743, 745, 759A, 759B, and 770: potent antitumor agents from the Caribbean tunicate Ecteinascidia turbinata.
Pharmacokinetics and pharmacodynamics of the novel marine-derived anticancer agent ecteinascidin 743 in a phase I dose-finding study.
Ecteinascidin 743 (ET-743) in ovarian cancer: activity in xenografts and preliminary results of an ongoing study in patients failing platinum-taxanes.
theoncologist.alphamedpress.org /cgi/content/full/7/3/210   (3558 words)

  
 Corgi Public Service (New Jersey) Yellow Coach 743 | ToyBusExpo.com
A Yellow Coach 743 in a grey Public Service Coordinated Transport of New Jersey trim released by Corgi in 1995.
Built by the Yellow Coach division of General Motors, the 743 was introduced in 1937 and revolutionized the bus industry.
It was the first mass produced coach with a rear mounted engine, a dedicated bus chassis and under-the-floor baggage compartments.
www.toybusexpo.com /diecast-bus/98_0_5_0_C   (227 words)

  
 Differential Rates of Reversibility of Ecteinascidin 743-DNA Covalent Adducts from Different Sequences Lead to ...
Ecteinascidin 743 (Et 743), one of a series of structurally related antitumor antibiotics isolated from a marine tunicate, is currently in phase II clinical trials.
Here, we report that the reaction of Et 743 with DNA is reversible under nondenaturing conditions and that the rate of this reverse reaction depends critically upon the DNA-modified sequence.
Consequently, it is the differences in the rate of the reverse reaction that dictate the sequence selectivity of Et 743 toward its favored target sequence.
pubs.acs.org /cgi-bin/abstract.cgi/jacsat/2001/123/i27/abs/ja004023p.html   (382 words)

  
 Overcoming Multidrug Drug Resistance in P-Glycoprotein/MDR1-overexpressing Cell Lines by Ecteinascidin 743 -- Kanzaki ...
Takebayashi, Y., Goldwasser, F., Urasaki, Y., Kohlhagen, G., and Pommier, Y. Ecteinascidin 743 induces protein-linked DNA breaks in human colon carcinoma HCT116 cells and is cytotoxic independently of topoisomerase I expression.
Pommier, Y., Kohlhagen, G., Bailly, C., Waring, M., Mazumder, A., and Kohn, K. DNA sequence- and structure-selective alkylation of guanine N2 in the DNA minor groove by ecteinascidin 743, a potent antitumor compound from the Caribbean tunicate Ecteinascidia turbinata.
Zewail-Foote, M., and Hurley, L. Ecteinascidin 743: a minor groove alkylator that bends DNA toward the major groove.
mct.aacrjournals.org /cgi/content/full/1/14/1327   (4217 words)

  
 A Phase I and Pharmacokinetic Study of Ecteinascidin-743 (Yondelis) in Children with Refractory Solid Tumors. A ...   (Site not responding. Last check: 2007-11-03)
Ecteinascidin 743, a novel natural cytotoxic compound, is potent for human neuroblastoma and rhabdomyosarcoma cell lines: multiple mechanisms of cell kill [abstract 4353].
A phase II and pharmacokinetic study of ecteinascidin 743 in patients with gastrointestinal stromal tumors.
Pharmaockinetics and pharmacodynamics of the novel marine-derived anticancer agent ecteinascidin 743 in a phase I dose-finding study.
clincancerres.aacrjournals.org /cgi/content/full/11/2/672   (3987 words)

  
 RFC 743 (rfc743) - FTP extension: XRSQ/XRCP
NWG/RFC# 743 KLH 30-Dec-77 08:39 42759 Network Working Group K. Harrenstien Request for Comments: 743 SRI-KL NIC: 42758 30 December 1977 FTP extension: XRSQ/XRCP This RFC describes an extension to FTP which allows the user of an ITS FTP server (i.e.
The first is that [Page 1] NWG/RFC# 743 KLH 30-Dec-77 08:39 42759 An Extension to FTP an XRSQ with no argument must always return a 200 reply and restore the default state of having no scheme selected.
By the way, I recommend RFC 691 as required reading for FTP implementors; maybe if enough people get together this mess can be straightened out.
www.faqs.org /rfcs/rfc743.html   (1984 words)

  
 Teamsters Local 743 - Unity, Pride and Strength
It is essential that the Local 743 office have your current mailing address.
Besides missing the Voice of 743, you'll be out of touch with your Union in many other ways.
Además de la falta de la Voz del 743, usted estará fuera de contacto con su Unión en otras numerosas maneras.
www.teamsters743.org   (337 words)

  
 Teamsters for a Democratic Union   (Site not responding. Last check: 2007-11-03)
The complaint in federal court states Local 743 officials, “denied members the right to vote when Defendant mailed members’ ballots to incorrect addresses, the ballots were marked by individuals other than the designated recipients, and the ballots were returned and counted in the election tally.”
Local 743 members were not surprised by the ruling.
It is time for justice for the 12,000 Teamsters in Local 743: the rightful winners of the election should be installed, and the Walston group removed.
www.tdu.org /HoffaWatch/NewHWhtml/DOLsayselectionrigged.htm   (336 words)

  
 ET-743 [Ecteinascidin 743] [Yondelis]
This suggests that ecteinascidin 743 is a novel DNA minor groove, guanine-specific alkylating agent.
Ecteinascidin 743 disorganizes the microtubule network as well.[7] Previous studies [in vitro and phase I] suggest potent cytotoxic activity of ET-743 in some mesenchymal tumors.
10.Ecteinascidin 743: a minor groove alkylator that bends DNA toward the major groove.
www.leiomyosarcoma.info /chemo49et.htm   (1513 words)

  
 Sequence-dependent Synergistic Cytotoxicity of Ecteinascidin-743 and Paclitaxel in Human Breast Cancer Cell Lines in ...
Ecteinascidin 743 (ET-743) is a potent antitumor agent from
Takabayashi Y., Pourquier P., Yoshida A., Kohlhagen G., Pommier Y. Poisoning of human DNA topoisomerase I by Ecteinascidin 743, an anticancer drug that selectively alkylates DNA in the minor groove.
Takebayashi Y., Goldwasser F., Urasaki Y., Kohlhagen G., Pommier Y. Ecteinascidin 743 induces protein-liked DNA breaks in human colon carcinoma HCT116 cells and is cytotoxic independently of topoisomerase I expression.
cancerres.aacrjournals.org /cgi/content/full/62/23/6909   (4083 words)

  
 PCI-X 743 StarFabric Accelerator Board   (Site not responding. Last check: 2007-11-03)
The PCI-X 743 StarFabric Accelerator Board executes fast point-to-point and cluster interconnections for Windows XP systems with a minimum of processor utilization.
The PCI-X 743 has a demonstrated capability of sustaining a point-to-point link at 290 Mbytes/s and a four-node cluster at 210 Mbytes/s with 3% or under host processor utilization.
The PCI-X 743 is delivered with driver support for Windows XP and Windows 2000.
www.cyclone.com /products/pci743.php   (596 words)

  
 Ecteinascidin-743 (ET-743) for Chemotherapy-Naive Patients With Advanced Soft Tissue Sarcomas: Multicenter Phase II and ...
Pommier Y, Kohlhagen G, Bailly C, et al: DNA sequence- and structure-selective alkylation of guanine N2 in the DNA minor groove by ecteinascidin 743, a potent antitumor compound from the Caribbean tunicate Ecteinascidia turbinata.
Van Kesteren C, Twelves C, Bowman A, et al: Clinical pharmacology of the novel marine-derived anticancer agent ecteinascidin 743 administered as a 1- and 3-h infusion in a phase I study.
Puchalski TA, Ryan DP, Garcia-Carbonero R, et al: Pharmacokinetics of ecteinascidin 743 administered as a 24-h continuous intravenous infusion to adult patients with soft tissue sarcomas: Associations with clinical characteristics, pathophysiological variables and toxicity.
www.jco.org /cgi/content/full/23/24/5484   (4999 words)

  
 Givenchy - Rouge Miroir - # 743 Luminous Brown - 3.5g - SHOP.COM
Givenchy - Rouge Miroir - # 743 Luminous Brown - 3.5g
Givenchy - Rouge Miroir - # 743 Luminous Brown - 3.5g - makeup / cosmetics Recommended Retail: US$21.00 All major brands - lowest prices on the net.
All other designated trademarks, copyrights and brands are the property of their respective owners.
www.shop.com /op/aprod-p12652198   (220 words)

  
 Transcriptional signature of Ecteinascidin 743 (Yondelis, Trabectedin) in human sarcoma cells explanted from ...
Transcriptional signature of Ecteinascidin 743 (Yondelis, Trabectedin) in human sarcoma cells explanted from chemo-naive patients -- Martínez et al.
Transcriptional signature of Ecteinascidin 743 (Yondelis, Trabectedin) in human sarcoma cells explanted from chemo-naïve patients
Ecteinascidin 743 (ET-743; Yondelis, Trabectedin) is a marine
mct.aacrjournals.org /cgi/content/full/4/5/814   (5089 words)

  
 Taiwan.743.B - Symantec.com   (Site not responding. Last check: 2007-11-03)
The virus is a direct infector, and it is 743 bytes long.
This means that when a file is infected, the size of the file is increased by 743 bytes.
Taiwan.743.B has a payload that is executed on 8th day of each month.
www.riptech.com /security_response/writeup.jsp?docid=2002-111219-0905-99   (122 words)

  
 eBay - 743 kodak, Digital Camera Accessories, Bags, Cases Straps items on eBay.com   (Site not responding. Last check: 2007-11-03)
Brand New Case for Kodak LS 755 743
WP-300 underwater case for Kodak LS 755 743 753 633
Underwater housing case for Kodak LS 755 743 753 633
search-desc.ebay.com /search/search.dll?query=743+kodak&newu=1&krd=1   (475 words)

  
 743 Rancimat for oils and fats (115 V) - Metrohm Ltd.   (Site not responding. Last check: 2007-11-03)
743 Rancimat for oils and fats (115 V) - Metrohm Ltd.
Products > Stability measuring instruments > Rancimat > 743 Rancimat for oils and fats (115 V)
743 Rancimat for oils and fats (115 V) 743 Rancimat for oils and fats (115 V)
products.metrohm.com /stability-measuring/rancimat/prod-27430015.aspx   (573 words)

  
 743 - Definition, explanation
ETA bombers each get 743 years in jail
Includes biography, photograph gallery, news, discography, album reviews, audio and video files, and message boards.
Recensione del film di Walter Salles con Gael Garcìa Bernal nel ruolo di Ernesto Guevara e Rodrigo de la Serna in quello di Alberto Granado.
www.calsky.com /lexikon/en/txt/7/74/743.php   (310 words)

  
 Telomere Dysfunction Increases Cisplatin and Ecteinascidin-743 Sensitivity of Melanoma Cells -- Biroccio et al. 63 (3): ...
Pommier Y, Kohlhagen G, Bailly C, Waring M, Mazumder A and Kohn KW (1996) DNA sequence- and structure-selective alkylation of guanine N2 in the DNA minor groove by ecteinascidin 743, a potent antitumor compound from the Caribbean tunicate Ecteinascidia turbinata.
Takebayashi Y, Goldwasser F, Urasaki Y, Kohlhagen G and Pommier Y (2001a) Ecteinascidin 743 induces protein-linked DNA breaks in human colon carcinoma HCT116 cells and is cytotoxic independently of topoisomerase I expression.
(2001b) Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair.
molpharm.aspetjournals.org /cgi/content/full/63/3/632   (4397 words)

  
 Christian Dior Cosmetic, Perfume/Fragrance, Christian Dior - Blush Final - No. 743 Natural Gold - 3.5g/0.12oz - makeup ...
Christian Dior - Blush Final - No. 743 Natural Gold - 3.5g/0.12oz - makeup / cosmetics
Christian Dior - Blush Final - No. 743 Natural Gold - 3.5g/0.12oz - makeup / cosmetics Free Shipping - worldwide.
This list may be very long, so the more specific you are, the easier it will be.
www.shanshanstyle.com /cosmetics.php?pid=02780980102   (340 words)

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