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	Aaron Ciechanover
		Aaron Ciechanover was born in 1947, in Haifa, Israel.
		Ciechanover is Professor at the Unit of Biochemistry and Director of the Rappaport Family Institute for Research in Medical Sciences at the Technion (Israel Institute of Technology) in Haifa, Israel.
		Hershko, A., Ciechanover, A., Heller, H., Haas, A. L., and Rose, I. (1980) Proposed role of ATP in protein breakdown: conjugation of proteins with multiple chains of the polypeptide of ATP - dependent proteolysis.
	www.jewishvirtuallibrary.org /jsource/biography/Ciechanover.html (366 words)

	Aaron Ciechanover - Wikipedia, the free encyclopedia
		Aaron Ciechanover (אהרון צ'חנובר) (born October 1, 1947) is an Israeli biologist with Polish-Jewish roots.
		Hershko, A., Ciechanover, A., and Rose, I.A. (1979) "Resolution of the ATP-dependent proteolytic system from reticulocytes: A component that interacts with ATP".
		Hershko, A., Ciechanover, A., Heller, H., Haas, A.L., and Rose I.A. (1980) "Proposed role of ATP in protein breakdown: Conjugation of proteins with multiple chains of the polypeptide of ATP-dependent proteolysis".
	en.wikipedia.org /wiki/Aaron_Ciechanover (237 words)

	Ciechanover, Aaron - MSN Encarta
		Ciechanover, Aaron, born in 1947, Israeli biochemist and cowinner of the 2004 Nobel Prize in chemistry for his part in discovering an important regulatory system by which cells label certain proteins for destruction.
		Ciechanover and his fellow Nobel laureates Avram Hershko of Israel and Irwin Rose of the United States originally made their discoveries in the late 1970s and early 1980s.
		As a graduate student in the 1970s, Ciechanover was working under the guidance of Hershko on a relatively neglected area of cellular research: the breakdown of proteins inside cells.
	ca.encarta.msn.com /encyclopedia_701711815/Ciechanover_Aaron.html (654 words)

	History Channel Search Results
		The discoveries made by Ciechanover and his colleagues paved the way for researchers to begin developing therapeutic drugs targeting aspects of the ubiquitin system.
		Ciechanover, Hershko, and Rose each were awarded a one-third share of the 2004
		Ciechanover and Hershko, in recognition of their work on the ubiquitin-mediated protein degradation system, received the Albert Lasker Basic Medical Research Award in 2000.
	www.historychannel.com /encyclopedia/article.jsp?link=FWNE.fw..ci141950.a (367 words)

	The Lasker Foundation \| Former Award Winners, Basic Medical Research 2000
		Dr. Ciechanover was born in 1947, in Haifa, Israel.
		Ciechanover, A., Finley, D. and Varshavsky, A. (1984) Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85.
		Hershko, A., Ciechanover, A., Heller, H., Haas, A. L., and Rose, I. (1980) Proposed role of ATP in protein breakdown: conjugation of proteins with multiple chains of the polypeptide of ATP-dependent proteolysis.
	www.laskerfoundation.org /awards/library/2000basic_info.shtml (1087 words)

	Israel21c
		Aaron Ciechanover, 57, Avram Hershko, 67 - the first Israelis to win the chemistry prize - and Irwin Rose, 78, were honored by the Royal Swedish Academy of Sciences for their work in the 1980s that discovered one of the cell's most important cyclical processes, regulated protein degradation.
		Ciechanover is director of the Rappaport Family Institute for Research in Medical Sciences at the Technion in Haifa, while Hershko, originally from Hungary, is a professor at the institute.
		Ciechanover began studying medicine at the Hebrew University of Jerusalem in 1965 within the framework of his military service and from 1973-76 served as a combat physician and later in medical research.
	www.israel21c.org /bin/en.jsp?enPage=BlankPage&enDisplay=view&enDispWhat=object&enDispWho=Articles^l799&enZone=Health&enVersion=0& (1282 words)

	Record Article (Site not responding. Last check: 2007-10-30)
		Aaron J. Ciechanover, M.D., D.Sc., a visiting professor of pediatrics at the School of Medicine since 1987, received the 2000 Albert Lasker Basic Medical Research Award Sept. 22 in New York.
		Ciechanover, who also is director of the Rappaport Family Institute for Research in the Medical Sciences and professor of biochemistry at the Technion-Israel Institute of Technology, shares the award with two other scientists.
		Ciechanover has received numerous other honors, including a research career development award from the Israel Cancer Research Fund from 1985 to 1990, the Henry Taub Prize for Excellence in Research in 1997 and the Ilse and Helmut Wachter Prize of Austria in 1999.
	record.wustl.edu /archive/2000/09-29-00/articles/aaron.html (367 words)

	Record: Nobel Prize shared by visiting medical professor Ciechanover
		Aaron Ciechanover, M.D., D.Sc., visiting professor of pediatrics and the Research Distinguished Professor of Biochemistry at Technion-Israel Institute of Technology in Haifa, Israel, was selected Oct. 6 to receive the 2004 Nobel Prize in chemistry.
		Ciechanover's association with the University began with a two-year sabbatical during which he worked with Alan Schwartz, Ph.D., M.D., the Harriet B. Spoehrer Professor and head of the Department of Pediatrics.
		Ciechanover earned a medical degree from Hadassah Medical School in Israel and was a graduate student in biochemistry with Hershko in Haifa.
	record.wustl.edu /news/page/normal/3995.html?at (516 words)

	Amazon.de: Protein Degradation 1. Ubiquitin and the Chemistry of Life: Bücher (Site not responding. Last check: 2007-10-30)
		Aaron Ciechanover is one of the editors of this series, and Avram Hershko has contributed to the opening chapter of the present volume.
		Aaron Ciechanover obtained his MD from the Hebrew University in Jerusalem (Israel), and his PhD from the Technion-Israel Institute of Technology in Haifa, where he is presently serving as Professor of Biochemistry.
		Professor Ciechanover is known for his discovery of the first ubiquitin system mutant cell, demonstrating the role of the ubiquitin-proteasome proteolytic system in protein degradation in vivo.
	www.amazon.de /exec/obidos/tg/stores/detail/-/books/3527308377/reviews (790 words)

	CIECHANOVER, AARON - CIRS
		Ryoo HD, Bergmann A, Gonen H, Ciechanover A, Steller H. Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1.,
		Amir RE, Iwai K, Ciechanover A. The NEDD8 pathway is essential for SCF(beta -TrCP)-mediated ubiquitination and processing of the NF-kappa B precursor p105.,
		Glickman MH, Ciechanover A. The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction.,
	www.cirs.net /researchers/researchers.php?id=662 (219 words)

	EJP \| News \| Eastern Europe \| Chemist Entertains Berlin Audience
		Together with dozens of Nobel Prize laureates, Aaron Ciechanover was on a visit to Berlin, in honour of the 100-year anniversary of the publication of Albert Einstein’s “Theory of Relativity”.
		Ciechanover is a professor at Haifa’s Technion in the department of biomedicine.
		Ciechanover won the 2004 Nobel Prize for Chemistry for research he did over 25 years ago.
	www.ejpress.org /article/news/eastern_europe/1756 (447 words)

	protein degradation (Site not responding. Last check: 2007-10-30)
		Through their discovery of this protein-regulating system Aaron Ciechanover, Avram Hershko and Irwin Rose have made it possible to understand at molecular level how the cell controls a number of very important biochemical processes such as the cell cycle, DNA repair, gene transcription and quality control of newly-produced proteins.
		Using such an extract Aaron Ciechanover, Avram Hershko and Irwin Rose, in a series of epoch-making biochemical studies in the late 1970s and early 1980s, succeeded in showing that protein degradation in cells takes place in a series of step-wise reactions that result in the proteins to be destroyed being labeled with the polypeptide ubiquitin.
		In their attempts to remove the hemoglobin using chromatography, Aaron Ciechanover and Avram Hershko discovered that the extract could be divided into two fractions, each inactive on its own.
	sps.k12.ar.us /massengale/protein_degradation.htm (2680 words)

	University biochemist wins Nobel Prize - News
		Aaron Ciechanover, a visiting professor at Washington University's School of Medicine, was awarded the 2004 Nobel Prize in Chemistry on Wednesday.
		Ciechanover, Hershko and Rose won the prize for research they started in the late 1970s and early 1980s on how cells regulate the breakdown of unwanted proteins.
		Ciechanover is the 23rd Nobel Laureate associated with the University.
	www.studlife.com /news/2004/10/08/News/University.Biochemist.Wins.Nobel.Prize-747533.shtml (551 words)

	Professor Avram Hershko, Professor Aaron Ciechanover
		Professors Aaron Ciechanover (1947-) and Avram Hershko (1937-) share the 2004 Nobel Prize for Chemistry with Professor Irwin Rose (USA) for contributing "ground-breaking knowledge" in "discoveries of ubiquitin-related protein degeneration" (The "Ubiquitin System"), identifying the staged process in cells to be marked for destruction - as published in 1978 and pursued in the 1980s.
		The period in which they worked together was from 1977-1981, while Aaron Ciechanover was studying for his Ph.D. under Professor Hershko, which he received in 1981-2.
		Professor Ciechanover was born in Haifa in 1947 to an immigrant family from Poland and lost his parents during his school years.
	www.jafi.org.il /education/actual/nobel.html (606 words)

	Pittsburgh - ISRAEL21c: Two Israelis and An American Win Nobel Prize in Chemistry
		Aaron Ciechanover, 57, Avram Hershko, 67 - the first Israelis to win the chemistry prize - and Irwin Rose, 78, were honored by the Royal Swedish Academy of Sciences for their 1980s that discovery of regulated protein degradation in body cells.
		Hershko and Ciechanover began working on their research into the ubiquitin system in 1981, when Hershko oversaw Ciechanover's doctoral thesis in science at the medical school of the Technion.
		Ciechanover was born in Haifa in 1947 to parents who immigrated from Poland before World War II.
	www.ujf.net /content_display.html?ArticleID=127836 (1127 words)

	Lifestyles Magazine (Site not responding. Last check: 2007-10-30)
		Credited along with Aaron Ciechanover and Irwin Rose with the discovery of the mechanism responsible for protein degradation in the body, Hershko relates that researchers whose efforts have led to scientific breakthroughs often suffer from "October Syndrome"-sitting at home and waiting for the
		Ciechanover was born in Haifa, was orphaned as a youngster and grew up with his aunt.
		Ciechanover repeats God's name over and over during his explanation, as he talks about how amazing the human body is. I ask Hershko if the discovery brought him closer to philosophical thoughts about God.
	www.lifestylesmagazine.com /Lifestyle_01-2005_004.html (2352 words)

	Press Release: The Nobel Prize in Chemistry 2004
		Aaron Ciechanover, Avram Hershko and Irwin Rose went against the stream and at the beginning of the 1980s discovered one of the cell's most important cyclical processes, regulated protein degradation.
		Aaron Ciechanover, Avram Hershko and Irwin Rose have brought us to realise that the cell functions as a highly-efficient checking station where proteins are built up and broken down at a furious rate.
		The degradation is not indiscriminate but takes place through a process that is controlled in detail so that the proteins to be broken down at any given moment are given a molecular label, a ‘kiss of death', to be dramatic.
	uk.geocities.com /chemystry111_rer/press.html (588 words)

	Engineering News - Spring 2005
		Aaron Ciechanover, the 2004 Nobel Laureate in Chemistry, discussed his research on protein degradation to an audience of more than 300 students, faculty and invited guests at a special lecture sponsored by the School.
		Ciechanover, of the Faculty of Medicine at the Cancer and Vascular Biology Research Center of Technion-Israel Institute of Technology in Haifa, shared last year’s Nobel prize in Chemistry for discovering how the cell controls processes by breaking down certain proteins and not others.
		Ciechanover’s work shows that proteins are targeted to be destroyed by the molecule ubiquitin.
	www.engineering.columbia.edu /news/spring05/ciechanover.php (278 words)

	Aaron Ciechanover - Search Results - MSN Encarta (Site not responding. Last check: 2007-10-30)
		Ciechanover, Aaron, born in 1947, Israeli biochemist and cowinner of the 2004 Nobel Prize in chemistry for his part in discovering an important...
		Aaron, first Jewish high priest and traditional founder of the Hebrew priesthood.
		According to the Old Testament Book of Exodus, Aaron was the older...
	encarta.msn.com /encnet/refpages/search.aspx?q=Aaron+Ciechanover (88 words)

	BioSpectrumIndia - the business of biotech - BioShakers
		The Royal Swedish Academy of Sciences awarded the Nobel Prize in Chemistry for 2004 "for the discovery of ubiquitin-mediated protein degradation" jointly to Aaron Ciechanover and Avram Hershko from the Technion, Israel Institute of Technology, Haifa, and Irwin Rose from the University of California, Irvine, USA.
		Currently a professor in the unit of biochemistry, Aaron Ciechanover is also the director of the Rappaport Family Institute for Research in Medical Sciences at the Technion (Israel Institute of Technology) in Haifa, Israel.
		Ciechanover became a professor at the Technion in 1992 and was an associate professor there from 1987 to 1992.
	www.biospectrumindia.com /content/shakers/10411041.asp (3300 words)

	Nobel Prize awarded to Washington University visiting professor
		Oct. 6, 2004 -- Aaron Ciechanover, M.D., D.Sc., visiting professor of pediatrics at Washington University School of Medicine in St. Louis and Research Distinguished Professor of Biochemistry at Technion-Israel Institute of Technology, Haifa, Israel, today was selected Oct. 6 to receive the 2004 Nobel Prize in Chemistry.
		Ciechanover has been a visiting professor at Washington University since 1987, spending a portion of each year in the School of Medicine's Department of Pediatrics.
		Ciechanover's association with the University began with a two-year sabbatical during which he worked with Alan Schwartz, M.D., Ph.D., Harriet B. Spoehrer Professor and head of the Department of Pediatrics and professor of molecular biology and pharmacology at the School of Medicine and pediatrician-in-chief at St. Louis Children's Hospital.
	news-info.wustl.edu /news/page/normal/3996.html (528 words)

	Apria - resources - News (Site not responding. Last check: 2007-10-30)
		Ciechanover has reported on these investigations at the PCF's annual Scientific Retreat and is scheduled to update these reports at the next Retreat later this month.
		The Nobel Foundation recognized Dr. Ciechanover's work in illuminating the significance of the cellular machine called the proteasome, which regulates the destruction of unneeded cell proteins.
		"The PCF funded Dr. Ciechanover through its Israel Initiative, which is part of our worldwide effort to harness the talents of the best and brightest in the fight for better treatments and a cure for recurrent prostate cancer," he added.
	www.apria.com /resources/1,2725,494-218314,00.html (324 words)

	Today@UCI: UCI In The News:
		Ciechanover is director of the Rappaport Family Institute for Research in Medical Sciences at the Technion, in Haifa, Israel, while Mr.
		UCI MENTIONED: The winners are Dr. Aaron Ciechanover, 57, and Dr. Avram Hershko, 67, both professors of biochemistry at the Technion-Israel Institute of Technology in Haifa, and Dr. Irwin A. Rose, 78, a scientist at the University of California, Irvine.
		UCI MENTIONED: Aaron Ciechanover and Avram Hershko of the Israel Institute of Technology, together with Irwin Rose of the University of California at Irvine, received the honor “for the discovery of ubiquitin-mediated protein degradation,” according to the selection committee.
	today.uci.edu /news/uciinthenews_041007.asp (2617 words)

	IFMBE News: November 2004 (Site not responding. Last check: 2007-10-30)
		These have numerous important functions: as accelerators of chemical reactions in the form of enzymes, as signal substances in the form of hormones, as important actors in the immune defence and by being responsible for the cell's form and structure.
		Much of the work was done during a series of sabbatical leaves that Avram Hershko and Aaron Ciechanover of Haifa University spent with Irwin Rose at the Fox Chase Cancer Center in Philadelphia, USA.
		In their attempts to remove the haemoglobin using chromatography, Aaron Ciechanover and Avram Hershko discovered that the extract could be divided into two fractions, each inactive on its own.
	ifmbe-news.iee.org /ifmbe-news/nov2004/nobelchem.html (2557 words)

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