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Topic: AbioCor

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Artificial heart

	AbioCor - Wikipedia, the free encyclopedia
		AbioCor is an artificial heart developed by the Massachusetts-based company AbioMed.
		The AbioCor runs on a rechargeable source of power and is being tested in clinical trials in preparation for approval by the Food and Drug Administration.
		For a patient to be eligible for implantation with the AbioCor, the person must have severe heart failure (with failure of both ventricles) and must be likely to die within two weeks without transplantation.
	en.wikipedia.org /wiki/AbioCor (183 words)

	AbioCor FAQ: Beth Israel Deaconess Medical Center - Boston, Hospital, abiocor, heart, artificial heart
		The AbioCor is intended to replace the severely damaged natural heart and serve as an alternative to heart transplantation - the current method of saving patients with failing natural hearts.
		The AbioCor is intended for use with patients who suffer from biventricular heart failure and for whom existing methods of surgical intervention or drug therapy are inadequate.
		Equipped with an internal motor, the AbioCor is able to pump blood through the lungs and to the rest of the body, with a pulsatile flow that mimics the natural heart.
	www.bidmc.harvard.edu /display.asp?leaf_id=6730 (1198 words)

	AbioCor Implantable Replacement Heart - Texas Heart Institute - Heart Assist Devices
		The AbioCor is designed to sustain the body's circulatory system and to extend the lives of patients who would otherwise die of heart failure.
		Unlike the artificial hearts of the past, patients are not tethered to a large, air-pumping console nor do they have wires or tubes piercing their skin.
		The AbioCor is intended for use in end-stage heart failure patients whose hearts have irreversible left and right ventricular failure and for whom surgery or medical therapy is inadequate.
	www.bcm.edu /tmc/thi/abiocor.html (591 words)

	The Implantable Artificial Heart Project
		The AbioCor™ Implantable Replacement Heart is an advanced medical system being developed by ABIOMED Inc., in order to extend and improve the lives of patients who would otherwise die of heart failure.
		The AbioCor is intended for use with patients whose hearts have irreparably damaged left and/or right ventricles, and for whom existing methods of surgical intervention and/or drug therapy are inadequate.
		Equipped with an internal motor, the AbioCor is able to move blood through the lungs and to the rest of the body, simulating the rhythm of a heartbeat.
	www.heartpioneers.com /abiocorfaq.html (705 words)

	CHFpatients.com - Artificial Hearts
		I'll be focusing on Abiomed's Abiocor TAH for now, because it is in phase one safety trials in end-stage heart failure patients in the USA.
		The Abiocor TAH is made mainly of titanium and a kind of polyurethane plastic called Angioflex.
		The AbioCor is meant to help patients at risk of imminent death, who cannot for some reason get a heart transplant, and cannot be helped by other available treatments.
	www.chfpatients.com /implants/artificial_hearts.htm (2704 words)

	Society of Cardiovascular Anesthesiologists
		The AbioCor™ heart is made of titanium and Angioflex™, a proprietary polyurethane plastic that is durable and non-thrombogenic.
		The operation that implants the AbioCor™ heart consists of intraabdominal placement of the internal controller, internal battery, and the TET coil, institution of cardiopulmonary bypass, and then orthotopic implantation of the thoracic unit.
		The patient who received the first AbioCor™ heart in July exceeded the original life expectancy and was reported to be walking and eating on his own on August 2.
	www.scahq.org /sca3/newsletters/2001oct/park.shtml (1354 words)

	World’s Third Recipient of AbioCor Artificial Heart is Born Risk Taker, Continues Steady Recovery - Texas Heart ...
		AbioCor recipient Bobby Harrison meets the press with his wife Doris by his side.
		As with all patients in the the AbioCor clinical study, Mr.
		The AbioCor is an engineering achievement, according to O.H. Frazier, MD, chief of Cardiopulmonary Transplantation and director of Surgical Research at the Texas Heart Institute, and chief of Transplant Service at St. Luke's Episcopal Hospital.
	www.tmc.edu /thi/abio1_02.html (900 words)

	The Bionic Man has a Heart
		The AbioCor Implantable Replacement Heart is designed for patients whose hearts have suffered irreparable damage to both ventricles.
		When these patients are at risk of death, the AbioCor is designed to both extend life and provide a reasonable quality of life.
		The AbioCor Heart is made from titanium metal and a special type of plastic.
	eduspace.free.fr /vs_pages/bionic_heart.htm (641 words)

	FDA panel weighs artificial-heart implants (Site not responding. Last check: 2007-10-29)
		The AbioCor II, which is smaller and could be used by women as well as men, is under development.
		The AbioCor will be largely used by people with severe heart failure as a permanent replacement, though the company sees possible temporary uses by patients who have to wait a long time for a transplant.
		The AbioCor, which uses both an internal and an external battery, is one of several devices in the pipeline of a new breed of treatments called "destination therapy." These products are meant to provide permanent, lifetime support to patients' hearts and are the latest trend in the field.
	www.post-gazette.com /pg/05168/523353.stm (932 words)

	Support Withdrawn for Twelfth AbioCor® Patient
		This decision was made as a result of unrecoverable liver and kidney failure, conditions that pre-dated the AbioCor implant.
		Candidates for the clinical trial must suffer from biventricular heart failure, be ineligible for heart transplantation and not able to be helped by any other available therapy, and have a high probability of dying in less than 30 days.
		The AbioCor has not been approved for commercial distribution, and is not available for use or sale outside of the initial clinical trial.
	www.bcm.edu /tmc/thi/abiocor-5-04.html (442 words)

	TIME.com: Inventions of the Year -- The best inventions of 2001
		Unlike the first generation of artificial hearts—which were attached by tubes and wires to refrigerator-size p units—the softball-size, plastic-and-titanium AbioCor is entirely self-contained, save for a wireless battery pack strapped to the waist.
		AbioCor's manufacturer, a company called Abiomed, based in Danvers, Mass., decided in advance that the operation would be deemed a success if the patient didn't die within 60 days.
		Abiomed is working on a new, smaller AbioCor, for women and men with small chest cavities.
	www.time.com /time/2001/inventions/health (408 words)

	CNN.com - Patient gets first totally implanted artificial heart - July 3, 2001
		The AbioCor is a totally implantable artificial heart made of titanium and plastic.
		The AbioCor is designed for heart failure patients who have failed all existing therapies.
		The AbioCor is designed to move blood through the lungs and to the rest of the body, simulating the rhythm of a heartbeat.
	archives.cnn.com /2001/HEALTH/conditions/07/03/artificial.heart (821 words)

	A significant technical advance First self-contained mechanical heart implanted in the US
		The bleeding was due to anti-coagulant drugs administered to the patient in order to prevent the formation of blood clots inside the heart—a known danger that has occurred with other artificial heart devices.
		The AbioCor unit was then connected to the patient’s blood vessels using special vessel grafts.
		The AbioCor’s development was assisted by legislation passed in 1988, requiring the US National Heart, Lung and Blood Institute (NHLBI) to award $US22.6 million to four contractors (including Abiomed) to build an artificial heart.
	www.wsws.org /articles/2001/aug2001/hear-a06.shtml (1697 words)

	Beat Goes On For Artificial Heart, Second AbioCor Implant In A Month At Louisville Hospital - CBS News
		That surgery was the first AbioCor implant performed by Gray and Dowling since January 2003.
		Another patient received an AbioCor in a surgery Feb. 20 at the Texas Heart Institute at St. Luke's Episcopal Hospital in Houston.
		The softball-sized AbioCor is powered by batteries and made of plastic and titanium.
	uttm.com /stories/2004/01/16/health/main593697.shtml (562 words)

	Abiomed to slow rate of enrollment in AbioCor clinical trial to address some adverse events in some patients. \| Health ...
		Abiomed, Inc., Danvers, MA, announced it is slowing the rate of patient enrollment in the clinical trial of its AbioCor Implantable Replacement Heart in order to address adverse neurological events sustained by some recipients of the device.
		The company says the rescheduled rate of patient enrollment for the 9 remaining AbioCor implants in the trial means it does not expect to meet its previous target date of June 30.
		Of the 6 patients implanted with an AbioCor, 4 have died since clinical trials began in July 2001.
	www.allbusiness.com /periodicals/article/175175-1.html (558 words)

	Artificial Heart Still Beating - CBS News
		The AbioCor artificial heart is a softball-sized titanium and plastic pump.
		Surgery involves implantation of the artificial heart, an electrical coil used to keep the internal battery charged and a battery and controller that regulates the heart's rate.
		The AbioCor is considered a technological leap from the mechanical hearts used in the 1980s, such as the Jarvik-7.
	www.cbsnews.com /stories/2002/09/12/earlyshow/health/main521865.shtml (833 words)

	FDA expert panel to review Abiomed's artificial heart (Site not responding. Last check: 2007-10-29)
		The technology behind the AbioCor artificial heart is the result of over 20 years of design, research, and testing conducted by Abiomed, Inc. and its collaborators, with the support of the National Heart, Lung and Blood Institute.
		The AbioCor is driven by a high-precision electro-hydraulic system pumping seamlessly to drive consistent and stable circulation, similar to a patient's natural heart.
		The AbioCor 2 is currently being implanted in animal studies and has the potential to last longer with a 35 percent reduction in size.
	www.news-medical.net /?id=9385 (733 words)

	AbioCor Implantable Replacement Heart - Texas Heart Institute - Heart Assist Devices
		Its unique design allows it to be totally implanted within the body.
		Are not eligible for a natural heart transplant.
		Power to the AbioCor is achieved with an energy-transfer device called a transcutaneous energy transmission (TET) system.
	texasheart.org /Research/Devices/abiocor.cfm (591 words)

	Man with artificial AbioCor heart dies
		The patient, 73-year-old William Wiley of Glasgow, received the AbioCor artificial heart in a May 24 surgery at the Louisville hospital.
		Wiley was the 14th recipient of the softball-sized pump made of plastic and titanium and powered by batteries.
		The 13th AbioCor recipient died in September, also at Jewish Hospital, of an unspecified malfunction in the device, AbioMed said at the time.
	www.enquirer.com /editions/2004/11/06/loc_kyartificialheart.html (225 words)

	IndustryWeek : Technologies Of The Year -- AbioCor Implantable Replacement Heart
		Although other mechanical hearts have been developed and implanted in humans, the AbioCor is the first that can function without the user being permanently attached to a power source via skin-piercing wires or tubes.
		The AbioCor has a centrifugal-force motor at its center, which is surrounded by a siliconized fluid.
		Once the AbioCor is implanted, it is powered by four pounds of batteries that the patient wears on a belt.
	www.industryweek.com /ReadArticle.aspx?ArticleID=990 (1009 words)

	The AbioCor Replacement Heart - A Change of Heart: Surgery (Site not responding. Last check: 2007-10-29)
		To implant the AbioCor, the surgical team first positions the energy transfer coil in the patient's abdomen.
		Atrial cuffs are sewn to the patient's right and left atria and grafts are attached to the aorta and pulmonary artery.
		The AbioCor is positioned in the chest cavity and four quick snaps on the AbioCor are used to connect it to the grafts on the right and left atria, aorta and pulmonary artery.
	www.mos.org /cst-archive/article/3737/3.html (143 words)

	Howstuffworks "How Artificial Hearts Work"
		The AbioCor is the first artificial heart to be used in nearly two decades.
		On July 2, 2001, heart failure patients were given new hope as surgeons at Jewish Hospital in Louisville, Kentucky, performed the first artificial heart transplant in nearly two decades.
		The AbioCor Implantable Replacement Heart is the first completely self-contained artificial heart and is expected to at least double the life expectancy of heart patients.
	www.howstuffworks.com /artificial-heart.htm (231 words)

	artificial heart
		In 2001, however, a second type of artificial heart, the AbioCor, was implanted in several patients.
		Unlike the Jarvik-7, the AbioCor is powered by electrical energy that is transmitted from a battery across the skin to an internal coil and backup battery.
		Because an opening in the skin is not needed to allow passage for tubes or wires, the risk of infection is greatly reduced.
	www.factmonster.com /ce6/sci/A0823119.html (376 words)

	TIME.com: Reviving Artificial Hearts -- Page 1
		The AbioCor heart, manufactured by Massachusetts medical company Abiomed, is a grapefruit-sized unit that is wholly contained within the chest cavity, with power transmitted to it via a radio transmitter.
		The AbioCor, and a similar next-generation heart, the Jarvik 2000, aren't ready to act as a full-time substitute.
		Designers have also found ingenious ways to have their hearts do the actual pumping: the AbioCor is essentially a sphere within a sphere, with the inner ball scuttling back and forth.
	www.time.com /time/health/article/0,8599,166327,00.html (844 words)

	Abiomed awarded ISO certification from Great Britain for AbioCor implantable replacement heart. \| Health Care Industry (Site not responding. Last check: 2007-10-29)
		Abiomed, Inc., Danvers, MA, announced that its AbioCor replacement heart design, development and manufacturing operations in Danvers have been awarded ISO 9001 and EN46001 certification by the British Standards Institute (BSI).
		Before the company can sell the AbioCor within the European community, Abiomed must attain the CE mark, which allows the device to be commercially distributed to all member countries of the European Union.
		Abiomed to slow rate of enrollment in AbioCor clinical trial to address some adverse events in some patients.
	www.allbusiness.com /periodicals/article/129121-1.html (459 words)

	Newsmaker Interview: Artificial Heart, Page 2
		In the first section of this interview we discuss the early days and current status of LVADs, left ventricular assist devices that are implanted to assist the weakened hearts of patients with heart failure.
		In the following section we discuss Abiocor, a new artificial heart that is now ready for human trials.
		So it is important the Abiocor be used and become a mature, patient friendly system.
	www.accessexcellence.org /WN/NM/ozpage2.html (1349 words)

	Heart Replacement (Site not responding. Last check: 2007-10-29)
		Two decades later, only two remained: ABIOMED, with the AbioCor Implantable Replacement Heart, and Penn State, with the Penn State Heart.
		The AbioCor II is smaller, and therefore able to fit significantly more of the adult population, and is being designed with the goal of five-year reliability.
		The Company intends to submit for an Investigational Device Exemption in 2006 in order to begin clinical trials, with a goal of seeking premarket approval by 2008.
	www.abiomed.com /products/heart_replacement/index.cfm (237 words)

	The AbioCor Replacement Heart (Site not responding. Last check: 2007-10-29)
		Many of the prototypes, however, suffered from setbacks like malfunctioning valves, unwieldly power sources and protruding tubes and wires.
		The combination of advances in miniaturization, biosensors, plastics and energy transfer, makes the AbioCor fully implantable.
		The AbioCor is currently enrolled in clinical trials.
	www.mos.org /cst-archive/article/3737 (110 words)

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