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Topic: Acceptable Daily Intake

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	University of Miami School of Medicine - Glossary - Acceptable daily intake
		Acceptable daily intake: Estimate of the amount of a substance in food or drinking water, expressed on a body mass basis (usually mg/kg body weight), which can be ingested daily over a lifetime by humans without appreciable health risk.
		For calculation of the daily intake per person, a standard body mass of 60 kg is used.
		The acceptable daily intake is normally used for food additives (tolerable daily intake is used for contaminants).
	www.med.miami.edu /glossary/art.asp?articlekey=30760 (95 words)

	045. Introduction (FAO Meeting Report PL/1965/10/2)
		Acceptable daily intake: The daily dosage of a chemical which, during an entire lifetime, appears to be without appreciable risk on the basis of all the facts known at the time.
		Knowledge of the "acceptable daily intakes" of these substances would be useful in assessing consumer hazards that might arise from the use of the fumigant, particularly under conditions of abnormal pest infestation when the dose might have to be increased or the treatment repeated.
		The acceptable daily intake figures in the monographs that follow are intended to be of value as a check to ensure that tolerances are toxicologically acceptable.
	www.inchem.org /documents/jmpr/jmpmono/v65apr01.htm (4213 words)

	353. Annexes 2 & 3 (WHO Pesticide Residues Series 5)
		Temporary acceptable daily intake A temporary acceptable daily intake is an acceptable daily intake established for a specified, limited period.
		Conditional acceptable daily intake A conditional acceptable daily intake is one that is established for a pesticide in order to limit its use to those situations where no satisfactory substitutes are available.
		Potential daily intake The potential daily intake of a pesticide is the theoretical intake calculated on the basis of the maximum residue limits and/or extraneous residue limits and the per caput consumption of the relevant food commodities per day.
	www.inchem.org /documents/jmpr/jmpmono/v075pr40.htm (2657 words)

	204. Appendix III (AGP:1970/M/12/1)
		ACCEPTABLE DAILY INTAKE The acceptable daily intake of a chemical is the daily intake which, during an entire lifetime, appears to be without appreciable risk on the basis of all the known facts at the time.
		CONDITIONAL ACCEPTABLE DAILY INTAKE A conditional acceptable daily intake is one which is established for a pesticide in order to limit its use to those situations where no satisfactory substitutes are available.
		TENTATIVE NEGLIGIBLE DAILY INTAKE A tentative negligible daily intake is allocated to a pesticide when unintentional residues of it occur in food and for which at least a short term toxicity study is available.
	www.inchem.org /documents/jmpr/jmpmono/v070pr27.htm (1880 words)

	GLOSSARY OF TERMS ON CHEMICAL SAFETY - International occupational safety & health information centre
		The daily intake may be expressed as the amount taken in by a particular exposure route, e.g., ingestion or inhalation.
		The daily intake from food is the total amount of a given substance taken in during one day through the consumption of food.
		The daily intake by inhalation is calculated by multiplying the concentration of the substance (or agent) in air by the total amount of air inhaled during one day (24 hours).
	www.ilo.org /public/english/protection/safework/cis/products/safetytm/glossary.htm (14511 words)

	[No title] (Site not responding. Last check: 2007-10-20)
		ISO, 1972 absorption coefficient (in biology) Ratio of the absorbed amount (uptake) of a substance to the administered amount (intake): for exposure by way of the respiratory tract, the coefficient is the ratio of the absorbed amount to the amount of the substance (usually particles) deposited (adsorbed) in the lungs.
		acceptable daily intake (ADI) Estimate of the amount of a substance in food or drinking water, expressed on a body mass basis (usually mg/kg body weight), which can be ingested daily over a lifetime by humans without appreciable health risk.
		ADI is normally used for food additives (tolerable daily intake is used for contaminants).
	www.bio.hw.ac.uk /edintox/AAIUPA.HTM (468 words)

	Injen Intake (Site not responding. Last check: 2007-10-20)
		An ideal intake system should increase the velocity of the air until it travels in to the combustion chamber, while minimizing turbulence and restriction of flow.
		Porsche in the 1980s designed an intake system for their cars that changed the length of the intake system by alternating between a longer and shorter set of tubing using a butterfly valve, creating a small amount of positive pressure which increased overall performance of the engine.
		However, the term "cold air intake" is often used to describe other methods of increasing oxygen to an engine, which may even increase the temperature of the air coming into an engine.
	www.blownspeakers.com /pages3/45/injen-intake.html (1041 words)

	Archives of Environmental Health: Evaluation of daily dietary intake of dichloro-diphenyl-trichloroethane and benzene ... (Site not responding. Last check: 2007-10-20)
		The dietary intake of DDT and BHC from nonfatty and fatty foods contributed almost equally to the total intake of these insecticides; however, a slight rise in consumption of fat could greatly increase the levels of these insecticides because their concentrations were comparatively higher in fatty food (Table 2).
		The average daily dietary intake of DDT and BHC determined on the basis of the 1-d duplicate diet method was 19.24 [mu]g and 77.15 [mu]g per person per day, respectively.
		The maximum acceptable daily intake for DDT from all sources is 20 [mu]g per kg body weight, as recommended by FAO/WHO.[15] No acceptable daily intake for BHC has been recommended by FAO/WHO because of variation in the composition of various isomers.
	www.findarticles.com /p/articles/mi_m0907/is_n1_v49/ai_14930026 (1108 words)

	[No title] (Site not responding. Last check: 2007-10-20)
		If the total acceptable daily intake of nickel is 78.4 Âµg Ni/day, the amount allocated to drinking water with a 20% RSC would be 16 Âµg Ni/day, producing a PHG of 8 Âµg Ni/l.
		Under the subtraction method, the expected intake of nickel from all sources other than drinking water is subtracted from the total acceptable daily intake of nickel, and the balance is allocated to drinking water.
		Under the subtraction method, a bioavailability-adjusted value of 20 Âµg Ni/day in dietary intake would be subtracted from a total acceptable daily intake of 78.4 Âµg Ni/day (which is based on an RfD from drinking water and gavage studies), and the balance of 58.4 Âµg Ni/day would be allocable to drinking water.
	www.nidi.org /index.cfm/ci_id/9925.htm (1335 words)

	Untitled Document
		acceptable daily intake(ADI): This is an estimate of the amount of substance in the food that can be ingested daily over a lifetime by humans without appreciable health risk.
		acceptable daily intake (pesticide residues): The acceptable daily intake of a chemical is the daily intake which, during an entire life time, appears to be without appreciable risk to the health of the consumer on the basis of all the known facts at the time when a toxicological assessment is carried out.
		no acceptable daily intake allocated: This expression is applicable to substances for which the available information is not sufficient to establish their safety or when the specifications for identity and purity are not adequate.
	www.regetox.med.ulg.ac.be /demo/dicoabcd.htm (5004 words)

	Why food additives? - The Acceptable Daily Intake (ADI) : a tool for legislators (Site not responding. Last check: 2007-10-20)
		he Acceptable Daily Intake (ADI) for man, expressed on a milligrams per kilogram of bodyweight basis, is the amount of a food additive than can be taken daily in the diet, even over a lifetime, without risk.
		This No Effect Level is then reinforced by a large safety factor, usually 100, to arrive at the ADI for man. For example, if the No Effect Level in an animal study is observed to be 100 mg/kg bodyweight, this is then converted to an ADI of 1 mg/kg bodyweight for humans.
		Although called an acceptable daily intake, the ADI should always be compared with average intakes over prolonged periods - not with day to day intakes.
	www.elc-eu.org /3.htm (306 words)

	Pesticides in Food (Site not responding. Last check: 2007-10-20)
		Acceptable Daily Intake is the daily intake of a chemical which, during the entire life-time of the consumer, appears to be "without appreciable risk" to health, as determined by experts meeting at the WHO/FAO.
		It can be argued that there is no acceptable daily intake of a substance like DDT which bioaccumulates and causes endocrine disruption at very low levels.
		The estimated daily intake for young children in the case of iprodione has risen nearly five times compared to the last total diet survey.
	www.soil-health.org.nz /organicnz/proceedings/PESTICIDESINFOOD.htm (3974 words)

	Codex Maximum Limits for Pesticide Residues (Site not responding. Last check: 2007-10-20)
		Codex MRLs are based on residue data from supervised trials and not directly derived from Acceptable Daily Intakes(ADIs) which is a quantitative expression of acceptable daily amounts of residue which persons may ingest on a long term basis and which are established on the basis of appropriate toxicological data mainly from animal studies.
		The acceptability of Codex MRLs is judged on the basis of a comparison of the acceptable daily intake with estimated daily intakes, as determined on the basis of suitable intake studies.
		Intake data from such studies, compared with acceptable daily intakes, help in determining the safety of foods in respect of pesticide residues.
	faostat.fao.org /faostat/pestdes/pest_ref/pest-e.htm (1972 words)

	ATSDR - Health Consultation - Brandy Branch Reservoir, Marshall, Harrison County, Texas
		In areas of China with selenium intakes of 3,200 to 6,690 ug per day, clinically apparent selenium toxicity was observed, while persons with daily intakes in the range of 42-750 ug per day did not produce any signs of toxicity or other adverse health effects [6].
		In performing the risk assessment, TDH determined the acceptable daily intake of selenium from fish by subtracting an assumed daily intake of selenium from other sources (200 µg/day [2.86 µg/kg/day assuming a 70 kg adult]) from the estimated safe and acceptable daily intake.
		Assuming a background daily intake of selenium from other sources of 200 µg we estimate that approximately 150 µg/day (2.14 µg/kg/day assuming a 70 kg adult) is an acceptable daily intake of selenium from fish.
	www.atsdr.cdc.gov /HAC/PHA/marshall/mar_p2.html (1716 words)

	BfR - Rucola may contain very high levels of nitrate
		Depending on individual eating habits, this may mean an intake of substantial amounts of nitrate and a clear exceeding of the Acceptable Daily Intake (ADI) recommended by WHO.
		The Acceptable Daily Intake (ADI) for nitrate recommended by WHO is 3.7 milligrams per kilogram body weight (mg/kg BW).
		At the present time, the average daily intake of nitrate in Germany is estimated to be between 80 and 100 mg.
	www.bfr.bund.de /cd/5983 (639 words)

	Acceptable daily intake - Wikipedia, the free encyclopedia
		Acceptable Daily Intake or ADI is a measure of a specific substance (usually a food additive) in food or drinking water that can be ingested over a lifetime without an appreciable health risk.
		ADIs are expressed by body mass, usually in milligrams per kilograms of body mass.
		Note that the ADI is considered a safe intake level for the healthy adult of normal weight who consumes the average amount of the substance in question, not for small children or weak persons.
	en.wikipedia.org /wiki/Acceptable_daily_intake (248 words)

	177. Appendix III (FAO/PL:1969/M/17/1)
		The information considered includes the results from subjective sampling and/or from objective sampling, including total diet studies, in various countries and particularly in where pesticides are most widely used.
		Nevertheless some regulatory methods are suitable for use as referee methods, although their evaluation by inter-laboratory comparisons is desirable before they are adopted as such.
		FURTHER WORK REQUIRED Further work required is work which met be done and properly reported before acceptable daily intakes and/or tolerances can be recommended or confirmed.
	www.inchem.org /documents/jmpr/jmpmono/v069pr32.htm (1878 words)

	Abstract from 1998 SRA-Europe Annual Meeting (Site not responding. Last check: 2007-10-20)
		Arsenic exposure was measured through a questionnaire on daily intakes of drinking water and other food with high proportion of water.
		The survey showed that the mean daily intake for water is similar in Seppois-le-Bas and Ferrette (1.8 liter).
		Messages for voluntary tap water intake reduction have failed to reduce the daily intake of Arsenic below the acceptable daily intake of 2mg/kg/d and to lower the theoretical risk of cutaneous cancer.
	www.riskworld.com /Abstract/1998/SRAEUR98/eu8ab048.htm (332 words)

	What is the acceptable daily intake of aspartame? (Site not responding. Last check: 2007-10-20)
		The acceptable daily intake (ADI) is established by the FDA and is an estimate of the amount of a food additive that can be consumed daily for a lifetime without adverse effects.
		The ADI of aspartame is 50 mg/kg of body weight per day (22 cans of a diet soft drink for a 175 pound man; 15 cans for a 120 pound woman).
		A study was conducted on the long-term administration of 75 mg/kg of aspartame per day using a randomized, double-blind, placebo-controlled, parallel-group design.
	www.aspartame.net /media/info/faq4.html (208 words)

	Glossary: Tolerable Daily Intake
		For chemicals that give rise to such toxic effects, a tolerable daily intake (TDI) should be derived as follows, using the most sensitive endpoint in the most relevant study, preferably in drinking water:
		Short-term exposure to levels exceeding the TDI is not a cause for concern, provided the individual’s intake averaged over longer periods of time does not appreciably exceed the level set.
		Acceptable Daily Intake - intake - LOAEL - NOAEL - threshold - uptake - uncertainty factor
	www.greenfacts.org /glossary/tuv/TDI-tolerable-daily-intake.htm (294 words)

	ific.org : Questions and Answers About Acceptable Daily Intake
		The Acceptable Daily Intake is defined as the amount of a food additive that can be ingested daily in the diet without appreciable risk on the basis of all facts known at the time.
		The ADI is a practical approach to determining the safety of food additives and is a means of achieving some uniformity of approach in regulatory control.
		The ADI is an acceptable level D as the name implies.
	www.ific.org /publications/qa/adiqa.cfm (589 words)

	Health and Consumer Protection - Scientific Committee on Food - Outcome of discussions 13
		To consider the applicability of the ADI (Acceptable Daily Intake) for food additives intended for use in foods for infants in the age of 0-16 weeks.
		The ADI describes the daily amount of a compound that an individual can be exposed to throughout life without adverse effects.
		The applicability of the ADI (Acceptable Daily Intake) for food additives to infants and children.
	europa.eu.int /comm/food/fs/sc/scf/out13_en.html (2486 words)

	Chemical Safety Glossary
		They are expressed as either the parent compound or a metabolite that is, or is representative of, the residue of toxicological concern in the food commodity.
		MRLs are not based upon toxicological data, but crude estimates of their toxicological significance are usually made by comparing the acceptable daily intake (ADI) with a calculation of the total intake of the residue based on the MRLs and food intake data of these commodities for which MRLs have been established.
		This term may be used in either of two ways depending upon the context (i) Mathematical expression of uncertainty applied to data that are used to protect populations from hazards which cannot be assessed with high precision.
	www.bio.hw.ac.uk /edintox/glossall.htm (6659 words)

	terbufos (Counter) EPA Pesticide Fact Sheet 9/88
		Based on the plasma cholinesterase inhibition no-effect-level of 0.00125 mg/kg/day as defined in a 4-week dog study and, using a safety factor of 10, the acceptable daily dietary intake for humans in 0.000125 mg/kg/day.
		This is equivalent to 42 percent of the acceptable daily intake for the average U.S. population.
		The acceptable short-term field study shows significant acute mortalities of birds, mammals, reptiles, and fish resulting from broadcast application of terbufos to corn fields at 1 pound active ingredient per acre (l lb ai/A).
	pmep.cce.cornell.edu /profiles/insect-mite/propetamphos-zetacyperm/terbufos/insect-prof-terbufos.html (2396 words)

	Acceptable daily intake and the regulation of intense sweeteners (Site not responding. Last check: 2007-10-20)
		Acceptable daily intake and the regulation of intense sweeteners.
		This review considers briefly the critical toxicity of each sweetener that is the basis for establishing the no adverse effect level in animal studies.
		The calculation of an acceptable daily intake (ADI) for human intake employs a large safety factor applied to the no-effect level.
	www.aspartame.net /media/scilib/abst53.html (141 words)

	Title 21 Code of Federal Regulations
		The acceptable daily intake (ADI) for total residues of apramycin is 25 micrograms per kilogram of body weight per day.
		Tolerances for total residues of combined arsenic (calculated as As) in food are established as follows: (a) In edible tissues and in eggs of chickens and turkeys: (1) 0.5 part per million in uncooked muscle tissue.
		The acceptable daily intake for enrofloxacin is 3 micrograms per kilogram of body weight per day.
	www.betterchem.com /21cfr/21cfr556.htm (10361 words)

	Acceptable daily intake (ADI) (Site not responding. Last check: 2007-10-20)
		This is an estimate of the amount of a substance in food that can be ingested daily over a lifetime by humans without appreciable health risk.
		The concept of the ADI has been developed principally by WHO and FAO and is relevant to chemicals such as additives to foods, residues of pesticides and veterinary drugs in foods.
		The ADI is thus an estimate of the amount of a substance in food that can be ingested over a lifetime by humans without significant risk to health (for contaminants in food and drinking water, tolerable intakes - daily or weekly - are used).
	www.cartage.org.lb /en/themes/Reference/dictionary/Biologie/A/80.html (124 words)

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