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Acetazolamide (PIM 005) Acetazolamide is distributed throughout body tissues; it concentrates principally in erythrocytes, plasma and kidneys and to a lesser extent in liver, muscles, eyes and the central nervous system. In the mouse, the LD50 is 3000 to 6000 mg/kg (Dollery, 1991) Acetazolamide overdoses should be evaluated according to the extent of volume depletion, the degree of electrolyte abnormality or acid-base disturbance, and the severity of the patient's underlying medical condition(s) and not according to the amount ingested. www.inchem.org /documents/pims/pharm/acetazol.htm   (3840 words)

MedlinePlus Drug Information: Acetazolamide Oral Acetazolamide is used to treat glaucoma, a condition in which increased pressure in the eye can lead to gradual loss of vision. Acetazolamide is also used to reduce the severity and duration of symptoms (upset stomach, headache, shortness of breath, dizziness, drowsiness, and fatigue) of altitude (mountain) sickness. Acetazolamide is used with other medicines to reduce edema (excess water retention) and to help control seizures in certain types of epilepsy. www.nlm.nih.gov /medlineplus/druginfo/medmaster/a682756.html   (660 words)

Parkinsn's List Drug DataBase acetazolamide, Diamox Acetazolamide has been used as a diuretic for edema due to congestive heart failure, but it has been replaced by thiazide and loop diuretics because it rapidly loses its diuretic effect and is less potent than other classes of diuretics. Acetazolamide is rapidly absorbedfrom the GI tract, and peak serum concentrations for the tablets and extended-release capsules are achieved in 2-4 hours and 8-12hours, respectively. Acetazolamide increases the excretion of bicarbonate and sodium, decreasing the extracellular fluid concentration of bicarbonate and causing metabolic acidosis. www.parkinsons-information-exchange-network-online.com /drugdb/002.html   (1684 words)

s000918c - cetazolamide (Diamox) in Chronic Renal Failure Acetazolamide (AZ) is mostly excreted in the urine, therefore, the blood levels of AZ often tend to increase in patients with chronic renal failure. Acetazolamide (500 mg) was administered daily for 7 days, after pretreatment for 1 month with 1,25-dihydroxyvitamin D (n = 12) or placebo (n = 12); only placebo was administered to a third group (n = 12) of haemodialysis patients. Acetazolamide was capable of preventing the excessive IOP rise during dialysis. www.emory.edu /WHSCL/grady/amreport/litsrch00/s000918c.html   (2458 words)

Acetazolamide/Aspirin Case On Mar. 11, acetazolamide was increased to 500 mg b.i.d. Total and unbound concentrations of acetazolamide in plasma were 20.8 microg/ml and 7.7 microg/ml, respectively, yielding an unbound percentage of acetazolamide in plasma of 37.1%. Acetazolamide levels were measured in plasma and plasma ultrafiltrate and salicylate in plasma, to give the data in Table II. www.umdnj.edu /~howland/Cases/acet_asp.html   (665 words)

Acetazolamide Acetazolamide is a potent carbonic anhydrase inhibitor, effective in the control of fluid secretion, in the treatment of certain convulsive disorders and in the promotion of diuresis in instances of abnormal fluid retention. Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect. Acetazolamide increases lithium excretion and the lithium may be decreased. www.mongabay.com /health/medications/Acetazolamide.html   (526 words)

View Study [NEI Clinical Studies] Recent reports suggested that acetazolamide, a carbonic anhydrase inhibitor that is used to lower intraocular pressure in some glaucoma patients, might be safe and effective in reducing uveitis-associated cystoid macular edema. Acetazolamide therapy resulted in 0.5 disc area (25 percent) decrease in cystoid macular edema over that of placebo (p = 0.01; estimated treatment effect = -0.5 disc areas, 95 percent confidence interval [-0.9, -0.1]). Acetazolamide therapy results in a statistically significant but small decrease in cystoid macular edema in patients with chronic uveitis but does not improve visual acuity. www.nei.nih.gov /neitrials/viewStudyWeb.aspx?id=11   (737 words)

acetazolamide - Fort Lauderdale, Florida Acetazolamide is used to treat glaucoma and to treat and to prevent acute mountain sickness (altitude sickness). Acetazolamide is also a sulfa-based drug, and you may have a similar reaction to it. Acetazolamide is in the FDA pregnancy category C. This means that it is not known whether acetazolamide will harm an unborn baby. www.browardhealth.org /19599.cfm   (1065 words)

Base Camp MD - Guide to High Altitude Medicine Acetazolamide (Diamox®) is a medication that forces the kidneys to excrete bicarbonate, the base form of carbon dioxide; this re-acidifies the blood, balancing the effects of the hyperventilation that occurs at altitude in an attempt to get oxygen. Acetazolamide is a sulfonamide medication, and persons allergic to sulfa medicines should not take it. Even on acetazolamide, it is still possible to ascend so rapidly that when illness strikes, it may be sudden, severe, and possibly fatal. www.basecampmd.com /expguide/diamox.shtml   (643 words)

Inhouse Pharmacy DIAMOX (acetazolamide)   (Site not responding. Last check: 2007-09-17) In the eye this inhibitory action of acetazolamide decreases the secretion of aqueous humour and results in a drop in intraocular pressure, a reaction considered desirable in cases of glaucoma and even in certain nonglaucomatous conditions. Acetazolamide is contraindicated in patients with cirrhosis because of the risk of development of hepatic encephalophathy. Pharmacokinetic studies in four volunteers showed that the plasma protein binding and renal clearance of acetazolamide were significantly reduced during chronic salicylate dosing. www.inhousepharmacy.com /neurological/diamox-information.html   (1517 words)

Acetazolamide and Breathing . Does a Clinical Dose Alter Peripheral and Central CO2 Sensitivity? -- TEPPEMA and DAHAN ... In both the placebo and acetazolamide condition, 2 to 3 DEF runs were performed in all subjects. Difference in the effects of acetazolamide and ammonium chloride acidosis on ventilatory responses to CO and hypoxia in humans. Reduction of the responses of carotid chemoreceptors by acetazolamide. ajrccm.atsjournals.org /cgi/content/full/160/5/1592   (3973 words)

Acetazolamide improves central sleep apnea in heart failure   (Site not responding. Last check: 2007-09-17) Since sleep apnea is associated with heart failure, patients who take a single dose of acetazolamide - a mild diuretic and respiratory stimulant - before going to bed exhibit less sleep apnea, improved blood oxygen levels and fewer daytime symptoms of sleepiness. In the past, acetazolamide's principal use has been to help treat breathing irregularities and sleep apneas occurring at high altitude. According to the authors, the 12 patients with stable heart failure were randomized to a double-blind cross-over protocol with either acetazolamide or placebo, taken one hour before bedtime over the course of six nights. www.news-medical.net /?id=15402   (557 words)

Acetazolamide in the treatment of seizures -- Reiss and Oles 30 (5): 514 -- The Annals of Pharmacotherapy OBJECTIVE: To summarize the pharmacology, pharmacokinetics, efficacy, and safety of acetazolamide and to evaluate its therapeutic role in patients with epilepsy. Acetazolamide is primarily used in combination therapy with other antiepileptic medications in both children and adults although it may be used as monotherapy. CONCLUSIONS: Acetazolamide is a beneficial adjunctive agent in the pharmacotherapy of epilepsy and should be considered in refractory epilepsy. www.theannals.com /cgi/content/abstract/30/5/514   (329 words)

Acetazolamide Acetazolamide may also be used in conjunction with other anti-epileptic medicines in the treatment of epilepsy. Acetazolamide may decrease the blood levels of primidone and increase that of carbamazepine. When acetazolamide is taken with other anti-epileptic medicines (phenobarbitone, phenytoin or primidone) there may be an increased risk of severe bone softening occurring. www2.netdoctor.co.uk /medicines/100004361.html   (811 words)

Acetazolamide - Wikipedia, the free encyclopedia Acetazolamide, sold under the trade name Diamox®, is a carbonic anhydrase inhibitor that is used to treat glaucoma, epileptic seizures, benign intracranial hypertension, altitude sickness, cystinuria, and dural ectasia. Acetazolamide is used in the treatment of various diseases. Acetazolamide, Ethoxzolamide, Sultiame, Zonisamide -- Propionates: Beclamide -- Aldehydes: Paraldehyde -- Bromides: Potassium bromide, Sodium bromide en.wikipedia.org /wiki/Acetazolamide   (623 words)

Acetazolamide-induced cerebral and ocular vasodilation in humans is independent of nitric oxide -- Kiss et al. 276 (6): ... Acetazolamide, a carbonic anhydrase inhibitor, is used orally in the treatment of primary and secondary open-angle glaucoma acetazolamide, a carbonic anhydrase inhibitor, is used in the treatment of primary and secondary open-angle As expected, acetazolamide induced strong vasodilation in ocular and cerebral vessels in the present study. ajpregu.physiology.org /cgi/content/full/276/6/R1661   (2739 words)

Acetazolamide - Patient UK Acetazolamide is a sulphonamide used to treat glaucoma. Acetazolamide works by reducing the production of fluid in the eye, relieving the pressure. Acetazolamide is available in tablet and injection form. www.patient.co.uk /showdoc/30002146   (703 words)

:: acetazolamide ::...   (Site not responding. Last check: 2007-09-17) acetazolamide were thoughts that puzzled Skippy's young brain oncein a while. The Mayor was in the acetazolamide authentical; but there it had stayed by him. Whatever the means by whichthe acetazolamide reveals the character-whether by setting, conduct,analysis, dialogue, or soliloquy-his task is a rare acetazolamide of your. farmsalehost.com /cgi/pills/acetazolamide.html   (248 words)

Dissociation of Vasoreactivity to Acetazolamide and Hypercapnia: Comparative Study in Patients With Chronic Occlusive ...   (Site not responding. Last check: 2007-09-17) Ipsilateral acetazolamide reactivity was preserved in 13 patients. Asymmetry ratio was significantly lower in acetazolamide than in CO in both subgroups with preserved and reduced acetazolamide reactivity (P<.05,.001, respectively). Scatterplot indicates the relationship of the vasoreactivity expressed by percent increase in CBF during hypercapnia and acetazolamide in the ipsilateral hemisphere. stroke.ahajournals.org /cgi/content/full/27/11/2052   (3806 words)

Acetazolamide - Buy Acetazolamide Online - Fda approved Acetazolamide without a Prescription at NPMeds.com Acetazolamide is Dispatched from outside the United States. If Acetazolamide will not be delivered to you within 20 days, we will repeat the sending or we will return your money. Common misspellings of Acetazolamide: ocetazolamide, scetazolamide, axetazolamide, avetazolamide, acitazolamide, acwtazolamide, acerazolamide, aceyazolamide, acetozolamide, acetszolamide, acetaaolamide, acetaxolamide, acetazilamide, acetazplamide, acetazokamide, acetazo;amide, acetazolomide, acetazolsmide, acetazolanide, acetazola,ide, acetazolamede, acetazolamude, acetazolamise, acetazolamife, acetazolamidi, acetazolamidw, www.npmeds.com /fda/online/Acetazolamide.shtml   (235 words)

[No title] Acetazolamide (Diamox) -- Carbonic anhydrase inhibitor diuretic used for its respiratory-stimulant effects. May be administered for prophylactic use in patients with a prior history of HAPE. Acetazolamide (Diamox) may be used to stimulate breathing, speed acclimatization, and diminish the milder symptoms of acute mountain sickness. www.lycos.com /info/diamox--acetazolamide.html   (181 words)

AcetaZOLAMIDE Hypersensitivity to acetazolamide, sulfonamides, or any component of the formulation; hepatic disease or insufficiency; decreased sodium and/or potassium levels; adrenocortical insufficiency, cirrhosis; hyperchloremic acidosis, severe renal disease or dysfunction; severe pulmonary obstruction; long-term use in noncongestive angle-closure glaucoma Lithium: Acetazolamide increases lithium excretion; lithium serum levels may be decreased. Chapron DJ, Gomolin IH, and Sweeney KR, "Acetazolamide Blood Concentrations Are Excessive in the Elderly: Propensity for Acidosis and Relationship to Renal Function,"J Clin Pharmacol, 1989, 29(4):348-53. www.metagenics.com /ADAM/41/000700.html   (1566 words)

Use of acetazolamide to decrease cerebrospinal fluid production in chronically ventilated patients with ... Acetazolamide (ACTZ), a carbonic anhydrase inhibitor, has been shown to decrease CSF production in animal models and is used Childhood pseudotumor cerebri: clinical and intracranial pressure response to acetazolamide and furosemide treatment in a case series. Management of hydrocephalus in infancy: use of acetazolamide and furosemide to avoid cerebrospinal shunts. adc.bmj.com /cgi/content/full/84/1/68   (2159 words)

Acetazolamide Drug Information Acetazolamide is also used as an anticonvulsant to control certain seizures in the treatment of epilepsy. It is also sometimes used to prevent or lessen some effects in mountain climbers who climb to high altitudes, and to treat other conditions as determined by your doctor. If you have been taking acetazolamide regularly for several weeks or more, do not suddenly stop taking it. www.drugs.com /cons/Acetazolamide.html   (2212 words)

Sex-Related Differences in Acetazolamide-Induced Cerebral Vasomotor Reactivity -- Karnik et al. 27 (1): 56 -- Stroke   (Site not responding. Last check: 2007-09-17) measured by an increased vasodilatory response to the acetazolamide Evaluation of vasomotor reactivity by transcranial Doppler sonography and acetazolamide test before and after extra-intracranial bypass in patients with internal carotid artery occlusion. Vorstrup S, Brun B, Lassen N. Evaluation of cerebral vasodilatory capacity by the acetazolamide test before EC-IC bypass surgery in patients with occlusion of the internal carotid artery. stroke.ahajournals.org /cgi/content/full/27/1/56   (1658 words)

Acetazolamide Why it is prescribed : Acetazolamide is used to treat glaucoma and petitmal epilepsy.It reduces pressure in the eye. It is also used as a diuretic which cause a net loss of water in urine. Acetazolamide is also used in treating acute mountain sickness and to promote excretion of certai acidic drugs.It is also used to reduce the severity of symptoms like nausea,vomiting,dizziness,drowsiness and fatigue. medindia.net /doctors/drugsdetails.asp?d1=Acetazolamide   (280 words)

Acetazolamide - Talk Medical · Acetazolamide is used to treat glaucoma and to treat and to prevent acute mountain sickness (altitude sickness). · Acetazolamide is in the FDA pregnancy category C. This means that it is not known whether Acetazolamide will harm an unborn baby. · Symptoms of an Acetazolamide overdose are not well known, but the following symptoms might be expected: drowsiness, decreased appetite, nausea, vomiting, dizziness, numbness or tingling, shaking, and ringing in the ears. www.talkmedical.com /medications/58/Acetazolamide   (724 words)

Clinical Trial: Acetazolamide for Respiratory Failure in Combination With Metabolic Alkalosis When a patient with an acute exacerbation of a respiratory failure is also alkalotic, there are (at least theoretical) reasons to lower the pH in order to increase the respiratory drive. In some hospitals there is a tradition for the use of acetazolamide on this indication, but any evidence for the effect of such a treatment is rather weak. Thus, the aim of this trial is to evaluate the effect of acetazolamide as an adjuvant treatment for hospitalized patients with acute exacerbation of respiratory failure in combination with metabolic alkalosis. clinicaltrials.gov /ct/show/NCT00222534   (446 words)

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