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Topic: Acetyl coenzyme A

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Acetyl CoA

Hans Adolf Krebs

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	Coenzyme-A Technologies Inc. Formation of Acetyl Coenzyme-A
		Summary: Pyruvate is degraded and combined with Coenzyme-A to form acetyl coenzyme A; hydrogens are released; and carbon dioxide is released.
		Finally, the oxidized two-carbon fragment, an acetyl group, is attached to Coenzyme-A, which is manufactured in the cell from one of the B vitamins, pantothenic acid.
		Coenzyme-A is a "helper" molecule important in many metabolic processes.
	www.coenzymea.com /acetyl.html (549 words)

	Dorlands Medical Dictionary
		Acetyl CoA can enter the tricarboxylic acid cycle, can be used to acetylate numerous compounds, and can be a precursor of steroids and other isoprenoid compounds.
		Excess acetyl coenzyme A may be converted to fats for storage or may appear as ketone bodies.
		(as”ə-təl-, as”ə-tēl”di-hi”dro-lĭ-po-am´īd) acetyl bound to lipoamide, an intermediate in the reaction catalyzed by the pyruvate dehydrogenase complex (q.v.).
	www.mercksource.com /pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszSzcommonzSzdorlandszSzdorlandzSzdmd_a_07zPzhtm (2006 words)

	Acetyl coenzyme a synthetase fusion proteins - Patent 6013496
		An isolated acetyl coenzyme A synthetase (ACS) fusion protein, wherein the ACS portion of the fusion protein is encoded by DNA contained in the plasmid pUC19-pAR8, deposited as ATCC 209191.
		Acetate as acetyl coenzyme A (acetyl-CoA) is a major substrate for milk synthesis and occupies a central position in metabolism of Holstein mammary gland as well as in both prokaryotic and eukaryotic cells.
		Acetyl coenzyme A synthetase was assayed using the acetate dependent disappearance of the sulfhydryl group of coenzyme A as described by Qureshi et al.
	www.freepatentsonline.com /6013496.html (16763 words)

	Acetyl-coenzyme A synthetase is a lipogenic enzyme controlled by SREBP-1 and energy status -- Sone et al. 282 (1): 222 ...
		in the NCBI GenBank as a murine ACAS cDNA (AF216873).
		Luciferase reporter genes containing the mouse ACAS promoter region (668 bp) and its sequential deleted fragments in the context of presence or absence of the SRE were constructed and transfected with a CMV promoter expression vector of nuclear SREBP-1a or an empty control vector, and pRL-SV40 as a reference plasmid into HepG2 cells.
		The decreased ACAS expression in the mouse liver by oral administration of acetate is implicative.
	ajpendo.physiology.org /cgi/content/full/282/1/E222 (5073 words)

	Plant gene specifying acetyl coenzyme A carboxylase and transformed plants containing same - US Patent 6455688 (Site not responding. Last check: 2007-10-25)
		A method of transcribing the structural region of the gene construct as claimed in claim 4 comprising inducing the promoter of the gene construct and thereby transcribing the structural region which is in the antisense orientation.
		Acetyl Coenzyme A carboxylase is one of the genes involved in the synthesis of oil by oil-producing crops such as oilseed rape.
		However, the synthesis of fatty acids which are the building blocks of plant oils utilise the substrate acetyl Coenzyme A which is the same substrate required by the polyhydroxyalkanoate genes.
	www.patentstorm.us /patents/6455688.html (7816 words)

	Inhibition of Escherichia coli Acetyl Coenzyme A Carboxylase by Acyl-Acyl Carrier Protein -- Davis and Cronan 183 (4): ...
		Inhibition of Escherichia coli Acetyl Coenzyme A Carboxylase by Acyl-Acyl Carrier Protein -- Davis and Cronan 183 (4): 1499 -- The Journal of Bacteriology
		Inhibition of Escherichia coli Acetyl Coenzyme A Carboxylase by Acyl-Acyl Carrier Protein
		Escherichia coli acetyl coenzyme A carboxylase (ACC), the first enzyme of the fatty acid biosynthetic pathway, is inhibited
	jb.asm.org /cgi/content/full/183/4/1499 (2883 words)

	ACAS2 - Acetyl-coenzyme A synthetase, cytoplasmic
		Acetylation of the Chemotaxis Response Regulator CheY by Acetyl-CoA Synthetase Purified from Escherichia coli.
		Previously it was shown that the expression of the FATP-1 and ACS genes was controlled by insulin and by peroxisome proliferator- activated receptor (PPAR) agonists in liver or in adipose tissue.
		Acetylation of CheY, the excitatory response regulator of bacterial chemotaxis, by the enzyme acetyl-CoA synthetase (Acs) is involved in Escherichia coli chemotaxis, but its function is obscure.
	www.pdg.cnb.uam.es /UniPub/iHOP/gg/100900.html (2575 words)

	ACETYL COENZYME A (Site not responding. Last check: 2007-10-25)
		Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids.
		It also acts as a biological acetylating agent.
		All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro.
	www.websters-online-dictionary.org /Ac/Acetyl+Coenzyme+A.html (120 words)

	MSN Encarta - Dictionary - acetyl coenzyme A
		MSN Encarta - Dictionary - acetyl coenzyme A
		Search for "acetyl coenzyme A" in all of MSN Encarta
		coenzyme of metabolism: a coenzyme produced during metabolism of carbohydrates, fatty acids, and amino acids
	encarta.msn.com /dictionary_1861583354/acetyl_coenzyme_A.html (63 words)

	Ontogenesis of a biological clock for serotonin:acetyl coenzyme A N-acetyltransferase in pineal gland of rat. (Site not responding. Last check: 2007-10-25)
		Ontogenesis of a biological clock for serotonin:acetyl coenzyme A N-acetyltransferase in pineal gland of rat.
		Serotonin:acetyl coenzyme A N-acetyltransferase (EC 2.3.1.5) Activity in pineal gland was assayed in rats which were born and raised under diurnal lighting conditions, in continuous darkness, or in constant light.
		N-Acetyltransferase activity in the pups raised under diurnal lighting showed a rhythmic pattern, with high enzyme activity during dark period.
	www.arclab.org /medlineupdates/abstract_1058497.html (332 words)

	Nucleotide Variability at the Acetyl Coenzyme A Carboxylase Gene and the Signature of Herbicide Selection in the Grass ...
		Nucleotide Variability at the Acetyl Coenzyme A Carboxylase Gene and the Signature of Herbicide Selection in the Grass Weed Alopecurus myosuroides (Huds.) -- Délye et al.
		Nucleotide Variability at the Acetyl Coenzyme A Carboxylase Gene and the Signature of Herbicide Selection in the Grass Weed Alopecurus myosuroides (Huds.)
		Acetyl coenzyme A carboxylase (ACCase) is the target of highly
	mbe.oupjournals.org /cgi/content/abstract/21/5/884 (294 words)

	A Novel Cold-Sensitive Allele of the Rate-Limiting Enzyme of Fatty Acid Synthesis, Acetyl Coenzyme A Carboxylase, ...
		Acetyl coenzyme A carboxylase: filamentous nature of the animal enzymes.
		is synthetically lethal with two conditional alleles of the acetyl coenzyme A carboxylase gene and causes a defect in nuclear export of polyadenylated RNA.
		A yeast acetyl coenzyme A carboxylase mutant links very-long-chain fatty acid synthesis to the structure and function of the nuclear membrane-pore complex.
	mcb.asm.org /cgi/content/full/20/9/2984 (6245 words)

	A Novel Cold-Sensitive Allele of the Rate-Limiting Enzyme of Fatty Acid Synthesis, Acetyl Coenzyme A Carboxylase, ...
		A Novel Cold-Sensitive Allele of the Rate-Limiting Enzyme of Fatty Acid Synthesis, Acetyl Coenzyme A Carboxylase, Affects the Morphology of the Yeast Vacuole through Acylation of Vac8p -- Schneiter et al.
		A Novel Cold-Sensitive Allele of the Rate-Limiting Enzyme of Fatty Acid Synthesis, Acetyl Coenzyme A Carboxylase, Affects the Morphology of the Yeast Vacuole through Acylation of Vac8p
		Shirra, M. K., Patton-Vogt, J., Ulrich, A., Liuta-Tehlivets, O., Kohlwein, S. D., Henry, S. A., Arndt, K. Inhibition of Acetyl Coenzyme A Carboxylase Activity Restores Expression of the INO1 Gene in a snf1 Mutant Strain of Saccharomyces cerevisiae.
	mcb.asm.org /cgi/content/abstract/20/9/2984 (534 words)

	Molecular Characterization of Lactobacillus plantarum Genes for {beta}-Ketoacyl-Acyl Carrier Protein Synthase III ...
		Molecular Characterization of Lactobacillus plantarum Genes for {beta}-Ketoacyl-Acyl Carrier Protein Synthase III (fabH) and Acetyl Coenzyme A Carboxylase (accBCDA), Which Are Essential for Fatty Acid Biosynthesis -- Kiatpapan et al.
		coenzyme A (acetyl-CoA) carboxylase (ACC) is an enzyme that is
		Organization and nucleotide sequences of the genes encoding the biotin carboxyl carrier protein and biotin carboxylase protein of Pseudomonas aeruginosa acetyl coenzyme A carboxylase.
	aem.asm.org /cgi/content/full/67/1/426 (4920 words)

	ACAT2 Acetyl-Coenzyme A acetyltransferase 2 acetoacetyl Coenzyme A thiolase Antibody Search - Biocompare
		Your search for "ACAT2 (Acetyl-Coenzyme A acetyltransferase 2; acetoacetyl Coenzyme A thiolase" antibody returned 1 antibodies.
		Chicken Anti-ACAT2 (Acetyl-Coenzyme A acetyltransferase 2; acetoacetyl Coenzyme A thiolase Polyclonal Antibody, Unconjugated
		Price information is approximate list price and actual prices may vary.
	www.biocompare.com /matrixsc/3194/2/6/8742/ACAT2+(Acetyl-Coenzyme+A+acetyltransferase+2%3B+acetoacetyl+Coenzyme+A+thiolase (153 words)

	The Two Acetyl-coenzyme A Synthetases of Saccharomyces cerevisiae Differ with Respect to Kinetic Properties and ...
		-malate (pH 7.7), 0.2 µmol of coenzyme A, 8 µmol of ATP (pH 7.5), 1 µmol of NAD
		Activity of acetyl-coenzyme A synthetase with propionate as a substrate was determined in a discontinuous assay, measuring
		the propionate dependent consumption of coenzyme A (21).
	www.jbc.org /cgi/content/full/271/46/28953 (4919 words)

	Acetyl-coenzyme A synthetase is a lipogenic enzyme controlled by SREBP-1 and energy status -- Sone et al. 282 (1): 222 ...
		ACAS gene identified a sterol regulatory element with an adjacent
		and activation of the ACAS gene by gel shift and luciferase reporter
		expression demonstrate that ACAS is a novel hepatic lipogenic
	ajpendo.physiology.org /cgi/content/abstract/282/1/E222 (613 words)

	Nucleic acid encoding a family of acetyl-coenzyme-A transporter proteins, and products related thereto - Patent 5851788 (Site not responding. Last check: 2007-10-25)
		Kanamori et al., "Diversity of Sialospingolipids with Modification of Sialic Acid by Acetyl Group and Molecular cloning of a cDNA Encoding a Novel Membrane Protein Responsible for Acetylation", Abstract Booklet, International Symposium on Molecular and Cell Biology of Glycoconjugate Expression, (Aug.13, 1996).
		Varki and Diaz, "The Transport and Utilization of Acetyl Coenzyme A by Rat Liver Golgi Vesicles", The Journal of Biological Chemistry, 260/11: 6600-6608 (1985).
		Invention AT proteins are further characterized by having the ability to indirectly facilitate the acetylation of sialic acid residues of gangliosides GD3 and GT3.
	www.freepatentsonline.com /5851788.html (12690 words)

	IngentaConnect Acetyl Coenzyme A Carboxylase Activity in Neonatal Rat Cardiac My... (Site not responding. Last check: 2007-10-25)
		IngentaConnect Acetyl Coenzyme A Carboxylase Activity in Neonatal Rat Cardiac My...
		Acetyl Coenzyme A Carboxylase Activity in Neonatal Rat Cardiac Myocytes in Culture: Citrate Dependence and Effects of Hypoxia
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	api.ingentaconnect.com /content/ap/bb/1996/00000325/00000002/art00031 (392 words)

	Possible involvement of acetyl coenzyme A carboxylase as well as fatty acid synthetase in the temperature-controlled ...
		Possible involvement of acetyl coenzyme A carboxylase as well as fatty acid synthetase in the temperature-controlled synthesis of fatty acids in Saccharomyces cerevisiae -- Hori et al.
		Possible involvement of acetyl coenzyme A carboxylase as well as fatty acid synthetase in the temperature-controlled synthesis of fatty acids in Saccharomyces cerevisiae
		Molecular Cloning and Characterization of Two Genes for the Biotin Carboxylase and Carboxyltransferase Subunits of Acetyl Coenzyme A Carboxylase in Myxococcus xanthus
	jb.oupjournals.org /cgi/content/abstract/101/4/949 (389 words)

	Effect of tumor necrosis factor on acetyl-coenzyme A carboxylase gene expression and preadipocyte differentiation -- ...
		investigate the effect of recombinant TNF on the expression of acetyl-
		coenzyme-A (CoA) carboxylase, the rate-limiting enzyme for long-chain fatty
		We used a preadipocyte cell line, 30A-5, derived from
	mend.endojournals.org /cgi/content/abstract/2/5/395 (498 words)

	Determination of acetyl coenzyme A. Interference by a contaminant in malate dehydrogenase -- Mulder 13 (4): 552 -- ...
		Articles by Mulder, I. Journal of Lipid Research, Vol.
		Determination of acetyl coenzyme A. Interference by a contaminant in malate dehydrogenase
		the amount of acetyl CoA in solutions containing acetoacetyl
	www.jlr.org /cgi/content/abstract/13/4/552 (106 words)

	acetyl-coenzyme A carboxylase
		(Z24449) acetyl CoA carboxylase [Zea mays] 176 4e-44
		gi1335966 (U58598) acetyl CoA carboxylase [Zea mays] 176 5e-44
		gi992917 (L42814) acetyl CoA carboxylase [Glycine max] 124 2e-28
	www.canr.msu.edu /lgc/seq-bla-check/D39088.html (270 words)

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