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Topic: Acral lentiginous melanoma

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	Acral lentiginous melanoma misdiagnosed as verruca plantaris: A case report
		Acral lentiginous melanoma is the most common type of melanoma found in individuals with darkly pigmented skin (natives of Asia, India, Africa, and African-Americans); it also constitutes a smaller proportion of all melanomas found in fair-skinned persons [1, 2, 3, 4].
		Acral lentiginous melanoma is found on the digits, palms, soles, dorsum of the foot, and in the subungual area [1, 2, 3, 4, 5, 6, 7].
		Acral lentiginous melanoma can be mistaken for a variety of alternative diagnoses, including verruca, corn or callus, eccrine poroma, pyogenic granuloma, ischemic ulceration, mal perforans from a peripheral neuropathy, gangrene, superficial fungal infection, traumatic residual, foreign body, and benign nevus [10, 11, 13].
	dermatology.cdlib.org /124/case_reports/melanoma/rosen.html (1041 words)

	Dr. Koop - Melanoma- Health Encyclopedia and Reference
		Melanoma is a type of cancer originating from the cells that give color to the skin.
		Treatment of melanoma that has not spread beyond the original area of growth (especially if it is thin and has not invaded the primary dermis) is highly effective, and most of these cancers can be cured.
		Melanoma that has spread to distant sites is infrequently curable with standard therapy, although long-term survival is occasionally achieved by resection of metastasis.
	www.drkoop.com /encyclopedia/408/187/Melanoma.html (1414 words)

	Melanoma - Wikipedia, the free encyclopedia
		Melanoma is a malignant tumor of melanocytes and, less frequently, of retinal pigment epithelial cells (of the eye, see uveal melanoma).
		Lentigo maligna, a superficial melanoma confined to the topmost layers of the skin (found primarily in older patients) is often described as a "stain" on the skin.
		Treatment of advanced malignant melanoma is performed from a multidisciplinary approach including dermatologists, medical oncologists, radiation oncologists, surgical oncologists, general surgeons, plastic surgeons, neurologists, neurosurgeons, otorynolaryngologists, radiologists, pathologists/dermatopathologists, research scientists, nurse practitioners and physician assistants, and palliative care experts.
	en.wikipedia.org /wiki/Melanoma (3892 words)

	Acral lentiginous melanoma - Wikipedia, the free encyclopedia
		Acral lentiginous melanoma is a kind of skin melanoma.
		This is the most common form of melanoma in Asians and Blacks.
		This type of melanoma occurs on non hair baring surfaces of the body which may or may not be exposed to sunlight.
	en.wikipedia.org /wiki/Acral_lentiginous_melanoma (178 words)

	Acral lentiginous melanoma
		The etiology of this kind of melanoma seems to be the same as the others.
		Those lesions localized in fingers, in all cases the management is with amputation, generally amputations of digits are performed proximal to the distal joint of the thumb and at the middle interphalangeal joint of the fingers.
		The survival in patients with acral lentiginous melanoma is similar to the others subtypes of melanomas.
	www.imbiomed.com.mx /Cancerologia/Cav44n4/english/Zca84-09.html (242 words)

	Acral Lentiginous Melanoma
		Acral lentiginous melanoma (ALM) is the fourth distinct variant of cutaneous melanoma.
		Acral lentiginous melanoma in situ: a study of nine cases.
		Acral lentiginous melanoma: an immunohistochemical study of 20 cases.
	www.histopathology-india.net /ALM.htm (382 words)

	Melanoma: Acral Lentiginous Melanoma
		However, not all plantar or solar melanomas are acral lentiginous lesions; a minority are superficial spreading or nodular melanomas.
		Acral lentiginous melanoma is primarily seen in older patients.
		There is some evidence that lentigo maligna melanoma, acral lentiginous melanoma, and desmoplastic melanoma may have a different etiology and natural history, with the former having a more favorable prognosis and the latter two having a less favorable prognosis.
	www.lycos.com /info/melanoma--acral-lentiginous-melanoma.html (404 words)

	Melanoma: What it Looks Like (Site not responding. Last check: 2007-10-16)
		While only 4% of diagnosed skin cancer is melanoma, melanoma is the most serious form of skin cancer because of its ability to spread.
		Melanoma often develops in a pre-existing mole that begins to change or a new mole.
		It is estimated that 20% to 40% of melanomas arise from an atypical mole.
	www.skincarephysicians.com /skincancernet/melanoma.html (581 words)

	Melanoma - What are the types of melanoma? \| Advocate Health Care
		Generally, this type of melanoma is characterized by a pre-existing mole that slowly changes over a period of one to five years and which is then followed by a period of rapid changes close to the time that the melanoma is diagnosed.
		Acral lentiginous melanomas generally occur on the palms of the hand or the soles of the feet.
		Acral lentiginous melanoma is usually seen in persons who are over the age of 60.
	www.advocatehealth.com /system/info/library/articles/cancercare/mel4.html (420 words)

	Acral lentiginous melanoma Khandpur S, Reddy BSN - Indian J Dermatol Venereol Leprol
		Acral lentiginous melanoma (ALM) is the fourth clinicopathologic variant of malignant melanoma recognized and introduced by Reed in 1975.
		Melanomas of acral lentiginous type show distinct clinical and histologic features that are characteristically different from the other commoner variants.
		Nodular malignant melanoma - secondary to carcinoma rectum.
	www.ijdvl.com /article.asp?issn=0378-6323;year=2000;volume=66;issue=1;spage=37;epage=38;aulast=Khandpur (814 words)

	Melanoma
		Melanoma has the dubious distinction of being the most common cancer in women between the ages of 25 and 29 years of age, and is second to breast cancer in the 30 to 35 year age group.
		There are five types of melanoma with the prognosis being dependent not on the size of the lesion but on the depth into the skin that it penetrates.
		Melanoma can be diagnosed by routine physical examinations and noting if you have a first degree relative have a history of unusual moles or melanoma.
	www.pvderm.com /Melanoma.htm (612 words)

	[No title]
		However, not all plantar or solar melanomas are acral lentiginous lesions; a minority are superficial spreading or nodular melanomas.
		Acral lentiginous melanoma is primarily seen in older patients.
		There is some evidence that lentigo maligna melanoma, acral lentiginous melanoma, and desmoplastic melanoma may have a different etiology and natural history, with the former having a more favorable prognosis and the latter two having a less favorable prognosis.
	espanol.lycos.com /info/melanoma--acral-lentiginous-melanoma.html (404 words)

	Melanoma (Site not responding. Last check: 2007-10-16)
		It rarely produces problems locally as do BCC and SCC, but works its destruction through spread to distant organs ("metastasis.)" Melanomas are in part so dangerous because of their "innocent" appearance an behavior.
		Most melanomas probably develop in normal skin, but some are known to arise from previously benign pigmented lesions.
		"Lentigo maligna" melanoma - melanoma arising in a large plaque of pigment known as a lentigo maligna (or "Hutchinson's freckle") on the face of an elderly person.
	www.nypsa.com /frps/melanoma.html (220 words)

	Melanoma: Signs and symptoms - MayoClinic.com
		The first sign of melanoma is often a change in an existing mole or the development of a new, unusual-looking growth on the skin.
		Melanomas can also develop in areas of your body that have little or no exposure to the sun, such as the spaces between your toes and on your palms, soles, scalp or genitals.
		On the other hand, melanomas that occur in the lining of your eyelids (conjunctiva) or the pigmented coating within your eyeball (choroid) may cause a scratchy feeling under your eyelid or a dark spot in your vision.
	www.mayoclinic.com /health/melanoma/DS00439/DSECTION=2& (1097 words)

	eMedicine - Malignant Melanoma : Article Excerpt by: Susan M Swetter, MD
		Background: Melanoma is a malignancy of pigment-producing cells (melanocytes) located predominantly in the skin, but also found in the eyes, ears, GI tract, leptomeninges, and oral and genital mucous membranes.
		Primary cutaneous melanoma may develop in precursor melanocytic nevi (common, congenital, and atypical/dysplastic types), although more than 60% of cases are believed to arise de novo (ie, not from a preexisting pigmented lesion).
		The development of melanoma is multifactorial and appears to be related to multiple risk factors, including fair complexion, excessive childhood sun exposure and blistering childhood sunburns, an increased number of common and dysplastic moles, a family history of melanoma, the presence of a changing mole or evolving lesion on the skin, and, importantly, older age.
	www.emedicine.com /derm/byname/malignant-melanoma.htm (610 words)

	Melanoma - Better Health Channel.
		Melanomas on the arms and legs are usually detected earlier and have a better chance of cure than melanomas on the body, neck or head (which are usually detected at a later stage).
		In its early stages, melanoma is confined to the uppermost layer of the skin (epidermis).
		A melanoma may appear as a new spot or as a change in the appearance of an existing mole or freckle.
	www.betterhealth.vic.gov.au /bhcv2/bhcarticles.nsf/pages/Melanoma?OpenDocument (759 words)

	Melanoma In Situ
		In correspondence with their dermoscopic pattern, in these early lesions of acral melanomas, proliferation of solitary arranged melanocytes was mainly detected in the crista profunda intermedia, the epidermal rete ridge underlying the ridge of the skin marking.
		Lentiginous melanoma: a histologic pattern of melanoma to be distinguished from lentiginous nevus.
		The initial biopsies mimicked lentiginous nevus or dysplastic nevus and were characterized by a lentiginous proliferation of melanocytes at the dermoepidermal junction both as single cells and as small nests with areas of confluent growth, extending to the edges of the biopsy.
	www.thedoctorsdoctor.com /diseases/melanoma_in_situ.htm (6322 words)

	Melanoma - Lentigo, Acral Lentiginous, Superficial Spreading - Guide4Living
		Melanoma is the most deadly form of skin cancer as it is more likely than any other to spread to other parts of the body.
		A type of melanoma which is commonly found on areas of the body that aren't normally exposed to the sun such as the soles of the feet or the palms of the hands.
		There are other types of melanoma, although they are very rare, such as subungual melanoma which looks very much like a bruise under the finger or toenails and amelanotic melanoma (in which the melanoma loses its pigment so may only be detectable on detailed examination of the skin).
	www.guide4living.com /skincancer/melanoma.htm (597 words)

	About Melanoma (Site not responding. Last check: 2007-10-16)
		Melanoma is a malignant tumor that originates in melanocytes, the cells which produce the pigment melanin that colors our skin, hair, and eyes and is heavily concentrated in most moles.
		Invasive melanomas are the more serious, as they have penetrated more deeply into the skin and may have traveled from the original tumor through the body.
		The melanoma can be seen almost anywhere on the body, but is most likely to occur on the trunk in men, the legs in women, and the upper back in both.
	www.skincancer.org /melanoma/index.php (943 words)

	Melanoma
		Melanoma is most often diagnosed in older people; however, younger adults, teenagers and even children can be affected if their exposure to UV radiation is very high.
		Melanomas on the arms and legs have a better chance of cure than melanomas on the body, neck or head.
		In its early stages, melanoma is confined to the uppermost layer of the skin (epidermis) - the biopsy to remove the melanoma and surrounding tissue may be all the treatment required.
	www.disability.vic.gov.au /dsonline/dsarticles.nsf/pages/Melanoma?OpenDocument (624 words)

	Dermatology - Melanoma (Site not responding. Last check: 2007-10-16)
		Malignant melanoma is a cancerous neoplasm of the pigment-forming cells of the skin; the melanocyte and the nevus cell.
		Melanoma is less common in dark-skinned people, where the lesions occur on the palms of the hands and soles of the feet.
		Acral lentiginous melanomas are the most common melanoma in Blacks, Asians, and Hispanics (35-60 percent) but are infrequent in Caucasians (2-8 percent).
	cybermed.ucsd.edu /derm1/Melanoma/4dermweb1.html (1438 words)

	Malignant melanoma
		These are: superficial spreading, nodular, lentigo maligna, and acral lentiginous melanomas, accounting for 70%, 15% to 30%, 4% to 10%, and 2% to 8% of cases, respectively.
		The subtype also may influence where the tumor develops; lentigo melanoma is more common on the face while acral lentiginous melanoma is more common on the palms of the hand, soles of the feet, or in the nail beds.
		Though it is difficult to prove that sunscreens statistically reduce the frequency of malignant melanoma at this time, most authorities recommend their use as protection from ultraviolet light (considered a major factor in the development of melanoma.) Avoidance of severe sunburns is recommended.
	www.healthatoz.com /healthatoz/Atoz/ency/malignant_melanoma.jsp (3980 words)

	Melanoma
		Melanoma is a malignant skin cancer that presents as a spot with irregular borders and colors of tan, blue, fl, red or white.
		Melanoma is one of the most serious types of skin cancer.
		Acral Lentiginous Melanoma: This type of melanoma is rare and is most common among African-American and Asian people.
	www.yourskindoctor.com /topics/Skin_Cancers/Melanoma/melanoma.html (736 words)

	acral lentiginous melanoma - General Practice Notebook (Site not responding. Last check: 2007-10-16)
		Acral lentiginous melanoma is seen on the soles and less often, the palms.
		It has a raised dark area surrounded by a paler macular - lentiginous - area often extending for several centimetres around the elevation.
		Periungual melanoma may be regarded as a variant of acra-lentiginous melanoma.
	www.gpnotebook.co.uk /cache/-1415970783.htm (150 words)

	Types of Melanoma
		Superficial spreading melanomas are flat or slightly elevated brown lesions with fl, blue or pink discoloration which are typically greater than 6 mm in diameter and have irregular asymmetric borders.
		These melanomas may be found on any body surface, especially the head, neck, and trunk of males and the lower extremities of females.
		Lentigo maligna melanomas are typically found on sun-exposed areas of the skin in adults and are clearly linked to exposure to the sun.
	www.training.seer.cancer.gov /ss_module14_melanoma/unit01_sec02_types.html (371 words)

	Melanoma
		While all melanomas evolve from a single type of cell, the melanocyte, melanoma is further divided into four sub-types each with their own prognosis and rate of metastasis.
		Acral lentiginous melanoma is the most common subtype for people with dark skin: sixty percent of melanomas diagnosed in darker-skinned people are ALM.
		Acral lentiginous melanoma has a radial growth pattern, and is most often found on the palms, soles and under the fingernails.
	www.about-skin-disorders.com /melanoma/melanoma-types.php (765 words)

	Melanoma Center - Risk Factors - Race (Site not responding. Last check: 2007-10-16)
		Acral lentiginous melanoma is the most common melanoma in African Americans and Asians.
		Because of the misconceptions that melanomas only occur in sun-exposed areas, and that dark-skinned and Asian people are not at risk for melanoma, acral lentiginous melanomas are often diagnosed in later stages when they are more difficult to treat effectively.
		A tendency to mistake the early signs of acral lentiginous melanoma for bruises or injuries to the palms, soles, or nailbeds may further delay diagnosis.
	www.melanomacenter.org /risk/race.html (220 words)

	Melanoma \| Malignant Melanoma \| Melanoma Cancer \| Nodular Melanoma
		A melanoma is a malignant tumor that originates in melanocytes, which are cells responsible for generating melanin (pigment that gives color to skin, hair and eyes and is strongest in moles).
		Lentigo maligna melanoma is considered to be an invasive form of the disease.
		Acral lentiginous melanoma is the third form of melanoma, and like the first two it spreads along the top surface before tuning invasive.
	www.e-melanoma.com (391 words)

	Dermatology Lectures Online (Site not responding. Last check: 2007-10-16)
		Acral lentiginous melanoma accounts for 7% of all melanomas.
		Acral lentiginous melanoma is more common in males than females, and usually in older people.
		Acral lentiginous melanoma is the most common form of melanoma in the skin of Asian and Black people, accounting for more than half of melanomas in these groups.
	www.dermlectures.com /LecturesWMV.cfm?lectureID=328 (157 words)

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