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Topic: Acute disseminated encephalomyelitis

	Journal,Indian Academy of Clinical Medicine (Site not responding. Last check: 2007-10-12)
		Acute disseminated encephalomyelitis is a monophasic disease and usually preceded by a viral illness or vaccination.
		Acute transverse myelitis differs clinically from myelopathy of multiple sclerosis; the former is more symmetrical, rapidly evolved, frequently having ascending involvement of the spinal cord, and initially a condition of spinal shock is present for variable period of time.
		The myelopathy is acute in onset in 50% of patients.
	www.indegene.com /jiacm/indJIACMNonCompressive.html (3303 words)

	FULMINANT ACUTE DISSEMINATED ENCEPHALOMYELITIS TREATED SUCCESSFULLY WITH IMMUNOTHERAPY (Site not responding. Last check: 2007-10-12)
		Acute disseminated encephalomyelitis (ADEM) is a widespread CNS inflammation and demyelination with an immune mediated process and usually follows an infection and immunisation.
		Acute disseminated encephalomyelitis (ADEM) is a monophasic inflammatory / demyelinating disease of the central nervous system (CNS) which is thought to be immunologically mediated and usually follows an infection due to an identifiable specific agent or non-specific upper respiratory tract infection and occasionally follows immunisation (8,9,15,16,17,21,22).
		The pathogenesis of acute viral encephalitis and postinfectious encephalomyelitis.
	www.med.ege.edu.tr /~norolbil/2000/NBD12600.html (2589 words)

	Acute disseminated encephalomyelitis. Murthy JM Neurol India
		Acute disseminated encephalomyelitis (ADEM) is an uncommon inflammatory demyelinating disease of the central nervous system.
		Acute disseminated encephalomyelitic (ADEM) is an uncommon inflammatory demyelinating disease of the central nervous system (CNS) and can be defined strictly as scattered focal or multifocal (disseminated) inflammation of brain and/or spinal cord.
		Acute hemorrhagic leukoencephalopathy is a very rare disorder and has been observed in all age groups.
	www.neurologyindia.com /article.asp?issn=0028-3886;year=2002;volume=50;issue=3;spage=238;epage=43;aulast=Murthy (3454 words)

	ACUTE DISSEMINATED ENCEPHALOMYELITIS ADEM CASE REPORTS PEDIATRIC ONCALL
		He was suspected to have an acute cerebellar ataxia due to either infarct or demyelination.
		Hence a diagnosis of recurrent acute disseminated encephalomyelitis was made.
		During the acute phase high dose steroids such as methylprednisolone is required which needs to be followed up with long-term oral steroids with slow tapering over months.
	www.pediatriconcall.com /fordoctor/casereports/adem.asp (646 words)

	Dorlands Medical Dictionary
		, and acute disseminated, postinfectious, or postvaccinal encephalitis.
		It is characterized by destruction of the white matter to the point of liquefaction; widespread necrosis of blood vessel walls leading to the formation of multiple small hemorrhages in the involved areas and the exudation of fibrin into the surrounding tissue; and cellular infiltration of the necrotic areas.
		avian encephalomyelitis,   a viral disease of chickens under six weeks old, caused by an enterovirus and marked by weakness of the legs followed by partial or complete paralysis of the legs, trembling of the head and neck, and degeneration of the neurons in the pons, medulla, and anterior horns of the spinal cord.
	www.mercksource.com /pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszSzcommonzSzdorlandszSzdorlandzSzdmd_e_07zPzhtm (3923 words)

	Revista nº 4
		Acute MS was recognized as a subtype of the disease by Otto Marburg in 1906 (11).
		Acute spinal cord lesions are characterized by extensive macrophage infiltration associated with myelin and axonal loss, and necrosis of both the gray and white matter of the spinal cord (Figure 1c).
		Chronic lesions are characterized by gliosis, cystic degeneration, cavitation, and atrophy of the spinal cord and optic nerves.
	www.fedem.org /revista/n7/patogeniaing.html (6414 words)

	[No title] (Site not responding. Last check: 2007-10-12)
		The initial presenting clinical and laboratory findings of either acute disseminated encephalomyelitis or the first attack of multiple sclerosis in the pediatric population were compared and contrasted.
		Systemic and nonfocal neurologic symptoms were more commonly evident in acute disseminated encephalomyelitis than in multiple sclerosis: fever (43% vs 6%), headache (57% vs 24%), fatigue (71% vs 29%), vomiting (57% vs 0%), and encephalopathy (71% vs 6%).
		These results suggest that acute disseminated encephalomyelitis and multiple sclerosis can be differentiated to some degree according to clinical and radiologic data at initial presentation, which is important because the long-term prognosis for childhood multiple sclerosis appears to be less favorable.
	www.mult-sclerosis.org /news/Nov2003/MedlineMSvsADEMinChildhood.html (239 words)

	Baylor Neurology Case of the Month
		Further dissection between acute disseminated encephalomyelitis and a first attack of multiple sclerosis is futile.
		Acute disseminated encephalomyelitis (ADEM) is an autoimmune, monphasic, demyelinating disease generally associated with preceding viral infection and thought to be secondary to molecular mimicry and formation of T-cell and B-cell response to endogenous proteins in the myelin layer.
		ADEM more closely mimics experimental autoimmune encephalomyelitis in that it is a monophasic illness as opposed to multiple sclerosis, which is polyphasic or progressive by definition.
	www.bcm.edu /neurol/challeng/pat32/summary.html (1099 words)

	Nat' Academies Press, Adverse Events Associated with Childhood Vaccines: Evidence Bearing on Casuality (1994)
		Also known as postinfectious neuritis or acute inflammatory demyelinating polyneuritis, it is a syndrome characterized by rapid onset of flaccid motor weakness with depression of tendon reflexes and inflammatory demyelination of peripheral nerves.
		An acute and occasionally fatal childhood syndrome of encephalopathy and fatty degeneration of the liver marked by rapid development of brain swelling and altered levels of consciousness.
		A clinical syndrome characterized by the acute onset of signs of spinal cord disease, usually involving the descending motor tracts and the ascending sensory fibers, suggesting a lesion at one level of the spinal cord.
	www.nap.edu /books/0309048958/html/335.html (2596 words)

	eMedicine - Acute Disseminated Encephalomyelitis : Article by Robert S Rust, Jr, MD (Site not responding. Last check: 2007-10-12)
		Background: Acute disseminated encephalomyelitis (ADEM) is a nonvasculitic inflammatory demyelinating condition that bears a striking clinical and pathological resemblance to multiple sclerosis (MS).
		Acute administration of very high-dose intravenous corticosteroids may possibly close the blood-brain barrier and subtend the development of edema, which may, in these fulminant cases, account for the high risk for permanent morbidity.
		Some cases are labeled as acute MS with prepubertal onset of acute encephalopathy, with mental status changes ranging from confusion to coma, seizures, and prominent pyramidal tract abnormalities (Shaw, 1987; Cole 1995).
	www.emedicine.com /NEURO/topic500.htm (8452 words)

	Acute disseminated encephalomyelitis after parenteral therapy with herbal extracts: a report of two cases -- Schwarz et ...
		Acute disseminated encephalomyelitis after parenteral therapy with herbal extracts: a report of two cases -- Schwarz et al.
		Acute disseminated encephalomyelitis (ADEM) is an unusual monophasic or multiphasic demyelinating disorder of the CNS.
		are not met because of the monophasic, acute course of the disease.
	jnnp.bmjjournals.com /cgi/content/full/69/4/516 (1625 words)

	Acute disseminated encephalomyelitis: recognition in the hands of general paediatricians -- Stonehouse et al. 88 (2): ...
		Acute disseminated encephalomyelitis, multiphasic disseminated encephalomyelitis and multiple sclerosis in children.
		Acute disseminated encephalomyelitis associated with Mycoplasma pneumonia infection.
		Acute disseminated encephalomyelitis: an unusual cause of encephalitic syndrome in childhood.
	adc.bmjjournals.com /cgi/content/full/88/2/122 (1748 words)

	Indian Pediatrics - Editorial
		ADEM was suspected by development of acute neurological deficit occurring in close temporal relationship with a viral infection or vaccination and confirmed by typical radiological appearance on MRI.
		Acute disseminated encephalomyelitis is an acute inflammatory demyelinating disease of central nervous system.
		ADEM is an acute inflammatory and demyelinating disease with a multifocal clinical presentation.
	www.indianpediatrics.net /apr2005/apr-367-371.htm (1816 words)

	Postgraduate Medicine: Symposium: Encephalitis
		Acute viral encephalitis is caused by direct viral infection of neural cells with associated perivascular inflammation and destruction of gray matter.
		Acute encephalitis is more common in the first year of life; in contrast, postinfectious encephalomyelitis is rare in infancy.
		Postinfectious encephalomyelitis, also known as acute disseminated encephalomyelitis, is characterized by perivenular inflammation and demyelination of brain tissue.
	www.postgradmed.com /issues/1998/03_98/guti.htm (2897 words)

	Encephalomyelitis (Site not responding. Last check: 2007-10-12)
		Acute disseminated encephalomyelitis: recognition in the hands of general paedia...
		Acute Disseminated Encephalomyelitis in Children -- Murthy et al.
		CDC - Eastern Equine Encephalomyelitis Virus Infection in a Horse from Californi...
	www.scienceoxygen.com /animal/211.html (182 words)

	Non-Compressive Myelopathies (Site not responding. Last check: 2007-10-12)
		The myelopathy is acute in onset in 50 percent of patients.
		Acute or subacute limb paresis with sphincter and autonomic involvement followed by optic nerve involvement are common clinical manifestations of SMON
		The inflammatory and demyelinating spinal cord disorders usually have acute or subacute onset and course; in addition, frequently, there is a good response to immunological treatment (e.g., methyl prednisolone, intravenous immunoglobulins, and immunosuppressives).
	www.indegene.com /Neu/FeatArt/indNeuFeatArt.html (3386 words)

	Post-vaccinal encephalomyelitis
		Encephalomyelitis: Inflammatory disease of the brain and spinal cord.
		This experimental allergic encephalomyelitis is mediated by sensitized lymphocytes rather than serum antibody mechanisms.
		In the postvaccinial encephalomyelitis there are also severe infiltration, demyelinization and gliosis in the opticus.
	www.whale.to /vaccines/encephalomyelitis.html (1010 words)

	Neuropathology Mini-Course
		Acute disseminated encephalomyelitis and postvaccinal encephalomyelitis are apparently identical entities, sometimes also known as postinfectious encephalomyelitis.
		The demyelination in acute disseminated encephalomyelitis occurs in a perivenular distribution.
		An experimental model of the disease may be provided by experimental allergic encephalomyelitis (EAE), a demyelinating disease produced in animals by immunizing them with neural tissue.
	www.pathology.vcu.edu /WirSelfInst/ADE.html (511 words)

	Emerging Infectious Diseases: Puumala virus infection with acute disseminated encephalomyelitis and multiorgan failure ...
		Whereas this patient had acute renal failure and acute disseminated encephalomyelitis, our patient suffered from multiorgan failure with respiratory, circulatory, and renal insufficiency, paralytic ileus, disseminated intravascular coagulation, and acute disseminated encephalo-myelitis.
		Other causes of acute disseminated encephalomyelitis such as multiple sclerosis, encephalitis caused by other infectious agents, uremic encephalitis, and hypertensive encephalitis could be ruled out.
		In summary, PUUV infection should be considered in the differential diagnosis of multiorgan failure and acute disseminated encephalomyelitis, especially in patients from PUUV-endemic areas and typical history.
	www.findarticles.com /p/articles/mi_m0GVK/is_5_9/ai_101680026 (1226 words)

	Acute Disseminated Encephalomyelitis
		We must emphasize that no sourcebook on acute disseminated encephalomyelitis should affirm that a specific diagnostic procedure or treatment discussed in a research study, patent, or doctoral dissertation is “correct” or your best option.
		While this sourcebook covers acute disseminated encephalomyelitis, your doctor, research publications, and specialists may refer to your condition using a variety of terms.
		Because of this, far less research is conducted on acute disseminated encephalomyelitis compared to other health problems afflicting larger populations, like breast cancer or heart disease.
	www.icongrouponline.com /health/Acute_Disseminated_Encephalomyelitis.html (1766 words)

	Introduction: Acute Disseminated Encephalomyelitis - WrongDiagnosis.com
		- Misdiagnosis of Underlying Causes of Acute Disseminated Encephalomyelitis
		Acute Disseminated Encephalomyelitis: Acute disseminated encephalomyelitis (ADE) is a neurological disorder characterized by inflammation of the brain and spinal cord caused by damage to the myelin sheath.
		Misdiagnosis of Underlying Causes of Acute Disseminated Encephalomyelitis
	www.wrongdiagnosis.com /a/acute_disseminated_encephalomyelitis/intro.htm (262 words)

	Final Diagnosis -- Case 102 (Site not responding. Last check: 2007-10-12)
		Acute hemorrhagic leukoencephalopathy is a hyperacute form of acute disseminated encephalomyelitis (ADEM) in which an anaphylactic-like reaction predominantly involving the white matter leads to vascular necrosis and demyelination.
		The pathologic features of acute hemorrhagic leukoencephalopathy are strikingly similar to those produced in experimental allergic encephalomyelitis when pertussis vaccine is used as an adjuvant (1).
		Both this experimental condition and the acute hemorrhagic leukoencephalopathy may be caused by deposition of circulating immune complexes within vessel walls (2).
	path.upmc.edu /cases/case102/dx.html (334 words)

	Acute Disseminated Encephalomyelitis - Thoracic Cord (Site not responding. Last check: 2007-10-12)
		The diagnosis of Acute Disseminated EncephaloMyelitis (ADEM) was considered.
		Acute disseminated encephalomyelitis in middle-aged or elderly patients.
		Araki Y, Kohmura E, Nakamura H, Tsukaguchi I. MR imaging of acute disseminating encephalomyelitis.
	home.earthlink.net /~radiologist/tf/062600.htm (189 words)

	ACUTE DISSEMINATED ENCEPHALOMYELITIS: Contact a Family - for families with disabled children: information on rare ...
		Acute Disseminated Encephalomyelitis (ADEM) accounts for up to one third of all known cases of encephalitis.
		The differential diagnoses of ADEM include acute meningitis, acute viral encephalitis and acute multiple sclerosis.
		Acute Disseminated Encephalomyelitis (ADEM) is a form of Encephalitis.
	www.cafamily.org.uk /Direct/a17.html (968 words)

	PrintPage
		A great deal of knowledge regarding their pathogenesis has accumulated over the years based on the existence of excellent animal models of the human disease, acute disseminated encephalomyelitis, the commonest neurological manifestation of an adverse immune response to vaccines.
		Experimental allergic encephalomyelitis and neuritis faithfully reproduce the pathologic alterations of the nervous system that may complicate immunizations.
		The diagnosis of acute disseminated encephalomyelitis, the commonest complication of vaccinations in both children and adult, has been aided by magnetic resonance imaging (MRI).
	www.mercola.com /display/PrintPage.aspx?docid=27657&PrintPage=yes (1154 words)

	Successful outcome with aggressive treatment of acute haemorrhagic leukoencephalitis -- MARKUS et al. 63 (4): 551 -- ...
		Acute haemorrhagic leukoencephalitis was first described as a pathological entity by Hurst in 1941.
		Acute disseminated encephalomyelitis and isolated central nervous system demyelinative syndromes.
		Computerized tomography as a diagnostic aid in acute hemorrhagic leukoencephalitis.
	www.jnnp.com /cgi/content/full/63/4/551 (796 words)

	Acute disseminated encephalomyelitis - Encyclopedia, History, Geography and Biography (Site not responding. Last check: 2007-10-12)
		Acute disseminated encephalomyelitis - Encyclopedia, History, Geography and Biography
		This page was last modified 17:56, 19 May 2005.
		This encyclopedia, history, geography and biography article about Acute disseminated encephalomyelitis contains research on
	www.arikah.net /encyclopedia/ADEM (178 words)

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