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| | eMedicine - Acute Disseminated Encephalomyelitis : Article by Robert S Rust, Jr, MD (Site not responding. Last check: 2007-10-12) |
 | | Background: Acute disseminated encephalomyelitis (ADEM) is a nonvasculitic inflammatory demyelinating condition that bears a striking clinical and pathological resemblance to multiple sclerosis (MS). |
 | | Acute administration of very high-dose intravenous corticosteroids may possibly close the blood-brain barrier and subtend the development of edema, which may, in these fulminant cases, account for the high risk for permanent morbidity. |
 | | Some cases are labeled as acute MS with prepubertal onset of acute encephalopathy, with mental status changes ranging from confusion to coma, seizures, and prominent pyramidal tract abnormalities (Shaw, 1987; Cole 1995). |
| www.emedicine.com /NEURO/topic500.htm (8452 words) |
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