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	eMedicine - Acute Lymphoblastic Leukemia : Article by Noriko Satake, MD
		Background: Acute lymphoblastic leukemia (ALL) is the most common malignancy diagnosed in children, representing nearly one third of all pediatric cancers.
		Lymphoblasts with this phenotype have a distinctive morphology, with deeply basophilic cytoplasm containing prominent vacuoles.
		The lymphoblasts are large and have basophilic cytoplasm with prominent vacuoles.
	www.emedicine.com /ped/topic2587.htm (6041 words)

	Childhood Acute Lymphoblastic Leukemia Treatment - National Cancer Institute
		Childhood acute lymphoblastic leukemia (ALL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell).
		Childhood acute lymphoblastic leukemia (also called acute lymphocytic leukemia or ALL) is a cancer of the blood and bone marrow.
		Leukemia is cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the bloodstream.
	cancer.gov /cancertopics/pdq/treatment/childALL/patient/allpages/print (6198 words)

	Leukemia & Lymphoma Society - Disease Information - Acute Lymphocytic Leukemia
		Acute lymphocytic leukemia may be called by several names, including acute lymphoid leukemia and acute lymphoblastic leukemia.
		The disease is often referred to as acute lymphoblastic leukemia because the leukemic cell that replaces the normal marrow is the (leukemic) lymphoblast.
		Other markers on the lymphoblasts that can be detected with immunophenotyping and may be useful to the physician include the common acute lymphoblastic leukemia antigen, cALLa, now called CD 10.
	www.leukemia-lymphoma.org /all_page?item_id=7049 (1290 words)

	Acute Lymphoblastic Leukemia in Children - National Cancer Institute
		Acute lymphoblastic leukemia (ALL) is a cancer of the white blood cells, the cells in the body that normally fight infections.
		In cancers such as leukemia that appear throughout the body during their earliest stages, screening does not appear to be useful.
		Most cases of leukemia are associated with changes in genes and chromosomes in the cancerous white blood cells.
	www.nci.nih.gov /newscenter/all3 (1411 words)

	FDA Expands Use for Leukemia Drug
		Leukemia is a cancer of the white blood cells.
		Acute lymphoblastic leukemia features an uncontrolled rise in lymphoblasts, which are an immature form of white blood cells called lymphocytes.
		Of the 25,000 new cases of leukemia expected in the U.S. this year, acute lymphoblastic leukemia accounts for about 2,500 cases in children and 4,000 in adults, according to the FDA.
	www.webmd.com /content/article/125/116025.htm (291 words)

	Acute Lymphoblastic Leukemia
		Acute lymphoblastic leukemia (ALL) is a leukemia derived from lymphoblasts, primitive progenitor cells originating in the bone marrow.
		However, podocalyxin was expressed by blasts in 30 (77%) of 39 cases of acute myeloid leukemia (AML), 22 (81%) of 27 cases of acute lymphoblastic leukemia (ALL), and 13 (87%) of 15 cases of cutaneous myeloid sarcoma.
		Acute lymphoblastic leukemia (ALL) in elderly patients (59 years or older) carries a poor prognosis, and this finding may be attributed to the relatively high frequency of the Philadelphia chromosome (Ph).
	www.thedoctorsdoctor.com /diseases/leukemia_all.htm (3331 words)

	Acute Lymphoblastic Leukemia - My Child Has - Children's Hospital Boston
		Acute myelogenous leukemia is a cancer of the blood in which too many granulocytes, a type of white blood cell, are produced in the marrow.
		The type of leukemia (lymphoblastic or myelogenous) is determined by where the cell is in its development when it becomes malignant, or cancerous.
		Because leukemia is cancer of the blood-forming tissue called the bone marrow, the initial symptoms are often related to abnormal bone marrow function.
	www.childrenshospital.org /az/Site759/mainpageS759P0.html (3086 words)

	VetMedCenter - Consumer - Article Details (Site not responding. Last check: 2007-10-29)
		Leukemia is the presence of abnormal white blood cells in the blood.
		Acute lymphoblastic leukemia is the form of leukemia in which the white blood cells circulating in the blood are chiefly lymphoblasts (young immature cells that mature into lymphocytes).
		Acute lymphoblastic leukemia is characterized by penetration or infiltration of excessive numbers of lymphoblasts into the bone marrow, and sometimes other organs.
	consumer.vetmedcenter.com /Consumer/display.asp?id=26108&dt=p (415 words)

	Childhood Acute Lymphoblastic Leukemia: (Site not responding. Last check: 2007-10-29)
		Reappraisal of the clinical and biologic significance of myeloid-associated antigen expression in childhood acute lymphoblastic leukemia.
		Heterogeneity of hyperdiploid (51-67) childhood acute lymphoblastic leukemia.
		Childhood acute lymphoblastic leukemia with the MLL-ENL fusion and t(11;19)(q23;p13.3) translocation.
	www.acor.org /cnet/62923.html (8418 words)

	Acute Lymphoblastic Leukemia (ALL) - patient information
		Acute lymphoblastic leukemia (ALL) is a fast-growing cancer of the white blood cells.
		Acute lymphoblastic leukemia may also be called acute lymphocytic leukemia or acute lymphoid leukemia.
		This is because leukemia cells may be returned to the patient along with his or her blood-forming cells.
	www.marrow.org /PATIENT/Undrstnd_Disease_Treat/Lrn_about_Disease/ALL/index.html (1817 words)

	Acute lymphoblastic leukaemia (ALL) in children : Cancerbackup
		Approximately 3 out of 4 of these cases are acute lymphoblastic leukaemia.
		There are four main types of leukaemia: acute lymphoblastic (ALL), acute myeloid (AML), chronic lymphocytic (CLL) and chronic myeloid (CML).
		Acute lymphoblastic leukaemia is a cancer of immature lymphocytes, called lymphoblasts or blast cells.
	www.cancerbacup.org.uk /info/child-all.htm (1595 words)

	eMedicine - Acute Lymphoblastic Leukemia : Article by Karen Seiter
		Acute lymphoblastic leukemia (ALL) is a malignant (clonal) disease of the bone marrow in which early lymphoid precursors proliferate and replace the normal hematopoietic cells of the marrow.
		In cases of acute leukemia that are MPO negative, TdT positive, the distinction between AML and ALL is made based on the analysis of flow cytometry results.
		In the United Kingdom Acute Lymphoblastic Leukemia XA study, subjects were randomized to receive early intensification with Ara-C, etoposide, thioguanine, daunorubicin, vincristine, and prednisone at 5 weeks; late intensification with the same regimen at 20 weeks; both; or neither.
	www.emedicine.com /med/topic3146.htm (8710 words)

	Childhood Leukaemia
		Children's Leukemia Foundation of Michigan (USA) CLF was founded by parents in 1952 and aims to provide compassionate personalised support for both children and adults with leukemia and other blood disorders.
		National Children's Leukemia Foundation (USA) The NCLF is a non-profit organization providing services, support, and referrals for leukemia patients and their families.The site provides details of their telephone help line, and information on various topics related to childhood leukemia.
		Leukemia and Me - a poem by Joan Fleitas RN (in Band-aides and Blackboards) a story-rhyme for children divided into 3 parts describing blood cells, about the leukemia "bullies", treatment and other issues.
	www.cancerindex.org /ccw/guide2l.htm (1771 words)

	Acute lymphoblastic leukemia - Wikipedia, the free encyclopedia
		Acute lymphoblastic leukemia (ALL), also known as acute lymphocytic leukemia, is a cancer of the white blood cells, characterised by the overproduction and continuous multiplication of malignant and immature white blood cells (referred to as lymphoblasts) in the bone marrow.
		Subtyping of the various forms of ALL is done according to the FAB (French-American-British) classification, which is used for all acute leukemias (including acute myelogenous leukemia, AML).
		The aim is to induce a lasting remission, defined as the absence of detectable cancer cells in the body (usually less than 5% blast cells on the bone marrow).
	en.wikipedia.org /wiki/Acute_lymphoblastic_leukemia (1276 words)

	Leukemia Home Page - National Cancer Institute
		Acute lymphoblastic leukemia (ALL) is a cancer of the white blood cells, the cells in the body that normally fight infections.
		Definition of leukemia: Cancer that starts in blood-forming tissue such as the bone marrow and causes large numbers of blood cells to be produced and enter the bloodstream.
		See the online booklet What You Need To Know About™ Leukemia to learn about leukemia symptoms, diagnosis, treatment, and questions to ask the doctor.
	www.cancer.gov /cancertopics/types/leukemia (250 words)

	Acute lymphoblastic leukemia definition - Cancer information on MedicineNet.com
		Acute lymphoblastic leukemia: An acute (sudden onset), rapidly progressing form of leukemia that is characterized by the presence in the blood and bone marrow of large numbers of unusually immature white blood cells destined to become lymphocytes.
		Acute lymphoblastic leukemia is also called acute lymphocytic leukemia and is abbreviated ALL (spoken not as the word "all", but as the three letters A-L-L).
		About two-thirds of acute leukemia in children with Down syndrome is ALL.
	www.medterms.com /script/main/art.asp?articlekey=13660 (519 words)

	www.patientcenters.com -- Welcome to Patient-Centered Guides Childhood Leukemia Center
		Patient-Centered Guides founding editor Nancy Keene is maintaining the four books O’Reilly published on childhood cancer through Childhood Cancer Guides, a nonprofit organization she and Catherine Woodman, M.D., created to serve the childhood cancer community by providing information, emotional support, and advocacy.
		This article describes types of relationships between parents and doctors and their effects on the care of the child with cancer.
		Dozens of veteran parents suggested questions to help newly diagnosed families understand the different types of leukemia, choose a catheter, decide whether to enroll your child in a clinical trial, and offer some basic tips on how to handle hair loss, nausea, and pain.
	www.patientcenters.com /leukemia (402 words)

	The Treatment of Adolescents and Young Adults with Acute Lymphoblastic Leukemia -- DeAngelo 2005 (1): 123 -- Hematology
		A five-drug remission induction regimen with intensive consolidation for adults with acute lymphoblastic leukemia: cancer and leukemia group B study 8811.
		Philadelphia positive acute lymphoblastic leukemia in adults: age distribution, BCR breakpoint and prognostic significance.
		Treatment of adult acute lymphoblastic leukemia (ALL): long-term follow-up of the GIMEMA ALL 0288 randomized study.
	www.asheducationbook.org /cgi/content/full/2005/1/123 (4818 words)

	Adult Acute Lymphoblastic Leukemia
		Diagnostic confusion with acute myelocytic leukemia (AML), hairy-cell leukemia, and malignant lymphoma is not uncommon.
		Because B-cell leukemias are treated according to different algorithms, it is important to specifically identify these cases prospectively by their L3 morphology, absence of TdT, and expression of surface immunoglobulin.
		Reiter A, Schrappe M, Ludwig WD, et al.: Favorable outcome of B-cell acute lymphoblastic leukemia in childhood: a report of three consecutive studies of the BFM group.
	www.meb.uni-bonn.de /cancer.gov/CDR0000062864.html (4770 words)

	Childhood acute lymphoblastic leukemia
		This treatment information summary on childhood acute lymphoblastic leukemia (ALL) is an overview of prognosis, diagnosis, classification, and patient treatment.
		The t(1;19) translocation occurs in 5% to 6% of childhood ALL, and involves fusion of the E2A gene on chromosome 19 to the PBX1 gene on chromosome 1.[24,25,54] The t(1;19) may occur as either a balanced translocation or as an unbalanced translocation and is primarily associated with pre-B ALL (cytoplasmic immunoglobulin positive).
		Ito C, Kumagai M, Manabe A, et al.: Hyperdiploid acute lymphoblastic leukemia with 51 to 65 chromosomes: a distinct biological entity with a marked propensity to undergo apoptosis.
	cancerweb.ncl.ac.uk /cancernet/100026.html (9884 words)

	Leukemia & Lymphoma Society
		This booklet provides information about acute myelogenous leukemia for patients and their families.
		Acute myelogenous leukemia may be called by several names, including acute myelocytic leukemia, acute myeloblastic leukemia, acute granulocytic leukemia or acute nonlymphocytic leukemia.
		It is distributed as a public service by The Leukemia and Lymphoma Society, with the understanding that The Leukemia and Lymphoma Society is not engaged in rendering medical or other professional services.
	www.leukemia.org /all_mat_toc.adp?item_id=3113&cat_id=1204 (207 words)

	Acute Lymphoblastic Leukemia (Site not responding. Last check: 2007-10-29)
		Acute lymphoblastic leukaemia is a rare (1/100000 per year) disease characterized by a malignant proliferation of lymphoblasts.
		It is mostly a childhood disease, with a peak incidence at age 3.
		It is usally diagnosed by examination of blood and bone marrow samples.
	www.mcl.tulane.edu /classware/pathology/Krause/Leukemias/ALL/ALL.html (86 words)

	NEJM -- Acute Lymphoblastic Leukemia
		CD10- pre-B acute lymphoblastic leukemia (ALL) is a distinct high-risk subgroup of adult ALL associated with a high frequency of MLL aberrations: results of the German Multicenter Trials for Adult ALL (GMALL).
		DeAngelo, D. The Treatment of Adolescents and Young Adults with Acute Lymphoblastic Leukemia.
		Armstrong, S. Leukemia gene expression: MLL rearrangements in AML and ALL.
	content.nejm.org /cgi/content/short/350/15/1535 (1077 words)

	Acute Lymphoblastic Leukemia -- Hoelzer et al. 2002 (1): 162 -- Hematology
		leukemia related to the use of epipodophyllotoxins are characterized
		with therapy-related leukemia overexpress the genes that encode
		Chromosome aberrations in acute lymphoblastic leukemia (ALL) as (reverse transcriptase) polymerase chain reaction [(RT-)PCR] targets for minimal residual disease (MRD) detection.
	www.asheducationbook.org /cgi/content/full/2002/1/162 (9525 words)

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