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Topic: Acute myelocytic leukemia


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AML

In the News (Sat 10 Jan 09)

  
  Acute myeloid leukemia - Wikipedia, the free encyclopedia
Acute myelogenous leukemia (AML), also known as acute myeloid leukemia, is a cancer of the myeloid line of blood cells.
Acute leukemias of ambiguous lineage (also known as mixed phenotype acute leukemia) occur when the leukemic cells can not be classified as either myeloid or lymphoid cells or where both types of cells are present.
Because acute promyelocytic leukemia has the highest curability and has a unique form of treatment, it is important to establish or exclude the diagnosis of this subtype of leukemia.
en.wikipedia.org /wiki/Acute_myelocytic_leukemia   (1310 words)

  
 Leukemia   (Site not responding. Last check: 2007-10-23)
Leukemia is a malignant proliferation of cells arising in a single deranged stem cell and resulting in the overgrowth of certain cell lines.
Acute leukemia presents microscopically with the majority of cellsas blasts, severe anemia, and markedly decreased platelets.
This is a subclassification and represents 10 % of all acute myelocytic leukemia.
www.gomcl.com /hema/leukemia   (406 words)

  
 Acute Lymphocytic Leukemia Cancer.
Acute lymphocytic leukemia is the principal type of leukemia that affects children.
Although acute myelocytic leukemia, chronic lymphocytic leukemia and chronic myelocytic leukemia are occasionally seen in children, they are primarily diseases which appear in adults.
Leukemia is a generalized disorder of blood cell production in which abnormal white blood cells accumulate in the blood and bone marrow.
www.cancer-info.com /lymphleuk.htm   (2541 words)

  
 Acute leukemia
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www.cancer-facts.info /cancerc/acuteleukemia.php   (437 words)

  
 Acute Myelocytic Leukemia: Leukemias: Merck Manual Home Edition
Acute myelocytic (myeloid, myelogenous, myeloblastic, myelomonocytic) leukemia is a life-threatening disease in which the cells that normally develop into neutrophils, basophils, eosinophils, and monocytes become cancerous and rapidly replace normal cells in the bone marrow.
Acute myelocytic leukemia (AML) is the most common type of leukemia among adults, although it affects people of all ages.
Once AML is in remission, the person usually receives a few courses of additional chemotherapy (consolidation chemotherapy) a few weeks or months after the initial treatment to help ensure that as many leukemia cells as possible are destroyed.
www.merck.com /mmhe/sec14/ch176/ch176c.html   (730 words)

  
 Cancer - Acute Leukemia   (Site not responding. Last check: 2007-10-23)
Leukemia* is a malignant disease (cancer) of the bone marrow and blood.
Leukemia is a malignancy or cancer of the bone marrow.
Acute leukemia is a rapidly progressing disease that results in the accumulation of immature, functionless cells in the marrow and blood.
www.aftercancer.org /leukemia/acute_leukemia   (898 words)

  
 Pathology
As with all acute leukemias, acute lymphoblastic leukemia is characterized by proliferation of blasts (lymphoblasts) in the bone marrow.
Acute myelocytic leukemia, M1 Acute myelocytic leukemia, M2 Acute promyelocytic leukemia, M3 Acute myelocytic leukemia, M4 Acute myelocytic leukemia, M5 30% blasts and >10% cells with maturation (promyelocytes - polymorphonuclear leukocytes) are seen.
Acute myelocytic leukemia, M1 Acute myelocytic leukemia, M2 Acute promyelocytic leukemia, M3 Acute myelomonocytic leukemia, M4 Acute monocytic leukemia, M5 55% large blasts with folded nuclei and large nucleoli accompanied by numerous promonocytes, monocytes and a few dysplastic myelocytes indicates a monoblastic leukemia.
www.med-ed.virginia.edu /courses/path/innes/wcd/lymphoid.cfm   (1521 words)

  
 Acute Leukemia
Leukemia is usually a cancer of the white blood cells.
Acute leukemia is likely if the "Philadelphia Chromosome" is seen, as it is in 10% of children and 30% of adults with AML or ALL.
Acute leukemias are cancers of blood cells, and are one of two basic types.
www.canceranswers.com /Acute.Leukemia.html   (2763 words)

  
 Info   (Site not responding. Last check: 2007-10-23)
Azurophilic granules indicate the presence of a myelocytic leukemia.
Like the acute lymphatic leukemias the acute myelocytic leukemias are classified by FAB (F=French, A=American, B=British) based on their morphology.
M2 = myelocytic leukemia with maturation: The blasts are large with ample cytoplasm with azurophilic granules.
www.aum.iawf.unibe.ch /HemoSurf/Demo_E/Info/AML.htm   (367 words)

  
 Adult acute myeloid leukemia
Leukemias that express the progenitor cell antigen CD34 and/or the P-glycoprotein (MDR1 gene product) have an inferior outcome.[6-8] Expression of the bcl-2 oncoprotein, which inhibits programmed cell death, has been shown to predict poor survival.[9] Cytogenetic analysis provides some of the strongest prognostic information available and is helpful in patients with newly diagnosed AML.
Patients with AML that is characterized by deletions of the long arms or monosomies of chromosomes 5 or 7; by translocations or inversions of chromosome 3, t(6;9), t(9;22); or by abnormalities of chromosome 11q23 have particularly poor prognoses with chemotherapy.
Acute myeloid leukemia (AML) is classified morphologically according to the French-American-British criteria by the degree of differentiation along different cell lines and the extent of cell maturation.[1-3]
www.meds.com /pdq/myeloid_pro.html   (7255 words)

  
 Hematology Acute myeloblastic leukemia   (Site not responding. Last check: 2007-10-23)
Acute myelocytic leukemia (AML), is the most common leukemia in children less than 1 year of age.
It is rare in older children and adolescents, but a second peak of incidence occurs among adults 40 years of age.
Enlarged spleen is seen in 50% of all AML patients, but lymph node enlargement is rare.
www.wadsworth.org /chemheme/heme/microscope/aml.htm   (113 words)

  
 Acute leukemia
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www.cancer-facts.info /cancerc/acuteleukemia.html   (495 words)

  
 eMedicine - Acute Myelocytic Leukemia : Article by Mark E Weinblatt, MD   (Site not responding. Last check: 2007-10-23)
Background: Acute myelocytic leukemia (AML) is a group of malignant disorders characterized by the replacement of normal bone marrow with abnormal, primitive hematopoietic cells.
Pathophysiology: Acute leukemia is believed to begin in a single somatic hematopoietic progenitor that transforms to a cell incapable of normal differentiation.
Disease-free survival of patients with acute promyelocytic leukemia is approximately 75%.
www.emedicine.com /ped/topic1301.htm   (7247 words)

  
 Cancer - Aml Leukemia   (Site not responding. Last check: 2007-10-23)
Acute leukemia is a disease of the leukocytes and their precursors 0.
Adult acute myeloid leukemia (AML) is a disease in which cancer (malignant) cells are found in the blood and bone marrow.
Acute myelogenous leukemia (AML) is the most frequently reported form of leukemia in adults, and approximately 10,100 new cases are anticipated in 1999.
www.aftercancer.org /leukemia/aml_leukemia   (887 words)

  
 Medical Dictionary: Acute myelocytic leukemia - WrongDiagnosis.com
Acute myelocytic leukemia: A malignant cancer of blood-forming tissues resulting in a high number of immature leukocytes.
Acute myelocytic leukemia is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH).
This means that Acute myelocytic leukemia, or a subtype of Acute myelocytic leukemia, affects less than 200,000 people in the US population.
www.wrongdiagnosis.com /medical/acute_myelocytic_leukemia.htm   (273 words)

  
 eMedicine - Acute Myelogenous Leukemia : Article by Karen Seiter, MD
Background: Acute myelogenous leukemia (AML) is a malignant disease of the bone marrow in which hematopoietic precursors are arrested in an early stage of development.
For example, the cumulative incidence of acute leukemia in patients with breast cancer who were treated with doxorubicin and cyclophosphamide as adjuvant therapy was 0.2-1.0% at 5 years.
Acute promyelocytic leukemia (APL), also known as M3, is the most common subtype of AML associated with DIC.
www.emedicine.com /med/topic34.htm   (8097 words)

  
 Adult acute myeloid leukemia
These cytogenetic subgroups predict clinical outcome in elderly patients with AML as well as in younger patients.[10] The fusion genes formed in t(8;21) and inv(16) can be detected by reverse-transcriptase polymerase chain reaction (RT-PCR), which will indicate the presence of these genetic alterations in some patients in whom standard cytogenetics was technically inadequate.
Buchner T, Hiddemann W, Wormann B, et al.: Double induction strategy for acute myeloid leukemia: the effect of high-dose cytarabine with mitoxantrone instead of standard-dose cytarabine with daunorubicin and 6-thioguanine: a randomized trial by the German AML Cooperative Group.
However, even with allogeneic stem cell transplantation, the outcome for high-risk patients is poor (5-year disease-free survival of 8% to 30% for patients with treatment-related leukemia or myelodysplasia).[33] The efficacy of autologous stem cell transplantation in the poor-risk group has not been reported to date but is the subject of active clinical trials.
cancerweb.ncl.ac.uk /cancernet/101029.html   (8110 words)

  
 Acute Myelocytic Leukemia by Benzene-leukemia-lawfirm.com
Related terms include burkett lymphoma, jeffrey bornstein and leukemia, properties of benzene, lymphocytes nutrition, and symptoms of non hodgkins lymphoma.
Leukemia is cancer of the blood-forming tissues, the bone marrow, lymph nodes and the spleen.
Acute myelocytic leukemia related phrases are on Benzene-leukemia-lawfirm.com.
www.benzene-leukemia-lawfirm.com /acute_myelocytic_leukemia_c.html   (515 words)

  
 Adult Acute Lymphoblastic Leukemia
Diagnostic confusion with acute myelocytic leukemia (AML), hairy-cell leukemia, and malignant lymphoma is not uncommon.
Because B-cell leukemias are treated according to different algorithms, it is important to specifically identify these cases prospectively by their L3 morphology, absence of TdT, and expression of surface immunoglobulin.
Paciucci PA, Keaveney C, Cuttner J, et al.: Mitoxantrone, vincristine, and prednisone in adults with relapsed or primarily refractory acute lymphocytic leukemia and terminal deoxynucleotidyl transferase positive blastic phase chronic myelocytic leukemia.
www.meb.uni-bonn.de /cancer.gov/CDR0000062864.html   (4770 words)

  
 myloid leukemia   (Site not responding. Last check: 2007-10-23)
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www.burke-eisner.com /Benzene/ben1/myloid-leukemia.html   (146 words)

  
 Acute myelocytic leukemia and prior allergies.
The relationship between prior allergies and adult acute myelocytic leukemia was investigated in a population-based case-control study.
Based on data from personal interviews of 98 cases and 133 controls, a history of any type of allergy was associated with a significantly decreased risk of acute myelocytic leukemia (OR = 0.35, 95% CI = 0.20-0.60).
Risk declined with the total number of specific allergies reported (p less than 0.001), and was reduced in relation to a history of prior asthma, eczema and hives.
www.aegis.com /aidsline/1990/feb/M9020467.html   (332 words)

  
 Autologous Stem Cell Transplantation in Acute Myelocytic Leukemia -- Gorin 92 (4): 1073 -- Blood
IN THE PAST 30 YEARS, the treatment of acute myelocytic leukemia (AML) has considerably evolved and improved.
in relapse incidence with immunomodulation or leukemia vaccines
role of autologous bone marrow transplantation in acute leukemia.
www.bloodjournal.org /cgi/content/full/92/4/1073   (8988 words)

  
 Leukemia, acute myeloblastic   (Site not responding. Last check: 2007-10-23)
An acute non-lymphoblastic leukemia occurs at all ages and is the more common leukemia among adults.
Usually associated with irradiation as a causative agent and occurring as a second malignancy following cancer chemotherapy.
205.00 myeloid leukemia, acute, without mention of remission
www.5mcc.com /Assets/SUMMARY/TP0533.html   (53 words)

  
 MedlinePlus Medical Encyclopedia: Acute myelocytic leukemia - microscopic view   (Site not responding. Last check: 2007-10-23)
This microscope image shows AML cells (acute myeloblastic leukemia; also referred to as ANLL, acute nonlymphocytic leukemia).
Certain internal cell structures are typical of AML.
These include prominent nucleoli (red arrows) and cytoplasmic granules (grainy structures inside the cell which indicate some degree of cell maturation--fl arrow).
www.nlm.nih.gov /medlineplus/ency/imagepages/1439.htm   (140 words)

  
 Acute Myelocytic Leukemia at Benzene-leukemia-lawfirm.com
Other related phrases include lymphoma pictures, ethyl benzene isomerization technology, nonhodgkins lymphoma symptoms, benzene ppm conversion, and leukemia downs syndrome.
Other related terms are benzene ppm conversion, lymphoma pictures, nonhodgkins lymphoma symptoms, ethyl benzene isomerization technology, and leukemia downs syndrome.
Related terms are lymphoma pictures, nonhodgkins lymphoma symptoms, ethyl benzene isomerization technology, benzene ppm conversion, and leukemia downs syndrome.
www.benzene-leukemia-lawfirm.com /acute_myelocytic_leukemia_d.html   (661 words)

  
 Energy Citations Database (ECD) - Energy and Energy-Related Bibliographic Citations
Energy Citations Database (ECD) Document #6767893 - Acute myelocytic leukemia after exposure to asbestos
Availability information may be found in the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or via the "Full-text Availability" link.
560300 -- Chemicals Metabolism & Toxicology ;550900 -- Pathology; ASBESTOS-- CARCINOGENESIS;MYELOID LEUKEMIA-- PATHOGENESIS; BONE MARROW;ENVIRONMENTAL EXPOSURE;PATIENTS
www.osti.gov /energycitations/product.biblio.jsp?osti_id=6767893   (103 words)

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