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Topic: Acute myelomonocytic leukemia

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	Atlas Of Acute Leukemia (ALL, AML)
		Acute leukemia is closely related to erythroleukemia, a condition intermediate between acute erythremia and acute leukemia erythremia <— erythroleukemia —> myeloblastic leukemia.
		Acute eosinophilic leukemia is diagnosed by examination of the bone marrow, since eosinophils usually are not increased in the peripheral blood.
		Acute basophilic leukemia is evidenced by an extreme increase in the basophilic granulated cells of granulocytopoiesis.
	www.meds.com /leukemia/atlas/acute_leukemia.html (815 words)

	Nikon MicroscopyU: Human Pathology Digital Image Gallery - Myelomonocytic Leukemia (Acute)
		Leukemias are a group of diseases characterized by an abnormal proliferation of white blood cells.
		Acute myelomonocytic leukemia, which is designated M4, is one of the most common of the eight types, accounting for about one-fourth of all cases of acute myelogenous leukemia.
		Myelomonocytic Leukemia at 20x Magnification - Overall the cure rate for myelomonocytic leukemia patients less than 60 years of age is about 30 percent, although certain subsets of individuals tend to fare much better or worse.
	www.microscopyu.com /galleries/pathology/acutemyelomonocyticleukemia.html (460 words)

	Cutaneous Vasculitis as the Initial Manifestation in Acute Myelomonocytic Leukemia -- Bourantas et al. 121 (12): 942 -- ...
		Acute myelomonocytic leukemia is a neoplastic disorder of the
		the diagnosis of acute myelomonocytic leukemia by an interval
		Proposals for the classification of the acute leukaemias.
	www.annals.org /cgi/content/full/121/12/942 (1202 words)

	Adult Acute Myeloid Leukemia: (Site not responding. Last check: 2007-10-29)
		AML with the translocation t(8;21)(q22;q22) (FAB classification M2) is 1 of the most common genetic aberrations in AML and accounts for 5% to 12% of cases of AML and one third of karyotypically abnormal cases of acute myeloblastic leukemia with maturation.
		Acute myelomonocytic leukemia (AMML) is characterized by the proliferation of neutrophil and monocyte precursors.
		The 2 subtypes of the acute erythroid leukemias, erythroleukemia and pure erythroid leukemia, are characterized by a predominant erythroid population and, in the case of erythroleukemia, the presence of a significant myeloid component.
	www.acor.org /cnet/62869.html (8993 words)

	Acute Myeloid Leukemia (AML)
		Acute myeloid leukemia (AML), also known as acute myelogenous or acute myeloblastic leukemia, is a type of cancer that starts from cells that normally develop into blood cells.
		AML is caused by genetic damage to these developing cells in the bone marrow.
		Acute myelogenous leukemia (AML) is the most common form of leukemia with more than 10,000 people diagnosed each year, according to National Cancer Institute estimates.
	www.fhcrc.org /research/diseases/aml (827 words)

	Acute Myeloid Leukemia
		Acute myeloid leukemia (AML) with inv(16)(p13q22), also known as M4Eo, is a distinct type of AML with a favorable prognosis associated with abnormal bone marrow eosinophils.
		Acute myelogenous leukemia with t(8;21) is a distinct clinicopathologic entity in which the malignant myeloblasts display a characteristic pattern of surface antigen expression.
		Acute promyelocytic leukemia (APL) should be distinguished from other subtypes of acute myeloid leukemia (AML) because of the increased risk of disseminated intravascular coagulation (DIC) and its response to arsenic compounds and retinoids.
	www.thedoctorsdoctor.com /diseases/leukemia_aml.htm (6859 words)

	M. D. Anderson Cancer Center - What is Leukemia
		Leukemia is cancer of blood-forming tissue such as bone marrow.
		There is no increased occurrence of leukemia among people such as friends, family and caregivers who have close contact with leukemia patients.
		The diagnosis of leukemia is based on the results of both blood and bone marrow tests such as bone marrow aspiration and bone marrow biopsy.
	www.mdanderson.org /departments/leukemia/dIndex.cfm?pn=A8426C6A-D0FF-11D4-80FD00508B603A14 (1022 words)

	Leukemia & Lymphoma Society
		CMML is more rapidly progressive than "typical" chronic myelogenous leukemia and less rapidly progressive than a type of acute leukemia known as acute myelomonocytic leukemia.
		This leukemia is part of the spectrum of myelogenous leukemias that may have findings that simulate typical chronic myelogenous leukemia (CML) such as anemia, high white cell count and enlargement of the spleen.
		Most patients with chronic myelomonocytic leukemia (CMML) are over 50 years of age and about 75 percent of cases are over 60 years of age at the time of diagnosis.
	www.leukemia-lymphoma.org /all_mat_toc.adp?item_id=69974 (1036 words)

	Acute Myelocytic Leukemia - A Great Resource of Information (Site not responding. Last check: 2007-10-29)
		N.Fusion of ETV6 to neurotrophin- 3 receptor TRKC in acute myeloid leukemia with t(12;15)(p13;q25).Blood,93:1355- 1363,1999 71.
		Diagnostic confusion with acute myelocytic leukemia (AML), hairy-cell leukemia, and malignant lymphoma is not uncommon.
		acute kidney failure acute leukemia acute lymphoblastic leukemia acute lymphocytic leukemia acute myelocytic leukemia acute myeloid leukemia acute organic brain syndrome acute pyelonephritis acute...
	www.lymphomabase.com /acutemyelocyticleukemia (1458 words)

	eMedicine - Acute Myelogenous Leukemia : Article Excerpt by: Karen Seiter, MD
		Background: Acute myelogenous leukemia (AML) is a malignant disease of the bone marrow in which hematopoietic precursors are arrested in an early stage of development.
		Most AML subtypes are distinguished from other related blood disorders by the presence of more than 20% blasts in the bone marrow.
		AML is more common in whites than in other populations.
	www.emedicine.com /med/byname/acute-myelogenous-leukemia.htm (376 words)

	Latest Acute Leukemia (ALL & AML) Treatments
		Leukemia is a cancer of the white blood cells and bone marrow.
		In acute leukemia, immature, functionless cells accumulate in the marrow and blood.
		Acute myelogenous leukemia (AML) is the most common leukemia in adults with some 10,500 new cases annually.
	www.cancergroup.com /em33.html (396 words)

	Gingival Hyperplasia Complicating Acute Myelomonocytic Leukemia
		Given our concern about possible acute leukemia, which was substantiated by a complete blood count with differential, a bone marrow biopsy was performed and the nodule was excised.
		Gingival hyperplasia is most commonly seen with the AML subtypes acute monocytic leukemia (M5) (66.7%), acute myelomonocytic leukemia (M4) (18.5%), and acute myelocytic leukemia (M1, M2) (3.7%).
		Leukemia cell gingival infiltrate is not observed in edentulous individuals, suggesting that local irritation and trauma associated with the presence of teeth may play a role in the pathogenesis of this abnormality.
	www.cda-adc.ca /jadc/vol-66/issue-2/78.html (1059 words)

	Adult acute myeloid leukemia
		Leukemias that express the progenitor cell antigen CD34 and/or the P-glycoprotein (MDR1 gene product) have an inferior outcome.[6-8] Expression of the bcl-2 oncoprotein, which inhibits programmed cell death, has been shown to predict poor survival.[9] Cytogenetic analysis provides some of the strongest prognostic information available and is helpful in patients with newly diagnosed AML.
		Acute myeloid leukemia (AML) is classified morphologically according to the French-American-British criteria by the degree of differentiation along different cell lines and the extent of cell maturation.[1-3]
		Adult AML in remission is defined as a normal peripheral blood cell count and normocellular marrow with less than 5% blasts in the marrow, and no signs or symptoms of the disease.
	www.meds.com /pdq/myeloid_pro.html (7255 words)

	eMedicine - Acute Myelogenous Leukemia : Article by Karen Seiter, MD
		For example, the cumulative incidence of acute leukemia in patients with breast cancer who were treated with doxorubicin and cyclophosphamide as adjuvant therapy was 0.2-1.0% at 5 years.
		Acute promyelocytic leukemia (APL), also known as M3, is the most common subtype of AML associated with DIC.
		However, the median age of patients with AML is 65 years; therefore, only a small percentage of patients with AML are candidates for such aggressive therapy.
	www.emedicine.com /med/topic34.htm (8097 words)

	Acute Myeloid Leukemia (AML) - CancerIndex
		Acute myeloid leukemia (AML) is a disease in which too many immature granulocytes (a type of white blood cell) are found in the blood and bone marrow.
		There are a number of subtypes of AML including acute myeloblastic leukemia, acute promyelocytic leukemia, acute monocytic leukemia, acute myelomonocytic leukemia, erythroleukemia, and acute megakaryoblastic leukemia.
		Case study: Acute myelogenous leukemia (FAB-M2)+ chronic lymphocytic leukemia in a 68 yr F (Department of Pathology, University of Pittsburgh)
	www.cancerindex.org /clinks3x.htm (211 words)

	Medical Dictionary: Acute myelomonocytic leukemia - WrongDiagnosis.com - WrongDiagnosis.com
		Acute myelomonocytic leukemia is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH).
		This means that Acute myelomonocytic leukemia, or a subtype of Acute myelomonocytic leukemia, affects less than 200,000 people in the US population.
		They list Acute myelomonocytic leukemia as a "rare disease".
	www.wrongdiagnosis.com /medical/acute_myelomonocytic_leukemia_printer.htm (186 words)

	Adult acute myeloid leukemia
		These cytogenetic subgroups predict clinical outcome in elderly patients with AML as well as in younger patients.[10] The fusion genes formed in t(8;21) and inv(16) can be detected by reverse-transcriptase polymerase chain reaction (RT-PCR), which will indicate the presence of these genetic alterations in some patients in whom standard cytogenetics was technically inadequate.
		Buchner T, Hiddemann W, Wormann B, et al.: Double induction strategy for acute myeloid leukemia: the effect of high-dose cytarabine with mitoxantrone instead of standard-dose cytarabine with daunorubicin and 6-thioguanine: a randomized trial by the German AML Cooperative Group.
		However, even with allogeneic stem cell transplantation, the outcome for high-risk patients is poor (5-year disease-free survival of 8% to 30% for patients with treatment-related leukemia or myelodysplasia).[33] The efficacy of autologous stem cell transplantation in the poor-risk group has not been reported to date but is the subject of active clinical trials.
	cancerweb.ncl.ac.uk /cancernet/101029.html (8110 words)

	DSMZ
		PubMed ID Matsuo Y, Drexler HG, Sugimoto A, Harashima A, Okochi A, Kojima K, Orita K: Novel B-cell acute lymphoblastic leukemia sister cell lines BALM 19-23 and BALM-26 with interclonal proliferative and phenotypic heterogeneity derived from a patient with hypercalcemia.
		Graf G, Zaborski M, Quentmeier H, Drexler HG: Phorbol ester PMA induces expression of the thrombopoietin receptor MPL in leukemia cells.
		PubMed ID Steube KG, Drexler HG: Differentiation and growth modulation of myeloid leukemia cells by the protein kinase C activating agent Bryostatin-1.
	www.dsmz.de /human_and_animal_cell_lines/main.php?contentleft_id=7 (7669 words)

	Cancer and biopsy information at HealthCentersOnline - CancerHealthOnline
		Acute Lymphoblastic Leukemia in Children (Acute Lymphocytic Leukemia in Children)
		ALL in Children (Acute Lymphocytic Leukemia in Children)
		ALL Leukemia in Children (Acute Lymphocytic Leukemia in Children)
	cancer.healthcentersonline.com /encyclopedia (239 words)

	Myeloperoxidase in acute myelomonocytic leukemia (Site not responding. Last check: 2007-10-29)
		The FAB investigators recommend two cytochemical tests for the diagnosis of all new cases of acute leukemia.
		These recommended tests are (1) myeloperoxidase activity or Sudan fl staining, which are positive in nearly all cases of myelocytic leukemia, and (2) esterase activity for identifying monocytes.
		The latter assay recommended is naphthol AS-D acetate substrate and fast blue or fast blue BB salt for coupling the liberated product to form a colored compound.
	www.academic.marist.edu /~jzmz/topics/erythroleukemia/myelomono18.html (131 words)

	PROGENETIX CGH database: Acute myelomonocytic leukemia (Site not responding. Last check: 2007-10-29)
		t(11;16) positive, treatment related leukemia (t-MDS/t-AML (M4) to t-T-ALL)
		Progenetix collects information about changes in the chromosomes (chromosomal rearrangements) and genomic composition of cancer and leukemia cases.
		It consists of a compilation of published data from Comparative Genomic Hybridization (CGH), array CGH and matrix CGH (aCGH) experiments, as well as from some studies using Metaphase analysis (Giemsa banding, SKY, MFISH).
	www.progenetix.de /~pgscripts/progenetix/I98673/casetable.html (376 words)

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