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Topic: Acute thrombocytopenic purpura


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In the News (Sat 10 Jan 09)

  
  Thrombotic Thromboctyopenic Purpura
Thrombotic thrombocytopenic purpura (TTP) is a rare blood condition characterized by the formation of small clots (thrombi) within the circulation, which results in the consumption of platelets and thus a low platelet count (thrombocytopenia).
Thereafter, the emphasis of reports on Thrombotic Thrombocytopenic Purpura was almost uniformly on the triad, consisting of thrombocytopenia purpura, hemolytic anemia, and varying neurologic manifestations.
Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic Syndrome were once thought to represent opposite ends of the spectrum of the same disease process and are classified by some as thrombotic microangiopathy (TMA).
www.about-ttp.com   (823 words)

  
  ITP - Primary Care Consultants
Purpura refers to the purplish- looking areas of the skin and mucous membranes (such as the lining of the mouth) where bleeding has occurred as a result of decreased platelet.
Thrombocytopenic purpura is considered chronic when it has lasted more than 6 months.
The treatment of idiopathic thrombocytopenic purpura is determined by the severity of the symptoms.
www.pccdocs.com /patientresources/patient_pamphlets/itp.htm   (645 words)

  
 Howstuffworks "Purpura: A profile of a Bleeding Disorder"
The term purpura refers to a group of bleeding disorders characterized by purplish or brownish-red discolorations, easily visible through the skin's outer layer, that are caused by hemorrhaging (internal bleeding) into the tissues.
Thrombocytopenic purpura is a disorder in which the number of platelets (the tiny elements in the blood that are vital to clotting) is decreased, whether because of a primary disease or as a consequence of another blood disorder.
Purpura in the elderly is often due to the fragility of their skin.
health.howstuffworks.com /define-purpura.htm   (514 words)

  
 Intravenous Immunoglobulin Is Effective Therapy for Acute Idiopathic Thrombocytopenic Purpura
The main reason for treating children with acute ITP is the prevention of intracranial hemorrhage (ICH), a complication that occurs in 1% of affected children.
Given that acute ITP in childhood is usually self-limited disease, the inclusion of a no-therapy group in this study is helpful (and rather unique among other published studies).
A prospective, randomized trial of high-dose intravenous immune globulin G therapy, oral prednisone therapy, and no therapy in childhood acute immune thrombocytopenic purpura.
www.med.umich.edu /pediatrics/ebm/cats/itp.htm   (480 words)

  
 Thrombocytopenia purpura
Thrombocytopenic purpura following vaccination with attenuated measles virus.
Jonville-Bera AP, et al Thrombocytopenic purpura after measles, mumps and rubella vaccination: a retrospective survey by the French regional pharmacovigilance centres and pasteur-merieux serums et vaccins.
Immune thrombocytopenic purpura after recombinant hepatitis B vaccine: retrospective study of seven cases.
www.whale.to /vaccines/thrombocytopenia_purpura.htm   (465 words)

  
 What Is Idiopathic Thrombocytopenic Purpura?
Idiopathic thrombocytopenic purpura (ITP) is a bleeding disorder in which the blood does not clot as it should.
Thrombocytopenic (throm-bo-cy-toe-PEE-nick) means there is a lower-than-normal number of platelets in the blood.
Because "idiopathic" means "of unknown cause," a better name for most cases of ITP is immune thrombocytopenic purpura.
www.nhlbi.nih.gov /health/dci/Diseases/Itp/ITP_WhatIs.html   (464 words)

  
 NEJM -- Antibodies to von Willebrand Factor-Cleaving Protease in Acute Thrombotic Thrombocytopenic Purpura
NEJM -- Antibodies to von Willebrand Factor-Cleaving Protease in Acute Thrombotic Thrombocytopenic Purpura
Antibodies to von Willebrand Factor–Cleaving Protease in Acute Thrombotic Thrombocytopenic Purpura
Relapsing catastrophic antiphospholipid antibody syndrome: a mimic for thrombotic thrombocytopenic purpura?.
content.nejm.org /cgi/content/abstract/339/22/1585   (2746 words)

  
 The Turkish Journal of Pediatrics   (Site not responding. Last check: 2007-09-17)
The diagnosis of acute poststreptococcal glomerulonephritis was based upon the evidence of previous sore throat, hypocomplementemia and increased antistreptolysin O titer.
In typical cases the diagnosis is easily established upon the history of antecedent streptococcal infection, acute onset of nephritic signs, transitory depression of C3 complement level, isolation of group A beta hemolytic streptococci from throat swab or pyoderma, and significant titer of streptococcal antibodies[1].
Idiopathic thrombocytopenic purpura (ITP) is a disorder in which platelets, sensitised by autoantibodies, are destroyed by the reticuloendothelial system.
tjp.dergisi.org /text.php3?id=61   (1675 words)

  
 Acute immune thrombocytopenic purpura: What do we do when things go well?
Immune thrombocytopenic purpura (ITP) is among the more common hematological disorders observed by both paediatric hematologists and general paediatricians.
The Children’s Hospital of Eastern Ontario, Ottawa, which provides tertiary care to the Ottawa/Hull region with a population of approximately one million, admitted 15 children with a new diagnosis of ITP from December 1, 2000 to November 30, 2001, roughly eight admissions/100,000 children annually (1).
The initial management of a child presenting with acute ITP is fraught with many questions and very few answers.
www.pulsus.com /Paeds/07_06/klaa_ed.htm   (1079 words)

  
 Information about Idiopathic thrombocytopenic Purpura
Idiopathic thrombocytopenic purpura is a bleeding disorder in which the blood does not clot properly.
The most common symptom of idiopathic thrombocytopenic purpura is bleeding, bruising, and tiny red dots on the skin or mucous membranes.
Acute idiopathic thrombocytopenic purpura often goes away on its own within a few weeks or months and does not return.
www.mamashealth.com /blood/itp.asp   (337 words)

  
 A Birth-Control Pill for Men?
ATP acts as a kind of storage battery for energy, releasing it to body tissues as it is needed.
Researchers had previously found that certain smooth muscle tissues such as the vas deferens, the duct through which matured sperm are carried into the penis, have special "receptors" that accept ATP molecules in the same way that a door lock accepts a key.
receptor for ATP was missing, the scientists bred a strain of mice with a genetic mutation that caused the receptor to be deleted.
www.webmd.com /content/article/23/1728_53943.htm   (584 words)

  
 Idiopathic Thrombocytopenic Purpura
IDIOPATHIC thrombocytopenic purpura (ITP, also known as primary immune thrombocytopenic purpura) is a hematologic disorder for which appropriate diagnostic and treatment strategies are uncertain.
In the absence of evidence, the opinion of the panel was that hospitalization is appropriate for a child with severe, life-threatening bleeding, regardless of the platelet count (9.0, A), and for a child with a platelet count of <20,000 and mucous membrane bleeding that may require clinical intervention (8.2, C).
Acute and severe thrombocytopenia may be a manifestation of bacteremia or viral infection; HIV infection is commonly associated with thrombocytopenia.104 Acute anemia, neurologic, or renal abnormalities may suggest thrombotic thrombocytopenic purpura.
www.vaccinetruth.org /idiopathic_thrombocytopenic_purpura.htm   (15213 words)

  
 Immune Thrombocytopenic Purpura
“Purpura” is a purplish-looking areas of the skin and mucous membranes, such as the lining of the mouth, where bleeding has occurred as a result of decreased platelets.
Acute, or temporary, thrombocytopenic purpura is the most common in young children.
Thrombocytopenic purpura is considered chronic when it has lasted more than six months.
members.tripod.com /vs8/itp.htm   (664 words)

  
 Measles (Rubeola) Glossary of Terms with Definitions on MedicineNet.com
Acute often also connotes an illness that is of short duration, rapidly progressive, and in need of urgent care.
Acute respiratory disease (ARD), a disorder first recognized among military recruits during World War II, can be caused by adenovirus infections under conditions of crowding and stress.
Paramyxovirus: One of a group of RNA viruses that are responsible predominantly for acute respiratory diseases and are usually transmitted in an airborne manner.
www.medicinenet.com /measles_rubeola/glossary.htm   (5759 words)

  
 The Turkish Journal of Pediatrics   (Site not responding. Last check: 2007-09-17)
Childhood acute idiopathic thrombocytopenic purpura (ITP) is generally a self-limited disorder with an excellent prognosis1,2.
High-dose intravenous gammaglobulin for idiopathic thrombocytopenic purpura in childhood.
Intravenous immunoglobulin for idiopathic thrombocytopenic purpura (ITP) in childhood.
tjp.dergisi.org /text.php3?id=93   (2888 words)

  
 Vaccins and SBS - Bimbi scossi - English
Acute TP seems a rare complication of measles-rubella and MMR vaccination but clinicians had to be informed of the possibility of their occurrence.
A case of acute thrombocytopenic purpura, presented with sudden onset of petechiae and ecchymoses, as a possible complication of antinfluenza vaccination with inactivated viruses is reported.
As evaluated by the clinical course and the presence of AAb, post-vaccination thrombocytopenic purpura appears to be indistinguishable from childhood acute idiopathic thrombocytopenic purpura.
www.mednat.org /vaccini/bimbi_scossi.htm   (2788 words)

  
 Hemolytic-Uremic Syndrome (HUS) & Thrombotic Thrombocytopenic Purpura (TTP) - nephrologychannel
Hemolytic-Uremic Syndrome (HUS) & Thrombotic Thrombocytopenic Purpura (TTP) - nephrologychannel
Hemolytic-uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are microangiopathic disorders � that is, they are characterized by abnormalities (chiefly blood clots) that occur within the small blood vessels of the body.
Purpura (bleeding into the tissues) sometimes can be seen in the skin, and patients often complain of tiredness due to anemia.
www.nephrologychannel.com /hus_ttp   (624 words)

  
 Idiopathic Thrombocytopenia Purpura - My Child Has - Children's Hospital Boston
Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder that causes the body to destroy its platelets, the blood cells necessary to control bleeding.
Purpura refers to the purple discoloring of the skin, as with a bruise.
Chronic thrombocytopenic purpura - the onset of the disorder can happen at any age, and the symptoms last a minimum of six months and can persist for many years.
www.childrenshospital.org /az/Site1138/mainpageS1138P0.html   (1389 words)

  
 Idiopathic Thrombocytopenic Purpura
Acute ITP usually has a very sudden onset and the symptoms usually disappear in less than six months (often within a few weeks).
Acute ITP is the most common form of the disorder.
purpura - the purple color of the skin after blood has "leaked" under it.
www.healthsystem.virginia.edu /uvahealth/adult_blood/itp.cfm   (707 words)

  
 Thrombocytopenic purpura nd Traditional Chinese Medicine In China   (Site not responding. Last check: 2007-09-17)
Acute type of thrombocytopenic purpura is commonly found in adolescents.
Physical examination of acute type reveals no particular signs but infection and hemorrhage, while in chronic type which is recurrent in attack, spelenomegaly may be the only finding.
As for cases with persistent purpuras and splenomegaly, add 3 grams of notoginseng powder (taken after being mixed with the finished decoction), 6 grams of prepared aconite root are added for chronic cases marked with aversion to cold, cold limbs, aching pain of the loins and loose stool.
www.tcmtreatment.com /images/diseases/thrombocytopenic-purpura.htm   (518 words)

  
 Basic Summary for Immune Thrombocytopenic Purpura - WrongDiagnosis.com
Idiopathic thrombocytopenic purpura, Thrombocytopenic purpura, autoimmune, Autoimmune thrombocytopenic purpura
Immune Thrombocytopenic Purpura is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH).
This means that Immune Thrombocytopenic Purpura, or a subtype of Immune Thrombocytopenic Purpura, affects less than 200,000 people in the US population.
www.wrongdiagnosis.com /i/immune_thrombocytopenic_purpura/basics.htm   (442 words)

  
 Acute Idiopathic Thrombocytopenic Purpura --- Management in Childhood -- Buchanan et al. 89 (4): 1464 -- Blood
Thus, the overall risk-benefit ratio of IVIg or glucocorticoids in the "typical" child with acute ITP who does not exhibit prominent mucosal hemorrhage is not addressed by the panel.
The result of the "opinions" of a very small number of "experts" (only 6 of the total 13 for questions relating to children) has therefore been to arrive at consensus guidelines that are in many respects in contradiction to those already published in the UK, based on much of the same evidence.
Lilleyman JS: Intracranial haemorrhage in idiopathic thrombocytopenic purpura.
www.bloodjournal.org /cgi/content/full/89/4/1464   (2209 words)

  
 Current topic: Idiopathic thrombocytopenic purpura -- Bolton-Maggs 83 (3): 220 -- Archives of Disease in Childhood
Intravenous immunoglobulin versus oral corticosteroids in acute immune thrombocytopenic purpura in childhood.
Treatment of childhood acute immune thrombocytopenic purpura with anti-D immune globulin or pooled immune globulin.
In-labelled platelets and the efficiency of splenectomy in children and adults with idiopathic thrombocytopenic purpura: a study of 578 patients with 268 splenectomies.
adc.bmjjournals.com /cgi/content/full/83/3/220   (2075 words)

  
 Idiopathic Thrombocytopenic Purpura   (Site not responding. Last check: 2007-09-17)
ITP or idiopathic thrombocytopenic purpura is defined as isolated thrombocytopenia (decreased platelet count) with normal bone marrow in the absence of other causes for thrombocytopenia.
There are 2 distinct clinical syndromes manifest as an acute condition in children and a chronic condition in adults.
The pathogenetic role and the clinical importance of the presence of antiphospholipid antibodies (APAs) in patients with immune thrombocytopenic purpura (ITP) are not clear.
www.thedoctorsdoctor.com /diseases/itp.htm   (1133 words)

  
 Thrombotic Thrombocytopenic Purpura Associated with Bone Marrow Metastasis and Secondary Myelofibrosis in Cancer -- ...   (Site not responding. Last check: 2007-09-17)
Thrombotic thrombocytopenic purpura subsequent to acute myelogenous leukemia chemotherapy.
von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome.
Tsai H-M, Lian EC-Y. Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura.
theoncologist.alphamedpress.org /cgi/content/full/8/4/375   (2747 words)

  
 ITP journal article list
Komrower GM, Watson GH: Prognosis in idiopathic thrombocytopenic purpura of childhood.
Lusher JM, Zuelzer WW: Idiopathic thrombocytopenic purpura in childhood.
Whipple AO: Splenectomy as a therapeutic measure in thrombocytopenic purpura haemorrhagica.
www.itppeople.com /artlist.htm   (5567 words)

  
 Purpura, Idiopathic Thrombocytopenic
Idiopathic thrombocytopenic purpura (ITP) is a rare autoimmune bleeding disorder characterized by the abnormal decrease of certain red blood cells called platelets, a condition known as thrombocytopenia.
Henoch-Schonlein purpura is a rare inflammatory disease of the small blood vessels (capillaries) and is usually a self-limited disease.
The exact cause of Schonlein-Henoch purpura is not fully understood, although research suggests that it may be an autoimmune disease or, in some rare cases, an extreme allergic reaction to certain offending substances (e.g., foods or drugs).
hw.healthdialog.com /kbase/nord/nord258.htm   (2191 words)

  
 IngentaConnect Acute thrombotic thrombocytopenic purpura following doxycycline t...   (Site not responding. Last check: 2007-09-17)
IngentaConnect Acute thrombotic thrombocytopenic purpura following doxycycline t...
Acute thrombotic thrombocytopenic purpura following doxycycline treatment of Chlamydia pneumoniae infection in a patient with dermatomyositis
A 48-year-old white female who was suffering from dermatomyositis and Chlamydia pneumoniae infection, developed acute rapidly fatal thrombotic thrombocytopenic purpura (TTP) following treatment with steroids and doxycycline.
www.ingentaconnect.com /content/bsc/clh/2004/00000026/00000002/art00011   (199 words)

  
 Acute thrombocytopenic purpura definition - Medical Dictionary definitions of popular medical terms
Acute thrombocytopenic purpura: The sudden onset of low blood platelet levels with bleeding into the skin and elsewhere.
Acute thrombocytopenic purpura (ATP) can be due to many causes.
It may, for example, constitute a potentially serious complication during the acute phase of measles.
www.medterms.com /script/main/art.asp?articlekey=6578   (95 words)

  
 Purpura, Idiopathic Thrombocytopenic
Idiopathic thrombocytopenic purpura (ITP) is a rare autoimmune bleeding disorder characterized by the abnormally low levels of certain blood cells called platelets, creating a condition known as thrombocytopenia.
Acute ITP accounts for about 90% of cases, and chronic ITP accounts for the remainder.
Onset of acute ITP is often rapid, while the onset of the chronic form may be gradual.
www.webmd.com /hw/anemia/nord258.asp   (567 words)

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