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Topic: Adenomyosis

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	Adenomyosis
		Adenomyosis may be mild and cause no symptoms at all, or, in more severe forms, it may lead to heavy bleeding and severe cramping during menstrual periods.
		In situations where the adenomyosis is confined to isolated areas in the muscle wall, an attempt may be made to surgically remove these areas and repair the rest of the uterus.
		Adenomyosis is defined as the presence of uterine lining cells within an otherwise normal uterine muscle wall.
	www.fibroidsecondopinion.com /adenomyosis.htm (500 words)

	Adenomyosis - Wikipedia, the free encyclopedia
		Adenomyosis is a medical condition characterized by the presence of ectopic endometrial tissue (the inner lining of the uterus) within the myometrium (the thick, muscular layer of the uterus).
		Some say that the reason adenomyosis is common in women between the ages of 35 and 50 is because it is between these ages that women have an excess of estrogen.
		In particular, MR is better able to differentiate adenomyosis from multiple small uterine fibroids the uterus will have a thickened junctional zone with diminished signal on both T1 and T2 weighted sequences due to succeptibility effects of iron deposition due to chronic microhemorrhage.
	en.wikipedia.org /wiki/Adenomyosis (507 words)

	Adenomyosis - An Internal Uterine Endometriosis - G01
		Adenomyosis is defined as the presence of endometrial glands and supporting tissues in the muscle of the uterus where it normally would not occur.
		The glandular change of the endometrial cells in adenomyosis are often incomplete in the second half of the menstrual cycle (luteal phase) and as a result, adenomyosis may not be very responsive to suppression by progesterone.
		Conservative surgery for adenomyosis is about 50% effective (24), so it is still likely that hysterectomy is more successful in treating it even though we do not know for sure what the success rate of hysterectomy is. It is probably that hysterectomy is at least 80% or more effective.
	www.wdxcyber.com /npain09.htm (1231 words)

	Disease Profile for Adenomyosis - G01
		Adenomyosis is the presence of endometrial glands and supporting tissues in the muscle of the uterus where it would not occur normally.
		Patterns of adenomyosis as recognized by MRI seem to either be diffusely spread throughout the uterus (about 66%) or focal lesions (33%) that only occur in one or two places (3).
		Focal adenomyosis appears on both T2-weighted and contrast-enhanced T1-weighted MR images as a localized, low-signal-intensity round or oval mass with a diameter of 2-7 cm (mean, 3.8 cm) and usually has ill-defined margins.
	www.wdxcyber.com /dxppn011.htm (914 words)

	eMedicine - Uterus, Adenomyosis : Article by Karen L Reuter
		Adenomyosis, although considered a variant of endometriosis, is different because of its behavior.
		The gross ultrasonographic description of adenomyosis includes irregular, myometrial, cystic spaces predominantly involving the posterior uterine wall, an enlarged uterus with a widened posterior wall (see Image 1), an eccentric endometrial cavity, and decreased uterine echogenicity without lobulations, contour abnormality, or mass effects (which is more commonly seen with leiomyomas).
		From a series of 29 women with evidence of adenomyosis at hysterectomy, the morphologic criterion for adenomyosis at endovaginal ultrasonography was the presence of myometrial heterogeneous and hypoechoic areas with or without cysts.
	www.emedicine.com /radio/topic737.htm (2118 words)

	Nikon MicroscopyU: Human Pathology Digital Image Gallery - Adenomyosis
		Adenomyosis is a benign uterine condition that involves the invasion of tissue and glands typically confined to the inner mucous membrane of the uterus (termed the endometrium) into the adjacent muscle layer of the uterine wall, the myometrium.
		The actual incidence of adenomyosis is unknown due to the fact that the condition is often asymptomatic and is very difficult to diagnose, estimates ranging widely from 20 to 65 percent of the female population.
		Adenomyosis at 10x Magnification - Approximately 80 percent of the time adenomyosis occurs in women that also have another pathologic condition of the uterus, such as endometriosis or the growth of fibroids or polyps.
	www.microscopyu.com /galleries/pathology/adenomyosis.html (334 words)

	Center for Uterine Fibroids: Adenomyosis (Site not responding. Last check: 2007-10-30)
		Adenomyosis is a benign disease of the uterus in which components normally limited to the endometrium (the thin innermost uterine layer) are found within the myometrium (the middle muscular layer of the uterus).
		Adenomyosis most commonly affects women between the ages of 40 and 50 years and is associated with a past history of childbirth.
		More than 80% of women with adenomyosis have another pathologic process in the uterus; 50% of patients have associated fibroids (benign smooth muscle tumors of the uterus), approximately 11% have endometriosis (endometrial tissue outside of the uterus, most commonly in the ovaries), and 7% have endometrial polyps (benign outgrowths of endometrial tissue).
	www.fibroids.net /html/adenomyosis.htm (597 words)

	Understanding the Basics of Adenomyosis (Site not responding. Last check: 2007-10-30)
		This theory is supported by the fact that during microscopic examination of adenomyosis in the lab, it is possible in some cases to follow the endometrium in a continuous non-broken layer from its normal location on the lining and observe it invading the muscle.
		Adenomyosis is not thought to reduce fertility, although the real effect on fertility is virtually impossible to know since it is so difficult to diagnose the disease in women who have a uterus.
		Adenomyosis used to be called "endometriosis interna," since it can look somewhat like endometriosis under the microscope but occurs within the muscle wall of the uterus, not on pelvic surfaces as does endometriosis.
	www.endometriosistreatment.org /html/adenomyosis.html (2536 words)

	Encyclopedia article: Adenomyosis (Site not responding. Last check: 2007-10-30)
		The condition is typically found in women in the ages between 35 and 50.
		Patients with adenomyosis can have painful and/or profuse menses (The monthly discharge of blood from the uterus of nonpregnant women from puberty to menopause) (dysmenorrhea & hypermenorrhea, respectively).
		Patients with adenomyosis often also have leiomyoma (Benign tumor of smooth muscle (usually in the uterus or digestive tract)) ta and/or endometriosis (The presence of endometrium elsewhere than in the lining of the uterus; causes premenstrual pain and dysmenorrhea).
	www.absoluteastronomy.com /encyclopedia/a/ad/adenomyosis.htm (372 words)

	Adenomyosis
		Adenomyosis is a fairly frequent disorder in adult women characterized by the haphazard location of endometrial glands and stroma deep within the myometrium of the uterus.
		Uterine adenomyosis was found in all (14 of 14) mice dosed with tamoxifen and most mice (12 of 14) treated with toremifene, but in none of the vehicle-dosed controls, in only one animal treated with raloxifene at 42 and 90 days after dosing and in none of the mice treated with estradiol at 42 days.
		Transvaginal ultrasound in the diagnosis of diffuse adenomyosis.
	www.thedoctorsdoctor.com /diseases/adenomyosis.htm (4928 words)

	EAGO Newsletter
		Adenomyosis is a disease occurring at the interface between the endometrium and the myometrium.
		The frequency of diagnosis of adenomyosis ranged from 12% to 58% among the hospitals, and 10% to 88% among the 25 pathologists.
		Adenomyosis is characterised by disruption of the normal myometrial zonal anatomy which is best demonstrated on T2-weighted images where the contrast between the low signal inner myometrium (junctional zone) and the intermediate signal outer myometrium is maximal.
	www.obgyn.net /eago/art04.htm (2362 words)

	Adenomyosis - New Treatments, May 2, 2008
		Adenomyosis is characterized by the presence of endometrial glands and stroma in the myometrium and is often associated with local myometrial hypertrophy.
		The pathologic diagnosis of adenomyosis is highly dependent on the number of sections from the uterine specimen that are processed for analysis.
		The clinical diagnosis of adenomyosis usually is based on the triad of menorrhagia, dysmenorrhea, and a slightly enlarged, "boggy" uterus on physical examination.
	www.ccspublishing.com /journals4a/adenomyosis.htm (442 words)

	Adenomyosis: symptoms, cause, treatment, prevention, complications, long-term outlook
		Adenomyosis is also called: endometriosis interna, uterine endometriosis, endometriosis of the uterus, and internal endometriosis.
		Adenomyosis is a disease that is closely related to endometriosis.
		Adenomyosis occurs when the old tissue and blood cannot escape the uterine muscle and flow out of the cervix as part of normal menses.
	www.mamashealth.com /women/adenomyosis.asp (240 words)

	Uterine Fibroid Embolization - Physician's Resource - Patient's Guide
		Adenomyosis most commonly occurs in women who have had children, raising questions as to a possible role that pregnancy may have in its development (2).
		Adenomyosis and particularly adenomyomas are commonly misdiagnosed as fibroids, because the symptoms are similar.
		Adenomyosis is a difficult condition to both diagnose and manage, with hysterectomy the most commonly used definitive therapy.
	www.fibroidoptions.com /adeno.htm (1357 words)

	Adenomyosis Treatment
		Adenomyosis may be found spread throughout the uterine wall, or it may form small nodules.
		Adenomyosis may interfere with fertility either directly, by compressing the uterine lining, or indirectly, by compressing blood vessels in the uterine wall that supply blood to the uterine lining and nourish an early pregnancy.
		In a woman who still has her uterus, adenomyosis is typically discovered during an ultrasound procedure to diagnose the cause of infertility or to monitor ovulation induction treatment.
	health.ivillage.com /gyno/uterus/0,,6gqj,00.html (569 words)

	Medcyclopaedia - Adenomyosis, uterine
		Adenomyosis typically affects multiparous women between the ages of 35 and 50, who present with painful irregular periods or excessive menstrual bleeding.
		Adenomyosis is usually generalized, with diffuse involvement of the uterus.
		At MRI, in diffuse adenomyosis, the uterine body and fundus are diffusely enlarged, the low signal intensity junction zone is increased in thickness and segmentally or diffusely extends peripherally through the myometrium (Fig.4).
	www.medcyclopaedia.com /library/topics/volume_iv_2/a/ADENOMYOSIS_UTERINE.aspx (709 words)

	adenomyosis
		Adenomyosis (AD-en-oh-my-oh-sis) is a benign (non-cancerous) condition of the uterus.
		Adenomyosis is similar to Endometriosis, both are conditions in which the lining of the uterus grows where it shouldn't and both are progressive (will continue to grow).
		Because Adenomyosis grows inside the uterine walls, it is not readily visible with a laparascope (looks inside the abdominal cavity) or a hysteroscope (which looks inside the uterus).
	www.geocities.com /kristiswatkins/adenomyosis.html (568 words)

	MedlinePlus Medical Encyclopedia: Adenomyosis
		Adenomyosis is uterine thickening that occurs when endometrial tissue, which normally lines the uterus, extends into the fibrous and muscular tissue of the uterus.
		Sometimes a focal area of adenomyosis appears to cause a mass or growth within the uterus, which is called an adenomyoma.
		Additionally, an ultrasound examination of the uterus may be helpful in differentiating between adenomyosis and other uterine tumors.
	www.nlm.nih.gov /medlineplus/ency/article/001513.htm (394 words)

	Endometriosis and Adenomyosis
		There is a condition which is similar to endometriosis known as adenomyosis, in which the endometrial tissue (the uterine lining, glands, and connective tissue) invades the deeper muscle layers of the uterus.
		Unlike endometriosis, some researchers believe that adenomyosis may set in after pregnancy and delivery; women in their forties and fifties who have given birth to at least one child are more likely to develop adenomyosis.
		It may be possible to detect adenomyosis with a magnetic resonance imaging (MRI) scan or a hysteroscopy (a telescope, similar to the laparoscope, placed through the cervix).
	www.endo-resolved.com /adenomyosis.html (330 words)

	Adenomyosis Sufferer
		The exact prevalence of adenomyosis is not known because the diagnosis can be made only by microscopic examination of uterine specimens obtained during surgery or, less often, during biopsy.
		Adenomyosis can also be extremely painful, causing heavy uterine cramps (not always just during the period).
		Unlike a healthy uterus, a uterus with Adenomyosis may feel boggy, or squishy (during a pelvic exam) and tends to be enlarged, but again, not for every woman.
	www.eccentrix.com /members/jeb1493/disease/ad (448 words)

	Diagnose-Me: Condition: Adenomyosis
		Adenomyosis, also known as internal endometriosis, is a benign disease of the uterus in which endometrial tissue, which normally lines the uterus, extends outward into the fibrous and muscular tissue of the uterus (the myometrium).
		One popular theory suggests that the barrier between the endometrium and the myometrium, which normally prevents invasion of endometrial glands into the myometrium, is compromised, allowing invasion to occur.
		While some studies estimate that 20% of women have adenomyosis, the exact rate of incidence of adenomyosis is unknown because a diagnosis can be made only after a pathologist examines uterine wall samples obtained during surgery or biopsy.
	www.diagnose-me.com /cond/C537734.html (1310 words)

	Pelvic Pain \| Ask Dr. Cook \| Q & A
		Adenomyosis is usually a result of the endometrium invading into the muscle wall of the uterus.
		The adenomyosis is usually not a discrete lesion, but often sends out a diffuse network of branching endometrial glands extending from the endometrium throughout the muscle wall of the uterus.
		In contrast the adenomyosis is so diffuse that an adenomyomectomy (removal of the adenomyosis with reconstruction of the uterus) will reduced the amount of adenomyosis present but by the nature of the lesion a significant amount usually remains in the uterus.
	www.pelvicpain.com /askdoctor_QA.html (11992 words)

	Alternatives to Hysterectomy
		Adenomyosis may present as a diffuse condition or it may be focal.
		Further studies are needed to determine the correlation between uterine size, extent of adenomyosis and the occurrence of infertility and obstetric complications.
		Adenomyosis is a relatively common condition, which must be considered in the evaluation of any woman with abnormal uterine bleeding.
	althysterectomy.org /adenomyosis.htm (1258 words)

	Adenomyosis
		For adenomyosis is a condition in which the glandular layer of the endometrium invades the muscular middle layer of myometrium.
		Adenomyosis, on the other hand, is normal glandular tissue which grows into the muscle probably because of a breakdown in the anatomic separation between the muscle and the endometrium.
		Adenomyosis is a misery women have exclusive of men, thanks to having a uterus.
	www.gynob.com /adeno.htm (1017 words)

	Diffuse and Focal Adenomyosis: MR Imaging Findings -- Byun et al. 19 (Supplement 1): 161 -- RadioGraphics (Site not responding. Last check: 2007-10-30)
		Adenomyosis is associated with myometrial hypertrophy (1) and
		Adenomyosis and leiomyoma: differential diagnosis with MR imaging.
		Adenomyosis: specificity of 5 mm as the maximum normal uterine junctional zone thickness in MR images.
	radiographics.rsnajnls.org /cgi/content/full/19/suppl_1/S161 (3334 words)

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