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Topic: Adenylate kinase

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	[No title]
		(NM_001625) adenylate kinase 2 isoform a; Adenylate kinase-2, mitochondrial [Homo sapiens] gi11423967refXP_001762.1
		>gi729866spP39068KAD_BORPE ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) gi628628pirS43016 adenylate kinase (EC 2.7.4.3) - Bordetella pertussis gi453621embCAA82801.1
		>gi97155pirS15290 adenylate kinase (EC 2.7.4.3) - Haemophilus influenzae gi43591embCAA40570.1
	www.science.gmu.edu /~greck/Blast_1ak2-nr.html (624 words)

	ADENYLATE KINASE FAMILY
		NM_001625 adenylate kinase 2 isoform a Adenylate kinase2 mitochondrial [Homo sapiens]gi11423967refXP_001762.1
		NM_013410 adenylate kinase 3 Adenylate kinase3 mitochondrial GTPAMP phosphotransferase [Homo sapiens]gi125157spP27144KAD4_HUMAN Adenylate kinase isoenzyme 4 mitochondrial ATPAMP transphosphorylasegi1070480pirKIHUA3 nucleosidetriphosphateadenylate kinase EC 2.7.4.10 3 humangi28577embCAA43088.1
		AJ248286 adenylate kinase adk EC 2.7.4.3 [Pyrococcus abyssi]
	eyesite.cryst.bbk.ac.uk /family60 (3020 words)

	Kinase - Wikipedia, the free encyclopedia
		In biochemistry, a kinase is a type of enzyme that transfers phosphate groups from high-energy donor molecules, such as ATP, to specific target molecules (substrates); the process is termed phosphorylation.
		In some settings, the purpose of phosphorylation is to "activate" or "energize" a molecule, increasing its energy so it is able to participate in a subsequent reaction with a negative free-energy change.
		The largest group of kinases are Protein kinases, which act on and modify the activity of specific proteins.
	en.wikipedia.org /wiki/Kinase (349 words)

	Plant Gene Register PGR98-166 (Site not responding. Last check: 2007-10-30)
		Adenylate kinase then converts AMP into ADP, which is the substrate for the light phase of photosynthesis.
		Adenylate kinases have been identified from a wide variety of sources including 27 species of archaebacteria and eubacteria, 3 species of single cell eukaryotes, 2 species of yeast, 3 species of plants, 3 species of mammals, and birds.
		The upstream receptor protein kinase gene is expressed from the same strand and is extremely close to the adenylate kinase gene.
	www.tarweed.com /pgr/PGR98-166.html (2099 words)

	AK1 (Site not responding. Last check: 2007-10-30)
		Adenylate kinase 1 is essential for the maintenance of cellular energetic economy and is a key enzyme in the synthesis, equilibration and regulation of adenine nucleotides.
		Isoforms of adenylate kinase are found in mitochondria, cytosol, and cellular membranes, creating an integrated phosphotransfer network.
		Adenylate kinase deficiency in the erythrocyte is a rare genetic disorder associated with hemolytic anemia.
	www.sgc.ox.ac.uk /structures/AK1_1z83.html (392 words)

	Adenylate kinase AK1 knockout heart: energetics and functional performance under ischemia-reperfusion -- Pucar et al. ...
		Adenylate kinase phosphotransfer flux was determined from the
		Adenylate kinase: kinetic behavior in intact cells indicates it is integral to multiple cellular processes.
		Adenylate kinase activity in ejaculated bovine sperm flagella.
	ajpheart.physiology.org /cgi/content/full/283/2/H776 (4256 words)

	[No title]
		This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II.
		The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits.
		Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules.
	www.mpi-cbg.de /downloads/Results.xls (1478 words)

	Rapid microbial testing with adenylate kinase technology
		Adenylate kinase, an enzyme, is another element vital to all living organisms for the maintenance of energy pathways and metabolism.
		AK technology utilises adenosine diphosphate (ADP) and microbial adenylate kinase to catalyse the production of ATP.4 Given the ability of enzymes to effect reactions without being depleted or changed in any way, it is possible to use microbial AK to generate almost unlimited amounts of its products.
		3 Adenylate kinase technology is exclusively licensed to Celsis International Plc by the UK Department of Defense and Scientific Testing Laboratories (Dstl) for use in the personal care, pharmaceutical and beverage industries.
	www.personalcaremagazine.com /story.asp?id=489 (2011 words)

	Protein Folding and Function: The N-Terminal Fragment in Adenylate Kinase -- Kumar et al. 80 (5): 2439 -- Biophysical ...
		The P-loop is characteristic of adenylate kinases and
		Structure of the complex between adenylate kinase from Escherichia coli and the inhibitor Ap A refined at 1.9 Å resolution.
		Mutations in the nucleotide binding loop of adenylate kinase of Escherichia coli.
	www.biophysj.org /cgi/content/full/80/5/2439 (7250 words)

	Reversal of the ATP-liganded State of ATP-sensitive K+ Channels by Adenylate Kinase Activity -- Elvir-Mairena et al. ...
		attributable to an extramitochondrial isoform of adenylate kinase.
		Adenylate kinase activity was measured by enzyme-coupled spectrophotometry at 22-25 °C (26).
		Adenylate Kinase as a Virulence Factor of Pseudomonas aeruginosa
	www.jbc.org /cgi/content/full/271/50/31903 (4320 words)

	Protein Targeting of an Unusual, Evolutionarily Conserved Adenylate Kinase to a Eukaryotic Flagellum -- Pullen et al. ...
		Adenylate kinase activity is associated with purified flagella (A) and cytoskeletons (the subpellicular microtubule and flagellar fraction (B).
		Cloning and characterization of adenylate kinase from Chlamydia pneumoniae.
		Sanchez, L.B., and Muller, M. Cloning and heterologous expression of Entamoeba histolytica adenylate kinase and uridylate/cytidylate kinase.
	www.molbiolcell.org /cgi/content/full/15/7/3257 (5467 words)

	Genetically Engineered Zinc-chelating Adenylate Kinase from Escherichia coli with Enhanced Thermal Stability -- Perrier ...
		In contrast with adenylate kinase from Gram-negative bacteria, the enzyme from Gram-positive organisms harbors a structural
		in Escherichia coli adenylate kinase with cysteine residues.
		The abbreviations used are: AK, adenylate kinase; AK, muscle cytosolic adenylate kinase; AK
	www.jbc.org /cgi/content/full/273/30/19097 (3168 words)

	References - adenylate kinase - HORT640 - Metabolic Plant Physiology - Department of Horticulture and Landscape ...
		Carrari F, Coll-Garcia D, Schauer N, Lytovchenko A, Palacios-Rojas N, Balbo I, Rosso M, Fernie AR 2005 Deficiency of a plastidial adenylate kinase in Arabidopsis results in elevated photosynthetic amino acid biosynthesis and enhanced growth.
		Gutierrez JA, Csonka LN 1995 Isolation and characterization of adenylate kinase (adk) mutations in Salmonella typhimurium which block the ability of glycine betaine to function as an osmoprotectant.
		Hatch MD 1982 Properties and regulation of adenylate kinase from Zea mays leaf operating in C4 pathway photosynthesis.
	www.hort.purdue.edu /rhodcv/hort640c/referen/adenyk.htm (610 words)

	GeneCard for AK1
		Marra M.A. wt p53 dependent expression of a membrane-associatedisoform of adenylate kinase.
		Collavin L....Schneider C. Cloning and expression of human adenylate kinase 2 isozymes: differential expression of adenylate kinase 1 and 2 in human muscle tissues.
		Wang G....Liu Y.F. Red cell adenylate kinase deficiency: molecular study of 3 new mutations (118G>A,190G>A, and GAC deletion) associated with hereditary nonspherocytic hemolytic anemia.
	www.genecards.org /cgi-bin/carddisp.pl?gene=AK1 (765 words)

	Energetic communication between mitochondria and nucleus directed by catalyzed phosphotransfer -- Dzeja et al. 99 (15): ...
		Creatine kinase and adenylate kinase are critical components of the intracellular phosphoryl transfer network responsible
		Suppressed nuclear import under adenylate kinase deficit, rescued by activation of creatine kinase phosphotransfer.
		Impaired nuclear import of H1 in neonatal cells with inhibited adenylate kinase was rescued by induction of the alternate
	www.pnas.org /cgi/content/full/99/15/10156 (4701 words)

	Adenylate Kinase (AK) for rapid microbial detection
		During incubation the sample itself is diluted in growth medium so that any effects on the final assay are minimized, and any microbes present in the original sample are allowed to multiply and generate adenylate kinase and ATP.
		At the end of the treatment, mold adenylate kinase will be dispersed throughout the broth and a sub-sample can be assayed in a cuvette as normal.
		Similar to broth selection for ATP Bioluminescence assays, the broth used to incubate the sample must be capable of supporting growth of viable organisms, be able to neutralize any preservative systems, contain relatively low levels of ATP and have good batch to batch consistency.
	www.celsis.com /rapid_tech_aktech.htm (1452 words)

	Adenylate kinase phosphotransfer communicates cellular energetic signals to ATP-sensitive potassium channels -- ...
		Adenylate kinase phosphotransfer communicates cellular energetic signals to ATP-sensitive potassium channels -- Carrasco et al.
		The Glycolytic Enzymes, Glyceraldehyde-3-phosphate Dehydrogenase, Triose-phosphate Isomerase, and Pyruvate Kinase Are Components of the KATP Channel Macromolecular Complex and Regulate Its Function
		Cellular Characterization of Adenylate Kinase and Its Isoform: Two-Photon Excitation Fluorescence Imaging and Fluorescence Correlation Spectroscopy
	www.pnas.org /cgi/content/abstract/98/13/7623 (1427 words)

	Energy Citations Database (ECD) - Energy and Energy-Related Bibliographic Citations
		Energy Citations Database (ECD) Document #5623422 - Adenylate kinase increases adenylate cyclase activity in membranes from rat lung
		Availability information may be found in the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or via the "Full-text Availability" link.
		Adenylate kinase increases adenylate cyclase activity in membranes from rat lung
	www.osti.gov /energycitations/product.biblio.jsp?osti_id=5623422 (127 words)

	Adenylate Kinase - the movie (Site not responding. Last check: 2007-10-30)
		"Movie of the structural changes during a catalytic cycle of nucleoside monophosphate kinases".
		There is videotape (PAL or NTSC) available for academic institutions.
		Lesk and C. Chothia, which describes the motion in adenylate kinases as 'predominantly hinge'.
	bio5.chemie.uni-freiburg.de /ak-movie (57 words)

	Human protein: Q96MA6 - CDNA FLJ32704 fis, clone TESTI2000591, weakly similar to ADENYLATE KINASE, CHLOROPLAST (EC ) ...
		Human protein: Q96MA6 - CDNA FLJ32704 fis, clone TESTI2000591, weakly similar to ADENYLATE KINASE, CHLOROPLAST (EC) (OTTHUMP00000022737) (Chromosome 9 open reading frame 98).
		You can add a comment for this protein inside the Harvester Wiki.
		CDNA FLJ32704 fis, clone TESTI2000591, weakly similar to ADENYLATE KINASE, CHLOROPLAST (EC 2.7.4.3) (OTTHUMP00000022737) (Chromosome 9 open reading frame 98).
	harvester.embl.de /harvester/Q96M/Q96MA6.htm (655 words)

	UniProtKB/Swiss-Prot entry O59443 [KADA_PYRHO] Adenylate kinase
		They link to the user manual or other documents.
		: Belongs to the archaeal adenylate kinase family.
		View cluster of proteins with at least 50% / 90% / 100% identity.
	www.expasy.org /uniprot/O59443 (195 words)

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