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Topic: Adhesion (medicine)

    Note: these results are not from the primary (high quality) database.

Roles of the Intercellular Adhesion Molecule Nectin in Intracellular Signaling -- Shimizu and Takai 134 (5): 631 -- Journal of Biochemistry Roles of the Intercellular Adhesion Molecule Nectin in Intracellular Signaling -- Shimizu and Takai 134 (5): 631 -- Journal of Biochemistry Roles of the Intercellular Adhesion Molecule Nectin in Intracellular Signaling Requirement of the actin cytoskeleton for the association of nectins with other cell adhesion molecules at adherens and tight junctions in MDCK cells jb.oupjournals.org /cgi/content/abstract/134/5/631

Hospital Practice: Integrins: The Molecular Glue of Life The ligands are mainly ICAMs (intercellular adhesion molecules) 1 and 2, of the immunoglobulin superfamily. A relation between these glycoproteins and an inherited defect of neutrophil adhesion was suggested by the observation that monoclonal antibodies against either the alpha or beta chains of the newly discovered heterodimers could induce in vitro defects in chemotaxis and phagocytosis similar to those observed in patients. Among the adhesion molecules, integrins are the most important group known to participate in all types of adhesion. www.hosppract.com /issues/2000/03/etzioni.htm

Soluble Intercellular Adhesion Molecule-1 (sICAM-1) and Interferon-Gamma in Bronchoalveolar Lavage Fluid from Children with Airway Diseases -- MARGUET et al. 162 (3): 1016 -- American Journal of Respiratory and Critical Care Medicine Intercellular adhesion molecule-1 (ICAM-1) in the pathogenesis of asthma. The expression of intercellular adhesion molecule-1 and the 1-integrins in asthma. Intercellular adhesion molecule-1 (ICAM-1) and endothelial leucocyte adhesion molecule-1 (ELAM-1) expression in the bronchial mucosa of normal and asthmatic subjects. www.ajrccm.org /cgi/content/full/162/3/1016

Biologically Active Intercellular Adhesion Molecule-1 Is Shed as Dimers by a Regulated Mechanism in the Inflamed Pleural Space -- Melis et al. 167 (8): 1131 -- American Journal of Respiratory and Critical Care Medicine Intercellular adhesion molecule-1 (ICAM-1) is an adhesion molecule Intercellular adhesion molecule-1 dimerization and its consequences for adhesion mediated by lymphocytes function associated-1. The native structure of intecellular adhesion molecule-1 (ICAM-1) is a dimer: correlation with binding to LFA-1. ajrccm.atsjournals.org /cgi/content/full/167/8/1131

eMedicine - Complement Receptor Deficiency : Article by Alan P Knutsen, MD The leukocyte adhesion deficiency syndromes are due to defects of several molecules of the adhesion cascade. Ligands for CD11a/CD18 are intercellular adhesion molecules (ICAMs), for CD11b/CD18 complement C3bi and ICAM-1 and for CD11c/CD18 C3bi and ICAM-1. Leukocyte adhesion deficiency type 1 (LAD1) is due to a deficiency of CD18. www.emedicine.com /ped/topic448.htm   (3001 words)

Reference.com/Web Directory/Top/Science/Biology/Immunology Inflammation: The Leukocyte Adhesion Cascade - A detailed look at its various stages. Immune-Monitoring.de - A discussion-based site which features new methods in immune monitoring and topics on intensive care medicine relating to immunology and immune monitoring. Lymphocyte Traffic and Homing - Illustrated description of how leukocytes recirculate and emigrate into lymphatic tissue during the immune responses. www.reference.com /Dir/Science/Biology/Immunology   (77 words)

The Leukocyte Function-Associated Antigen-1 (LFA-1)-Binding Site on ICAM-3 Comprises Residues on Both Faces of the First Immunoglobulin Domain -- Bell et al. 161 (3): 1363 -- The Journal of Immunology ICRF Cell Adhesion Laboratory, Imperial Cancer Research Fund Laboratories, University of Oxford, Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford, OX3 9DS, U.K., and Lymphocyte function-associated antigen-1 binding residues in intercellular adhesion molecule-2 (ICAM-2) and the integrin binding surface in the ICAM subfamily Molecular Basis for Leukocyte Integrin {alpha}E{beta}7 Adhesion to Epithelial (E)-Cadherin www.jimmunol.org /cgi/content/abstract/161/3/1363   (77 words)

Cancer Cell Biology Researchers at the Institute for Molecular Medicine have found that multiple adhesive mechanisms are responsible for malignant cell adhesion to microvessel endothelial cells and to underlying subendothelial matrix, and they have begun to identify and isolate the receptors responsible. These studies are being extended into an examination of the role of integrins and nonintegrin adhesion components in the adhesion of metastatic cells to specific microvessel endothelial cells that have been established in culture and characterized. There are three major mechanisms whereby tumors escape immune recognition: (i) poor immunogenicity, when tumor cells lack expression of peptide:MHC ligands, adhesion molecules, and/or B7 (CD80/CD86) costimulatory molecules; (ii) antigenic modulation by antibodies; (iii) tumor-induced immune suppression by factors secreted by tumor cells (for example, TGFb). www.immed.org /illness/cancer_cell_biology_research.html   (77 words)

Chlamydia pneumoniae Seropositivity Is Associated With Increased Plasma Levels of Soluble Cellular Adhesion Molecules in Community-Dwelling Subjects: The Shimanami Health Promoting Program (J-SHIPP) Study -- Kohara et al. 33 (6): 1474 -- Stroke Yoshikuni Yamamoto, MD Michiya Igase, MD Tetsuro Miki, MD From the Department of Geriatric Medicine, Ehime University School of Medicine, Ehime University, Japan. Correspondence to Katsuhiko Kohara, MD, Department of Geriatric Medicine, Ehime University School of Medicine, Ehime University, Shigenobu-cho, Onsen-gun, Ehime 791-0295, Japan. Background and Purpose— In vitro studies have demonstrated stroke.ahajournals.org /cgi/content/abstract/33/6/1474   (331 words)

OBGYN.net - Editorial Advisor Stephen M. Cohen Cohen SM: Contemporary Technologies for the Treatment of Perimenapausal Bleeding: in Infertility and Reproductive Medicine Clinics of North America, WB Saunders, Orlando, Florida, Vol. Use of Interceed TC7 Absorbable Adhesion Barrier to Reduce the Extent and Severity of Adhesion Reformation in Women Undergoing Infertility Surgery: A Clinical Update; Malinak, K.R., Franklin, R.R., Cohen, S.M., et al. Prevention of Postsurgical Adhesions by Interceed (TC7), an Absorbable Adhesion Barrier: A Prospective, Randomized Multicenter Clinical Study; Cohen, S.M., Franklin, R.R., Haney, A.F., et al. www.obgyn.net /meet.asp?page=/all_advisors/S_Cohen   (2012 words)

University Week: First Russell Ross Lecture next Friday Hynes is a fellow of the Royal Society of London, a member of the Institute of Medicine, and a member of the National Academy of Sciences. Hynes’ work has focused on cell adhesion, or the ways cells attach themselves to body tissues, and has provided many important insights into the molecular basis of cell adhesion and its consequences. Some of the first knockout mice (mice bred with certain missing genes) lacking cell adhesion molecules were generated in his laboratory, and investigations with them have revealed much about the roles of cell adhesion molecules in development, inflammation, hemostasis, angiogenesis (blood vessel growth) and cancer. depts.washington.edu /~uweek/archives/2002.05.MAY_16/hs_c.html   (427 words)

Chlamydia pneumoniae Seropositivity Is Associated With Increased Plasma Levels of Soluble Cellular Adhesion Molecules in Community-Dwelling Subjects: The Shimanami Health Promoting Program (J-SHIPP) Study -- Kohara et al. 33 (6): 1474 -- Stroke Yoshikuni Yamamoto, MD Michiya Igase, MD Tetsuro Miki, MD From the Department of Geriatric Medicine, Ehime University School of Medicine, Ehime University, Japan. Correspondence to Katsuhiko Kohara, MD, Department of Geriatric Medicine, Ehime University School of Medicine, Ehime University, Shigenobu-cho, Onsen-gun, Ehime 791-0295, Japan. in 1999 in the Shimanami district, located in the southern part intl-stroke.ahajournals.org /cgi/content/full/33/6/1474   (3556 words)

SWAP-70 Regulates c-kit-Induced Mast Cell Activation, Cell-Cell Adhesion, and Migration -- Sivalenka and Jessberger 24 (23): 10277 -- Molecular and Cellular Biology SWAP-70 Regulates c-kit-Induced Mast Cell Activation, Cell-Cell Adhesion, and Migration -- Sivalenka and Jessberger 24 (23): 10277 -- Molecular and Cellular Biology SWAP-70 Regulates c-kit-Induced Mast Cell Activation, Cell-Cell Adhesion, and Migration Department of Gene and Cell Medicine, Mount Sinai School of Medicine, New York mcb.asm.org /cgi/content/abstract/24/23/10277   (259 words)

Stages of Synapse Development Defined by Dependence on F-Actin -- Zhang and Benson 21 (14): 5169 -- Journal of Neuroscience Fishberg Research Center for Neurobiology and Program in Cell Adhesion, The Mount Sinai School of Medicine, New York, New York 10029 of David R. Colman, Mount Sinai School of Medicine (Fannon and Correspondence should be addressed to Dr. Deanna L. Benson, Box 1065/Neurobiology, The Mount Sinai School of Medicine, 1425 www.jneurosci.org /cgi/content/full/21/14/5169   (259 words)

Tyrosine Phosphorylation and p72syk Activation by an Anti-Glycoprotein Ib Monoclonal Antibody -- Yanabu et al. 89 (5): 1590 -- Blood From The First Department of Internal Medicine, Kansai Medical University, Osaka; the Department of Clinical Sciences and Laboratory Medicine, Kansai Medical University, Osaka; the Department of Clinical and Laboratory Medicine, Yamanashi Medical University, Yamanashi, Japan. Von Willebrand factor accelerates platelet adhesion and thrombus formation on a collagen surface in platelet-reduced blood under flow conditions K. Tomokiyo, Y. Kamikubo, T. Hanada, T. Araki, Y. Nakatomi, Y. Ogata, S. Jung, T. Nakagaki, and M. Moroi www.bloodjournal.org /cgi/content/full/89/5/1590   (6856 words)

CAMRC - Scientific Symposium and External Review The goal of CAMRC Symposium 2005 is to highlight cutting edge research from both nationally prominent scientists and UAB researchers in areas broadly relevant to the study of cell adhesion and extracellular matrix biology and the potential application of this knowledge to understanding disease pathogenesis, the development of novel molecular therapeutics, and bioengineering. Paul Bornstein, MD Professor of Biochemistry and Medicine, Past-President, American Society for Matrix Biology Professor of Cell Biology and Medicine, New York University School of Medicine main.uab.edu /camrc/show.asp?durki=71709   (585 words)

eMedicine - Hyperbaric Oxygen Therapy : Article by Michael Neumeister, MD, FRCSC, FACS Oxygen free radicals rise, thromboxane A2 and adhesion molecules are activated, platelet aggregation occurs, and vascular vasoconstriction activity is increased. A flurry of interest in therapeutic hyperbaric medicine was fostered by Dr I. Boerema, who, while in Amsterdam in 1956, reported hyperbaric oxygen (HBO) as an aid in cardiopulmonary surgery, particularly for congenital conditions such as tetralogy of Fallot, transposition of great vessels, and pulmonic stenosis. Unfortunately, as the availability of hyperbaric medicine chambers increased, the indiscriminate and inappropriate use of the chamber for a variety of medical conditions by practitioners searching for a "cure-all" therapy resulted in a backlash from the scientific society, once again tarnishing the credibility of hyperbaric medicine. www.emedicine.com /plastic/topic526.htm   (5864 words)

Hisashi Fujioka, Ph.D. Fujioka served in the Nagoya University School of Medicine as an Assistant Professor from 1984-1991, and then he joined Case Western Reserve University in 1991 as a Research Associate and is currently Assistant Professor of Pathology. Hisashi Fujioka obtained his Bachelor of Science in Pathology with honors from the Kyoto University, Japan in 1976 and completed his Ph.D. in Parasitology at the Nagoya University School of Medicine, Japan in 1984. Dr. Fujioka’s research interests include molecular mechanisms involved in cell adhesion between endothelial cells and Plasmodium falciparum-infected erythrocytes. www.cwru.edu /med/pathology/fac/fujioka.htm   (562 words)

What do we mean by the term "inflammation"? A contemporary basic science update for sports medicine -- Scott et al. 38 (3): 372 -- British Journal of Sports Medicine NK1 receptors mediate leukocyte adhesion in neurogenic inflammation in the rat trachea. Most practicing sports medicine clinicians refer to the concept Inflammation of the subacromial bursa in chronic shoulder pain. bjsm.bmjjournals.com /cgi/content/full/38/3/372   (6209 words)

Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis - Nature Medicine FGF-4 augmented the adhesion of megakaryocytes to BMECs (Fig. Thus, chemokine-induced motility of megakaryocytes facilitates engagement of megakaryocytes with endothelial interjunctional adhesion molecules, thereby supporting thrombopoiesis. The decrease in polyploid megakaryocytes was accompanied by an equivalent decrease in intact sinusoidal vessels (Supplementary Fig. www.nature.com /nm/journal/v10/n1/full/nm973.html   (5561 words)

Tom McIntyre, Professor of Medicine and of Pathology Harris ES, Shigeoka AO, Li W, Adams RH, Prescott SM, McIntyre TM, Zimmerman GA, Lorant DE (2001) A novel syndrome of variant leukocyte adhesion deficiency involving defects in adhesion mediated by beta1 and beta2 integrins. Marathe GK, Harrison KA, Roberts LJ 2nd, Morrow JD, Murphy RC, Tjoelker LW, Prescott SM, Zimmerman GA, McIntyre TM (2001) Identification of platelet-activating factor as the inflammatory lipid mediator in CCl(4)-metabolizing rat liver. Prescott SM, McIntyre TM, Zimmerman GA (2001) Events at the vascular wall: the molecular basis of inflammation. www.bioscience.utah.edu /bc/bcFaculty/mcintyre/mcintyre.html   (5561 words)

Rho-associated Kinase of Chicken Gizzard Smooth Muscle -- Feng et al. 274 (6): 3744 -- Journal of Biological Chemistry Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts First Department of Internal Medicine, Mie University School of Medicine, Tsu, 514-8507, Japan, the Division of Signal Transduction, Nara Institute of Science and Technology, Ikoma 630-0101, Japan, the www.jbc.org /cgi/content/full/274/6/3744   (5243 words)

Involvement of Distinct Cellular Compartments in the Abnormal Lymphoid Organogenesis in Lymphotoxin-{alpha}-Deficient Mice and Alymphoplasia (aly) Mice Defined by the Chimeric Analysis -- Matsumoto et al. 163 (3): 1584 -- The Journal of Immunology The alymphoplasia ( aly) mutation co-segregates with the intercellular adhesion molecule-2 ( Icam-2) on mouse chromosome 11. First Department of Internal Medicine, School of Medicine, Ehime University, Ehime, Japan; Division of Informative Cytology, Institute for Enzyme Research, University of Tokushima, Tokushima, Japan; www.jimmunol.org /cgi/content/full/163/3/1584   (5243 words)

Decoy Receptor 3 Increases Monocyte Adhesion to Endothelial Cells via NF-{kappa}B-Dependent Up-Regulation of Intercellular Adhesion Molecule-1, VCAM-1, and IL-8 Expression -- Yang et al. 174 (3): 1647 -- The Journal of Immunology Decoy Receptor 3 Increases Monocyte Adhesion to Endothelial Cells via NF-{kappa}B-Dependent Up-Regulation of Intercellular Adhesion Molecule-1, VCAM-1, and IL-8 Expression -- Yang et al. Department of Pharmacology, College of Medicine, National Taiwan University, Articles by Yang, C.-R. Articles by Lin, W.-W. The Journal of Immunology, 2005, 174: 1647-1656. www.jimmunol.org /cgi/content/abstract/174/3/1647   (320 words)

Essential Involvement of IFN-{gamma} in Clostridium difficile Toxin A-Induced Enteritis -- Ishida et al. 172 (5): 3018 -- The Journal of Immunology Adhesion molecules intercellular adhesion molecule-1 (ICAM-1), ICAM-3 and B7 are not expressed by epithelium in normal or inflamed colon. Center, Osaka University Graduate School of Medicine, Osaka, data were expressed as units per dry weight (grams). www.jimmunol.org /cgi/content/full/172/5/3018   (3924 words)

Intercellular calcium communication regulates platelet aggregation and thrombus growth -- Nesbitt et al. 160 (7): 1151 -- The Journal of Cell Biology The ability of platelets to form stable adhesion contacts with Australian Centre for Blood Diseases, Department of Medicine, Monash University, Box Hill Hospital, Victoria 3128, Australia Address correspondence to Shaun P. Jackson, Australian Centre for Blood Diseases, Department of Medicine, Monash University, Box Hill Hospital, Arnold St., Box Hill, Melbourne, Victoria 3128, Australia. www.jcb.org /cgi/content/abstract/160/7/1151   (558 words)

Leukocyte Activation and Flow Behavior in Rat Skeletal Muscle in Sepsis -- PIPER et al. 157 (1): 129 -- American Journal of Respiratory and Critical Care Medicine Leukocyte adhesion to venular endothelium is shear-rate dependent (21). and anti-CD11b) that inhibit leukocyte adhesion to postcapillary In animal models of endotoxemia, sepsis is associated with the accumulation of leukocytes and altered microvascular perfusion. ajrccm.atsjournals.org /cgi/content/full/157/1/129   (3498 words)

Coordinated Redistribution of Leukocyte LFA-1 and Endothelial Cell ICAM-1 Accompany Neutrophil Transmigration -- Shaw et al. 200 (12): 1571 -- The Journal of Experimental Medicine Tumor necrosis factor-alpha-induced leukocyte adhesion and microvessel permeability. Adhesion-activating phorbol ester increases the mobility of leukocyte integrin LFA-1 in cultured lymphocytes. JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes. www.jem.org /cgi/content/full/200/12/1571   (5390 words)

Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway -- Okamoto et al. 155 (5): 755 -- The Journal of Cell Biology Address correspondence to Hideyuki Saya, Department of Tumor Genetics and Biology, Kumamoto University School of Medicine, 2-2-1 Honjo, Kumamoto 860-0811, Japan. Department of Tumor Genetics and Biology, Kumamoto University School of Medicine, 2-2-1 Honjo, Kumamoto 860-0811, Japan CD44 is a widely distributed cell surface adhesion molecule www.jcb.org /cgi/content/abstract/155/5/755   (5390 words)

Effect of ADCON-L on adjustable strabismus surgery in rabbits -- Choi et al. 85 (1): 80 -- British Journal of Ophthalmology In search of a way to prevent postoperative adhesion after strabismus surgery, an animal study was performed to assess the Department of Ophthalmology, College of Medicine, Chungbuk National University, Cheongju, Korea, Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Korea bjo.bmjjournals.com /cgi/content/full/85/1/80   (2502 words)

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