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Topic: Adhesion molecule

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cell adhesion proteins

factor of adhesion

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Bender MedSystems: ICAM-1 Soluble intercellular adhesion molecule-1 in cerebrospinal fluid: an indicator for the inflammatory impairment of the blood-cerebrospinal fluid barrier. Intercellular adhesion molecule-1 concentration in sera of patients with acute and chronic liver disease: relationship to disease activity and cirrhosis. Expression of the adhesion molecule ICAM-1 on alveolar macrophages and in serum in extrinsic allergic alveolitis. www.medsystems.at /98.html

Cell adhesion - Wikipedia, the free encyclopedia Cell adhesion generally involves protein molecules at the surface of cells, so the study of cell adhesion involves cell adhesion proteins and the molecules that they bind to. There are families of cell adhesion proteins that can be characterized in terms of the structure of the adhesion proteins and their ligands. Regulation of cell adhesion proteins is important during embryonic development for the process of morphogenesis. en.wikipedia.org /wiki/Cell_adhesion

Soluble Intercellular Adhesion Molecule-1 (sICAM-1) and Interferon-Gamma in Bronchoalveolar Lavage Fluid from Children with Airway Diseases -- MARGUET et al. 162 (3): 1016 -- American Journal of Respiratory and Critical Care Medicine Intercellular adhesion molecule-1 (ICAM-1) in the pathogenesis of asthma. The expression of intercellular adhesion molecule-1 and the 1-integrins in asthma. Intercellular adhesion molecule-1 (ICAM-1) and endothelial leucocyte adhesion molecule-1 (ELAM-1) expression in the bronchial mucosa of normal and asthmatic subjects. www.ajrccm.org /cgi/content/full/162/3/1016

Intercellular Adhesion Molecule-5 Induces Dendritic Outgrowth by Homophilic Adhesion -- Tian et al. 150 (1): 243 -- The Journal of Cell Biology Release of soluble ICAM-5, a neuronal adhesion molecule, in acute encephalitis Intercellular Adhesion Molecule-5 Induces Dendritic Outgrowth by Homophilic Adhesion Intercellular Adhesion Molecule-5 Induces Dendritic Outgrowth by Homophilic Adhesion -- Tian et al. www.jcb.org /cgi/content/full/150/1/243

Gene Information Olson KK, et al reported prolactin-induced expression of intercellular adhesion molecule-1 and the accumulation of monocytes/macrophages during regression of the rat corpus luteum and conclude that ICAM-1 expression and monocyte/macrophage accumulation are associated with prolactin-induced luteal regression in the rat and that these aspects are not influenced by testosterone. Expression of intercellular adhesion molecule-1 (ICAM-1) and the accumulation of monocytes/macrophages are inflammatory events that occur during PRL (PRL)-induced regression of the rat corpus luteum. Intercellular adhesion molecule-1 (ICAM1) is a ligand for lymphocyte-function associated (LFA) antigens. ovary.stanford.edu /4_display.html?rec=965

molecule Expression of intercellular adhesion molecule 1 on pancreatic beta-cells accelerates beta-cell destruction by cytotoxic T-cells in murine autoimmune diabetes. Circulating intercellular adhesion molecule-1 and E-selectin in patients with acute coronary syndrome. Increased expression of leukocyte function associated antigen-1 (LFA-1) and intercellular adhesion molecule-1 (ICAM-1) by alveolar macrophages of patients with pulmonary sarcoidosis. www.infoplease.com /id/A0833627

Endometrial Release of Soluble Intercellular Adhesion Molecule 1 and Endometriosis: Relationship to the Extent of the Disease -- VIGANÒ et al. 95 (1): 115 -- Obstetrics & Gynecology of intercellular adhesion molecule 1 with extent of endometriosis. Endometrial Release of Soluble Intercellular Adhesion Molecule 1 and Endometriosis: Relationship to the Extent of the Disease -- VIGANÒ et al. Concentration of soluble intercellular adhesion molecule-1 in serum samples from patients with endometriosis collected during the luteal phase of the menstrual cycle www.greenjournal.org /cgi/content/abstract/95/1/115

Biologically Active Intercellular Adhesion Molecule-1 Is Shed as Dimers by a Regulated Mechanism in the Inflamed Pleural Space -- Melis et al. 167 (8): 1131 -- American Journal of Respiratory and Critical Care Medicine Intercellular adhesion molecule-1 (ICAM-1) is an adhesion molecule Intercellular adhesion molecule-1 dimerization and its consequences for adhesion mediated by lymphocytes function associated-1. The native structure of intecellular adhesion molecule-1 (ICAM-1) is a dimer: correlation with binding to LFA-1. ajrccm.atsjournals.org /cgi/content/full/167/8/1131

Intercellular Adhesion Molecule-1 (ICAM-1)* It functions as a costimulatory molecule on antigen-presenting cells to activate MHC class II restricted T-cells, and on other cell types in association with MHC class I to activate cytotoxic T-cells. Its ligands are the membrane-bound integrin receptors LFA-1 and Mac-1 on leukocytes, CD43, the soluble molecule fibrinogen, the matrix factor hyaluronan, rhinoviruses, and Plasmodium falciparum malaria-infected erythrocytes. It can be induced in a cell-specific manner by several cytokines, for example, tumor necrosis factor-alpha, interleukin-1, and interferon-gamma, and inhibited by glucocorticoids. www.hsc.wvu.edu /micro/IRI/tsld036.htm

Intercellular Adhesion Molecule-1 Gene Polymorphisms in Behçet's Disease Intercellular adhesion molecule 1 (ICAM-1) is strongly expressed in vascular endothelial cells and perivascular inflammatory infiltrates in immunopathologic studies of Behçet's disease (BD) lesions. Intercellular Adhesion Molecule-1 Gene Polymorphisms in Behçet's Disease ICAM-1 genes may contribute to the inflammatory events responsible for the vessel damage in BD. www.jrheum.com /abstracts/abstracts01/1283.html

The role of alpha 4 integrin and intercellular adhesion molecule-1 (ICAM-1) in murine experimental autoimmune thyroiditis. These results suggest that these two adhesion molecules exhibit differential functional roles in the modulation of EAT disease severity and that alpha 4-VCAM interactions may be of particular importance in trafficking of effector cells to the thyroid. The role of alpha 4 integrin and intercellular adhesion molecule-1 (ICAM-1) in murine experimental autoimmune thyroiditis. This investigation was undertaken to begin to define the roles of alpha 4 integrin, and intercellular adhesion molecule-1 (ICAM-1) in the migration of CD4+ and CD8+ T cells to the thyroid in EAT. www.aegis.com /aidsline/1997/mar/M9731088.html

N-Acetyl-D-galactosamine specific lectin of Eikenella corrodens induces intercellular adhesion molecule-1 (ICAM-1) production by human oral epithelial cells -- YAMADA et al. 51 (12): 1080 -- Journal of Medical Microbiology Adhesion of T lymphoblasts to epidermal keratinocytes is regulated by interferon gamma and is mediated by intercellular adhesion molecule-1 (ICAM-1). Adhesion molecule expression in chronic inflammatory periodontal disease tissue. Levels of soluble adhesion molecules and cytokines in patients with septic multiple organ failure. jmm.sgmjournals.org /cgi/content/full/51/12/1080

Immunohistochemical Detection of Adhesion Molecules Intercellular Adhesion Molecule-1 and E-Selectin in Formalin-Fixed, Paraffin-Embedded Mouse Tissues Expression of adhesion molecules on the endothelium of normal tissue vessels and vascular tumors. Crucial role of 55kilodalton TNF receptor in TNFinduced adhesion molecule expression and leukocyte organ infiltration. Kinetic expression of endothelial adhesion molecules and relationship to leukocyte recruitment in two cutaneous models of inflammation. info.med.yale.edu /labinvest/abstracts/97months/9711nov/1197bm2.html

NEW EMBO MEMBER'S REVIEW: Changing neighbours, changing behaviour: cell adhesion molecule-mediated signalling during tumour progression -- Christofori 22 (10): 2318 -- The EMBO Journal Cavallaro,U. and Christofori,G. (2001) Cell adhesion in tumor invasion and metastasis: loss of the glue is not enough. adhesion during physiological processes ( DeLuca et al., 1999). Hirohashi,S. (1998) Inactivation of the E-cadherin-mediated cell adhesion system in human cancers. embojournal.npgjournals.com /cgi/content/full/22/10/2318

Fimbria-Dependent Activation of Cell Adhesion Molecule Expression in Porphyromonas gingivalis-Infected Endothelial Cells -- Khlgatian et al. 70 (1): 257 -- Infection and Immunity The expression of adhesion molecules ICAM-1, PECAM, and E-selectin in human atherosclerosis. Intimate adhesion of Neisseria meningitides to human epithelial cells is under the control of the crgA gene, a novel LysR-type transcriptional regulator. Cells were harvested at 2 h for FACS analysis (upper panels) or confocal microscopy (lower panels) for the detection of P-selectin (A) and E-selectin (B) expression. iai.asm.org /cgi/content/full/70/1/257

Adhesion molecules L1 is a neural cell to cell adhesion molecule important in developing nerve processes ICAM (intercellular adhesion molecules) may be expressed on activated endothelial cells. Cells can be influenced heavily by the environment (matrix proteins) because of the presence of transmembrane glycoproteins called Integrins. cellbio.utmb.edu /cellbio/adhesion_molecules.htm

Human protein: P32004 - Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen). EMBL Bioinformatic Harvester The neural cell adhesion molecule L1: genomic organisation and differential splicing is conserved between man and the pufferfish Fugu. Cell adhesion molecule with an important role in the development of the nervous system. cell adhesion molecule with an important role in the development of the nervous system. harvester.embl.de /harvester/P320/P32004.htm

Flavones & Cell Adhesion The effects of flavones, luteolin and apigenin, on adhesion of THP-1 monocytes to the TNF--activated HUVEC, protein expression and mRNA levels of vascular cell adhesion molecule-1 (VCAM-1), intracellular cell adhesion molecule-1 (ICAM-1) and E-selectin, and nuclear appearance and DNA binding activity of NF-B were determined. The inhibition of endothelial CAM induction by flavones is mediated by their interference with the NF-B-dependent transcription pathway. This study examined the effects of flavones on the induction of CAM and the translocation and DNA binding of nuclear factor-B (NF-B) in TNF--activated human umbilical vein endothelial cells (HUVEC). www.annieappleseedproject.org /flavcelad.html

molecule on Encyclopedia.com Increased Levels of Soluble Vascular Cell Adhesion Molecule 1 Are Associated With Risk of Cardiovascular Mortality in Type 2 Diabetes. Expression of intercellular adhesion molecule 1 on pancreatic beta-cells accelerates beta-cell destruction by cytotoxic T-cells in murine autoimmune diabetes. Circulating vascular cell adhesion molecule-1 (VCAM-1) in atherosclerotic NIDDM patients. www.encyclopedia.com /html/m1/molecule.asp

interleukin.html In the present study, the roles of individual CD11/CD18 integrins and endothelial adhesion molecules were examined using blocking mAbs and peptides. Adhesion of these cells to the RGD site was likely mediated by alpha 5 beta 1 integrin which was identified in the cell membrane of both cell lines, but present in low copy number in B6Sut cells. AB: Adhesion of cancer cells to endothelium is thought to be a prerequisite to extravasation during the haematogenous phase of metastasis, and is enhanced after perturbation of the endothelium by interleukin-1 (IL-1). www.iub.edu /~pietsch/interleukin.html

Genetic Evidence for Functional Redundancy of Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1): CD31-Deficient Mice Reveal PECAM-1-Dependent and PECAM-1-Independent Functions -- Duncan et al. 162 (5): 3022 -- The Journal of Immunology Platelet endothelial cell adhesion molecule-1 (PECAM-1) hemophilic adhesion is mediated by immunoglobulin-like domains 1 and 2 and depends on the cytoplasmic domain and the level of surface expression. Neutrophil platelet endothelial cell adhesion molecule-1 participates in neutrophil recruitment at inflammatory sites and is down-regulated after leukocyte extravasation. The protein tyrosine phosphatase SHP-2 binds platelet/endothelial cell adhesion molecule-1 (PECAM-1) and forms a distinct signaling complex during platelet aggregation: evidence for a mechanistic link between PECAM-mediated and integrin-mediated cellular signaling. www.jimmunol.org /cgi/content/full/162/5/3022

Annual Reviews -- Chothia and Jones ( Biochemisty 66: 823) Shown here is part of one row of adhesion molecules; rows with the same structure are also formed normal to the plane of the drawing. Adhesion molecules on the surface of leukocytes facilitate VCAM-1 ( 115) is one of a subgroup of IgSF-type cell adhesion indy2.fisfar.uah.es /~fgago/Public/AnnReviews/HTML/Chothia.html

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 on Murine Dendritic Cells Is a Potent Regulator of T Cell Stimulation -- Kammerer et al. 166 (11): 6537 -- The Journal of Immunology The tumor growth-inhibiting cell adhesion molecule CEACAM1 (C-CAM) is differently expressed in proliferating and quiescent epithelial cells and regulates cell proliferation. The N-domain of the human CD66a adhesion molecule is a target for Opa proteins of Neisseria meningitidis and Neisseria gonorrhoeae. is responsible for the cell-cell adhesion activity of CEACAM1. www.jimmunol.org /cgi/content/full/166/11/6537

Soluble intercellular adhesion molecule-1 (s-ICAM-1/s-CD54) in diffuse large B-cell lymphoma: association with clinical characteristics and outcome -- Terol et al. 14 (3): 467 -- Annals of Oncology Serum levels of soluble intercellular adhesion molecule-1 are increased in chronic B-lymphocyte leukemia and correlate with clinical stage and prognostic markers. Serum levels and differential expression of intercellular adhesion molecule-1 in childhood leukemia and malignant lymphoma: prognostic importance and relationship with survival. Expression of leukocyte function-associated antigen-1 and 7F7-antigen, an adhesion molecule related to intercellular adhesion molecule-1 (ICAM-1) in non-Hodgkin’s lymphoma and leukemias: possible influence on growth pattern and leukaemic behaviour. annonc.oxfordjournals.org /cgi/content/full/14/3/467

Intercellular Adhesion Molecule 1 Gene Polymorphisms in Graves' Disease -- Kretowski et al. 88 (10): 4945 -- Journal of Clinical Endocrinology & Metabolism Intercellular Adhesion Molecule 1 Gene Polymorphisms in Graves’ Disease Intercellular Adhesion Molecule 1 Gene Polymorphisms in Graves' Disease -- Kretowski et al. Wenisch C, Myskiw D, Gessl A, Graninger W 1995 Circulating selectins, intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in hyperthyroidism. jcem.endojournals.org /cgi/content/full/88/10/4945

SciMedWeb® - INTERCELLULAR ADHESION MOLECULE-1 (ICAM-1) Tumor cell invasion of Matrigel membranes was partially blocked by either anti-CD44 or anti-CD54 antibodies, indicating a role for these adhesion molecules in the invasion process (Xu F.J. et al., 1997). Heregulin treatment also increased adhesion of SKBR3 cells to plastic and increased invasiveness of tumor cells into Matrigel membranes while increasing expression of the CD44 (HCAM) and CD54 (ICAM-1) adhesion molecules. The molecule was identified in formalin-fixed, paraffin-embedded primary tumors, and the relationship to clinicopathological factors and prognosis was analyzed. www.geocities.com /m.lacroix/marqueurs/icam1.htm

Indomethacin induced gastropathy in CD18, intercellular adhesion molecule 1, or P-selectin deficient mice -- Morise et al. 45 (4): 523 -- Gut To optimise a mouse model of NSAID induced gastropathy and to evaluate the importance of adhesion molecules using adhesion Certain leucocyte and endothelial cell adhesion molecules are important determinants for full expression of indomethacin induced Gastropathy was induced in C57BL/6 mice or their adhesion molecule deficient counterparts via oral administration of indomethacin gut.bmjjournals.com /cgi/content/abstract/45/4/523

Induction of intercellular adhesion molecule-1 and E-selectin mRNA in heart and skeletal muscle of pediatric patients undergoing cardiopulmonary bypass -- Kilbridge et al. 107 (5): 1183 -- The Journal of Thoracic and Cardiovascular Surgery of endothelial adhesion molecules in the inflammatory response Induction of intercellular adhesion molecule-1 and E-selectin mRNA in heart and skeletal muscle of pediatric patients undergoing cardiopulmonary bypass -- Kilbridge et al. Induction of intercellular adhesion molecule-1 and E-selectin mRNA in heart and skeletal muscle of pediatric patients undergoing cardiopulmonary bypass jtcs.ctsnetjournals.org /cgi/content/abstract/107/5/1183

Dexamethasone inhibition of leucocyte adhesion to rat mesenteric postcapillary venules: role of intercellular adhesion molecule 1 and KC -- Tailor et al. 45 (5): 705 -- Gut Dexamethasone inhibition of leucocyte adhesion to rat mesenteric postcapillary venules: role of intercellular adhesion molecule 1 and KC Dexamethasone inhibition of leucocyte adhesion to rat mesenteric postcapillary venules: role of intercellular adhesion molecule 1 and KC -- Tailor et al. of endogenous ICAM-1 and KC contributes to leucocyte adhesion to inflamed mesenteric vessels. gut.bmjjournals.com /cgi/content/abstract/45/5/705

Vitreous intercellular adhesion molecule 1 in uveitis complicated by retinal detachment -- Webster et al. 82 (4): 438 -- British Journal of Ophthalmology Soluble intercellular adhesion molecule-1 (sICAM-1) as a marker of disease relapse in idiopathic uveoretinitis. Vitreous intercellular adhesion molecule 1 in uveitis complicated by retinal detachment Vitreous intercellular adhesion molecule 1 in uveitis complicated by retinal detachment -- Webster et al. bjo.bmjjournals.com /cgi/content/full/82/4/438

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