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| | Carbon Chemistry |
 | | In 1845, for instance, Adolph Wilhelm Hermann Kolbe (1818-1884), a pupil of Wohler's, succeeded in synthesizing acetic acid, an indubitably organic substance. |
 | | Furthermore, he synthesized it by a method which showed that a clear line of chemical change could be drawn from the constituent elements, carbon, hydrogen, and oxygen, to the final product, acetic acid. |
 | | With Berthelot, crossing the line from inorganic to organic ceased to be a thrilling intrusion upon the "forbidden", and became purely routine. |
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