
	Where results make sense

Topic: Adrenoceptor

Related Topics

Adrenergic receptor

Bronchodilator

Adrenaline

List of compounds

Vital capacity

Food

Epinephrine

In the News (Tue 29 Dec 09)

Northern Trust

Marvin Harrison

Peter Chernin

Gary Locke

Match Play

Penelope Cruz

Mickey Rourke

AR Rahman

Danny Boyle

Hugh Jackman

	Complex Scenario
		adrenoceptor sub-classifications are further supported by the development of subtype selective agonists and antagonists.
		adrenoceptors is the relative potencies of adrenaline and noradrenaline, with the two catecholamines being equipotent at the
		adrenoceptor subtypes activate adenylyl cyclase as a primary mechanism for signal transduction.
	www.kfunigraz.ac.at /~binder/science/complex.html (1317 words)

	PharmiWeb: Feature: HMP-12 an adrenoceptor antagonist for the treatmen (Site not responding. Last check: 2007-10-22)
		Here we focus on the involvement of adrenoceptors in male and female sexual physiology, and in the pathophysiology of erectile dysfunction and female arousal disorder.
		The adrenoceptor antagonist, phentolamine has been launched for the treatment of erectile dysfunction and is in clinical development for the treatment of female arousal disorder.
		We conclude that although adrenoceptor antagonists are unlikely to replace PDE5 inhibitors as treatments of mild erectile dysfunction, such molecules may provide a valuable adjunct to PDE5 inhibitors (or indeed apomorphine) in treating the 50% of patients with moderate to severe disease that are poorly responsive to sildenafil monotherapy.
	www.pharmiweb.com /features/feature.asp?ROW_ID=236 (529 words)

	[No title] (Site not responding. Last check: 2007-10-22)
		This demonstrates that alpha-2B- adrenoceptors mediate vascular contraction.
		This effect has not been seen with alpha-2B-nonselective alpha-2- adrenoceptor antagonists, because antagonism of alpha-2A-adrenoceptors increases sympathetic outflow, cardiac output and blood pressure.
		A method for the treatment or prevention of a disease mediated by the alpha-2B- adrenoceptor in a mammal, said method comprising administering to said mammal an effective amount of a selective alpha-2B-adrenoceptor antagonist, wherein said antagonist is a compound selected from the group consisting of compounds A, B, C, D and E disclosed in Scheme
	www.wipo.int /cgi-pct/guest/getbykey5?KEY=01/58454.010816&ELEMENT_SET=DECL (2448 words)

	{alpha}1-Adrenoceptor Subtypes in Rat Epididymis and the Effects of Sexual Maturation -- Queiróz et al. 66 (2): ... (Site not responding. Last check: 2007-10-22)
		Sympathetic co-transmission to the cauda epididymis of the rat: characterization of posjunctional adrenoceptors and purinoceptors.
		adrenoceptor mediating the contractile response of rat aorta to noradrenaline.
		Structure activity relationships of a series of buspirone analogs at alpha-1 adrenoceptors: further evidences that rat aorta alpha-1 adrenoceptors are of the alpha-1D-subtype.
	www.biolreprod.org /cgi/content/full/66/2/508 (4428 words)

	alpha 2-Adrenoceptor-Mediated Presynaptic Modulation of GABAergic Transmission in Mechanically Dissociated Rat ...
		Adrenoceptors are coupled to guanosine 5'-triphosphate (GTP)-binding proteins (G-proteins) (Bylund et al.
		Nicholas AP, Hokfelt T, and Pieribone VA. The distribution and significance of CNS adrenoceptors examined with in situ hybridization.
		Medial preoptic alpha-2 adrenoceptors in the regulation of sleep-wakefulness.
	jn.physiology.org /cgi/content/full/89/3/1640 (5157 words)

	Association of distinct {alpha}2 adrenoceptor and serotonin transporter polymorphisms with constipation and somatic ...
		The release of serotonin from rat duodenal enterochromaffin cells by adrenoceptor agonists studied in vitro.
		Alpha 2C adrenoceptors mediate contractile responses to norepinephrine in the human saphenous vein.
		Genetic alteration of the alpha2 adrenoceptor subtype c in mice affects the development of behavioral despair and stress-induced increases in plasma corticosterone levels.
	gut.bmjjournals.com /cgi/content/full/53/6/829 (4374 words)

	Department of Biological & Biomedical Sciences - Dr Allan MacDonald (Site not responding. Last check: 2007-10-22)
		In recent years this has focused on vascular adrenoceptors, both alpha- and beta-adrenoceptors.
		Our previous work has also shown that the response to noradrenaline in rat femoral resistance arteries is also mediated by the alpha1A -adrenoceptor (Jarajapu et al., 2001b).
		We found that the predominant subtype activated by both neuronally-released and exogenous noradrenaline in rat femoral artery resistance arteries was the alpha1A-adrenoceptor.
	www.gcal.ac.uk /sls/Bio/research/staff/physiology/MacDonald.html (1030 words)

	{beta}2 adrenoceptor promoter polymorphisms: extended haplotypes and functional effects in peripheral blood mononuclear ...
		adrenoceptor promoter polymorphisms: extended haplotypes and functional effects in peripheral blood mononuclear cells
		adrenoceptor polymorphisms –367 and –47 in the 5' flanking region, loci 16 and 27 in the coding region (n = 96)
		adrenoceptor levels of receptor expression (Bmax), receptor affinity (Kd), and the ability of isoprenaline to stimulate cyclic AMP formation (Emax)
	thorax.bmjjournals.com /cgi/content/full/57/1/61 (3032 words)

	Modulation of Relative Intrinsic Activity of Agonists at the Alpha-2A Adrenoceptor by Mutation of Residue 351 of G ...
		Modulation of Relative Intrinsic Activity of Agonists at the Alpha-2A Adrenoceptor by Mutation of Residue 351 of G Protein Gi1alpha -- Jackson et al.
		Modulation of Relative Intrinsic Activity of Agonists at the Alpha-2A Adrenoceptor by Mutation of Residue 351 of G Protein G
		Affinity of alpha-2 adrenoceptor ligands at alpha-2A adrenoceptor-G
	molpharm.aspetjournals.org /cgi/content/full/55/2/195 (4167 words)

	Clore Laboratory News: Beta-adrenoceptor agonists with atypical pharmacology
		M) both appeared to act via the β2-adrenoceptor to produce opposing effects on 2-deoxyglucose uptake (BRL 37344 stimulated, clenbuterol inhibited).
		M, these compounds produced similar stimulatory responses which were equally blocked with similar potency by β1 (atenolol) and β2 (ICI 118551) adrenoceptor antagonists.
		This suggests that these effects are mediated by a β-adrenoceptor with atypical pharmacology.
	www.buckingham.ac.uk /clore/news/25aug03.html (228 words)

	Diabetes: CL-316,243, a beta-3-specific adrenoceptor agon... @ HighBeam Research (Site not responding. Last check: 2007-10-22)
		CL-316,243, a beta-3-specific adrenoceptor agonist, enhances insulin-stimulated glucose disposal in nonobese rats.
		Diabetes; 8/1/1997; Horton, Edward S. Administration of the murine-selective [[Beta].sub.3] adrenoceptor agonist CL-316,243 corrects obesity and elevated blood glucose in diabetic rodents.
		This antiobesity effect is attributed to an increase in the thermogenic activity of brown adipose tissue (BAT).
	www.highbeam.com /library/doc0.asp?DOCID=1G1:19652411&refid=holomed_1 (5172 words)

	Vascular Adrenoceptors: An Update -- Guimarães and Moura 53 (2): 319 -- Pharmacological Reviews
		The present review aims at updating adrenoceptors in blood vessels, particularly on a functional point of view.
		The adrenoceptors are the cell membrane sites through which noradrenaline and adrenaline act as important neurotransmitters
		It is important to underline that many of the advances made in the last years in the field of receptors in general and on
	pharmrev.aspetjournals.org /cgi/content/full/53/2/319 (4130 words)

	adrenoceptor - OneLook Dictionary Search
		Tip: Click on the first link on a line below to go directly to a page where "adrenoceptor" is defined.
		adrenoceptor : Dorland's Illustrated Medical Dictionary [home, info]
		Phrases that include adrenoceptor: alpha adrenoceptor, beta adrenoceptor, adrenoceptor antagonist
	www.onelook.com /?w=adrenoceptor (96 words)

	Long- and short-acting beta2 adrenoceptor agonists: interactions in human contracted bronchi -- Molimard et al. 11 (3): ...
		Long- and short-acting beta2 adrenoceptor agonists: interactions in human contracted bronchi -- Molimard et al.
		Long- and short-acting beta2 adrenoceptor agonists: interactions in human contracted bronchi
		The aim of this study was to systematically compare the interaction of the long-acting beta2-adrenoceptor agonists formoterol and salmeterol with short-acting beta2-adrenoceptor agonists in contracted human bronchi.
	erj.ersjournals.com /cgi/content/abstract/11/3/583 (434 words)

	An alpha 1A/alpha 1L-Adrenoceptor Mediates Contraction of Canine Subcutaneous Resistance Arteries -- Argyle and McGrath ...
		, in accordance with the adrenoceptor nomenclature committee
		adrenoceptor of low affinity for prazosin and equivalent affinity of prazosin
		- adrenoceptor subtypes in the mesenteric vasculature of the rat.
	jpet.aspetjournals.org /cgi/pmidlookup?view=full&pmid=11046098 (3900 words)

	{alpha}1- and {beta}-adrenoceptor stimulation differentially activate p38-MAPK and atrial natriuretic peptide ...
		ANP immunolocalisation in the ventricle of isolated amphibian heart perfused with phenylephrine (PHE) and various adrenoceptor antagonists or SB203580.
		ANP immunolocalisation in the ventricle of isolated amphibian heart perfused with isoproterenol (ISO) and various adrenoceptor antagonists or SB203580.
		Hieble, J. and Ruffolo, R. Subclassification of ß adrenoceptors: ß-adrenoceptors: Mol.
	jeb.biologists.org /cgi/content/full/205/16/2387 (4437 words)

	Asthma exacerbations during long term beta agonist use: influence of beta 2 adrenoceptor polymorphism -- Taylor et al. ...
		Asthma exacerbations during long term beta agonist use: influence of beta 2 adrenoceptor polymorphism -- Taylor et al.
		adrenoceptor influence receptor function in vitro and asthma phenotypes in vivo.
		Cross tolerance to salbutamol occurs independently of {beta}2 adrenoceptor genotype-16 in asthmatic patients receiving regular formoterol or salmeterol
	thorax.bmjjournals.com /cgi/content/abstract/55/9/762 (878 words)

	Effects of Vasodilatory ß-Adrenoceptor Antagonists on Endothelium-Derived Nitric Oxide Release in Rat Kidney -- Kakoki ...
		Effects of Adrenoceptor Antagonists and 5-Hydroxytryptamine Receptor Antagonists on the Action of ß-Blockers in Isolated Kidney
		Effects of Adrenoceptor Agonists and a 5-HT Receptor Agonist in Isolated Kidney
		-selective adrenoceptor antagonist, on voltage-dependent calcium channels in guinea-pig artery and vein.
	hyper.ahajournals.org /cgi/content/full/33/1/467 (2502 words)

	Functional beta 3-Adrenoceptor in the Human Heart -- Gauthier et al. 98 (2): 556 -- Journal of Clinical Investigation
		Trendelenburg (1994) International union of pharmacology nomenclature of adrenoceptors.
		Berlan (1992) The positive chronotropic effect induced by BRL 37344 and CGP 12177, two beta-3 adrenoceptor agonists, does not involve cardiac beta adrenoceptors but baroreflex mechanisms.
		Berlan (1993) Beta 3-adrenoceptors in dog adipose tissue: studies on their involvement in the lipomobilizing effect of catecholamines.
	www.jci.org /cgi/content/full/98/2/556 (4494 words)

	Priming of Excitatory Synapses by {alpha}1 Adrenoceptor-Mediated Inhibition of Group III Metabotropic Glutamate ...
		adrenoceptor mediated and PKC dependent The excitatory effects
		adrenoceptor activates phospholipase C through the Gq family of G-proteins, resulting in phosphatidylinositol metabolism,
		Adrenoceptor; PLC, phospholipase C; IP inositol triphosphate; DAG, diacylglycerol; PKC, protein kinase C; RRP, readily releasable pool; NA, noradrenaline.
	www.jneurosci.org /cgi/content/full/23/15/6223 (5796 words)

	Differential Control of Adrenal and Sympathetic Catecholamine Release by {alpha}2-Adrenoceptor Subtypes -- Brede et al. ...
		ADRENOCEPTORS FORM THE interface between the endogenous catecholamines,
		adrenoceptors on effector cells, but also stimulates presynaptic
		Bylund DB, Eikenberg DC, Hieble JP, Langer SZ, Lefkowitz RJ, Minneman KP, Molinoff PB, Ruffolo RR, Trendelenburg U 1994 International Union of Pharmacology nomenclature of adrenoceptors.
	mend.endojournals.org /cgi/content/full/17/8/1640 (2593 words)

	Adrenoceptor
		The purpose of the adrenoceptor web site is to provide students and researchers with information on adrenergic receptors.
		In addition, we have asked respected scientists in the field of adrenoceptors to contribute short articles on current topics.
		If you have any comments or enquiries please send an E-mail to
	www.adrenoceptor.com /homemail5.html (78 words)

	OriGene - Antibodies - Beta-3 Adrenoceptor
		Researchers who bought this antibody have also purchased:
		The Beta-3 Adrenoceptor (ADRB3) is an Adrenergic Receptor that stimulates lipolysis and increases fatty acids in the blood.
		Stimulation of the beta-3 adrenoceptor leads to lipolysis in white adipocytes and nonshivering thermogenesis in brown fat.
	www.origene.com /antibody/TA200344.aspx (139 words)

	Atypical beta -adrenergic effects on insulin signaling and action in beta 3-adrenoceptor-deficient brown adipocytes -- ...
		of this adrenoceptor results in an increase in lipolysis and energy
		Regulation of energy balance in rodents is mediated
		Thus the novel atypical adrenoceptor may employ different signaling
	ajpendo.physiology.org /cgi/content/full/283/1/E146 (3491 words)

	IB
		What is meant by "desensitization" as it applies to adrenoceptor regulation?
		Understand in general how changes in structure can affect receptor selectivity and pharmacokinetics of adrenoceptor agonists.
		Understand the metabolism of norepinephrine and the other catecholamines
	www.kumc.edu /research/medicine/pharmacology/CAI/iib.htm (1087 words)

	A putative {beta}2-adrenoceptor from the rainbow trout (Oncorhynuchus mykiss): Molecular characterization and ... (Site not responding. Last check: 2007-10-22)
		little attention, however, has focused on adrenoceptors from
		Abbreviations: AR, adrenoceptor; GSP, gene specific primer; AUAP, abridged universal amplification primer; CGP-12177, ((–)-4-(3-t-butylamino-2-hydroxypropoxy-[5,7-
		Keen, J.E., Vianzon, D.M., Farrell, A.P. and Tibbits, G.F. (1993) Thermal acclimation alters both adrenergic sensitivity and adrenoceptor density in cardiac tissue of rainbow trout.
	content.febsjournal.org /cgi/content/full/268/24/6465 (3413 words)

	Feedback Inhibition of Catecholamine Release by Two Different {alpha}2-Adrenoceptor Subtypes Prevents Progression of ... (Site not responding. Last check: 2007-10-22)
		To date, 9 different adrenoceptor subtypes have been identified
		Transgenic mouse models have recently gained great value
		to dissect the specific function of individual adrenoceptor
	circ.ahajournals.org /cgi/content/full/106/19/2491 (2795 words)

	Regulation of beta -Adrenoceptor Signaling in Cardiac Function and Disease -- Dzimiri 51 (3): 465 -- Pharmacological ...
		showing that both PKA and PKC act as hubs for sorting adrenoceptor
		Regulation of the Ras/Raf/MAP kinase pathway by adrenoceptors.
		Both PKC and PKA serve as hubs for the cross-regulation of the adrenoceptors, but cross-talk may occur already at the second messenger levels.
	pharmrev.aspetjournals.org /cgi/content/full/51/3/465 (6971 words)

	GPCRDB fragments
		(386 AA) Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2Badrenoreceptor) (F
		(392 AA) Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2Badrenoreceptor) (F
		(382 AA) Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2Badrenoreceptor) (F
	www.gpcr.org /7tm/seq/fragments/DRfrag.html (1703 words)

	958. Adrenoceptor, beta- blocking agent: Carazolol (WHO Food Additives Series 43)
		Adrenoceptor, beta- blocking agent: Carazolol (WHO Food Additives Series 43)
		INTERNATIONAL PROGRAMME ON CHEMICAL SAFETY WORLD HEALTH ORGANIZATION TOXICOLOGICAL EVALUATION OF CERTAIN VETERINARY DRUG RESIDUES IN FOOD
		Rome, Food and Agriculture Organization of the United Nations (unpublished document ALINORM 97/31A; available from FAO or WHO).
	www.inchem.org /documents/jecfa/jecmono/v43jec02.htm (708 words)

Try your search on: Qwika (all wikis)