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Topic: Advanced Sleep Phase Syndrome

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	Sleep Disorders Glossary, Cincinnati Children's Hospital Medical Center
		Advanced Sleep Phase Syndrome (ASPS) occurs when a person's "body clock" (i.e., circadian rhythm) is set to fall asleep very early in the afternoon.
		Limit-setting sleep disorder is more common for children who are fully ambulatory and have developed receptive and expressive language skills (typically after age 2).
		Overnight sleep studies involve observing a child's sleep in a sleep laboratory in order to better understand problems that could be causing the sleep disorder.
	www.cincinnatichildrens.org /svc/alpha/s/sleep-disorders/glossary.htm?view=content (1870 words)

	Advanced Sleep Phase Syndrome
		Advanced sleep phase syndrome is a disorder in which the major sleep episode is advanced in relation to the desired clocktime, that results in symptoms of compelling evening sleepiness, an early sleep onset, and an awakening that is earlier than desired.
		Individuals with advanced sleep phase syndrome who attempt to work evening or night shifts would have difficulty staying awake during the evening and early morning hours.
		Advanced sleep phase syndrome is treated with chronotherapy or bright light therapy.
	www.stanford.edu /~dement/advanced.html (523 words)

	DeVilbiss - Sleep Glossary
		Sleep fragmentation connotes repetitive interruptions of sleep by arousal and awakenings.
		Sleep apnea is a breathing disorder characterized by brief interruptions of breathing during sleep.
		Sleep paralysis is due to an ill-timed disconnection between the brain and the body.
	www.sleepcompliance.com /html/glossary.htm (4718 words)

	Insomnia - Causes & Risk Factors - Sleepchannel.com
		Consequently, sleep, the one environment that soothes and rebuilds the body, is undermined by stress and anxiety.
		People who associate anxiety with their conventional sleep environment typically find it easier to sleep in unfamiliar environments, such as a hotel room, a friend’s house, or the couch, where sleep-preventive associations are absent.
		Inadequate sleep hygiene consists of all the habits that are not conducive to sleep longevity, like late-night exercise, late-night stressful activities (e.g., balancing the checkbook right before bedtime), late-night consumption of alcohol or caffeine, sleeping with loud noise, and sleeping on a poor mattress.
	www.sleepdisorderchannel.net /insomnia/causes.shtml (1285 words)

	Insomnia Treatments, Treatment For Sleep Disorder, Circadian Rhythm Disorder, Circadian Rhythm Sleep Disorder, Chronic ...
		Sleep deprivation and this misalignment of rhythms are two of the most important factors in decreased performance and increased accident rates associated with night work, and may also impact other health consequences of shift work (e.g., digestive and cardiovascular).
		An alternative approach to use, when the direction (either advancing or delaying rhythms) is important, requires bright light exposure aimed to one side or the other of the expected temperature minimum, and gradually moved closer on successive days so that it eventually would come close enough to produce the desired direction of phase shift.
		These children have a sleep disorder that is debilitating for them and for their families: they sleep in short 'snatches' throughout the day and night, with a complete lack of sleep consolidation.
	www.sunbox.com /Research/SCRD.asp (3158 words)

	Sleep disorder - Wikipedia, the free encyclopedia
		A sleep disorder (somnipathy) is a disorder in the sleep patterns of a person or animal.
		Sleep apnea: The obstruction of the airway during sleep
		William Dement, of the Stanford Sleep Center, anyone who snores and has daytime drowsiness should be evaluated for sleep disorders.
	en.wikipedia.org /wiki/Sleep_disorders (440 words)

	Advanced Sleep Phase Syndrome (Site not responding. Last check: 2007-10-21)
		During a night of sleep, a person usually has about four or five periods of REM sleep, which are quite short at the beginning of the night, but long at the end.
		With advances in portable electronics, patients are now sent home with a small electronic device that is strapped to a fingertip to measure the oxygen content of the blood.
		'''Insomnia''' is a form of sleep disorder characterised by an inability to sleep and/or to remain asleep for a reasonable period during the night.
	www.dreamweaverbeds.com /sleep-dictionary.htm (11125 words)

	Sleep terms Definitions
		Advanced Sleep Phase Syndrome (ASPS) - Phases of the daily sleep/wake cycle are advanced with respect to clock time. This is classified as a circadian rhythm disorder. The sleep phase occurs well ahead of the conventional bedtime and the tendency is to wake up too early.
		Dyssomnia - a disorder of sleep or wakefulness; not a parasomnia
		Phase advance - movement to a position earlier in the 24 hour sleep - wake cycle of a period of sleep or wake; for example, a shift of the sleep phase from 11 p.m.
	www.sleepnet.com /definition.html (6877 words)

	Light Therapy, Circadian Rhythms and Sleep Disorders by Sunnex Biotechnologies
		Sleep phase disorders occur when a person's internal biological clock is normally delayed or advanced from the external environment.
		People with an Advanced Sleep Phase Syndrome, who tend to be older, become tired in the late afternoon or early evening and wake in the early morning.
		People with delayed or advanced sleep phase syndromes would be well advised to consult with a qualified sleep therapist before embarking on a program of light therapy.
	www.sunnexbiotech.com /frames/biological.html (476 words)

	Mid-Michigan Sleep Center (Site not responding. Last check: 2007-10-21)
		Sleep is vital to a person’s health and well-being.
		Mid-Michigan Sleep Center is dedicated to providing an improvement to the quality of life for those who suffer from sleep disorders.
		The Sleep Center is devoted to the appropriate diagnosis, treatment and management of all types of sleep disorders.
	www.midmichigansleepcenter.com (253 words)

	Types of Insomnia \| From The Sleep Easily Directory at FoamSource.com (Site not responding. Last check: 2007-10-21)
		Delayed Sleep Phase Syndrome: This is when people have difficulty falling asleep at their regular bedtime, but can fall asleep more easily if they go to bed later than their regular bedtime...
		Advanced Sleep Phase Syndrome: This is when people feel the need to go to bed earlier than their regular bedtime....
		The result is a luxurious sleeping experience, not only because memory foam removes irksome pressure points that interfere with a restful sleep, but also because memory foam aims to relieve aches and pains that can accumulate throughout the working day.
	www.foamsource.com /sleepeasily/categories.php/8 (496 words)

	Sleep Wake Center
		Advanced Sleep Phase Syndrome is called a circadian rhythm condition because the daily rhythm of sleep and wake occur at an advanced (earlier) time of day.
		This type of sleep and activity pattern seems to be genetic in most cases and can be obvious to the parents even when their child is still quite young.
		Other sleep genes that are transmitted to offspring are known to cause FASPS in laboratory animals.
	uuhsc.utah.edu /sleepcenter/current.html (520 words)

	Circadian Rhythm Disorders, Sleep, THE MERCK MANUAL OF HEALTH & AGING
		Advanced sleep phase syndrome is a circadian rhythm disorder in which people fall asleep earlier in the evening and wake up earlier in the morning than they would like; it is common among older people.
		In delayed sleep phase syndrome, people fall asleep later at night and wake up later in the morning.
		Usually, the bright light is used in the evening for an advanced sleep phase and in the morning for a delayed sleep phase.
	www.merck.com /pubs/mmanual_ha/sec3/ch31/ch31g.html (426 words)

	ASPS of Aging
		Advanced Sleep Phase of Aging is a profound problem for the elderly population.
		In fact, one third of the population over 65 years of age experience a change in their sleep cycle when they fall asleep at earlier and earlier times and then wake up early in the morning.
		If your sleep patterns appear to match the sleep patterns currently under study, you may be asked to fill out additional questionnaires, submit additional information including medical records and/or test results and, in some cases, to come to the University of California, San Francisco for additional studies.
	www.ucsf.edu /humgene/asps_of_aging.htm (463 words)

	University of Miami School of Medicine - Glossary - Familial advanced sleep-phase syndrome (FASPS)
		Familial advanced sleep-phase syndrome (FASPS): An inherited abnormal sleep pattern in which the individual is a "morning lark" and consistently goes to sleep very early and is very early to rise.
		FASPS is inherited as a highly penetrant autosomal dominant trait, meaning males and females alike can have it and they run a 50-50 chance of passing it on to each of their children.
		The substitution results in a serine to glycine mutation Thus, a variant in human sleep behavior is due to a missense mutation in a clock component, hPER2, that alters the circadian period.
	www.med.miami.edu /glossary/art.asp?articlekey=15873 (233 words)

	Mid-Michigan Sleep Center - Sleep Disorders (Site not responding. Last check: 2007-10-21)
		The diagnosis of sleep apnea is usually made by an overnight sleep study done at a sleep disorder center.
		Is a sleep disorder of neurological origin, characterized by excessive daytime sleepiness.
		Is an overwhelming urge to move the legs usually caused by uncomfortable or unpleasant sensations in the legs.
	www.midmichigansleepcenter.com /sleep_disorders.html (412 words)

	Circadian rhythm sleep disorders caused by jet lag, shiftwork, delayed sleep phase syndrome, advanced sleep phase ...
		Circadian rhythm sleep disorders caused by jet lag, shiftwork, delayed sleep phase syndrome, advanced sleep phase syndrome
		Reason: it is easier to lengthen a circadian phase than to shorten it.
		This circadian rhythm disorder results in excessive sleepiness in the early evening with a resultant tendency to go to bed earlier (advancing the sleep time) and undesired awakening early in the morning.
	www.areyou-sleeping.com /JetLagandThenSome.html (916 words)

	Steve Parker - Articles/Others/Su-Laine (Site not responding. Last check: 2007-10-21)
		It is thought that DSPS is caused by an insufficient ability to reset the sleep/wake cycle in response to environmental time cues - perhaps the biological clocks of DSP individuals have an unusually long cycle, or perhaps they are not sensitive enough to time cues.
		There is an advanced sleep phase syndrome, which causes difficulty staying awake in the evening and staying asleep in the morning.
		Because DSPS was discovered only in 1981, and there is little awareness of the disorder, it is difficult to get a reliable estimate of how widespread DSPS is. About 7% of adolescents have DSPS, and it is probably responsible for 7 -10% of cases of chronic insomnia.
	steve-parker.org /articles/others/su-laine/circadian_abnormal.shtml (333 words)

	HHMI News: First Human Circadian Rhythm Gene Identified
		Researchers exploring the genetic basis of a rare syndrome that causes people to fall asleep and awaken earlier than normal have pinpointed the first human gene that controls circadian rhythm.
		"While advanced sleep-phase syndrome is common among the elderly—who tend to fall asleep and wake earlier as they age—a familial syndrome was not even identified until 1999," said Ptacek, who is at the University of Utah.
		According to Ptacek, individual members of the Utah family identified by Jones showed strong symptoms of a distinctive ASPS-type sleep pattern—as revealed by their answers to a questionnaire that covered sleep habits and time-preferences for activities such as test-taking and exercise.
	www.hhmi.org /news/ptacek2.html (1024 words)

	HHMI News: Researchers Discover Heritable Sleep Disorder
		Researchers studying three families with the same unusual sleep pattern have uncovered the first hereditary sleep disorder in humans caused by a single gene.
		Louis Ptácek, both at the University of Utah, are now searching for the gene that causes the disorder known as familial advanced sleep phase syndrome (FASPS).
		The most notable was a consistent advance of sleep onset and the first incidence of dream sleep by more than three hours.
	www.hhmi.org /news/ptacek.html (878 words)

	Sleep Review article (Site not responding. Last check: 2007-10-21)
		For some, the lifestyle that comes with this pattern is not troublesome, but for others, trying to fit their sleep style into a “regular” pattern is a cause of considerable stress and frustration.
		Once the sleep schedule has been changed to a more typical evening-to-bed, morning-to-rise schedule (often by advancing the to-bed time over several days), morning light therapy can be used to entrain the new schedule through morning melatonin suppression.
		It was not until more “advanced” times, particularly with more and more artificial light and artificial stimulation, that we as a species had to adapt to a later sleep-wake pattern.
	www.sleepreviewmag.com /Articles.ASP?articleid=S0405F03 (2047 words)

	Advanced Sleep Phase Syndrome (Site not responding. Last check: 2007-10-21)
		This syndrome is seen in the elderly and is characterized by excessive daytime sleepiness during the evening hours resulting in early bedtime.
		Sleep is otherwise normal in length and staging.
		It is due to an abnormally set circadian pacemaker.
	www-medlib.med.utah.edu /tommy2/glossary/gloss_asps.html (39 words)

	Disorders of the Sleep/Wake Cycle
		Circadian Rhythm Sleep Disorders are disorders that are related to the timing of sleep within the 24-hour day.
		Some of these disorders are influenced by the timing of the sleep period that is under the individual's control (e.g., shift work or time zone change).
		Sleep and Circadian Studies (SACS) -- The First Human study of human sleep in space.
	www.stanford.edu /~dement/circadian.html (458 words)

	Familial advanced sleep-phase syndrome: A short-period circadian rhythm variant in humans - Nature Medicine (Site not responding. Last check: 2007-10-21)
		The circadian rhythms of sleep, melatonin secretion and body core temperature are thought to be generated by the suprachiasmatic nucleus of the hypothalamus, the anatomic locus of the mammalian circadian clock
		Although a slight 'morning lark' tendency is common, individuals with a large and disabling sleep phase-advance are rare.
		This disorder, advanced sleep-phase syndrome, is characterized by very early sleep onset and offset; only two cases are reported in young adults
	www.nature.com /cgi-taf/DynaPage.taf?file=/nm/journal/v5/n9/abs/nm0999_1062.html&dynoptions=doi1106303513 (372 words)

	An hPer2 Phosphorylation Site Mutation in Familial Advanced Sleep-Phase Syndrome -- Data Supplement - Supplemental Data ... (Site not responding. Last check: 2007-10-21)
		We postulate that affected individuals in this branch of the family are phenocopies and that they represent examples of the difficulties inherent in mapping genes based on self-reported behavior.
		Inferring circadian phenotype from history alone (i.e., without measuring physiologic circadian phase markers in a controlled light-dark cycle or an endogenous period length in a time isolation facility) is difficult except in extreme cases.
		One of the four ASPS individuals in branch 3 was elderly and died early in the study before development of the most stringent criteria that ultimately evolved (1).
	www.sciencemag.org /cgi/content/full/1057499v1/DC1 (362 words)

	Sleep~Wake Center
		Central neurogenic hyperventilation: pharmacologic intervention with morphine sulfate and correlative analysis of respiratory, sleep, and ocular motor dysfunction.
		Familial advanced sleep-phase syndrome: a short period circadian rhythm variant in humans.
		Familial advanced sleep phase syndrome: an autosomal dominant circadian rhythm variant in humans.
	uuhsc.utah.edu /sleepcenter/published.html (259 words)

	Delayed Sleep Phase Syndrome
		As mentioned in the last article, Delayed Sleep Phase Syndrome (DSPS) is a subject of personal interest by one of our readers.
		She explained that her family is experiencing this disorder and it is disruptive to their lives.
		The “morning” person responds to this change by shortening their sleep time, and wakes up at their normal hour.
	www.suite101.com /article.cfm/9211/77164 (518 words)

	[No title] (Site not responding. Last check: 2007-10-21)
		extrinsic sleep disorders : ICSD - Extrinsic Sleep Disorders
		proposed sleep disorders : ICSD - Proposed Sleep Disorders
		sleep disorders associated with neurological disorders : ICSD - Sleep Disorders Associated with Neurological Disorders
	www.uni-marburg.de /sleep/enn/database/pub_stw.html (2492 words)

	Advanced Sleep Phase Syndrome : ASPS (Site not responding. Last check: 2007-10-21)
		Current city Street: Advanced Sleep Phase Syndrome : ASPS <
		Advanced Sleep Phase Syndrome (ASDS) is a sleep disorder in which patients feel very sleepy early in the evening (e.g.
		But it did not tremble, and her voice.html">voice.html">voice and France also--" She paused and looked toward the King, who was that was to make up for her husband's ungrateful indifference.
	www.city-search.org /as/asps.html (228 words)

	Sleep syndrome linked to genetic cause
		A genetic fault is the cause of sleep syndrome that disrupts the normal sleep-wake cycle.
		People with familial advanced sleep-phase syndrome go to bed around 8:30pm and wake at 5:30am.
		For some families early to bed early to rise is all in the genes.
	www.biomed.lib.umn.edu /hmed/1999/08/19990831_ss.html (120 words)

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