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Topic: Aging brain

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	Stem cell activity deciphered in the aging brain
		Previous studies by Shetty and others had demonstrated that as the brain ages, fewer new nerve cells, or neurons, are born in the hippocampus, the brain's learning and memory center.
		The common assumption had been that the brain drain was due to a decreasing supply of neural stem cells in the aging hippocampus, said lead study investigator Bharathi Hattiangady, Ph.D., research associate in neurosurgery.
		In the current study, however, the researchers found that the stem cells in aging brains are not reduced in number, but instead they divide less frequently, resulting in dramatic reductions in the addition of new neurons in the hippocampus.
	www.eurekalert.org /pub_releases/2006-12/dumc-sca121806.php (601 words)

	Brain Aging Journal
		Brain Aging International Journal (BAIJ) is an international journal published by the Ana Aslan International Academy of Aging, Bucharest, Romania.
		Thus, brain aging and the associated diseases are major public health problems in the modern world, the significance of which is estimated to grow markedly in the foreseeable future.
		Appropriately, research on brain aging has become the major area of neuroscience research and there is hardly a pharmaceutical company which is not working on developing therapeutic drugs to prevent, inhibit or reverse the loss of cognition associated with Alzheimer disease and other age-associated neurodegenerative conditions.
	www.brainaging.ro /Pub-BAJ.htm (766 words)

	Language in the Aging Brain Project
		Martin L. Albert, the Co-Founder and Co-Director of the Language in the Aging Brain Laboratory, is Professor of Neurology at Boston University School of Medicine and Director of the Harold Goodglass Aphasia Research Center at the VA Medical Center in Boston.
		Loraine Obler, the Co-Founder and Co-Director of the Language in the Aging Brain Laboratory, is Distinguished Professor of Speech and Hearing Sciences at City University of New York Graduate Center, and Research Associate in Psycholinguistics, Department of Neurology at Boston University School of Medicine.
		She is a linguist specializing in neurolinguistics with over 125 publications in her areas of expertise on such topics as the language changes of healthy aging and dementia, bilingualism, dyslexia, and cross-language studies of aphasia.
	www.bu.edu /lab/researchers.htm (827 words)

	Damaged genes in aging human brain provide clues to cognitive decline
		Unraveling the mysteries of the aging brain is a major goal for brain science, especially given the exploding population of senior citizens and the obvious desire to preserve brain function as long as possible.
		To investigate age-associated molecular changes in the human brain, Dr. Bruce A. Yankner, professor in the Department of Neurology and Division of Neuroscience at Children's Hospital Boston and Harvard Medical School, and colleagues examined patterns of gene expression in postmortem samples collected from thirty individuals ranging in age from 26 to 106 years.
		This is evidence that pathological events may be occurring in the aging brain, possibly related to gene damage.
	www.eurekalert.org /pub_releases/2004-06/chb-dgi060204.php (843 words)

	Aging Brain
		The indicator of an aging brain is loss of brain tissue with men losing brain tissue almost three times faster than women, according to a study conducted at the University of Pennsylvania in 1999.
		While the average age of an AD patient is in the 70s, the disease begins to make its appearance years earlier (in the 40s, 50s, or 60s) as mental problems such as chronic forgetfulness and difficulty in handling routine chores.
		Decrease of blood flow to the brain caused by hardening of the arteries is a significant contributing factor to dementia and memory loss.
	www.drlam.com /A3R_brief_in_doc_format/2001-No3-AgingBrain.cfm (3785 words)

	Harvard Gazette: Brain aging found to start at 40
		From ages 26 to 40 years, their brains show similar patterns of wear and tear and low levels of gene damage.
		Brain banking and the technology of studying the genes brains contain have evolved together and have now reached the point where evaluating the activity of thousands of genes can be done quickly.
		If the same fingerprint of aging can be detected in blood and skin cells, they might make possible simple tests to detect who is at greatest risk for Alzheimer's and other age-related conditions.
	www.news.harvard.edu /gazette/2004/06.17/03-brainaging.html (1033 words)

	FuturePundit: Brain Aging Archives
		Brain aging is going to be the hardest problem to solve because we will be able to grow replacements for most organs.
		First off, chronic back pain causes brain shrinkage that is equivalent to 10 to 20 years of brain aging.
		Loss in brain density is related to pain duration, indicating that 1.3 cubic centimeters of gray matter (the part of the brain that processes information and memory) are lost for every year of chronic pain, said lead researcher A.
	www.futurepundit.com /archives/cat_brain_aging.html (8727 words)

	Older but Mellower: Aging brain shifts gears to emotional advantage: Science News Online, June 24, 2006 (Site not responding. Last check: )
		As people age, from 12 to 79 years old, they respond to fear with greater and greater boosts in medial prefrontal activity (left) and to happiness with smaller and smaller boosts (right).
		Advancing age heralds a growth in emotional stability accompanied by a neural transition to increased control over negative emotions and greater accessibility of positive emotions, according to a team led by neuroscientist Leanne M. Williams of Westmead (Australia) Hospital.
		A brain area needed for conscious thought, the medial prefrontal cortex, primarily influences these emotional reactions in older adults, Williams and her colleagues say.
	www.sciencenews.org /articles/20060624/fob5.asp (776 words)

	The Aging Brain
		Until recently, brain aging-and everything that entails, from the annoying inconveniences of age-related memory loss to more serious conditions like Alzheimer's and dementia-was equated with neuron failure.
		More evidence that brain aging is related to chemical changes in the brain comes from studies that suggest an age-related loss of dopamine, the brain chemical associated with pleasure and reward, slows metabolism in the regions of the brain related to cognition.
		The research focuses on a particular set of brain cells deep in the brain known as cholinergic neurons, which are shown to deteriorate rapidly in those with Alzheimer's disease.
	www.usc.edu /hsc/info/pr/hmm/01spring/brain.html (2142 words)

	10 Must-Know Facts About Your Aging Brain -- ThirdAge
		Neuroplasticity, or brain plasticity, is the brain's ability to change physically --- creating new neural pathways and connections -- in response to new learning or stimuli.
		Brain plasticity is a powerful and natural force for driving beneficial changes in the brain.
		Although cognitive decline is a normal part of aging, a number of studies have shown that people who remain mentally active seem to experience less cognitive decline.
	www.thirdage.com /news/articles/ALT02/06/05/26/ALT02060526-01.html (531 words)

	Memory in the aging brain: Currents: UI Health Care
		Given the major implications of cognitive competency for personal independence and quality of life, together with growing evidence that how one lives in earlier stages of life affects cognitive aging, greater attention to memory and the aging brain is likely to have significant public health benefits.
		The relationship between normal aging and cognitive decline depends on many factors, and there is considerable variability in the extent of cognitive change experienced by different individuals as they age.
		As far as their influence on cognitive abilities in old age is concerned, these factors appear to be operative throughout the lifespan.
	www.uihealthcare.com /news/currents/vol4issue2/memoryagaing.html (1284 words)

	The Secret Life of the Brain : Episode 5
		At the age of 95, Stanley Kunitz was named poet laureate of the United States.
		The normal aging process leaves most mental functions intact, and may even provide the brain with unique advantages that form the basis for wisdom.
		The aging brain is also far more resilient than was previously believed.
	www.pbs.org /wnet/brain/episode5 (184 words)

	Aging Brain Changes Not Necessarily Alzheimer's
		Recent research by cognitive aging experts suggests that changes related to Alzheimer's disease appear in distinct regions of the brain and reflect unique pathology compared with changes that occur in older adults without dementia.
		For brain changes in non-demented aging, Buckner reviews studies that use structural magnetic resonance imaging (MRI) images to link white matter lesions in the anterior part of the brain with the severity of cognitive dysfunction.
		Together, these point toward a disrupted network in the brains of patients with Alzheimer's disease, which includes the medial temporal lobe and other regions of the brain that undergo atrophy and reduced glucose metabolism, and appear to be involved in memory impairment.
	www.seniorjournal.com /NEWS/Alzheimer's/4-10-01AgingBrain.htm (960 words)

	Neurological Research Confirms the Power of the Aging Brain
		Middle age is often referred to as a period of crisis, the beginning of a long downhill slide toward decrepitude and death.
		The Mature Mind, by Dr. Gene Cohen, director of the Center on Aging, Health and Humanities at George Washington University takes a positive view of aging, a process in which the brain is continually reshaped by lifelong learning and opportunities for growth.
		Cohen says the best news about the aging brain is that we all have control over its well-being, and that through simple, enjoyable activities we can nurture the extraordinary power of our mature minds.
	www.voanews.com /english/Science/2006-02-09-voa54.cfm (818 words)

	News: Saving the aging brain: Stimulation, exercise help to fight dementia - OCRegister.com
		The UCI Institute for Brain Aging and Dementia, Adult Day Services Orange County and the Alzheimer's Association of Orange County are hosting a two-day conference for medical professionals and people who provide care for the aged.
		Aging Americans can expect to live longer than ever before.
		And aging alone puts them at greater risk of dementia and Alzheimer's disease, which strike with greater frequency as people age.
	www.ocregister.com /ocregister/homepage/abox/article_1290374.php (1119 words)

	Aging Brain Reduces Ovulation
		This led Franke to conclude that the ageing of the brain reduces fertility.
		Ovulation of oocytes is one of the reproductive cycle factors that is regulated by the brain.
		Although the oestrogen concentrations in the blood had not changed with age, less receptors for oestrogen and progesterone were present in specific areas of the brain.
	www.sciencedaily.com /releases/2003/10/031013000659.htm (790 words)

	[No title]
		A new study has found that elderly men who took vitamin E and C supplements at least once a week over a number of years were protected from dementia and actually showed improvements in cognitive function -- a catch-all term including memory, creativity and mental acuity.
		The authors note that men who took both vitamin E and C supplements together for many years showed a substantially greater improvement, suggesting that long-term use is required to improve cognitive function in late life.
		The researchers believe that vitamin C and E may protect from brain damage because they are antioxidants and can mop up brain-damaging free radical particles.
	www.mercola.com /2000/apr/2/vitamin_c_e_senility.htm (418 words)

	Chicken Soup For The Aging Brain
		While Brain Age advertises that it can "train your brain in minutes a day," the Brain Fitness Program, marketed by Merzenich's Posit Science Corp., is a computer-based set of exercises that a user must sit down with an hour a day for eight weeks.
		PET scans of the brains of 15 participants were taken before and after the study.
		There was some evidence of memory gains in the Brain Fitness group, and the PET scans revealed a decline in brain activity in those who did not use the brain exercises.
	www.businessweek.com /magazine/content/06_39/b4002100.htm?chan=tc&chan=technology_technology+index+page_best+of+the+magazine (1342 words)

	Research Centre for Aging and the Brain - Baycrest
		Our Research Centre for Aging and the Brain includes the acclaimed Rotman Research Institute, considered one of the top five brain institutes in the world and the Kunin-Lunenfeld Applied Research Unit (KLARU) which conducts research alongside our clinicians and applies the results directly to client care.
		The primary research focus is on memory and the executive (frontal lobe) functions of the brain, both in normal aging and in the presence of diseases and conditions which affect the brain, such as stroke, traumatic brain injury, Alzheimer's disease and other dementias.
		The Research Centre for Aging and the Brain at Baycrest is looking for people to participate in memory and depression studies.
	www.baycrest.org /Research (339 words)

	Brain Aging/Cognitive
		Acetycholine is responsible for memory, Dopamine keeps your brain mentally alert and Serotonin keeps the brain focused.
		You can purchase these powerful brain boosting oils in convenient, easy to swallow capsules.
		Fish oil supplements contain oils from the flesh of cold water fish such as mackerel, salmon, fl cod, albacore tuna, sardines, and herring.
	www.lifeextensionvitamins.com /cogbrainag.html (524 words)

	Aging Brain Center
		Hebrew SeniorLife's Institute for Aging Research faculty focus on conditions that greatly impact adults as they age, and until their studies, had largely been ignored by the research community.
		In 2005 the Institute for Aging Research established the Aging Brain Center.
		The mission of the newly-established Aging Brain Center is to bring together investigators across disciplines in the greater Boston area and beyond to:
	www.instituteforagingresearch.org /home_institute.cfm?id=126&oTopID=126 (292 words)

	The Brain and Aging
		Brain changes such as these may not have any impact on memory and the changes vary widely from person to person.
		Although brain cells do die off, the process does not accelerate with age, and the areas of the brain that lose cells are not necessarily the ones that relate to memory.
		With aging, we often experience delayed recall — not being able to remember a familiar name or word — and it becomes harder to pay attention to more than one thing at a time.
	www.senioranswers.org /Pages/brainandaging.htm (738 words)

	The Brain & Aging - BioRap - brain damage
		Brain damage due to aging alone, as opposed to the diseases of aging, is minimal.
		Although the aging brain may lose 100,000 neurons a year, the brain seems to compensate for these losses.
		In one study, five hour long sessions in reasoning and memorizing skills were enough to help 40% of a group in their 70s regain lost mental functioning.
	www.biorap.org /rg/rgagebrainaging.html (112 words)

	Health-Effects of aging- Brain
		Research has shown that as brain ages or as people get older, there will be a decrease in brain weight and brain volume, widening of the grooves on the surface of the brain and enlargement of the ventricular system (ventricles- a cavity or hollow part of the brain).
		The decrease in brain weight and brain volume are probably due to loss of neurons (specialized cells transmitting nerve impulses) and extra cellular fluid.
		Man may have a 20% reduction in brain weight between the ages of forty -five and eighty -five and lose thirty to fifty thousand neurons a day from the brain and nervous system as they age.
	www.webindia123.com /health/age/brain/brain.htm (1083 words)

	THE MATURE MIND: The Power of the Aging Brain - Health - RedOrbit
		Cohen, acting director of the federal National Institute on Aging, sets out to correct what he sees as misrepresentations of the aging brain and to demonstrate that life after 60 can be a period of continued growth and development.
		He cites research indicating that that the brain, instead of being unchangeable, can form new neuron- to-neuron connections in response to new experiences.
		The author emphasizes that despite the increasing physical difficulties that accompany aging, this period of life can be marked by vigor and creativity.
	www.redorbit.com /news/health/389490/the_mature_mind_the_power_of_the_aging_brain/index.html?source=r_health (235 words)

	Aging Brain
		And problems with brain function are among the primary reasons individuals seek therapy or enter mental hospitals.
		Based on his brain imaging work with over 7,000 patients, Dr. Amen will teach you what specific parts of the brain do, and graphically show what happens when things go wrong, with case histories and illustrations of actual brain images.
		He will correlate different brain patterns with specific feelings and behaviors, such as moodiness, irritabiltiy, conflict avoidance, worrying, impulsivity, and temper outbursts, along with certain common psychiatric disorders such as depression, attention deficit disorder, anxiety, dementia, and substance abuse.
	www.ibh.com /html/aging_brain.html (386 words)

	\|\| DukeMedNews \|\| New Clues into the Aging Brain
		DURHAM, N.C. – Researchers have discovered a potential reason why learning and memory function declines with age: aging brains produce lower levels of critical growth factors that fuel the birth of new neurons in the hippocampus, the brain's learning and memory center, according to a study in rats.
		Scientists had previously speculated that newly born cells in the aging hippocampus were failing to reach their potential for one of three reasons: they were differentiating into mostly non-neuronal cells; they were not migrating to the proper brain regions; or they were failing to survive long enough.
		Shetty said his research is the first to examine long-term survival of newly born neurons in aging brains.
	www.dukemednews.org /news/article.php?id=9191 (822 words)

	The Human Brain - Exercise
		The human brain is able to continually adapt and rewire itself.
		And, reading-habits prior to age 18 are a key predictor of later cognitive function.
		Women at age 85 are known to be relatively free from cardiovascular disease, compared to men, and this relative absence of atherosclerosis is a likely biological explanation, according to Dr. A.
	sln.fi.edu /brain/exercise.htm (4758 words)

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