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Topic: Agmatine

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Arginine

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	PainOnline.com: Agmatine
		Argenine, a common amino acid, and agmatine are both found naturally in the body.
		Agmatine is found in small vesicles near the opposing surface of a nerve synapse.
		Agmatine is released through the influence of Calcium.
	www.painonline.com /mt-archives/2005/12/agmatine.html (548 words)

	Agmatine and Near-Death Experiences -- Neurotransmitter.net
		Agmatine, an endogenous neurotransmitter or neuromodulator, is an inhibitor of nitric oxide synthase and an antagonist of N-methyl-D-aspartate receptors.
		Agmatine reverses the NMDA-induced intracellular Ca(2+) overloading and the decrease of monoamines (including norepinephrine, epinephrine or dopamine) contents in PC12 cells, indicating that agmatine's antidepressant-like action may be related to its modulation of NMDA receptor activity and/or reversal of the decrease of monoamine contents and Ca(2+) overloading induced by NMDA." [Abstract]
		"Agmatine (decarboxylated l-arginine), an endogenous ligand of imidazoline and alpha(2) adrenoreceptors, is particularly enriched in the rat hypothalamic paraventricular (PVN) and supraoptic (SON) nuclei.
	www.neurotransmitter.net /neardeath.html (13492 words)

	Polyamine transport system mediates agmatine transport in mammalian cells -- Satriano et al. 281 (1): C329 -- AJP - ...
		Inhibition of mammalian nitric oxide synthases by agmatine, an endogenous polyamine formed by decarboxylation of arginine.
		Agmatine: an endogenous clonidine-displacing substance in the brain.
		Agmatine suppresses proliferation by frameshift induction of antizyme and attenuation of cellular polyamine levels.
	ajpcell.physiology.org /cgi/content/full/281/1/C329 (3092 words)

	Agmatine - Wikipedia, the free encyclopedia
		Agmatine inhibits nitric oxide synthase (NOS), and induces the release of some peptide hormones.
		The term "agmatine" was coined in 1910 by Albrecht Kossel, the German scientist who first identified the substance in herring sperm.
		Agmatine reduces infarct area in a mouse model of transient focal cerebral ischemia and protects cultured neurons from ischemia-like injury.
	en.wikipedia.org /wiki/Agmatine (171 words)

	Regulation of Ornithine Decarboxylase Activity and Polyamine Transport by Agmatine in Rat Pulmonary Artery Endothelial ...
		Agmatine, formed by the decarboxylation of arginine via the enzyme arginine decarboxylase, is widely and unevenly distributed
		Feng Y, Halaris AE and Piletz JE (1997) Determination of agmatine in brain and plasma using high-performance liquid chromatography with fluorescence detection [published erratum appears in J Chromatogr B Biomed Sci Appl (1997) 696:173].
		Reis DJ and Regunathan S (1999) Agmatine: An endogenous ligand at imidazoline receptors is a novel neurotransmitter.
	jpet.aspetjournals.org /cgi/content/full/296/2/372 (3759 words)

	Agmatine, a Bioactive Metabolite of Arginine . Production, Degradation, and Functional Effects in the Kidney of the Rat ...
		Agmatine is a biologically active substance, but the mode and sites of action have not been fully defined.
		Agmatine was infused at concentrations sufficient to establish ~ 6 µM, 0.8 µM and 0.1 µM concentrations in the urinary space.
		agmatine and is located in the kidney, primarily in glomeruli.
	www.jci.org /cgi/content/full/97/2/413 (5421 words)

	Regulation of Ornithine Decarboxylase Activity and Polyamine Transport by Agmatine in Rat Pulmonary Artery Endothelial ...
		Regulation of Ornithine Decarboxylase Activity and Polyamine Transport by Agmatine in Rat Pulmonary Artery Endothelial Cells -- Babál et al.
		Agmatine, a product of arginine decarboxylation in mammalian cells, is believed to govern cell polyamines by inducing antizyme,
		Agmatine Is Efficiently Transported by Non-Neuronal Monoamine Transporters Extraneuronal Monoamine Transporter (EMT) and Organic Cation Transporter 2 (OCT2)
	www.jpet.org /cgi/content/abstract/296/2/372 (493 words)

	Influence of cyclic AMP, agmatine, and a novel protein encoded by a flanking gene on speB (agmatine ureohydrolase) in ...
		Influence of cyclic AMP, agmatine, and a novel protein encoded by a flanking gene on speB (agmatine ureohydrolase) in Escherichia coli.
		The speB gene of Escherichia coli encodes agmatine ureohydrolase
		It is concluded that ORF1 encodes a protein which is a posttranscriptional
	jb.asm.org /cgi/lookup?vol=174&fp=758&view=abstract (280 words)

	The Effect of Agmatine Administration on Ischemic-Reperfused Isolated Rat Heart -- Greenberg et al. 6 (1): 37 -- ...
		The Effect of Agmatine Administration on Ischemic-Reperfused Isolated Rat Heart -- Greenberg et al.
		The Effect of Agmatine Administration on Ischemic-Reperfused Isolated Rat Heart
		S. REGUNATHAN and J. Regulation of Inducible Nitric Oxide Synthase and Agmatine Synthesis in Macrophages and Astrocytes
	cpt.sagepub.com /cgi/content/abstract/6/1/37 (384 words)

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