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Topic: Agnogenic myeloid metaplasia

	Agnogenic Myeloid Metaplasia - New Treatments, January 2, 2007
		Myelofibrosis in agnogenic myeloid metaplasia (AMM) is a secondary reaction to the clonal hemopathy.
		AMM occurs mainly in middle-age and elderly patients (median age at diagnosis is 60), and men and women are affected with equal frequency.
		AMM may be asymptomatic in as many as 25% of patients, and the diagnosis is made after investigation of abnormal blood findings or the discovery of splenomegaly.
	www.ccspublishing.com /journals4a/agnogenic_myeloid_metaplasia.htm (980 words)

	AR Online » Ultrasound » Case Reports » Agnogenic myeloid metaplasia presenting with omental implants ...
		The terms "myeloid metaplasia" and "extramedullary hematopoiesis" are used to describe a pathologic process of ectopic hematopoietic activity that may occur in any organ system but that primarily affects the liver and spleen.
		Myeloid metaplasia is not always associated with myelofibrosis, and either of these processes may occur in the absence of a clonal hematological disorder.
		Gastrointestinal and abdominal manifestations of agnogenic myeloid metaplasia.
	www.appliedradiology.com /case/case.asp?Id=190&IssueID=61&CatID=44&SubCatID=127&ThreadID=&Quiz= (933 words)

	Cell Communication and Signaling \| Full text \| TPO/Mpl Studies in Agnogenic Myeloid Metaplasia
		Agnogenic myeloid metaplasia (AMM) is one of the Philadelphia chromosome negative myeloproliferative disorder and is diagnosed by hyperplasia of atypical megakaryocytes, hepatosplenomegaly, extramedullary hematopoiesis and bone marrow fibrosis.
		Agnogenic myeloid metaplasia (AMM), polycythemia vera (PV), essential thrombocythemia (ET) and chronic myelogenous leukemia (CML) are characterized as myeloproliferative disorders (MPDs) arising due to exponential amplification of a haematopoietic stem cell.
		AMM, one of the Ph negative MPD is diagnosed by hyperplasia of atypical megakaryocytes, hepatosplenomegaly, extramedullary haematopoiesis and bone marrow fibrosis.
	www.biosignaling.com /content/3/1/4 (5720 words)

	Agnogenic myeloid metaplasia: cause, symptoms, treatment, how to prevent, long term outlook
		Agnogenic myeloid metaplasia is a condition that occurs when the bone marrow is scarred, making it less likely to manufacture blood cells.
		Agnogenic myeloid metaplasia leads to progressive bone marrow failure with severe anemia.
		Agnogenic myeloid metaplasia is also called, AMM, primary idiopathic myelofibrosis, and myelosclerosis.
	www.mamashealth.com /blood/ag.asp (213 words)

	TPO/Mpl Studies in Agnogenic Myeloid Metaplasia \| Cell Communication and Signaling, Volume 3 - Mirror @ Uni Potsdam
		Agnogenic myeloid metaplasia (AMM) is one of the Philadelphia chromosome negative myeloproliferative disorder and is diagnosed by hyperplasia of atypical megakaryocytes, hepatosplenomegaly, extramedullary hematopoiesis and bone marrow fibrosis.
		Agnogenic myeloid metaplasia (AMM), polycythemia vera (PV), essential thrombocythemia (ET) and chronic myelogenous leukemia (CML) are characterized as myeloproliferative disorders (MPDs) arising due to exponential amplification of a haematopoietic stem cell.
		AMM, one of the Ph negative MPD is diagnosed by hyperplasia of atypical megakaryocytes, hepatosplenomegaly, extramedullary haematopoiesis and bone marrow fibrosis.
	bmc.ub.uni-potsdam.de /1478-811X-3-4/text.htm (5680 words)

	UpToDate Treatment of chronic idiopathic myelofibrosis (primary myelofibrosis, agnogenic myeloid metaplasia)
		— Agnogenic myeloid metaplasia (AMM, called chronic idiopathic myelofibrosis (CIMF) in the WHO classification and primary myelofibrosis by the International Working Group on Myelofibrosis Research and Treatment), is one of the chronic myeloproliferative diseases.
		AMM, PPM, and PTM are all referred to as myelofibrosis with myeloid metaplasia (MMM).
		The primary disease process in AMM is a clonal hematopoietic stem cell disorder which results in chronic myeloproliferation and atypical megakaryocytic hyperplasia.
	patients.uptodate.com /topic.asp?file=leukemia/6366 (649 words)

	Agnogenic Myeloid Metaplasia (Site not responding. Last check: 2007-10-13)
		Agnogenic Myeloid Metaplasia Agnogenic myeloid metaplasia (AMM, primary idiopathic myelofibrosis, myelosclerosis) is a clonal stem cell defect characterized by panmyelosis, progressive bone marrow fibrosis and splenomegaly.
		There is an equal incidence of agnogenic myeloid metaplasia in males and females.
		Acute leukemia, usually myeloid type (AML), develops in 10-20% of patients with agnogenic myeloid metaplasia.
	www.mcl.tulane.edu /classware/pathology/Krause/AMM/AMM.html (260 words)

	Arch Intern Med -- Abstract: Spontaneous "remission' of agnogenic myeloid metaplasia and termination in acute myeloid ...
		Arch Intern Med -- Abstract: Spontaneous "remission' of agnogenic myeloid metaplasia and termination in acute myeloid leukemia, October 1, 1981, Ragni and Shreiner 141 (11): 1481
		Spontaneous "remission' of agnogenic myeloid metaplasia and termination in acute myeloid leukemia
		myeloid metaplasia 49 and 27 months, respectively, after initial diagnosis.
	archinte.ama-assn.org /cgi/content/abstract/141/11/1481 (100 words)

	eMedicine - Agnogenic Myeloid Metaplasia With Myelofibrosis : Article by Asheesh Lal, MBBS
		AMM is categorized as a chronic myeloproliferative disorder, along with chronic myelogenous leukemia (CML), polycythemia vera, and essential thrombocytosis.
		Extramedullary hematopoiesis in the spleen in a patient with agnogenic myeloid metaplasia.
		Jacobson RJ, Salo A, Fialkow PJ: Agnogenic myeloid metaplasia: a clonal proliferation of hematopoietic stem cells with secondary myelofibrosis.
	www.emedicine.com /med/topic78.htm (5200 words)

	MedNets : A medical search engine and health portal
		Agnogenic myeloid metaplasia is characterized by splenomegaly, immature peripheral blood granulocytes and erythrocytes, and teardrop-shaped red cells.
		As distinguished from chronic myelogenous leukemia, agnogenic myeloid metaplasia usually presents with a white blood cell count less than 30, 000 per cubic millimeter, prominent teardrops on peripheral smear, normocellular or hypocellular marrow with moderate to marked fibrosis, and an absence of the Philadelphia (Ph') chromosome.
		Untreated agnogenic myeloid metaplasia means that a patient is newly diagnosed and has had no prior treatment except supportive care.
	www.mednets.com /index.cfm/fuseaction/articles_myeloproliferative_disorders_myeloproliferative/articles_myeloproliferative_disorders_myeloproliferative_remove_highlighting.htm (979 words)

	Medical Dictionary: Agnogenic myeloid metaplasia - WrongDiagnosis.com
		Agnogenic myeloid metaplasia: A partial or complete replacement of the bone marrow stroma by fibrous tissue.
		Agnogenic myeloid metaplasia is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH).
		This means that Agnogenic myeloid metaplasia, or a subtype of Agnogenic myeloid metaplasia, affects less than 200,000 people in the US population.
	www.wrongdiagnosis.com /medical/agnogenic_myeloid_metaplasia.htm (342 words)

	Agnogenic Myeloid Metaplasia (Site not responding. Last check: 2007-10-13)
		This disease is marked by an enlarged spleen and progressive anemia.
		Also called chronic idiopathic myelofibrosis, primary myelofibrosis, myelosclerosis with myeloid metaplasia, and idiopathic myelofibrosis.
		Healthboard.com is a purely informational website, and should not be used as a substitute for professional legal, medical or technical advice.
	www.healthboard.com /Encyclopedia/term/agnogenic_myeloid_metaplasia.html (79 words)

	Publications List for Researcher (Site not responding. Last check: 2007-10-13)
		Bone marrow angiogenesis and its clinical correlates in myelofibrosis with myeloid metaplasia.
		Clinical correlates of splenic histopathology and splenic karyotype in myelofibrosis with myeloid metaplasia.
		Splenectomy in chronic myeloid leukemia and myelofibrosis with myeloid metaplasia.
	mayoresearch.mayo.edu /mayo/research/staff/publications-listed.cfm?personid=11248190 (1355 words)

	Definition of agnogenic myeloid metaplasia (Site not responding. Last check: 2007-10-13)
		agnogenic myeloid metaplasia -- A progressive, chronic disease in which the bone marrow is replaced by fibrous tissue and blood is made in organs such as the liver and the spleen, instead of in the bone marrow.
		This disease is marked by an enlarged spleen and progressive anemia.
		Also called chronic idiopathic myelofibrosis, primary myelofibrosis, myelosclerosis with myeloid metaplasia, and idiopathic myelofibrosis.
	www.teachmefinance.com /Scientific_Terms/agnogenic_myeloid_metaplasia.html (100 words)

	Myeloproliferative disorders: 101983 (Site not responding. Last check: 2007-10-13)
		The myeloproliferative disorders consist of polycythemia vera, chronic myelogenous leukemia, agnogenic myeloid metaplasia, and essential thrombocythemia.
		As distinguished from chronic myelogenous leukemia, agnogenic myeloid metaplasia usually presents with a white blood cell count less than 30,000 per cubic millimeter, prominent teardrops on peripheral smear, normocellular or hypocellular marrow with moderate to marked fibrosis, and an absence of the Philadelphia (Ph') chromosome or the bcr-abl translocation.
		In addition to the clonal proliferation of a multipotent hematopoietic progenitor cell, an event common to all chronic myeloproliferative disorders, myeloid metaplasia is characterized by colonization of extramedullary sites (such as the spleen or liver).
	www.acor.org /cnet/101983.html (1668 words)

	Myeloproliferative Diseases Information on Healthline
		The myeloproliferative diseases are four conditions- essential thrombocythemia, polycythemia vera, chronic myelocytic leukemia, and agnogenic myeloid metaplasia- characterized by overproduction of normal-looking blood cells.
		Agnogenic myeloid metaplasia (idiopathic myelofibrosis, myelofibrosis with myeloid metaplasia) begins like other myeloproliferative diseases, with overproduction of blood cells.
		Essential thrombocytopenia, polycythemia vera, and agnogenic myeloid metaplasia are usually diagnosed late in life, at an average (median) age of 60.
	www.healthline.com /galecontent/myeloproliferative-diseases (1088 words)

	IngentaConnect Agnogenic myeloid metaplasia with pulmonary hematopoiesis (Site not responding. Last check: 2007-10-13)
		Agnogenic myeloid metaplasia (AMM) is characterized by bone marrow fibrosis, splenomegaly and leukoerythroblastic anemia and is frequently accompanied by extramedullary hematopoiesis (EMH).
		We report the case of a 77-year-old man with agnogenic myeloid metaplasia (AMM) treated with hydroxyurea, who seven years after diagnosis presented with dyspnea and severe hypoxemia.
		Pulmonary EMH is rare in patients with AMM, but should be considered in patients with hypoxemia and respiratory distress.
	www.ingentaconnect.com /content/tandf/ghem/2005/00000010/00000006/art00009 (177 words)

	Thalidomide Effective for Myelofibrosis with Myeloid Metaplasia (Site not responding. Last check: 2007-10-13)
		In one study from the Mayo Clinic, 21 patients with myeloid metaplasia and myelofibrosis were treated with 50 mg per day of thalidomide and a 3 month course of oral prednisone at a dose of 0.5 mg per kg per day.
		Low-Dose Thalidomide Ameliorates Cytopenias and Splenomegaly in Myelofibrosis with Myeloid Metaplasia: A Phase II Trial.
		Myeloablation and autologous peripheral blood stem cell rescue results in hematologic and clinical responses in patients with myeloid metaplasia with myelofibrosis.
	www.cancerconsultants.com /syndication/veContent.jsp?ArticleID=leukemia_feb04m&ArticleTypeID=PRON (511 words)

	Stanford Cancer Center - Agnogenic Myeloid Metaplasia (AMM) \| Cancer Types \| Stanford Cancer Center (Site not responding. Last check: 2007-10-13)
		Agnogenic myeloid metaplasia (AMM), also known as chronic idiopathic myelofibrosis, is a form of cancer that arises in the bone marrow.
		AMM symptoms are somewhat similar to chronic myelogenous leukemia (CML) but patient lack the genetic defect known to cause CML.
		Yet because AMM is rare it can be difficult to find a doctor who has treated patients with the disease.
	cancer.stanfordhospital.com /OldSite/cancerTypes/leukemias/agnogenicMyeloidMetaplasia (345 words)

	Agnogenic myeloid metaplasia with extramedullary hematopoiesis and fibrosis in the lung. Report of two cases -- Asakura ...
		Agnogenic myeloid metaplasia with extramedullary hematopoiesis and fibrosis in the lung.
		Agnogenic myeloid metaplasia (AMM) is a chronic hematologic disorder with a
		AMM and EMH involving the lung and pleura is reviewed.
	www.chestjournal.org /cgi/content/abstract/105/6/1866 (180 words)

	Mayo Clinic: Myelofibrosis with Myeloid Metaplasia - Information and treatment options at mayoclinic.org
		Mayo Clinic is a world leader in treating patients with myelofibrosis with myeloid metaplasia (myelofibrosis).
		Myelofibrosis with myeloid metaplasia is a chronic form of leukemia.
		The disease, also known as agnogenic myeloid metaplasia, may arise by itself or evolve from other myeloproliferative diseases (diseases that cause overproduction of blood cells in the bone marrow) such as essential thrombocythemia or polycythemia vera.
	www.mayoclinic.org /myelofibrosis (341 words)

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		Agnogenic Myeloid Metaplasia Murray N Silverstein Textbooks and...
		Agnogenic myeloid metaplasia presenting with omental implants and ascites.
		Prognostic factors in agnogenic myeloid metaplasia: a report on...
	health.cancer-help.org /include/files/Agnogenic_Myeloid_Metaplasia.txt (351 words)

	Detection of Aberrant Gene Expression in CD34+ Hematopoietic Stem Cells from Patients with Agnogenic Myeloid Metaplasia ...
		Agnogenic myeloid metaplasia (AMM) is a clonal stem cell disorder
		Evaluation and clinical correlations of microvessel density in myelofibrosis with myeloid metaplasia.
		Population-based incidence and survival figures in essential thrombocythemia and agnogenic myeloid metaplasia: an Olmsted County study, 1976–1995.
	stemcells.alphamedpress.org /cgi/content/full/23/5/631 (3524 words)

	AllRefer Health - Primary Myelofibrosis (Agnogenic Myeloid Metaplasia, Idiopathic Myelofibrosis, Myelofibrosis, Myeloid ...
		AllRefer Health - Primary Myelofibrosis (Agnogenic Myeloid Metaplasia, Idiopathic Myelofibrosis, Myelofibrosis, Myeloid Metaplasia)
		Alternate Names : Agnogenic Myeloid Metaplasia, Idiopathic Myelofibrosis, Myelofibrosis, Myeloid Metaplasia
		Primary myelofibrosis is a disorder of the bone marrow in which the marrow is replaced by fibrous (scar) tissue.
	health.allrefer.com /health/primary-myelofibrosis-info.html (345 words)

	Arch Intern Med -- Abstract: Splenectomy in agnogenic myeloid metaplasia and postpolycythemic myeloid metaplasia. A ...
		Arch Intern Med -- Abstract: Splenectomy in agnogenic myeloid metaplasia and postpolycythemic myeloid metaplasia.
		Splenectomy in agnogenic myeloid metaplasia and postpolycythemic myeloid metaplasia.
		myeloid metaplasia (AMM) and 12 patients with postpolycythemic myeloid
	archinte.ama-assn.org /cgi/content/abstract/148/11/2501 (209 words)

	Idiopathic myelofibrosis (agnogenic myeloid metaplasia) in a marmoset (Callithrix jacchus): hematologic and ...
		Idiopathic myelofibrosis (agnogenic myeloid metaplasia) in a marmoset (Callithrix jacchus): hematologic and histopathologic changes -- Khan et al.
		Idiopathic myelofibrosis (agnogenic myeloid metaplasia) in a marmoset (Callithrix jacchus): hematologic and histopathologic changes
		Idiopathic myelofibrosis (IMF), or agnogenic myeloid metaplasia, was
	www.vetpathology.org /cgi/content/abstract/34/4/341 (150 words)

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