| | eMedicine - Venous Air Embolism : Article Excerpt by: Andrew G Wittenberg, MD, MPH (Site not responding. Last check: 2007-10-11) |
 | | The factors that determine the subsequent morbidity and mortality in VAE include the rate of air entrainment, the volume of air introduced, and the position of the patient at the time of the embolism. |
 | | Intermediate amounts of air collect in the pulmonary circulation and produce a pulmonary vascular injury manifested by precapillary and postcapillary pulmonary vasoconstriction, pulmonary hypertension, endothelial injury, and permeability pulmonary edema. |
 | | Although classical teaching states that more than 5 mL/kg of air (IV) is required for significant injury (including shock and cardiac arrest), patient complications secondary to as little as 20 mL of air (the length of an unprimed IV infusion set) have been reported. |
| www.emedicine.com /emerg/byname/venous-air-embolism.htm (715 words) |