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Topic: Aldosterone

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List of biomedical topics, A to E

	MedlinePlus Medical Encyclopedia: Aldosterone
		Aldosterone is a hormone released by the adrenal glands.
		Aldosterone is the main sodium-retaining hormone from the adrenal gland.
		Frequently, blood aldosterone levels are combined with other blood tests (plasma renin activity) or provocative tests (captopril test, intravenous saline infusion test or ACTH infusion test) in order to diagnosis over- or under-production of the hormone.
	www.nlm.nih.gov /medlineplus/ency/article/003704.htm (534 words)

	Endotext.com - Adrenal Physiology And Diseases, Aldosterone Excess
		Abnormal overproduction of aldosterone, due to either primary or secondary disorders, is prevalent in the general population, and is an important cause of morbidity and mortality.
		Glucocorticoid-remediable aldosteronism (also known as familial hyperaldosteronism type I) is an autosomal dominant disorder characterized by a chimeric duplication whereby the 5’-promotor region of the 11 B-hydroxylase gene (regulated by ACTH) is fused to the coding sequences of the aldosterone synthase gene (29).
		Aldosterone excretion greater than 39 nmol/d (14 ug/d), in the presence of a urinary sodium excretion greater than 200 mmol per 24 hour, is 96% sensitive and 93% specific for the diagnosis of primary hyperaldosteronism.
	www.endotext.org /adrenal/adrenal23/adrenal23.htm (5199 words)

	Aldosterone assay
		Aldosterone measurement is useful in detecting a condition called aldosteronism, which is caused by excess secretion of the hormone from the adrenal glands.
		Secondary aldosteronism is more common and may occur with congestive heart failure, cirrhosis with fluid in the abdominal cavity (ascites), certain kidney diseases, excess potassium, sodium-depleted diet, and toxemia of pregnancy.
		Increased levels of aldosterone are found in Conn's disease (aldosterone-producing adrenal tumor), and in cases of Bartter's syndrome (a condition in which the kidneys overexcrete potassium, sodium and chloride, resulting in low blood levels of potassium and high blood levels of aldosterone and renin).
	www.lifesteps.com /gm/Atoz/ency/aldosterone_assay_pr.jsp (750 words)

	Aldosterone - [Medical Test] (Site not responding. Last check: )
		An aldosterone test is done to measure the level of the hormone aldosterone in the blood, which is produced by the adrenal glands.
		Aldosterone helps regulate levels of sodium and potassium in the body, which in turn helps control blood pressure, the distribution of fluids in the body, and the balance of electrolytes in the blood.
		Aldosterone levels may vary between men and women and are somewhat dependent on the amount of salt in a person's diet.
	www.bcbswny.com /kbase/topic/medtest/hw6534/descrip.htm (284 words)

	Aldosterone - Health Centers
		Aldosterone is a hormone released by the adrenal glands.
		Aldosterone is the main sodium-retaining hormone from the adrenal gland.
		Frequently, blood aldosterone levels are combined with other blood tests (plasma renin activity) or provocative tests (captopril test, intravenous saline infusion test or ACTH infusion test) in order to diagnosis over- or under-production of the hormone.
	www.channel3000.com /encyclopedia/6864771/detail.html (647 words)

	Aldosterone - Health Encyclopedia
		Aldosterone is a hormone released by the adrenal glands.
		Aldosterone is the main sodium-retaining hormone from the adrenal gland.
		Frequently, blood aldosterone levels are combined with other blood tests (plasma renin activity) or provocative tests (captopril test, intravenous saline infusion test or ACTH infusion test) in order to diagnosis over- or under-production of the hormone.
	www.nbc4.tv /encyclopedia/6864771/detail.html (682 words)

	Aldosterone
		An aldosterone test measures the level of aldosterone (a hormone made by the adrenal glands), in the blood.
		The kidney hormone renin normally stimulates the adrenal glands to release aldosterone.
		High levels of both renin and aldosterone are normally present when the body is trying to conserve fluid and salt (sodium).
	www.webmd.com /a-to-z-guides/aldosterone (387 words)

	CIGNA - Aldosterone in Urine (Site not responding. Last check: )
		An aldosterone test measures the level of aldosterone (a hormone made by the adrenal glands), in the urine.
		Symptoms of a high aldosterone include high blood pressure, muscle cramps and weakness, numbness or tingling in the hands, and low levels of potassium in the blood.
		Aldosterone levels may be high in the third trimester of pregnancy.
	www.cigna.com /healthinfo/tw12850.html (815 words)

	Hypertension Online Slides - aldosterone, ARB, angiotensin receptor blocker
		The potent mineralocorticoid, aldosterone, is produced by the adrenal zona glomerulosa in response to angiotensin II stimulation.
		Aldosterone has been implicated in vascular, myocardial and renal fibrosis that occurs in patients with arteriosclerosis, congestive heart failure and renal failure, particularly if hypertension is also present and is accompanied by activation of the RAAS.
		The mechanisms by which aldosterone contributes to vascular and renal fibrosis is not well understood, but there are several experimental findings that support the mechanisms included in the illustration.
	www.hypertensiononline.org /slides2/slide01.cfm?q=aldosterone (271 words)

	Aldosterone hormone : by Ray Sahelian, M.D. Effects of Aldosterone hormone aldosterone function
		In patients with mild to moderate hypertension the prevalence of primary aldosteronism is 5% to 10%, whereas in subjects with resistant hypertension the prevalence is approximately 20%.
		The benefits of aldosterone receptor antagonists (spironolactone and eplerenone) for patients with heart failure were shown in 2 recent randomized controlled trials.
		Some of the proposed mechanisms of action of aldosterone antagonists are (1) inhibition of myocardial and vascular remodeling, (2) blood pressure reduction, (3) decreased collagen deposition, (4) decreased myocardial stiffness, (5) prevention of hypokalemia and arrhythmia, (6) modulation of nitric oxide synthesis, and (7) immunomodulation.
	www.raysahelian.com /aldosterone.html (630 words)

	Aldosterone - The Future Challenge in Cardiovascular Disease? (Site not responding. Last check: )
		Aldosterone is principally (but not exclusively) synthesised in the zona glomerulosa of the adrenal cortex, and is normally released in response to angiotensin II and potassium (figure 1).
		Aldosterone antagonism is now of proven benefit in heart failure, with highly significant reductions in morbidity and mortality with spironolactone in patients with advanced coronary heart failure and, more recently, with eplerenone in the acute setting.
		Aldosterone: a mediator of myocardial necrosis and renal arteriopathy.
	www.arabmedmag.com /issue-15-10-2005/cardiology/main04.htm (4663 words)

	Endotext.com - Adrenal Physiology And Diseases, Aldosterone Deficiency and Resistance (Site not responding. Last check: )
		Aldosterone is crucial for sodium conservation in the kidney, salivary glands, sweat glands and colon.
		Aldosterone and the MR may be involved in the regulation of genes coding for the subunits of the amiloride sensitive sodium channel and the Na-K ATP ase pump, as well as of other proteins (22,23).
		Interestingly, the same patient was unresponsive to intravenous infusion of aldosterone and fludrocortisone (up to 3 mg/day) when studied in infancy (108), suggesting that the clinical improvement that has been noted in the majority of PHA patients with age may be related to changes in their responsiveness to mineralocorticoid.
	www.endotext.org /adrenal/adrenal24/adrenal24.htm (5550 words)

	Aldosterone and Renin: The Test
		Primary hyperaldosteronism is caused by the overproduction of aldosterone by the adrenal glands, usually by a benign tumor of one of the glands.
		Since primary aldosteronism is a potentially curable cause of hypertension, and because it is often resistant to conventional treatment for high blood pressure, some doctors order aldosterone and renin levels when they want to help clarify the treatments that are likely to be effective in patients with high blood pressure.
		Aldosterone levels fall to very low levels with severe illness, so testing should not be done at times when a person is very ill. Stress and strenuous exercise can temporarily increase aldosterone results.
	www.labtestsonline.org /understanding/analytes/aldosterone/test.html (764 words)

	aldosterone - HighBeam Encyclopedia
		Aldosterone acts directly on the kidney to decrease the rate of sodium-ion excretion (with accompanying retention of water), and to increase the rate of potassium-ion excretion.
		First, the concentration of sodium ions may be a factor since increased rates of aldosterone secretion are found when dietary sodium is severely limited.
		Aldosterone excretion among subjects with resistant hypertension and symptoms of sleep apnea *.(clinical investigations)
	www.encyclopedia.com /doc/1E1-aldoster.html (620 words)

	Aldosterone ELISA Kit, Cat # 1875,
		Aldosterone is a potent mineral corticoid whose synthesis and release are controlled by the renin-angiotensin system of the body.
		Aldosterone promotes the re-absorption of sodium in the distal tubules of the kidney resulting in potassium secretion along with sodium retention, which controls the circulating blood volume.
		Measurement of aldosterone levels in serum in conjunction with plasma renin levels can be used to differentiate between primary and secondary aldosteronism.
	www.4adi.com /kits/hormones/1875ald.html (496 words)

	UpToDate Chapter 6C: Aldosterone
		The major adrenal hormones are synthesized in different areas of the adrenal cortex: aldosterone in the zona glomerulosa, and glucocorticoids (particularly cortisol), androgens, and estrogens in the zona fasciculata and reticularis.
		Aldosterone synthase has over 95 percent homology with 11ß-hydroxylase (which converts deoxycortisol to cortisol in the zona fasciculata) and their genes are located in the same region on chromosome 8 [5].
		Aldosterone increases the abundance of the alpha subunit and promotes the phosphorylation of the beta and gamma subunits of the luminal membrane Na+ channel through which luminal Na+ enters the cells [12,13].
	patients.uptodate.com /topic.asp?file=ren_phys/8433 (555 words)

	Aldosterone in Blood
		An aldosterone test measures the level of aldosterone (a hormone made by the adrenal glands), in the blood.
		Aldosterone levels in a blood sample also change depending on whether you are standing up or lying down at the time the blood is taken.
		Aldosterone levels may be high in the third trimester of pregnancy.
	www.meritcare.com /hwdb/showtopic.aspx?module_abbrev=MEDICALTEST&pd_hwid=hw6534&print=yes (1111 words)

	Aldosterone assay
		Aldosterone measurement is useful in detecting a condition called aldosteronism, which is caused by excess secretion of the hormone from the adrenal glands.
		Secondary aldosteronism is more common and may occur with congestive heart failure, cirrhosis with fluid in the abdominal cavity (ascites), certain kidney diseases, excess potassium, sodium-depleted diet, and toxemia of pregnancy.
		Increased levels of aldosterone are found in Conn's disease (aldosterone-producing adrenal tumor), and in cases of Bartter's syndrome (a condition in which the kidneys overexcrete potassium, sodium and chloride, resulting in low blood levels of potassium and high blood levels of aldosterone and renin).
	www.healthatoz.com /healthatoz/Atoz/ency/aldosterone_assay.jsp (681 words)

	AllRefer Health - 24-Hour Urinary Aldosterone Excretion Rate (Aldosterone - Urine) - Test/Medical Exams/Tests
		A test that measures the amount of aldosterone eliminated in the urine in a day (see the blood aldosterone test).
		The test evaluates the excretion of aldosterone in the urine.
		Aldosterone is a hormone secreted by the adrenal gland which acts on the kidney to regulate salt and potassium balance.
	health.allrefer.com /health/24-hours-urinary-aldosterone-excretion-rate-info.html (423 words)

	Aldosterone in Blood - [Medical Test] - Quest Diagnostics Patient Health Library (Site not responding. Last check: )
		An aldosterone test is often done at the time of a routine blood test.
		The amount of aldosterone in blood changes depending on whether you are standing up or lying down.
		Your doctor may ask you to have your blood drawn at a certain time because aldosterone levels are highest in the early morning.
	www.questdiagnostics.com /kbase/topic/medtest/hw6534/how2prep.htm (324 words)

	Hormone aldosterone is promising target for stroke treatment
		She is among an increasing number of scientists who think the hormone, aldosterone, is part of the problem and blocking it may be part of the solution.
		She calls aldosterone "a double-edged sword" that helps maintain healthy blood pressure but also dangerously reshapes blood vessels and makes the heart fibrotic.
		However the potential for aldosterone blockers may still be unfolding as researchers such as Dr. Dorrance discover what the hormone does and what blocking it prevents.
	www.eurekalert.org /pub_releases/2005-11/mcog-hai113005.php (944 words)

	CIGNA - Aldosterone in Blood (Site not responding. Last check: )
		An aldosterone test measures the level of aldosterone (a hormone made by the adrenal glands), in the blood.
		Aldosterone levels in a blood sample also change depending on whether you are standing up or lying down at the time the blood is taken.
		An overgrowth of normal cells in the adrenal glands (called adrenal hyperplasia) or a tumor of the adrenal glands affects the adrenal glands directly and cause a condition called primary aldosteronism.
	www.cigna.com /healthinfo/hw6534.html (1099 words)

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