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Topic: Alfred Hershey


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DNA

In the News (Sun 27 May 12)

  
  CSHL - History: Alfred Hershey
Al Hershey was working on a little-studied organism called bacteriophage with phage researcher J.J. Bronfenbrenner at Washington University in St. Louis when he received a letter from the brash and brilliant German scientist at Vanderbilt University, Max Delbruck.
Hershey went, and thus formed the third point in the nucleus of the nascent American phage group.
Hershey allowed this to occur, but then at the crucial moment he whirred them in a Waring Blendor, which he had discovered produced just the right shearing force to tear the phage particles from the bacterial walls but not rupturing the bacteria.
www.cshl.edu /History/hershey.html   (418 words)

  
 Alfred Hershey - MSN Encarta
Alfred Hershey (1908-1997), American geneticist and winner of the 1969 Nobel Prize in physiology or medicine, which he shared with Italian-born American microbiologist Salvador Edward Luria and German-born American biologist Max Ludwig Henning Delbrück for their discoveries concerning the replication mechanism of viruses and their genetic structure.
Six years later, in 1952, Hershey and American geneticist Martha Chase conducted their famous “blender experiment” in which, using a Waring blender, they separated the protein coating of the bacteriophage from its nucleic acid core.
Hershey's work contributed directly to this discovery, and also to the development of vaccines against polio, measles, and mumps.
encarta.msn.com /encyclopedia_761582567/Alfred_Hershey.html   (447 words)

  
 Dr. Alfred Day Hershey
Hershey became a geneticist and in 1969 was the recipient of a Nobel Prize for Medicine and Physiology for the discovery concerning the replication mechanism and the genetic structure of viruses.
Hershey is Recipient of the Kimber Genetics Award of the National Academy of Sciences, 1965.
Hershey was working on a little-studied organism called bacteriophage with phage researcher J.J. Bronfenbrenner at Washington University in St. Louis when he received a letter from a German scientist at Vanderbilt University, Max Delbruck.
www.shiawasseehistory.com /hershey.html   (635 words)

  
 Alfred Day Hershey
Alfred Hershey, the American geneticist, was born December 4, 1908 in Owosso, Michigan.
Hershey was promoted to instructor in 1936, assistant professor in 1938 and associate professor in 1942.
Hershey was awarded the 1969 Nobel Prize in physiology or medicine, along with Luria and Delbruck, for their discovery on the replication of viruses and their genetic structure.
library.thinkquest.org /20465/hershey.html   (361 words)

  
 Alfred Day Hershey, pioneer in DNA research   (Site not responding. Last check: )
Alfred Day Hershey, Ph.D., a Nobel laureate who spent the first 16 years of his career at the School of Medicine, died Thursday, May 22, 1997, at his home in Syosset, N.Y. He was 88.
Hershey moved to the Genetics Research Unit of the Carnegie Institution at Cold Spring Harbor Laboratory in New York in 1950.
Hershey shared the 1969 Nobel Prize for physiology or medicine with Max Delbrück and Salvador Luria for "discoveries concerning the replication mechanism and the genetic structure of viruses." At the ceremony, it was noted that the three scientists must "be regarded as the original founders of the modern science of molecular biology."
record.wustl.edu /archive/1997/06-12-97/7938.html   (403 words)

  
 Alfred Hershey Summary
The task before Hershey was to show that it was the phage DNA that was passed on to succeeding generations and that gave the signal for replication and growth.
Hershey was "known to his colleagues as a very quiet, withdrawn sort of man who avoids crowds and noise and most hectic social activities," according to the report of the 1969 Nobel Prize in the October 17, 1969, New York Times.
Hershey was "known to his colleagues as a quiet man who avoids crowds and noise and most hectic social activities," according to the report of the 1969 Nobel Prize in the 17 October 1969 New York Times.
www.bookrags.com /Alfred_Hershey   (3866 words)

  
 HERSHEY, Alfred Day
Further research helped him demonstrate the process responsible for the genetic exchange between two virus particles simultaneously infecting the same bacterial cell as well as for the combination of parts of their strings of genes to form new types of viruses.
Hershey shared the 1969 Nobel Prize in physiology or medicine with Delbrück and Luria for their “discoveries concerning the replication mechanism and the genetic structure of viruses.”
Alfred Hitchcock, the macabre master of moviemaking, is born in London on August 13, 1899.
www.history.com /encyclopedia.do?articleId=211828   (632 words)

  
 Hershey, Alfred Day (1908-1997): World of Microbiology and Immunology
By seeking to understand the reproduction of viruses, Alfred Day Hershey made important discoveries about the nature of deoxyribonucleic acid (DNA) and laid the groundwork for modern molecular genetics.
Highly regarded as an experimental scientist, Hershey is perhaps best known for the 1952 "blender experiment" that he and Martha Chase conducted to demonstrate that DNA, not protein, was the genetic material of life.
Hershey's work with bacteriophages, the viruses that prey on bacteria, was often carried out in loose collaboration with other scientists working with bacteriophages.
www.enotes.com /microbiology-encyclopedia/hershey-alfred-day   (157 words)

  
 Reference.com/Encyclopedia/Alfred Hershey
Alfred Day Hershey (December 4, 1908 – May 22 1997) was an American Nobel Prize-winning bacteriologist and geneticist.
He became director of the Carnegie Institution in 1962 and was awarded the Nobel Prize in Physiology or Medicine in 1969, shared with Luria and Delbrück for their discovery on the replication of viruses and their genetic structure.
After Hershey died, another phage worker, Frank Stahl, wrote: "The Phage Church, as we were sometimes called, was led by the Trinity of Delbrück, Luria, and Hershey.
www.reference.com /browse/wiki/Alfred_Hershey   (326 words)

  
 Alfred Day Hershey (www.whonamedit.com)
Alfred Hershey and Martha Chase in 1952 showed DNA to be the carrier of genetic information in virus reproduction, working with T2 phage.
Hershey received a letter from Max Delbrück, who said he had been reading Hershey's papers and was quite interested in a joint effort.
Hershey shared the Nobel Prize in 1969 with Salvador Edward Luria (1912-1991) and Max Ludwig Henning Delbrück (1906-1981), "for their discoveries concerning the replication mechanism and the genetic structure of viruses.
www.whonamedit.com /doctor.cfm/2099.html   (927 words)

  
 Alfred Day Hershey
Alfred Day Hershey was born December 4, 1908, in Owosso, Michigan, a small town near the state capital, to Robert D. and Alma (Wilber) Hershey.
Hershey then accepted a teaching and research position in the Department of Bacteriology at Washington University School of Medicine in St. Louis, specializing in bacteriology and immunology.
It is interesting to note that Hershey gave credit to his research assistant, a character trait that set him apart from many contemporary scientists.
www.personal-selection.com /AHershey.html   (497 words)

  
 Martha Chase Summary
Hershey was honored as one of the founders of molecular biology, and shared the 1969 Nobel Prize in medicine or physiology with Salvador Luria and Max Delbrück.
Hershey and Chase found that most of the bacteriophage DNA remained with the bacterial cells while their protein coats were released into the medium.
By marking bacteriophages with radioactive isotopes, Hershey and Chase were able to trace protein and DNA to determine which is the molecule of heredity.
www.bookrags.com /Martha_Chase   (985 words)

  
 Carolina: Science Quizzes: Hershey
Hershey was offered a position at Indiana University in 1950, but took a job at the Genetics Research Unit, Carnegie Institution of Washington at Cold Spring Harbor on Long Island, New York, because he preferred to work in a laboratory environment.
Hershey’s experiment led to the expressions (among research scientists) “Hershey heaven,” which is an experiment that can be repeated day after day with the same positive results and “Hershey’s circles,” which are a series of experiments that lead back to the beginning.
Hershey and Chase determined that the protein shell is a transporting mechanism for DNA, protecting it, attaching it to the host, and injecting it into the host.
www.carolina.com /quiz/hershey.asp   (553 words)

  
 Hershey - Search Results - MSN Encarta
Hershey, Milton (1857-1945), American manufacturer and philanthropist, best known as the founder of the Hershey Chocolate Company (now...
Hershey, Lewis B(laine) (1893-1977), American army general, who for three decades was director of the Selective Service System.
Hershey, Alfred Day (1908-1997), American geneticist and winner of the 1969 Nobel Prize in physiology or medicine, which he shared with...
ca.encarta.msn.com /Hershey.html   (143 words)

  
 Alfred Day Hershey
Delbruck incorrectly interpreted his results as specifically induced mutations, but Hershey and one of his students proved that the results they had obtained were recombinations by showing that the genetic processes in question correspond with the crossing-over of parts of similar chromosomes observed in cells of higher organisms.
Hershey is most noted for the so-called blender experiment that he performed with Martha Chase in 1952.
By showing that phage DNA is the principal component entering the host cell during infection, Hershey proved that DNA, rather than protein, is the genetic material of the phage.
medicine.nobel.brainparad.com /alfred_day_hershey.html   (242 words)

  
 Mayo Clinic Proceedings
Alfred Hershey was born on December 4, 1908, in Owosso, Mich (about 30 miles northeast of Lansing).
Hershey’s early research was on the chemistry of Brucella bacteria and in the area of immunology.
In 1952, Hershey and colleagues showed that during viral infection, the viral nucleic acid (and not the protein associated with it) enters the cell—that is, the genetic material is the nucleic acid, not the protein.
www.mayoclinicproceedings.com /inside.asp?AID=570&UID=   (533 words)

  
 [No title]
Alfred Hershey and Martha Chase at Cold Spring Harbor, 1953.
Alfred Hershey receiving the 1969 Nobel Prize in Physiology or Medicine.
Alfred Hershey and his son, Peter, at the Nobel Prize ceremonies.
www.dnaftb.org /dnaftb/concept_18/con18gallery.html   (145 words)

  
 ASM News Vol 67, Num 11,  November  2001, Reviews and Resources
The centerpiece was Hershey's evidence which confirmed through the Hershey-Chase blender experiments that DNA was the genetic material of inheritance.
Hershey focused on two phage systems: T-even phages (tadpole-like structures, as referred to by Hershey) for DNA inheritance and recombination, and phage lambda, which provided a mechanism for understanding cell-to-cell transfer and a mechanism for introducing (through specialized transduction) cellular genes into Escherichia coli.
Alfred Hershey and the Phage Group spawned multiple generations of phage users and lovers who opened the door to modern molecular biology.
newsarchive.asm.org /nov01/revres.asp   (1199 words)

  
 Sandwalk: Nobel Laureates Max Delbrück, Alfred D. Hershey, Salvador E. Luria
Max Delbrück (1906-1981), Alfred D. Hershey (1908-1997), and Salvador E. Luria (1912-1991) received the Nobel Prize in Physiology or Medicine for founding the phage group and stimulating hundreds of scientists to study molecular biology.
The constellation was promising: one physicist, Delbrück, one physician, Luria, and one biochemist, Hershey.
Therefore, Delbrück, Hershey and Luria must in fact be regarded as the original founders of the modern science of molecular biology.
sandwalk.blogspot.com /2007/09/nobel-laureates-max-delbrck-alfred-d.html   (1834 words)

  
 Experiments that Inspire
The experiment that Hershey and Chase devised to differentiate between these possibilities was simple and took advantage of the differences in the composition of protein and DNA.
Hershey and Chase added bacteriophage to cultures containing either radioactive sulfur or radioactive phosphorus.
Hershey and Chase now had two types of bacteriophages: one with a radioactive external protein coat, the other with highly radioactive DNA.
www.accessexcellence.org /AB/BC/Experiments_that_Inspire.html   (637 words)

  
 Genome Biology | Research news
Martha Chase, renowned for her part in the pivotal "blender experiment," which firmly established DNA as the substance that transmits genetic information, died of pneumonia on August 8 in Lorain, Ohio.
In 1952, Chase participated in what came to be known as the Hershey-Chase experiment in her capacity as a laboratory assistant to Alfred D. Hershey.
Hershey and Chase added marked bacteriophages to a fresh bacterial culture, allowing the phages to infect the bacteria by injecting their genetic material into the host cell.
genomebiology.com /researchnews/default.asp?arx_id=gb-spotlight-20030820-01   (929 words)

  
 Kitchen Blender Pegs DNA as Stuff of Life · Geek With Laptop
This Day in Tech - 1952: Geneticists Alfred Hershey and Martha Chase publish the findings of their so-called blender experiments, which conclude that DNA is where life’s hereditary data is found.
Hershey would subsequently share the 1969 Nobel Prize in Physiology or Medicine for his work in discovering the properties of DNA.
But Chase, who served as Hershey’s lab assistant during his experiments and whose name appears on the paper, was snubbed.
www.geekwithlaptop.com /kitchen-blender-pegs-dna-as-stuff-of-life   (275 words)

  
 Alfred D. Hershey - Biography
Alfred Hershey married Harriet Davidson in 1945, they have one son, Peter.
Alfred Hershey is a Member of the American Society for Microbiology, the National Academy of Sciences, and the American Academy of Arts and Sciences.
Hershey is Recipient of the Kimber Genetics Award of the National Academy of Sciences, 1965.
www.nobel.se /medicine/laureates/1969/hershey-bio.html   (221 words)

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