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Topic: Alkalosis

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In the News (Sun 21 Apr 19)

Metabolic alkalosis is caused by an excess of bicarbonate in blood.
Hypochloremic alkalosis is caused by an extreme lack or loss of chloride, such as may be caused by prolonged vomiting.
Hypokalemic alkalosis is caused by the kidneys' reaction to an extreme lack or loss of potassium which may be caused by some diuretic medications.
www.umm.edu /ency/article/001183.htm   (264 words)

 RxPG :: View topic - Metabolic Alkalosis due to Loss of which Ion? Tricky Q   (Site not responding. Last check: 2007-09-16)
Consequently, although metabolic alkalosis may be initiated by hydrogen ions lost from the body—for example, during gastric drainage—the maintenance of a sustained metabolic alkalosis requires that the net rate of renal bicarbonate reabsorption or renal bicarbonate generation, or both, be greater than normal.
The alkalosis of mineralocorticoid excess occurs primarily because of increased generation of bicarbonate by collecting duct segments (or, in other words, by increased renal acid excretion) and is clearly accentuated by potassium depletion.
The alkalosis occurs because of prolonged ingestion of absorbable alkali in patients with impaired renal function due to hypercalcemic nephropathy.
www.rxpgonline.com /modules.php?name=Forums&file=viewtopic&printertopic=1&t=5911&start=0&postdays=0&postorder=asc&vote=viewresult&popup=1   (1620 words)

 * Alkalosis - (Disease): Definition
ALKALOSIS - A metabolic derangement where the pH of the blood is abnormally high (basic).
Alkalosis describes a condition in which the amount of acid in the body is reduced.
Alkalosis: A dangerous decrease in the normal acidity of the blood.
en.mimi.hu /disease/alkalosis.html   (323 words)

 alkalosis - Hutchinson encyclopedia article about alkalosis
Alkalosis is due to an excessive loss of hydrogen ions due to vomiting.
It can also be due to excessive retention of bicarbonate ions by the kidney or to the ingestion of large amounts of alkalis, such as antacids.
The treatment of alkalosis is dependent upon removing the circumstances that lead to the disturbance in the acid-base balance of the body.
encyclopedia.farlex.com /alkalosis   (138 words)

 Respiratory Alkalosis | Principal Health News
Respiratory alkalosis is a condition where the amount of carbon dioxide found in the blood drops to a level below normal range.
Respiratory alkalosis is an alkali imbalance in the body caused by a lower-than-normal level of carbon dioxide in the blood.
The primary cause of respiratory alkalosis is hyperventilation.
www.principalhealthnews.com /topic/topic100587403   (638 words)

 Disease - Alkalosis - Hartford, Connecticut
Hypochloremic alkalosis is caused by an extreme lack or loss of chloride (may be caused by prolonged vomiting).
Alkalosis is usually treated by taking care of the cause rather than directly treating the pH.
For alkalosis caused by hyperventilation, breathing into a paper bag causes more carbon dioxide to be retained.
www.saintfranciscare.com /1873.cfm   (479 words)

 eMedicine - Metabolic Alkalosis : Article by Sameer Yaseen, MD
Bartter syndrome (see Hypokalemic Alkalosis with Hypercalciuria [OMIM]) is an inherited autosomal recessive disorder, in which reabsorption of sodium ions and chloride ions in the thick ascending loop of Henle is impaired, leading to their increased delivery to the distal nephron.
Possible mechanisms of alkalosis in hypokalemia are enhanced proximal bicarbonate reabsorption, stimulated renal ammonia genesis, impaired renal chloride reabsorption, reduced GFR (in animals), and intracellular acidosis in the distal nephron with subsequent enhanced hydrogen secretion.
In glucocorticoid-remediable hyperaldosteronism, metabolic alkalosis and hypertension are responsive to dexamethasone.
www.emedicine.com /med/topic1459.htm   (7322 words)

 Metabolic Alkalosis | Principal Health News
Metabolic alkalosis is a pH imbalance in which the body has accumulated too much of an alkaline substance, such as bicarbonate, and does not have enough acid to effectively neutralize the effects of the alkali.
Metabolic alkalosis, as a disturbance of the body's acid/base balance, can be a mild condition, brought on by vomiting, the use of steroids or diuretic drugs, or the overuse of antacids or laxatives.
If metabolic alkalosis is recognized and treated promptly, the patient may have no long-term complications; however, the underlying condition that caused the alkalosis needs to be corrected or managed.
www.principalhealthnews.com /topic/topic100587148   (632 words)

 Alkalosis - Wikipedia, the free encyclopedia
Alkalosis refers to a condition reducing hydrogen ion concentration of arterial blood plasma.
Generally alkalosis is said to occur when arterial pH exceeds 7.45.
Results from increased alveolar respiration leading to decreased plasma carbon dioxide concentration.
en.wikipedia.org /wiki/Alkalosis   (137 words)

 eMedicine - Alkalosis, Metabolic : Article Excerpt by: Margaret A Priestley, MD   (Site not responding. Last check: 2007-09-16)
Although metabolic alkalosis may not be referred to as often as metabolic acidosis, it is the most common acid-base abnormality in hospitalized adults.
The 2 types of metabolic alkalosis (ie, chloride-responsive, chloride-resistant) are classified based upon the amount of chloride in the urine.
Ionized calcium concentration: Metabolic alkalosis may cause a decrease in ionized calcium because of increased binding of calcium to plasma proteins; consequences include tetany and seizures.
www.emedicine.com /ped/byname/alkalosis-metabolic.htm   (532 words)

 eMedicine - Metabolic Alkalosis : Article Excerpt by: Sameer Yaseen, MD
The first clue to metabolic alkalosis is often an elevated bicarbonate concentration that is observed when serum electrolytes are obtained.
The pathogenesis of metabolic alkalosis involves 2 processes, the generation of metabolic alkalosis and the maintenance of metabolic alkalosis, events that usually overlap.
The generation of metabolic alkalosis occurs with the loss of acid, the gain of alkali, or the contraction of the extracellular fluid compart.....
www.emedicine.com /med/byname/metabolic-alkalosis.htm   (570 words)

 7.2 Metabolic Alkalosis - Causes - continued
Primary Hyperaldosteronism is a cause of 'saline-resistant' metabolic alkalosis.
Patients who present with hypokalaemic alkalosis of uncertain cause are often suspected of having this condition but other causes which may be denied by the patient should be considered eg surreptitious vomiting and/or use of diuretics for weight loss or psychological problems.
Metabolic alkalosis may be divided into two general groups based on the measured urinary chloride level.
www.qldanaesthesia.com /AcidBaseBook/AB7_2B.htm   (773 words)

 Respiratory Alkalosis   (Site not responding. Last check: 2007-09-16)
Effects of respiratory alkalosis and acidosis on myocardial blood flow and metabolism in patients with coronary artery disease.
Influence of acute and chronic respiratory alkalosis on preexisting chronic metabolic alkalosis.
Alkalosis attenuates hypoxic pulmonary vasoconstriction in neonatal lambs.
www.umdnj.edu /rspthweb/bibs/alkaresp.htm   (1728 words)

 eMedicine - Respiratory Alkalosis : Article by Jackie A Hayes, MD, FCCP
Respiratory alkalosis is the most common acid-base abnormality observed in patients who are critically ill. It is associated with numerous illnesses and is a common finding in patients undergoing mechanical ventilation.
Compensation for respiratory alkalosis is by increased renal excretion of bicarbonate.
The prognosis of respiratory alkalosis is variable and depends on the underlying cause and the severity of the underlying illness.
www.emedicine.com /med/topic2009.htm   (2129 words)

 7.2 Metabolic Alkalosis - Causes
For example it may be used to describe the initiating process, or the process maintaining the disorder or it can be used to refer to the combination of both processes, so be mindful of this when reading the rest of this section as otherwise you may become a little confused.
Maintenance of the alkalosis requires a process which greatly impairs the kidney's ability to excrete bicarbonate and prevent the return of the elevated plasma level to normal.
The patients on diuretics who develop an alkalosis are those who are also volume depleted (increasing aldosterone levels) and have a low dietary chloride intake ('salt restricted' diet).
www.anaesthesiamcq.com /AcidBaseBook/ab7_2.php   (1416 words)

 Alkalosis: Acid-Base Balance: Merck Manual Home Edition
Alkalosis is excessive blood alkalinity caused by an overabundance of bicarbonate in the blood or a loss of acid from the blood (metabolic alkalosis), or by a low level of carbon dioxide in the blood that results from rapid or deep breathing (respiratory alkalosis).
Respiratory alkalosis develops when rapid, deep breathing (hyperventilation) causes too much carbon dioxide to be expelled from the bloodstream.
When respiratory alkalosis is caused by anxiety, a conscious effort to slow breathing may make the condition disappear.
www.merck.com /mmhe/sec12/ch159/ch159c.html   (371 words)

 Infant Metabolic Alkalosis and Soy-Based Formula -- United States
After diagnosis of the alkalosis, infants who were placed on chloride supplement responded favorably; those who, after treatment for and recovery from the alkalosis, went back on the formula -- but without chloride supplementation -- had a recurrence.
Insufficient intake of chloride is a known cause of metabolic alkalosis.
The original diagnosis of these cases was Bartter syndrome, a condition that causes metabolic alkalosis from renal loss of potassium and requires a large replacement dose of potassium chloride throughout life to maintain metabolic homeostasis.
www.cdc.gov /mmwr/preview/mmwrhtml/00044475.htm   (1462 words)

 Metabolic Alkalosis   (Site not responding. Last check: 2007-09-16)
Metabolic alkalosis is a primary pathophysiologic event characterized by the gain of bicarbonate or the loss of nonvolatile acid from extracellular fluid.
Clinical states associated with metabolic alkalosis are vomiting, mineralocorticoid excess, the adrenogenital syndrome, licorice ingestion, diuretic administration, and Bartter's and Gitelman's syndromes.
Subsequently, the generation and maintenance of metabolic alkalosis is described, followed by a summary of the specific conditions associated with this disorder.
www.rcjournal.com /contents/04.01/04.01.0354.asp   (385 words)

 Mediators of alkalosis-induced relaxation in pulmonary arteries from normoxic and chronically hypoxic piglets -- Gordon ...
Alkalosis caused a significant decrease in tension in all groups (*).
Alkalosis caused a significant decrease in tension in both groups (*).
The effect of alkalosis on hypoxia-induced pulmonary vasoconstriction in lungs of newborn rabbits.
ajplung.physiology.org /cgi/content/full/276/1/L155   (4124 words)

 7.3 Metabolic Alkalosis - Maintenance   (Site not responding. Last check: 2007-09-16)
The four factors that cause maintenance of the alkalosis (by increasing bicarbonate reabsorption in the tubules or decreasing bicarbonate filtration at the glomerulus) are:
The idea is that hypovolaemia is associated with increased fluid and sodium reabsorption in the proximal tubule and bicarbonate is reabsorbed in preference to chloride; the alkalosis thus being maintained.
For an alkalosis to develop in patients on diuretic therapy, there generally has to some decrease in chloride intake as well (eg if the patient is on a 'salt restricted' diet).
www.qldanaesthesia.com /AcidBaseBook/AB7_3.htm   (384 words)

 Mediators of alkalosis-induced relaxation of piglet pulmonary veins -- Halla et al. 278 (5): 968 -- AJP - Lung Cellular ...
Alkalosis caused a greater absolute decrease in tension in Con high-tension veins.
of alkalosis on pulmonary hemodynamics and fluid filtration in
Discordant effects of alkalosis on elevated pulmonary vascular resistance and vascular reactivity in lamb lungs.
ajplung.physiology.org /cgi/content/full/278/5/L968   (3314 words)

 UpToDate Causes of metabolic alkalosis
— Metabolic alkalosis is a relatively common clinical problem that is most often induced by diuretic therapy or the loss of gastric secretions due to vomiting (which may be surreptitious) or nasogastric suction.
In normal subjects, gastric hydrogen secretion does not lead to metabolic alkalosis, since it is matched to pancreatic bicarbonate secretion that is stimulated as the acid enters the duodenum.
Although the hydroxide or carbonate component of the antacid buffers gastric hydrogen, this is balanced by the combination of most of the cation component of the antacid (magnesium, aluminum, or calcium) with pancreatic bicarbonate [8].
patients.uptodate.com /topic.asp?file=fldlytes/23871   (518 words)

 MoonDragon's Health & Wellness: Alkalosis
Alkalosis is less common than acidosis, and produces over excitability of the nervous system.
Alkalosis is often the result of excessive intake of alkaline drugs, such as sodium bicarbonate for the treatment of gastritis or peptic ulcers.
Prolonged hyperventilation may cause temporary alkalosis, resulting in anxiety and a feeling that one cannot get enough air, despite the fact that breathing itself is not actually restricted in any way.
www.moondragon.org /health/disorders/alkalosis.html   (731 words)

 Metabolic alkalosis (Treatment Guide)
METABOLIC ALKALOSIS DEFINITION A primary rise in plasma bicarbonate concentration to greater than 28 mEq/L. This may be due to: * loss of acid from extracellular fluid in the urine or stool, or in acid-containing gastric juice (e.g.
In severe potassium deficiency, alkalosis cannot be corrected until potassium is repleted.
In severe metabolic alkalosis, cardiac and respiratory monitoring is needed.
www.intox.org /databank/documents/treat/treate/trt35_e.htm   (379 words)

 7.1 Metabolic Alkalosis: Definition   (Site not responding. Last check: 2007-09-16)
A metabolic alkalosis is a primary acid-base disorder which causes the plasma bicarbonate to rise to a level higher than expected.
An elevation in bicarbonate occurring in response to a chronic respiratory acidosis should be referred to as a 'compensatory response' and never as a ‘secondary metabolic alkalosis’.
You should be aware that many articles (esp in the surgical literature) will refer to a 'compensated metabolic alkalosis' as a 'metabolic alkalosis with a (secondary) respiratory acidosis'.
www.anaesthesiamcq.com /AcidBaseBook/ab7_1.php   (163 words)

 6.3 Respiratory Alkalosis - Maintenance   (Site not responding. Last check: 2007-09-16)
The alkalosis persists as long as the initiating disorder is acting
The alkalosis persists as long as the initiating disorder persists unless some other disorder or complication causing impairment of the hyperventilation intervenes.
This is different to the situation with a metabolic alkalosis where maintenance of the disorder requires an abnormality to maintain it as well as the problem which initiated it.
www.qldanaesthesia.com /AcidBaseBook/AB6_3.htm   (310 words)

 Acidosis and Alkalosis   (Site not responding. Last check: 2007-09-16)
Alkalosis occurs when [bicarbonate] increases forcing the equilibrium to remove protons from blood causing blood pH to rise.
Temporary metabolic alkalosis occurs when there is an intake of sodium bicarbonate e.g.
Respiratory alkalosis can be induced by hyperventilation i.e.
www-biol.paisley.ac.uk /courses/stfunmac/glossary/acidosis.html   (264 words)

 Blood Gas Text
Metabolic alkalosis may be found in vegetarians and fad dieters who are ingesting a low-protein, high fruit diet.
This respiratory alkalosis is a separate effect from the metabolic acidosis produced by aspirin.
And alkalosis caused by too much bicarbonate is positively deadly for the arrest victim.
www.madsci.com /manu/gas_acid.htm   (2425 words)

 Metabolic Alkalosis Contributes to Acute Hypercapnic Respiratory Failure in Adult Cystic Fibrosis -- Holland et al. 124 ...
Metabolic Alkalosis Contributes to Acute Hypercapnic Respiratory Failure in Adult Cystic Fibrosis -- Holland et al.
and metabolic alkalosis was evident in 71% of CF patients and
alkalosis due to the role of albumin as a weak nonvolatile acid.
www.chestjournal.org /cgi/content/full/124/2/490   (2018 words)

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