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Topic: Allantoin

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	Allantoin, Supplement Monograph - Flora Health Supplement Encyclopedia
		Allantoin is said to clean away dead (necrotic) tissue and hasten the growth of new healthy tissue.
		Allantoin is the soothing and healing constituent in comfrey root, valued for use in creams and lotions for these properties.
		Allantoin, in its pure form, is a white, odourless, crystalline powder, soluble in water and alcohol and almost insoluble in ether.
	www.florahealth.com /flora/home/Canada/HealthInformation/Encyclopedias/Allantoin.asp (2473 words)

	Allantoin - Wikipedia, the free encyclopedia
		Allantoin is a botanical extract of the comfrey plant and is used for its healing, soothing, and anti-irritating properties.
		Allantoin helps to heal wounds and skin irritations and stimulate growth of healthy tissue.
		The keratolytic effect and abrasive and astringent properties of allantoin are used in skin softening cosmetic preparations.
	en.wikipedia.org /wiki/Allantoin (189 words)

	ALLANTOIN (5-UREIDOHYDANTOIN)
		Allantoin, the diureide of glyoxylic acid, is a crystallizable oxidation product of uric acid found in allantoic and amniotic fluids, in fetal urine and in many plants.
		Allantoin is active in skin-softening (keratolytic effect) and rapid cell regeneration by precipitating proteins on skin.
		Allantoin has been used in various oral hygeine preparations such as toothpaste and mouthwash as well as in eye drops to treat watering eyes and in ear drops to clean the ear canal.
	www.chemicalland21.com /arokorhi/lifescience/phar/ALLANTOIN.htm (473 words)

	Elicina Europe Ingredients
		Allantoin has been also termed a counter irritant that helps alleviate the untoward skin-irritation effects of certain cosmetic ingredients such as soap and detergent surfactants, oils and acidic or alkaline materials.
		Allantoin has long been known to enhance the efficacy and desirability of cosmetic creams and lotions by its action as a skin protectant.
		Allantoin is considered to be non-toxic, non-irritating and non-allergenic by the Schwartz patch test on 200 individuals, as published in the Federal Register (Volume 43, No. 151, pp.
	www.elicinaeurope.com /allantoin.html (568 words)

	ISTC - Allantoin preserves pregnancy
		Primates are unable to synthesize allantoin, but they cannot live without it and they obtain it from their food.
		Allantoin raises the resistance of cells to oxidative stress (verified on the colon bacillus).
		However, the major role of allantoin could be said to be the fact that it provides for embryo development.
	www.istc.ru /istc/sc.nsf/news/science-news-allantoin-preserves-pregnancy.htm (261 words)

	Shea butter and other natural ingredients of Cottage Essentials from Advanced Inc.
		Allantoin is a healing, moisturizing, soothing and anti-irritating natural component found in wheat germ, rice polishings, comfrey root, earthworms, and as an organic component of many soils.
		Allantoin has a pronounced keratolytic and skin softening action, acts as chemical debrider of necrotic and scaling tissue.
		Allantoin is used in the treatment of skin ulcers, wounds, burns and sunburns, acne and skin eruptions, abrasions, impetigo, eczema and psoriasis.
	www.advancedinc.org /natural-ingredients.htm (1264 words)

	[No title] (Site not responding. Last check: 2007-10-13)
		Allantoin is a commonly used ingredient in cosmetic applications, particularly for skin creams, where it exerts a skin protective function.
		allantoin; and (2) an emulsifier system comprising: (a) an acidic anionic polymer; and (b) an anionic emulsifier that is substantially hydrophilic and is soluble in water, the pH of the composition being adjusted to a range of from about 3.0 to about 6.0.
		A composition comprising an oil-in-water emulsion comprising: (a) allantoin; and (b) at least one anionic or nonionic emulsifier that is substantially hydrophilic and is soluble in water; wherein the pH of the composition is in a range of from about 3.0 to about 6.0.
	www.wipo.int /cgi-pct/guest/getbykey5?KEY=01/87232.011122&ELEMENT_SET=DECL (10926 words)

	Simultaneous Measurement of Allantoin and Urate in Plasma: Analytical Evaluation and Potential Clinical Application in ...
		of allantoin as a biomarker of oxidative stress, the hypothesis being
		Allantoin and urate concentrations in biological fluids, as reported in current and previous studies.
		Grootveld M, Halliwell B. Measurement of allantoin and uric acid in human body fluids: a potential index of free-radical reactions in vivo?.
	www.clinchem.org /cgi/content/full/45/6/901 (2110 words)

	ResQ Labs (Site not responding. Last check: 2007-10-13)
		Allantoin enhances the efficacy and desirability of cosmetic creams and lotions by its action as a skin protectant.
		Allantoin has been incorporated into shampoos, lipsticks, shaving creams, suntan products, bath foams, hair gels, baby powders and various aerosol preparations.
		Allantoin is considered to be nontoxic, nonirritating and non-allergenic by the Schwartz patch test on 200 individuals, as published in the Federal Register (Volume 43, No. 151, pp.
	www.resq-labs.com /ac/stores/4/webpage.aspx?UserID=62417&SessionID=5BeNUAJjbXJdUNTPhQcM&SID=4&Category_ID=&Webpage_ID=37 (454 words)

	[No title] (Site not responding. Last check: 2007-10-13)
		allantoin; and (2) an emulsifier system comprising: (a) an acidic anionic polymer; and (b) a polyethylene glycol ester of stearic acid.
		In yet another alternative embodiment, the allantoin-containing composition comprises an oil-in-water emulsion comprising: (1) allantoin; (2) a carbohydrate polymer; and (3) an emulsifier system comprising: (a) beeswax; and (b) an anionic emulsifier that is substantially hydrophilic and is soluble in water.
		Yet another embodiment of a method according to the present invention employs a composition comprising an oil-in-water emulsion comprising: (1) allantoin; (2) a carbohydrate polymer; and (3) an emulsifier system comprising: (a) beeswax; and (b) an anionic emulsifier that is substantially hydrophilic and is soluble in water.
	www.wipo.int /cgi-pct/guest/getbykey5?KEY=01/87301.011122&ELEMENT_SET=DECL (11316 words)

	Merck KGaA - RonaCare® Allantoin - (Site not responding. Last check: 2007-10-13)
		The main effect of allantoin is the powerful stimulation of cell proliferation and the enhancement of the rebuilding of intact granulation tissue.
		In cosmetics, allantoin is used as an adjunct in numerous preparations, where it enhances soothing, cleansing and healing action.
		The amphoteric character of allantoin has a substantive effect on skin and hair, which prolongs keratolytic activity.
	www.merck.de /servlet/PB/menu/1284800 (150 words)

	Allantoin (Site not responding. Last check: 2007-10-13)
		Allantoin is compatible with most ingredients used in personal care formulations.
		To incorporate 0.5% Allantoin, or more, into an emulsion product, the emulsion is made and Allantoin is added during the cooling process below 50 °C. Good agitation is required to thoroughly disperse the Allantoin to achieve a suitable suspension.
		Addition of Allantoin at 0.5% or more or at temperatures above 50 °C in aqueous systems can cause solubilization and recrystallization upon cooling into larger particles which are perceptible during product use.
	www.ispcorp.com /products/hairskin/content/skincare/brochure/allantoin/formulating.html (118 words)

	MMS - Lotion Supplies
		Allantoin is also used to hasten the growth of new, healthy tissue.
		Allantoin is considered to be nontoxic, nonirritating and non-allergenic.
		Allantoin is safe and effective in the dosage range recommended (0.5 to 2.0%) as a skin protectant.
	www.thesage.com /catalog/LotionSupplies.html (2373 words)

	Allantoin, Do You Use It ? - The Soap Dish Forum (Site not responding. Last check: 2007-10-13)
		"allantoin is compatible with a large number of drugs used in pharmaceutical and dermatological preparations and cosmetics, so that all types of combinations are possible for preparations with specific uses.
		Allantoin may therefore also be incorporated without difficulty in specialties already available.
		The Allantoin that you are using is not derived or extracted from Comfrey.
	www.soapdishforum.com /forum/index.php?showtopic=5172 (1364 words)

	Medscape MEDLINE search:
		Allantoin net flux through the plasma allantoin compartment was determined in sheep given a roughage diet by means of a continuous infusion of [4,5-14C]allantoin for 17 h.
		The allantoin regulon of Escherichia coli, formed by three operons expressed from promoters allA(P), gcl(P) and allD(P), is involved in the anaerobic utilization of allantoin as nitrogen source.
		Effects of amount of intake and stage of forage maturity on urinary allantoin excretion and estimated microbial crude protein synthesis in the rumen of steers.
	search.medscape.com /uslclient/searchMedline.do?searchstring=Allantoin&cid=med (1189 words)

	Marine Screen (Site not responding. Last check: 2007-10-13)
		Allantoin has been termed a cell proliferant, an epithelization stimulant, and a chemical debrider.
		The FDA acknowledges that.5-2% Allantoin can be used for the treatment of chafed, chapped, cracked, sunburned, or windburned skin or lips.
		Clinical and marketing experience has confirmed that Allantoin is safe in the dosage range as a skin protestants for adults, children and infants.
	www.sunology.net /tech_facts.htm (240 words)

	Factors Affecting Application of Milk Allantoin as an Estimator of Microbial Protein Flow to the Duodenum Under ...
		Evaluation of milk allantoin excretion as an index of microbial protein supply in lactating dairy cows.
		The excretion of allantoin by ruminants in relation to protein entering the abomasum.
		Estimation of the flow of microbial nitrogen to the duodenum using milk uric acid or allantoin.
	jds.fass.org /cgi/content/full/86/5/1716 (2602 words)

	A Novel Superfamily of Transporters for Allantoin and Other Oxo Derivatives of Nitrogen Heterocyclic Compounds in ...
		of a yeast mutant deficient in allantoin uptake was used.
		genes is induced in the presence of allantoin or its degradative
		Yoo, H.S., Cunningham, T.S., and Cooper, T.G. The allantoin and uracil permease gene sequences of Saccharomyces cerevisiae are nearly identical.
	www.plantcell.org /cgi/content/full/14/4/847 (4127 words)

	glarre "Akema fine chaemicals/italy"
		Allantoin is a healing, moisturizing, soothing and anti-irritating, keratolytic and non-toxic agent useful in dermatological, cosmetic and veterinary preparation.
		Allantoin has a pronounced keratolytic and skin softening action, acts as chemical derider of necrotic and scaling tissue, cleansing up the areas where applied.
		As natural component, Allantoin was found in fetal Allantoic fluid, in wheat germ, rice polishings, confrey roots, in dog urine and in the urine of pregnant women, in the earth-worm and as organic component of many soils.
	www.glarre.com /akema.html (1075 words)

	Identification of Allantoin, Uric Acid, and Indoxyl Sulfate as Biochemical Indicators of Filth in Food Packaging by LC (Site not responding. Last check: 2007-10-13)
		A liquid chromatographic (LC) method was developed for the determination of allantoin, uric acid, and indoxyl sulfate in mammalian urine contaminated packaging material including paper bagging, corrugated cardboard, grayboard, and burlap bagging.
		The procedure involves solvent extraction and isolation of the 3 analytes by reversed-phase LC with ultraviolet detection at 225 nm for allantoin and 286 nm for uric acid and indoxyl sulfate.
		Recoveries of allantoin, uric acid, and indoxyl sulfate from 11 fortified samples (4 types) for both mouse and rat urine ranged from 28.2 to 114.1% for allantoin; 32.6 to 123.4% for uric acid; and 52.6 to 118.2% for indoxyl sulfate.
	www.aoac.org /pubs/JOURNAL/2001/May_June/Identification_of_Allantoin.htm (280 words)

	Government and academic resources on ALLANTOIN
		Physiological Ecology of Fat sand rats: This precipitate consisted of pure allantoin and it accounted for 29% of the mass of the urine and 30% of the total nitrogen excreted per day.
		Urate Oxidase and Ureide Metabolism:...has long been classified as a copper-dependent enzyme, and the reaction is usually described in textbooks as the O 2 -dependent conversion of urate to allantoin...
		Apios americana: Whether or not the plant exports its fixed nitrogen as ureides (allantoin, allantoic acid) as is typical of many of the subtropical Phaseoleae or as the more...
	names.mongabay.com /drugs/ingredients/ALLANTOIN.html (525 words)

	Allopurinol
		Allantoin is readily water soluble and easily excreted in urine.
		Uric acid is not as soluble in water as allantoin and begins to form crystals which can show up as kidney stones (especially in human patients), bladder stones (especially in Dalmatians and in dogs with liver shunts), joint deposits (birds or humans with gout) or other unpleasant places.
		Whether the problem is natural inability to produce allantoin (birds), inability to get uric acid into liver cells for conversion to allantoin (Dalmatians and animals with liver shunts) or excessive purine intake, the goal is to reduce uric acid production.
	www.marvistavet.com /html/body_allopurinol.html (514 words)

	Urinary Allantoin:Creatinine Ratios in White-tailed Deer (Site not responding. Last check: 2007-10-13)
		Consequently, we determined that in cattle and sheep at maintenance, allantoin derived from tissue turnover (i.e., endogenous) contributes roughly 17-19% of the allantoin to the A:C ratio.
		Chen (1989) noted that 24-h urinary allantoin excretion in steers increased by 33% during the first 3 days of fasting; however, the results of studies of the effects of short-term fasting in sheep have been inconsistent (Rys et al.
		Study focused on 24-h urinary excretion of endogenous allantoin, applying methods used with domestic ruminants (e.g., intragastric infusion), would be useful for improving our understanding of the influence of tissue catabolism on A:C ratios at various planes of nutrition and physical condition.
	www.npwrc.usgs.gov /resource/2001/acratio/disc.htm (1934 words)

	Effect of Diet on Milk Allantoin and Its Relationship with Urinary Allantoin in Dairy Cows -- Gonda and Lindberg 80 ...
		allantoin in milk and urine of dairy cows.
		of allantoin in milk was correlated with its concentration in
		the proportion of allantoin excreted in milk was not constant
	jds.fass.org /cgi/content/abstract/80/2/364 (436 words)

	Publication Details - Wolf B. Frommer - Stanford University School of Medicine
		By functional complementation of a yeast mutant defective in allantoin uptake, an Arabidopsis transporter, AtUPS1 (Arabidopsis thaliana ureide permease 1), was identified.
		Transport of (14)C-labeled allantoin by AtUPS1 in yeast exhibited saturation kinetics (K(m) approximately 52 microM), was dependent on Glc and a proton gradient, and was stimulated by acidic pH.
		Protons are cosubstrates in allantoin transport by AtUPS1, as demonstrated by expression in Xenopus laevis oocytes.
	www-med.stanford.edu /profiles/frdActionServlet?choiceId=showPublication&pubid=47997&fid=6305 (240 words)

	Allantoin (Site not responding. Last check: 2007-10-13)
		Allantoin helps alleviate and prevent symptoms of irritated and dry skin, and dry and chapped lips.
		A skin protectant is a drug which protects injured or exposed skin or mucous membrane surfaces from harmful or annoying stimuli.
		When 0.5% to 2.0% Allantoin is added to cosmetic and personal care products and no claims are made related to Allantoin, the product remains a cosmetic.
	www.ispcorp.com /products/hairskin/content/skincare/brochure/allantoin/keyfeat.html (208 words)

	Allantoin in a natural form - AbateIT.com (Site not responding. Last check: 2007-10-13)
		Allantoin promotes wound healing and speeds cell regeneration.
		Based on the wide use and clinical acceptance of Allantoin, as well as published reports in the literature, the FDA has approved the following statements for non-prescription, drug products containing Allantoin at 0.5% to 2.0%.
		The U.S. Food and Drug Administration acknowledges that Allantoin at 0.5 to 2.0% concentration can be used for the prevention and treatment of chafed, chapped, cracked, sunburned or wind burned skin or lips, cold sores, fever blisters and diaper rash, but considers such explicit claims as drug claims.
	abateit.com /hervi-allantoin.htm (991 words)

	Progress in analytical methods
		On a C18 reversed-phase column, allantoin is not retained long enough for good separation from the polar solutes, thus the column length often needs to be extended by using two columns [215-222].
		The weakness is that when the concentration is low, the accuracy of allantoin measurement is affected since the allantoin peak is not well separated from the unidentified background noise when monitored at around 200 nm wavelength.
		In general, with the analysis of derivatized allantoin, the run time is short and analysis robust, but other purine derivatives are not included within the same run.
	www.iaea.org /programmes/nafa/d3/purine-cd/html/review/html/22_2_7.htm (469 words)

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