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Topic: Alteplase

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	alteplase - Heart Disease and other cardiovascular conditions on MedicineNet.com
		DRUG CLASS AND MECHANISM: Alteplase is an injectable drug, given directly into a vein, that is used to treat conditions caused by arterial blood clots including heart attacks, strokes, chest pain at rest (unstable angina), blood clots in the lungs (pulmonary thrombosis), and other less common conditions involving blood clots.
		Alteplase is an enzyme that occurs naturally in man and causes blood clots to dissolve.
		PRESCRIBED FOR: Alteplase is used to treat persons with heart attacks (acute myocardial infarctions), strokes, chest pain at rest (unstable angina), blood clots in the lungs (pulmonary thrombosis or embolism), and other less common conditions involving blood clots.
	www.medicinenet.com /alteplase/article.htm (518 words)

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	Activase (Alteplase) drug description - prescription drugs and medications at RxList
		It is a sterile, purified glycoprotein of 527 amino acids.
		It is synthesized using the complementary DNA (cDNA) for natural human tissue-type plasminogen activator obtained from a human melanoma cell line.
		The manufacturing process involves the secretion of the enzyme alteplase into the culture medium by an established mammalian cell line (Chinese Hamster Ovary cells) into which the cDNA for alteplase has been genetically inserted.
	www.rxlist.com /cgi/generic/alteplas.htm (221 words)

	Alteplase.com - The official site for alteplase information
		Alteplase is used to treat people who have suffered heart attacks (acute myocardial infarctions), strokes, chest pain at rest (unstable angina), blood clots in the lungs (pulmonary thrombosis or embolism), and other less common conditions involving blood clots.
		Alteplase for the Treatment of Central Venous Catheter Occlusion in Children: Results of a Prospective, Open-label, Single-arm Study (The Cathflo Activase Pediatric Study).
		PURPOSE: Alteplase is approved for use in the restoration of function to occluded central venous...
	www.alteplase.com (454 words)

	Genentech: Products - Product Information - Activase Full Prescribing Information
		The clearance of Alteplase in AMI patients has shown that it is rapidly cleared from the plasma with an initial half-life of less than 5 minutes.
		Activase® (Alteplase) is indicated for use in the management of acute myocardial infarction in adults for the improvement of ventricular function following AMI, the reduction of the incidence of congestive heart failure, and the reduction of mortality associated with AMI.
		Activase® (Alteplase) is indicated for the management of acute ischemic stroke in adults for improving neurological recovery and reducing the incidence of disability.
	www.gene.com /gene/products/information/cardiovascular/activase/insert.jsp (7070 words)

	Heart And Vascular Diseases - Evaluation, Treatment and Research at the National Heart, Lung and Blood Institute
		In the study described here patients are treated with an agent, alteplase, intended to make the clot dissolve within only a few days.
		Alteplase is injected directly into the clots through a thin tube under x-ray guidance.
		The current study is testing a much lower dose of alteplase than has been used in the past with the hope that this will enhance the safety of the treatment without compromising its effectiveness.
	patientrecruitment.nhlbi.nih.gov /HeartDiseases.aspx (721 words)

	Alteplase definition - Medical Dictionary definitions of popular medical terms
		Alteplase definition - Medical Dictionary definitions of popular medical terms
		Our Alteplase Main Article provides a comprehensive look at the who, what, when and how of Alteplase
		Alteplase: Generic name of a tissue plasminogen activator produced by recombinant DNA technology.
	www.medterms.com /script/main/art.asp?articlekey=40691 (115 words)

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