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Topic: Amiloride

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	Amiloride citrate - Patent 4190655
		Amiloride citrate, since it is relatively water insoluble would be virtually tasteless and hence, would lend itself easily to the preparation of chewable tablets which can be used, for example, in the pediatric market.
		Amiloride citrate, therefore, is useful in combination with other classes of diuretic agents to prevent the loss of potassium which the other diuretcis otherwise would cause to be eliminated.
		Amiloride citrate is advantageously administered at a dosage range of from about 5 mg/day to about 30 mg/day preferably at 5 mg/day to about 20 mg per day or at a somewhat higher or lower dosage at the physician's discretion, preferably in sub-divided amounts on a 2 to 4 times a day regimen.
	www.freepatentsonline.com /4190655.html (1300 words)

	Amiloride Blockades Lipopolysaccharide-Induced Proinflammatory Cytokine Biosynthesis in an Ikappa B-alpha /NF-kappa ...
		Amiloride Blockades Lipopolysaccharide-Induced Proinflammatory Cytokine Biosynthesis in an Ikappa B-alpha /NF-kappa B-Dependent Mechanism.
		Amiloride and HMA suppressed the phosphorylation of I
		to amiloride in the absence or presence of
	ajrcmb.atsjournals.org /cgi/content/full/26/1/114 (5599 words)

	Amiloride Hydrochloride (PIM 026)
		Though amiloride has mild hypotensive activity, the medication is generally used concurrently with a thiazide or a loop diuretic to prevent or treat diuretic-induced hypokalemia.
		Amiloride should be used with extreme caution in patients with impaired renal function, diabetes mellitus, or in the elderly.
		Amiloride decreases sodium reabsorption in the distal tubule by inhibiting cellular sodium transport mechanism such as the conductive sodium influx pathway and possibly the sodium-hydrogen exchange system.
	www.intox.org /databank/documents/pharm/amilorid/pim026.htm (1758 words)

	Effects of Topically Delivered Benzamil and Amiloride on Nasal Potential Difference in Cystic Fibrosis -- HOFMANN et ...
		Amiloride inhalation therapy in cystic fibrosis: influence on ion content, hydration, and rheology of sputum.
		Amiloride in cystic fibrosis: safety, pharmacokinetics, and efficacy in the treatment of pulmonary disease.
		Inhibitory potency of amiloride, benzamil and phenamil on sodium conductances in primary cultured cystic fibrosis nasal epithelium (abstract).
	ajrccm.atsjournals.org /cgi/content/full/157/6/1844 (4221 words)

	Amiloride
		Nevertheless, persons taking more than 300 mg of magnesium per day and amiloride should consult with a doctor, as this combination may lead to potentially dangerous elevations in levels of magnesium in the body.
		The effects of amiloride and triamterene on urinary magnesium excretion in conscious saline-loaded rats.
		Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients.
	www.gianteagle.com /healthnotes/Drug/Amiloride.htm (602 words)

	Amiloride Disrupts NaCl versus KCl Discrimination Performance: Implications for Salt Taste Coding in Rats -- Spector et ...
		Amiloride exerted a potent influence on salt discrimination performance in a monotonic dose-dependent manner.
		Nejad MS (1986) The neural activities of the greater superficial petrosal nerve of the rat in response to chemical stimulation of the palate.
		Ninomiya Y, Funakoshi M (1988) Amiloride inhibition of responses of rat single chorda tympani fibers to chemical and electrical tongue stimulations.
	www.jneurosci.org /cgi/content/full/16/24/8115 (4746 words)

	Neural Representation of Salts in the Rat Solitary Nucleus: Brain Stem Correlates of Taste Discrimination -- John and ...
		Amiloride treatment caused these 2 sets of salt stimuli, originally far apart in the taste space, to group together, reflecting an increasing similarity in their across-neuron patterns.
		Amiloride treatment (triangles) caused these 2 sets of salt stimuli, originally far apart in the taste space (circles), to group together, reflecting an increasing similarity in their across-neuron patterns and a distinct difference from the pattern to unadulterated NaCl (+).
		Amiloride inhibited the responses of N-best cells to 0.1 M NaCl across the extended amiloride concentration range.
	jn.physiology.org /cgi/content/full/84/2/628 (6836 words)

	Amiloride-sensitive epithelial Na+ channel currents in surface cells of rat rectal colon -- Inagaki et al. 286 (2): ...
		of amiloride (I) and in its absence (I
		Currents were elicited in the absence (control) and presence of external amiloride (10 µM) by applying ramp command voltages, each of 800-ms duration, from –69 to +41 mV.
		Amiloride (10 µM)-insensitive whole cell current amplitudes normalized to values at –63 mV in the presence of 150 mM Na in the bath solution are plotted against membrane potentials.
	ajpcell.physiology.org /cgi/content/full/286/2/C380 (7469 words)

	Effects of Amiloride on Gustatory Neural Responses to Salts in the Frog -- Kitada et al. 26 (9): 1203 -- Chemical Senses
		In amiloride treatment, adapting solution containing 0.5 mM amiloride was applied to the tongue for 1 min prior to each test and then stimulating solution containing 0.5 mM amiloride was applied.
		The magnitude of the neural response to 0.5 M NaCl without amiloride is taken as unity on the ordinate.
		In amiloride treatment, adapting solution with amiloride of various concentrations (0.05-0.5 mM) was applied to the tongue for 1 min prior to each test and then stimulating solution containing the same concentration of amiloride as that in the adapting solution was applied to the tongue.
	chemse.oxfordjournals.org /cgi/content/full/26/9/1203 (3613 words)

	Amiloride-sensitive sodium signals and salt appetite: multiple gustatory pathways -- Roitman and Bernstein 276 (6): ...
		Amiloride treatment and CT transection each appeared to reduce the NaCl intake of sham drinking rats.
		Amiloride is an ineffective conditioned stimulus in taste aversion learning.
		Amiloride inhibition of responses of rat single chorda tympani fibers to chemical and electrical tongue stimulations.
	ajpregu.physiology.org /cgi/content/full/276/6/R1732 (4351 words)

	amiloride of Augusta, Georgia
		Amiloride is in a class of drugs called potassium-sparing diuretics (water pills).
		Amiloride is used to treat edema (swelling) and hypertension (high blood pressure).
		Amiloride is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby.
	www.universityhealth.org /15822.cfm (1200 words)

	Mutations in the Epithelial Na+ Channel ENaC Outer Pore Disrupt Amiloride Block by Increasing Its Dissociation Rate -- ...
		G525C in the absence or the presence of amiloride or benzamil, as indicated in the figure.
		Kleyman TR and Cragoe EJ Jr (1988) Amiloride and its analogs as tools in the study of ion transport.
		Li JH, Cragoe EJ Jr, and Lindemann B (1985) Structure-activity relationship of amiloride analogs as blockers of epithelial Na channels: I. Pyrazine-ring modifications.
	molpharm.aspetjournals.org /cgi/content/full/64/4/848 (5036 words)

	Amiloride-induced contraction of isolated guinea pig, mouse, and human fetal airways -- Christ et al. 274 (1): 209 -- ...
		The effect of amiloride on the airway response to metabisulphite in asthma: a negative report.
		Amiloride and its analogs as tools in the study of ion transport.
		Effect of inhaled amiloride on the bronchial response to methacholine and cold air hyperventilation challenges.
	ajpregu.physiology.org /cgi/content/full/274/1/R209 (3221 words)

	hydrochlorothiazide and amiloride (Site not responding. Last check: 2007-10-29)
		Hydrochlorothiazide and amiloride is in the FDA pregnancy category B. This means that it is not expected to harm an unborn baby.
		Hydrochlorothiazide and amiloride should begin working about 4 to 6 hours after you take your medication, but it may be a few weeks before you see an improvement in your condition.
		Hydrochlorothiazide and amiloride should be taken at least 1 hour before or 4 hours after any dose of cholestyramine or colestipol.
	www.envisionrx.com /HTMLICONS/D03193A1.htm (1267 words)

	Contribution of amiloride-insensitive pathways to alveolar fluid clearance in adult rats -- Norlin et al. 90 (4): 1489 ...
		Addition of l-cis-diltiazem or amiloride to the instilled solution inhibited the stimulated alveolar fluid clearance to levels close to control.
		In the rat, 45% is amiloride sensitive; the amiloride-insensitive
		Amiloride inhibited 40-50% of alveolar fluid clearance under normal and stimulated conditions, an inhibition well in accordance
	jap.physiology.org /cgi/content/full/90/4/1489 (4826 words)

	Amiloride; Hydrochlorothiazide, HCTZ (Site not responding. Last check: 2007-10-29)
		AMILORIDE; HYDROCHLOROTHIAZIDE (Moduretic®) is a diuretic combination which is also known as a 'water pill'.
		Amiloride does not cause your body to lose potassium the way that many diuretics do.
		Amiloride; hydrochlorothiazide may make your skin more sensitive to sun or ultraviolet light.
	www.overlakehospital.staywellknowledgebase.com /26,863 (884 words)

	DETANONOate, a Nitric Oxide Donor, Decreases Amiloride-sensitive Alveolar Fluid Clearance in Rabbits -- NIELSEN et al. ...
		Current-voltage relationships of Xenopus oocytes were significantly decreased by 10 µM amiloride (panels A and B).
		AFC by (1) increasing the clearance of amiloride from the alveolar
		amiloride in saline, a fluid predicted to be rapidly cleared from
	ajrccm.atsjournals.org /cgi/content/full/161/4/1154 (4761 words)

	MedlinePlus Drug Information: Diuretics, Potassium-sparing (Systemic) (Site not responding. Last check: 2007-10-29)
		Amiloride and spironolactone are also used to treat high blood pressure (hypertension).
		Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
		Breast-feeding—Although amiloride, spironolactone, and triamterene may pass into breast milk, these medicines have not been reported to cause problems in nursing babies.
	www.nlm.nih.gov /medlineplus/druginfo/uspdi/202206.html (2443 words)

	Buy Moduretic (Amiloride and HCTZ) Online Without Prescription Needed
		The combination of amiloride and hydrochlorothiazide, a 'water pill,' is used to treat high blood pressure and fluid retention caused by various conditions, including heart disease.
		The combination of amiloride and hydrochlorothiazide comes as a tablet to take by mouth.
		Although side effects from amiloride and hydrochlorothiazide are not common, they can occur.
	www.1meds.com /Moduretic.html (657 words)

	Amiloride, Midamor
		Use of our encyclopedia will enable you to make well-informed, responsible decisions for the promotion of your own health and wellness.
		Diuretics increase urinary water loss from the body and are used to treat high blood pressure, congestive heart failure, and some kidney or liver conditions.
		This reduction of water in the body is the purpose of taking amiloride.
	www.truestarhealth.com /Notes/1311000.html (624 words)

	Biophysical properties and molecular characterization of amiloride-sensitive sodium channels in A549 cells -- Lazrak et ...
		Cells were then perfused with SES containing indicated concentrations of amiloride until a steady state was reached, usually within 3-5 min from onset of perfusion.
		Perfusion of cells with SES containing 10 µM forskolin induced a significant increase in inward current; >90% of forskolin-induced current was inhibited by amiloride.
		Effect of forskolin was totally abolished by presence of 10 µM amiloride in pipette (C).
	ajplung.physiology.org /cgi/content/full/278/4/L848 (6036 words)

	Self-Inhibition in Amiloride-sensitive Sodium Channels in Taste Receptor Cells -- Gilbertson and Zhang 111 (5): 667 -- ...
		Note ineffectiveness of amiloride (10 µM) in inhibiting currents in 35, 70, and 140 mM Na Currents were normalized to the current in 70 mM Na at
		The tight junction inhibitor, lanthanum chloride, and amiloride inhibited sodium-induced I
		In fungiform-containing epithelia, ~40% of the Na transport (mucosal, 500 mM; serosal, KH buffer) is inhibited by 0.5 mM amiloride
	www.jgp.org /cgi/content/full/111/5/667 (6304 words)

	Blood Pressure Responses to Small Doses of Amiloride and Spironolactone in Normotensive Subjects -- Pratt et al. 38 ...
		amiloride and spironolactone, and placebo were compared in normotensive
		Changes from baseline in systolic and diastolic BP during treatment with either placebo, amiloride, spironolactone, or the combination of amiloride and spironolactone.
		For the combination of amiloride and spironolactone, there was an overall decrease in mean systolic BP (P=0.022).
	hyper.ahajournals.org /cgi/content/full/38/5/1124 (2598 words)

	Antiidiotypic Antibody Recognizes an Amiloride Binding Domain within the alpha Subunit of the Epithelial Na+ Channel ...
		This antibody mimicked amiloride in that it inhibited
		of an anti-amiloride antibody with amiloride and consequent sequence
		We propose a model of amiloride binding to the Na channel based on the previous studies examining Na channel blockers and on the recent description of the tertiary
	www.jbc.org /cgi/content/full/274/14/9648 (5286 words)

	Amazon.com: Amiloride-Sensitive Sodium Channels: Physiology and Functional Diversity (Current Topics in Membranes): ... (Site not responding. Last check: 2007-10-29)
		SIPs: fetal distal lung epithelium, mucosal amiloride, fetal distal lung epithelial, terbutaline action, rat fetal distal (more)
		Epithelial ion channels permit the passage of ions and ultimately water across the epithelial barrier.
		Amiloride and Its Analogs : Unique Cation Transport Inhibitors by Edward J. Cragoe on page 378
	www.amazon.com /exec/obidos/tg/detail/-/0120890305?v=glance (615 words)

	Halothane Does Not Decrease Amiloride-Sensitive Alveolar Fluid Clearance in Rabbits -- Nielsen et al. 90 (6): 1445 -- ...
		with (n = 11) or without (n = 11) amiloride.
		absence of amiloride had similar AFC values (35% ± 12%
		Unlike the rat, the ability of the rabbit to clear fluid from
	www.anesthesia-analgesia.org /cgi/content/abstract/90/6/1445 (304 words)

	AMILORIDE - ORAL (Midamor) side effects, medical uses, and drug interactions. (Site not responding. Last check: 2007-10-29)
		AMILORIDE - ORAL (Midamor) side effects, medical uses, and drug interactions.
		MedicineNet Home > Medications A-Z List > amiloride-oral
		Please consult your healthcare provider before beginning any course of supplementation or treatment.
	www.medicinenet.com /amiloride-oral/article.htm (422 words)

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