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Topic: Aminorex

	MAPS - Volume 6 Number 2 Winter 1995-96 - 4-methyl aminorex (Site not responding. Last check: 2007-10-13)
		4-methyl aminorex produces a very long-lasting experience of about sixteen hours that is characterized by an increase in attention and an enhanced ability to recall, analyze and process information.
		What distinguishes 4-methyl aminorex from other substances like caffeine and nicotine, which also have these effects though to a lesser degree, is its effect on emotions.
		4-methyl aminorex may be the single most important drug for which research is not currently being attempted.
	www.maps.org /news-letters/v06n2/062144ia.html (258 words)

	Erowid Psychoactive Vault : DEA Federal Register
		Aminorex, also called aminoxaphen, 2-amino-5-phenyl-2-oxaoline, or 4,5-dihydro-5-phenyl-2-oxazolamine, is a phenethylamine in which the side chain has been cyclized into a substituted oxazoline.
		Aminorex is chemically and pharmacologically similar to amphetamine, methamphetamine, and cis-4-methylaminorex, all of which are controlled substances with high abuse potential.
		Any person who manufactures, distributes, delivers, imports or exports aminorex or who engages in research or conducts instructional activities with respect to aminorex, or who proposes to engage in such activities, must be registered to conduct such activity in accordance with parts 1301 and 1311 of title 21 of the Code of Federal Regulations.
	www.erowid.org /freedom/law/federal_register/59.FR.12828.shtml (1582 words)

	Erowid.org: Erowid Reference 1372 : Aminorex produces stimulus effects similar to amphetamine and unlike those of ...
		A 4-methyl derivative of aminorex has recently appeared on the clandestine market as a designer drug.
		In the present study, the stimulus effects of aminorex itself were evaluated in rats trained to discriminate either 0.75 mg/kg S(+)-amphetamine or 1.5 mg/kg fenfluramine from saline.
		Thus, the stimulus effects of aminorex are qualitatively similar to those of amphetamine and unlike those of fenfluramine.
	www.erowid.org /references/refs_view.php?ID=1372 (136 words)

	Dexfenfluramine (Site not responding. Last check: 2007-10-13)
		In the late 1960's, the widespread use of an appetite suppressant, aminorex, caused an epidemy of primary pulmonary hypertension, a deadly disease with no effective treatment available.
		Using the whole-cell patch clamp technique, we found that anorectics inhibit potassium channels in the cell membrane of the smooth muscle cells of resistance pulmonary arteries, causing membrane depolarization and vasoconstriction (Figure 1).
		This is a result of a patch-clamp experiment where the composition of the patch pipette solution and the bathing solution ensured that the current was carried exclusively by potassium.
	physiology.lf2.cuni.cz /hampl/vhdex.htm (340 words)

	Anorexic Agents Aminorex, Fenfluramine, and Dexfenfluramine Inhibit Potassium Current in Rat Pulmonary Vascular Smooth ... (Site not responding. Last check: 2007-10-13)
		In the isolated, perfused rat lung, aminorex, fenfluramine,
		Byrne-Quinn E, Grover R. Aminorex (Menocil) and amphetamine: acute and chronic effects on pulmonary and systemic haemodynamics in the calf.
		Aminorex, Fenfluramine, and Chlorphentermine Are Serotonin Transporter Substrates : Implications for Primary Pulmonary Hypertension
	circ.ahajournals.org /cgi/content/full/94/9/2216 (3626 words)

	FAQ (Site not responding. Last check: 2007-10-13)
		Over the next six years, an Aminorex related epidemic of primary pulomnary hypertension raged in Europe where a ten-fold increase in primary pulmonary hypertension cases is documented.
		Half of the PPH patients died within ten years and the rest suffered significant oxygen deprivation and are debilitated for the remainder of their lives.
		Pondimin is very similar to Aminorex and is in the same chemical family.
	www.dangelolaw.com /news.html (2323 words)

	CHEST: Recreational Use of Aminorex and Pulmonary Hypertension - ) (Site not responding. Last check: 2007-10-13)
		This drug was discovered on the property of three individuals with diagnoses of pulmonary hypertension.
		The association between "recreational" aminorex manufacture and ingestion and the development of pulmonary hypertension is described.
		We describe a cluster of patients with pulmonary hypertension that we believe was the result of "recreational" aminorex ingestion.
	www.findarticles.com /p/articles/mi_m0984/is_5_118/ai_67708361 (637 words)

	Primary Pulmonary Hypertension Resources (Site not responding. Last check: 2007-10-13)
		Between 1967 and 1973, an unexplained increase in the incidence of Primary Pulmonary Hypertension (PPH) was reported in central Europe.
		This increase was eventually attributed to aminorex fumarate, an amphetamine-like drug introduced in Europe in 1965 to control appetite.
		When aminorex was removed from the market, the incidence of PPH went down to normal levels.
	www.pph-info.com /pphlegalrights.html (371 words)

	Appearance of Aminorex as a Designer Analog of Methylaminorex
		A case in which aminorex (cis ± 4,5-dihydro-5-phenyl-2-oxazolamine) was prepared as a “designer” analog of a controlled substance, methylaminorex (cis ± 4,5-dihydro-4-methyl-5-phenyl-2-oxazolamine) is described.
		The confiscated drug sample was analyzed by high-field (300-mHz) proton nuclear magnetic resonance (NMR) and carbon-13 NMR spectroscopy, as well as electron impact mass spectrometry (70 eV).
		These examinations proved conclusively that the material in question was aminorex.
	www.astm.org /JOURNALS/FORENSIC/PAGES/1610.htm (123 words)

	Recreational Use of Aminorex and Pulmonary Hypertension -- Gaine et al. 118 (5): 1496 -- Chest
		Recreational Use of Aminorex and Pulmonary Hypertension -- Gaine et al.
		of the anorexic agent aminorex and subsided on removal of this
		use of an aminorex analog has not previously been described.
	www.chestjournal.org /cgi/content/full/118/5/1496 (689 words)

	Inter-Agency Committee on Drugs (IACD) (Site not responding. Last check: 2007-10-13)
		This paper considers the central nervous system stimulant aminorex - a drug that was used in the past as an appetite suppressant and has amphetamine-like effects.
		Aminorex is not controlled under the Misuse of Drugs Act 1975 (the Act).
		The Expert Advisory Committee on Drugs (EACD) recommends to the Minister of Health that aminorex be classified as a Third Schedule Part 5 controlled drug (Class C5).
	www.ndp.govt.nz /committees/eacd/papers.html (1015 words)

	AMINOREX
		Source: compiled by the editor from various references; see credits.
		Once aminorex was removed from the market, the incidence of PPH went down to normal levels.
		The rise was subsequently traced to aminorex fumarate, an amphetamine-like drug introduced in Europe in 1965 to control appetite.
	www.websters-online-dictionary.org /definition/AMINOREX (281 words)

	Appearance of Aminorex as a Designer Analog of Methylaminorex. Brewster ME, Davis FT . 1991;36(2): 587-592. (Site not responding. Last check: 2007-10-13)
		Appearance of Aminorex as a Designer Analog of Methylaminorex.
		Keywords: 4-methyl-aminorex, abuse drugs, aminorex, chemical analysis, designer drugs, forensic science, toxicology
		Abstract: A case in which aminorex (cis ± 4,5-dihydro-5-phenyl-2-oxazolamine) was prepared as a “designer” analog of a controlled substance, methylaminorex (cis ± 4,5-dihydro-4-methyl-5-phenyl-2-oxazolamine) is described.
	www.astm.org /jforensicsci/PAGES/1536.htm (99 words)

	Details of Aminorex (INN), brotizolam (INN), clotiazepam (INN), cloxazolam (INN), dextromoramide (INN), and other ... (Site not responding. Last check: 2007-10-13)
		Details of Aminorex (INN), brotizolam (INN), clotiazepam (INN), cloxazolam (INN), dextromoramide (INN), and other specified INNs; salts thereof tariff.
		Details of Aminorex (inn), Brotizolam (inn), Clotiazepam (inn), Cloxazolam (inn), Dextromoramide (inn), And Other Specified Inns; Salts Thereof
		Aminorex (inn), Brotizolam (inn), Clotiazepam (inn), Cloxazolam (inn), Dextromoramide (inn), And Other Specified Inns; Salts Thereof
	tariff.revisioncentral.co.uk /TariffDetails-29349100-A-8.aspx (886 words)

	AMINOREX (Site not responding. Last check: 2007-10-13)
		Aminorex ; Aminoxafen ; Aminoxaphen ; Menocil ;
		For more research articles and broader searching, click articles and information on AMINOREX.
		This site has been built on technology developed while creating a Memletics portal site.
	www.find-health-articles.com /DescD03.383.548.050-Aminorex.htm (147 words)

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