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Topic: Angioedema

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	NHS Direct - Health encyclopaedia -Angioedema
		Angioedema is a severe local swelling of the skin, particularly around the eyes, lips, nose, tongue, voicebox (larynx) or hands.
		Inherited angioedema is caused by a deficiency (not having enough) of a protein called the C1 inhibiting factor.
		An attack of genetic angioedema is treated with an injection of the C1 inhibitor, the substance that your body is deficient in.
	www.nhsdirect.nhs.uk /articles/article.aspx?printPage=1&articleId=25 (1322 words)

	eMedicine - Angioedema : Article by Maurice Reid
		Angioedema is characterized by painless, nonpruritic, nonpitting, and well-circumscribed areas of edema due to increased vascular permeability.
		Angioedema related to reactions mediated by immunoglobulin E is discussed in Anaphylaxis.
		Angioedema of the submucosal and subcutaneous tissue is tense, nonpitting, nonpruritic, and nonerythematous.
	www.emedicine.com /med/topic135.htm (4357 words)

	URTICARIA (HIVES) AND ANGIOEDEMA
		Urticaria (hives) and angioedema (swelling of deep skin tissues) are common skin problems which affect approximately 20% of Americans at some time in their lives.
		Angioedema can appear as swelling of the eyelids, lips, facial area, throat, hands/fingers, genitals, or feet/toes with no obvious overlying skin rash.
		Angioedema is typically tingling and burning in sensation, rather than itchy.
	www.asthmacenter.com /allergy/urticaria.html (570 words)

	eMedicine - Angioedema : Article by Nedra Dodds, MD (Site not responding. Last check: 2007-10-13)
		Urticaria is localized to the superficial portion of the dermis and is characterized by well-circumscribed wheals with raised erythematous borders and central blanching.
		It is characterized by fever, angioedema, arthralgias, urticaria, and palpable purpura.
		Hereditary angioedema is characterized by low levels of C1 esterase inhibitor (C1INH) or elevated levels of dysfunctional C1 esterase inhibitor, as detected by an immune assay.
	www.emedicine.com /emerg/topic32.htm (2261 words)

	[No title]
		Angioedema has been associated with a variety of diseases, including hereditary and acquired C1-esterase inhibitor deficiency, drugs, and foods, or angioedema may be idiopathic [4, 5].
		Hereditary angioedema is an autosomaldominant condition with an estimated prevalence of from one case per 50,000 to one case per 150,000 persons [6, 7].
		Angioedema may be limited to the gastrointestinal tract, but concomitance of cutaneous and respiratory involvement is a frequent finding [4, 5].
	www.lycos.com /info/angioedema.html (656 words)

	Angioedema - Health Encyclopedia
		Angioedema is a swelling similar to urticaria (hives), but the swelling is beneath the skin rather than on the surface.
		Angioedema is usually the result of an allergic (hypersensitivity) reaction.
		Angioedema that does not affect the breathing may be uncomfortable, but is usually harmless?and goes away?in a few days.
	www.nbc11.com /encyclopedia/6865466/detail.html (643 words)

	UCLA Department of Medicine - wfsection-Hereditary Angioedema
		Hereditary angioedema is a disease characterized by episodic bouts of subcutaneous or submucosal swelling involving the face, limbs, and soft tissues.
		Type I hereditary angioedema is characterized by an absolute deficiency of C1 inhibitor, and type II is characterized by normal or high levels of a functionally defective C1 inhibitor.
		The diagnosis of hereditary angioedema should be considered in patients who present with a history of clinical manifestations and a family history of the disease.
	www.med.ucla.edu /modules/wfsection/article.php?articleid=110 (1987 words)

	Urticaria (Hives) and Angioedema
		Angioedema is tissue swelling similar to urticaria, but the swelling occurs beneath the skin instead of on the surface.
		Angioedema is characterized by deep swelling around the eyes and lips and sometimes of the genitals, hands and feet.
		For severe hive or angioedema outbreaks, an injection of epinephrine (adrenaline) or a cortisone medication may be needed.
	www.clevelandclinic.org /health/health-info/docs/1900/1960.asp?index=8630 (817 words)

	Angioedema
		Thomas A. Salzer, M.D. Angioedema is a problem that relates to the specialty of otolaryngology because its symptoms manifest most often in the head and neck, often in dramatic form.
		The term angioedema is used to describe several closely related diseases that manifest by recurrent acute edema of the skin and mucosa.
		Angioedema is characterized by subcutaneous edema resulting from increased vascular permeability, dilation of venules and capillaries and separation of collagen bundles.
	www.bcm.edu /oto/grand/52694.html (1202 words)

	Auckland Allergy Clinic - Urticaria and Angioedema
		Angioedema is associated with urticaria in about 40% of cases or occurs on its own in 10% of cases.
		Angioedema occurs with CU in 50% of cases and Delayed pressure urticaria in about 40%.
		Angioedema may affect the oropharynx but is not life threatening.
	www.allergyclinic.co.nz /guides/32.html (1235 words)

	Hereditary Angioedema - Health Encyclopedia
		Hereditary angioedema is a rare but serious problem with the immune system that is passed down through families.
		Hereditary angioedema (HAE) is caused by low levels or improper function of a protein called C1 inhibitor.
		Self-administration of C1-inhibitor concentrate in patients with hereditary or acquired angioedema caused by C1-inhibitor deficiency.
	www.nbc4.tv /encyclopedia/6862026/detail.html (675 words)

	PalmBeachPost Health : Integrative Medicine : Conditions : Angioedema
		An angioedema reaction (AAE in particular) may be caused by allergies to foods, dyes, or pollen, or in reaction to certain medications, including nonsteroidal anti-inflammatory drugs (NSAIDs, such as ibuprofen) and angiotensin-converting enzyme (ACE) inhibitors (such as captopril, lisinopril, enalapril).
		Apis is traditionally used for hives and angioedema and may be useful to prevent or treat chronic, recurrent cases.
		It is also possible that the angioedema may develop into anaphylaxis, which will require emergency medical care to maintain breathing, blood pressure, and heart function and to reverse the reaction.
	www.palmbeachpost.com /health/altmed/shared/health/alt_medicine/ConsConditions/Angioedemacc.html (1021 words)

	Angioedema of the Head and Neck
		Angioedema is a sudden onset of a localized nonpitting edema involving the deeper layers of the skin and submucosal tissue, most commonly affecting the lips and face, extremities, and abdominal viscera.
		Acquired angioedema is due to an acquired deficiency in circulating levels of C1 inhibitor.
		One study showed the causes of angioedema as: 50% were idiopathic, 33% were ACE inhibitor induced, and the remainder were caused by allergy and hereditary.
	www.bcm.edu /oto/grand/12_22_05.htm (3206 words)

	Angioedema, Unusual Presentations
		Two cases of hereditary angioedema and one of acquired angioedema are reported because of their unusual emergency department presentations.
		The diagnosis is usually established by a family history of angioedema in a symptomatic patient, and the diagnosis is confirmed by biochemical C 1 esterase inhibitor deficiency or functional deficiency.
		Acquired forms of angioedema are associated with an underlying hematologic malignancy or immune complex disease, resulting in activation of C1Q in the complement cascade.
	www.ccspublishing.com /journals/derm/angioede.htm (1625 words)

	Urticaria (Hives) & Angioedema (Swelling of the Face) in Dogs
		Urticaria and angioedema are hypersensitivity (or allergic) reactions to drugs, chemicals, something eaten, or even sunlight.
		Angioedema and urticaria generally develop within 20 minutes of being exposed to the allergen (substance to which the animal is allergic).
		If a pet has already had a reaction, such as anaphylaxis, angioedema, or hives, to a substance, the substance should be avoided.
	www.peteducation.com /article.cfm?cls=2&cat=1707&articleid=1494 (416 words)

	Allergic Diseases Resource Center: Urticaria and Angioedema
		Angioedema (in the past this was called giant urticaria or angioneurotic edema) is a condition involving swelling in the deeper layers of the skin, caused by a build up of fluid leaking from thin-walled blood vessels.
		Urticaria and angioedema can be symptoms of a systemic reaction called anaphylaxis and may require urgent administration of intramuscular epinephrine (adrenaline).
		Urticaria and angioedema are thought to affect 20% of the population at some time during their lifetime.
	www.worldallergy.org /public/allergic_diseases_center/urticaria/urticaria.shtml (1793 words)

	Angioedema (Site not responding. Last check: 2007-10-13)
		There seems to be a hereditary tendency toward the development of both angioedema and hives (see hereditary angioedema).
		Angioedema is associated with the release of histamine and other chemicals into the bloodstream, which is part of the allergic response.
		To prevent recurrence of angioedema avoid irritating the affected area, avoid known allergens, and avoid temperature extremes.
	www.nioeyes.com /eyes/problems/Angioedema.htm (500 words)

	Hives and Angioedema: Allergic Reactions: Merck Manual Home Edition
		Angioedema is swelling of larger areas of tissue under the skin, sometimes affecting the face and throat.
		Hereditary angioedema is a genetic disorder due to a deficiency or malfunction of C1 inhibitor.
		For example, before a dental or surgical procedure, people with hereditary angioedema may be given a transfusion of fresh plasma to increase levels of C1 inhibitor in the blood.
	www.merck.com /mmhe/sec16/ch185/ch185h.html (825 words)

	Edema
		The differamce is that angioedema involves vessels in the layers of the indodermal regions whereas uticaria is localized superficial to the dermis.
		The diagnosis on angioedema is generally done of the basis of the appearance of the skin and observation of the expression of symptoms.
		Hereditary Angioedema is a rare inherited disorder characterized by an accumulation of fluids outside of the blood vessels, blocking the normal flow of blood or lymphatic fluid and causing rapid swelling of tissues in the hands, feet, limbs, face, intestinal tract, or airway.
	www.lymphedemapeople.com /thesite/edema_angioedema.htm (3452 words)

	Postgraduate Medicine: URTICARIA AND ANGIOEDEMA - Controlling acute episodes, coping with chronic cases.
		Laryngeal swelling is rare when angioedema is associated with urticaria, but it can occur with C1 inhibitor deficiency, angioedema caused by use of angiotensin-converting enzyme (ACE) inhibitors, or anaphylaxis.(3,4) Angioedema without urticaria occurs in a small percentage of patients and may be associated with an underlying complement disorder or ACE inhibitor use.
		The incidence of angioedema induced by ACE inhibitors is reported as 1 to 4 per 1,000 patients and is higher among African Americans(9).
		Management of angioedema is more difficult than that of urticaria because angioedema tends to take its own time to resolve, regardless of what treatment is initiated.
	www.postgradmed.com /issues/2005/05_05/varadarajulu.htm (2913 words)

	Picture of Angioedema * Otolaryngology Houston
		Angioedema is most apparent in the head and neck, including the
		Angioedema may involve the gastrointestinal tract, leading to intestinal wall edema, which results in symptoms such as colicky abdominal pain, nausea, vomiting, and diarrhea.
		Hereditary Angioedema (HAE) is a rare and serious genetic condition occurring in about 1/10,000 to 1/50,000 individuals.
	www.ghorayeb.com /Angioedema.html (175 words)

	Angioedema (Site not responding. Last check: 2007-10-13)
		Angioedema is a reaction characterized by fluid accumulation leading to swelling (oedema) of the skin, mucosa and submucosal tissues.
		As for acquired angioedema, it is presumed to affect all races where both males and females are affected equally.
		The diagnosis of angioedema is based on the signs and symptoms of the patient, and the history of exposure to allergens, and therefore does not rely on laboratory testing.
	www.virtualrespiratorycentre.com /diseases.asp?did=760 (634 words)

	Dyax: Hereditary Angioedema (HAE)
		Hereditary angioedema is rare, affecting an estimated 1 in 10,000 to 1 in 50,000 people in the US and worldwide.
		The US Hereditary Angioedema Association, run by patients and their families, offers helpful information and a chance to talk to others dealing with HAE.
		Hereditary angioedema (HAE) is an acute inflammatory condition characterized by episodes of severe, often painful swelling affecting the extremities (hands, feet, face, etc.), the gastrointestinal tract, the genitalia, and in life-threatening cases, the larynx.
	www.dyax.com /clinical/hereditaryang.html (1245 words)

	Hives Allergy (Urticaria)
		Angioedema is similar to urticaria, but the swelling occurs beneath the skin instead of on the surface.
		Hives and angioedema form when, in response to histamine, blood plasma leaks out of small blood vessels in the skin.
		For severe hive or angioedema outbreaks, an injection of epinephrine or a steroid medication may be needed.
	www.webmd.com /content/pages/10/1625_50521.htm (747 words)

	Urticaria and Angioedema
		Urticaria and angioedema are thought to affect 25% of the population at some time.
		Angioedema is similar to urticaria, but it involves slightly deeper-seated tissues.
		Swelling of deeper layers of the skin, angioedema, is often seen with hives.
	home.clara.net /radcliffe/urticariaandangioedema.htm (377 words)

	Hives and angioedema - MayoClinic.com
		Angioedema, a similar swelling, causes large welts deeper in your skin, especially near your eyes and lips.
		A more serious condition — hereditary angioedema (HAE) — is an uncommon, inherited disorder, which can cause sudden, severe and rapid swelling of your face, arms, legs, hands, feet, genitalia, digestive tract and airway.
		Serious angioedema can be life-threatening if swelling causes your throat or tongue to block your airway and leads to loss of consciousness.
	www.mayoclinic.com /health/hives-and-angioedema/DS00313 (240 words)

	Chronic Angioedema
		In many cases, chronic angioedema is not present the whole time, what is happening is that the patient is really getting recurring attacks of acute angioedema.
		Angioedema, urticaria (hives), anaphylaxis and asthma all become more likely if one of these drugs is being taken.
		Inherited angioedema responds to treatments that are quite a bit different from the other forms of angioedema.
	home.clara.net /radcliffe/angioedema_chronic.htm (1159 words)

	angioedema (Site not responding. Last check: 2007-10-13)
		Angioedema is a potentially dangerous condition involving sudden swelling of the superficial tissues of the body.
		It is triggered by the immune system in response to allergens including foods, medicines, insect bites or stings, infections, and sometimes to trauma to the body area.
		The most common areas of the body involved in angioedema are the facial and genital regions.
	www.drhull.com /EncyMaster/A/angioedema.html (174 words)

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