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Topic: Anoxia


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 Brain Anoxia or Hypoxia
Specifically, anoxia is a condition in which there is an absence of oxygen supply to an organ's tissues although there is adequate blood flow to the tissue.
Anoxia and hypoxia, however, are often used interchangeably -- without regard to their specific meanings -- to describe a condition that occurs in an organ when there is a diminished supply of oxygen to the organ's tissues.
Anoxia and hypoxia may be caused by a number of events, such as smoke or carbon monoxide inhalation, high altitude exposure, strangulation, anesthetic accidents, or poisoning.
healthlink.mcw.edu /article/921384224.html   (303 words)

  
 Anoxia
Anoxia is a condition characterized by an absence of oxygen supply to an organ or a tissue.
Affinity anoxia involves a defect in the chemistry of the blood such that the hemoglobin can no longer pick up as much oxygen from the air, even though the quantities are normal, reducing how much is delivered to the tissues.
However, some forms of anoxia do not increase lactic acid concentrations in the blood and some increases in lactic acid levels are not associated with anoxia, so an elevated value for this test is only suggestive of an anoxic or hypoxic condition.
www.healthatoz.com /healthatoz/Atoz/ency/anoxia.jsp   (1206 words)

  
 Anoxia/Hypoxia
DESCRIPTION: Specifically, anoxia is a condition in which there is an absence of oxygen supply to an organ's tissues although there is adequate blood flow to the tissue.
Anoxia and hypoxia, however, are often used interchangeably--without regard to their specific meanings--to describe a condition that occurs in an organ when there is a diminished supply of oxygen to the organ's tissues.
TREATMENT: Treatment of anoxia and hypoxia consists of establishing an adequate airway as soon as possible, using enough oxygen to saturate the blood, supporting the cardiovascular system as needed, and preventing or treating pneumonia.
www.neuroskills.com /tbi/anoxia.shtml   (344 words)

  
 Introduction: Anoxia - WrongDiagnosis.com
Anoxia: Specifically, anoxia is a condition in which there is an absence of oxygen supply to an organ's tissues although there is adequate blood flow to the tissue.
Anoxia and hypoxia, however, are often used interchangeably—without regard to their specific meanings—to describe a condition that occurs in an organ when there is a diminished supply of oxygen to the organ's tissues.
Researching symptoms of Anoxia: Further information about the symptoms of Anoxia is available including a list of symptoms of Anoxia, or alternatively return to research other symptoms in the symptom center.
www.wrongdiagnosis.com /a/anoxia/intro.htm   (255 words)

  
 Brain Damage from Anoxia   (Site not responding. Last check: 2007-10-09)
Anoxia is known as a lack of oxygen to the brain.
Anoxia can also occur as a result of chronic asthma, a heart attack, or the inhalation of carbon monoxide or smoke, according to the National Institute of Neurological Disorders and Stroke.
I had never heard of anoxia until I did some research on brain injury, and saw that it was impo...
www.suite101.com /article.cfm/7507/45430   (574 words)

  
 Glycolysis Prevents Anoxia-Induced Synaptic Transmission Damage in Rat Hippocampal Slices -- Tian and Baker 83 (4): ...
Recordings were obtained before anoxia, at the end of 60 min anoxia (A) or 120 min anoxia (C), and at the end of 60 min reoxygenation in A and C.
Persistence of PV and fEPSP or the fEPSP reappearance during anoxia indicates that the synaptic transmission is partially maintained, and the glycolysis of glucose partially supported the synaptic transmission during such prolonged up to 120 min anoxia at 20 mM glucose in ACSF.
Recordings were obtained before anoxia, at the end of 120 min combined anoxia (A) or 10 min chemic anoxia alone (C) and at the end of 60 min reoxygenation in A and C.
jn.physiology.org /cgi/content/full/83/4/1830   (6316 words)

  
 Novel Injury Mechanism in Anoxia and Trauma of Spinal Cord White Matter: Glutamate Release via Reverse Na+-dependent ...
Slices were exposed to 60 min of anoxia, and compound action potentials were measured at 60 and 120 min of reoxygenation (60' and 120' post-anoxia bars).
Anoxia or trauma causes disturbances of ionic gradients
Central myelinated axons are susceptible to a variety of insults, the commonest being anoxia and ischemia, trauma, and demyelination.
www.jneurosci.org /cgi/content/full/19/14/RC16   (4695 words)

  
 Dephosphorylation of Cell Cycle-regulated Proteins Correlates with Anoxia-induced Suspended Animation in Caenorhabditis ...
Survival of nematodes in anoxia for 24 h (white bars), 48 h (slashed bars), or 72 h (fl bars) was determined for all stages of development.
anoxia, we assayed the ratio of adenine nucleotides.
Experimental embryos (anoxia) remained in the anoxic environment for 24 h and were either immediately collected or allowed to recover in air for 1 h (postanoxia).
www.molbiolcell.org /cgi/content/full/13/5/1473   (5667 words)

  
 [No title]   (Site not responding. Last check: 2007-10-09)
Anoxia exposure also led to qualitative changes in the protein products that resulted from in vitro translation.
Anoxia stimulated the appearance of a 37.5 kDa protein in red skeletal muscle but anoxic red muscle also lost proteins of 40, 32, and 28.2 kDa that were present in aerobic controls.
Anoxia exposure did not change the proteins produced by in vitro translation in white muscle.
www.carleton.ca /~kbstorey/dnd1.htm   (372 words)

  
 eSynopsis of Anoxia of the Brain
•Anoxia is due to lack of oxygen transport to the brain
•Anoxia interferes with the function of neurons causing swelling of mitochondria due to loss of their ability to process glucose and lack of energy production for the use of other organelles and membranes in the cells.
•Anoxia is comman in patients exposed to CO in fires and patients who develop a cardiopulmonary arrest, particularly out of the hospital when CPR is not begun within 4 minutes.
esynopsis.uchc.edu /S456.htm   (253 words)

  
 Olga Blokhina: Anoxia and Oxidative Sterss: Lipid Peroxidation, Antioxidant Status and Mitochondrial Functions in Plants
Incubation of the anoxia intolerant plant tissues under oxygen deprivation caused changes in the cell ultrastructure such as plasmolysis and disintegration of organelles.
Superimposed factors such as the duration of the anoxic treatment and the reoxygenation period are significant for the estimation of the defense efficiency, and hence anoxia tolerance.
During the time course of anoxia increased LP, measured as CD, CT and TBARS formation, resulted in a significant decrease of both reduced and oxidised forms of ascorbic acid and glutathione, despite the differences in the initial antioxidant content.
ethesis.helsinki.fi /julkaisut/mat/bioti/vk/blokhina/ch4.html   (4939 words)

  
 [No title]   (Site not responding. Last check: 2007-10-09)
Tissue-specific controls on carbohydrate metabolism regulate the response to anoxia in goldfish (Carassius auratus) and bring about the overall metabolic rate depression that is a key feature of anoxia tolerance.
The effect of anoxia (24 h at 7oC under N2/ CO atmosphere) on glycogen phosphorylase activity and on the content of fructose-2,6-bisphosphate was determined in eight tissues (liver, brain, kidney, gill, spleen, heart, and red and white skeletal muscle) of goldfish.
Anoxia resulted in an increase in the percentage of phosphorylase in the active a form in brain but significantly reduced phosphorylase-a content in liver, kidney, spleen, and heart; total phosphorylase activity (a + b) was also reduced during anoxia in liver and gill.
www.carleton.ca /~kbstorey/kbs37.htm   (226 words)

  
 Expression of heat shock proteins in turtle and mammal hearts: relationship to anoxia tolerance -- Chang et al. 278 ...
12 h of anoxia or 12 or 24 h of recovery.
the ability of turtles to withstand anoxia is impressive (15).
Anoxia induces changes in translatable mRNA populations in turtle organs: a possible adaptive strategy for anaerobiosis.
ajpregu.physiology.org /cgi/content/full/278/1/R209   (3750 words)

  
 IMPORTANCE OF SEED CARBOHYDRATES IN RICE SEEDLING ESTABLISHMENT UNDER ANOXIA
The importance of carbohydrates in rice seeds exposed to anoxia was evaluated in two rice cultivars differing in anoxia tolerance.
Glucose feeding during anoxia of half seeds increased survival and plant height and demonstrated that reduced survival was largely the result of low carbohydrate supply and not of seed wounding.
The better growth under anoxia in larger seeds, in more dense seeds, and in half seeds supplied with glucose supports the importance of seed carbohydrates in seedling establishment under anoxia.
www.actahort.org /books/504/504_22.htm   (293 words)

  
 Multiple Sclerosis: Anoxia And Ischemic Injury Of Myelinated Axons In CNS White Matter
Anoxia and Ischemia cause rapid energy depletion, failure of the Na -ATPase, and accumulation of AxoPlasmic Na through noninactivating Na channels, with concentrations approaching 100 mmol/L after 60 minutes of Anoxia.
Although Glia are relatively resistant to Anoxia, Oligodendrocytes and the Myelin sheath may be damaged by Glutamate released by reverse Na -Glutamate transport.
In Optic Nerves exposed to TTX studied at the end of a 60-min period of Anoxia, Mitochondria showed swelling and loss of Cristae, and terminal Oligodendroglial loops were detached from the Nodal Axon membrane.
thjuland.net /anoxia.html   (2613 words)

  
 Oxygen deprivation causes suspended animation in the zebrafish embryo -- Padilla and Roth 98 (13): 7331 -- Proceedings ...
survive in the absence of molecular oxygen (anoxia) (8-11).
Several invertebrates that survive anoxia are only able to do so at specific times in development (11, 12).
Embryos exposed to anoxia for 19 h were allowed to recover in air, and heart rate of these recovering embryos was determined.
www.pnas.org /cgi/content/full/98/13/7331   (2937 words)

  
 Anoxic induction of ATF-4 through HIF-1-independent pathways of protein stabilization in human cancer cells -- Ameri et ...
by anoxia was rapidly degraded in normoxia, normoxic and hypoxic
ATF-4 expression in hypoxia and anoxia and correlation with
Cells were incubated for 24 hours in normoxic conditions, after which they were placed in anoxia for 16 hours or left in normoxia for 16 hours.
www.bloodjournal.org /cgi/content/full/103/5/1876   (5004 words)

  
 Negotiating brain anoxia survival in the turtle -- Lutz and Milton 207 (18): 3141 -- Journal of Experimental Biology
A diagrammatic overview of some of the factors involved in negotiating anoxia survival in the turtle brain.
Constitutive factors that predispose for anoxia tolerance include enhanced levels of glycogen stores, elevated heat shock protein, increased densities of protective receptors and elevated antioxidant capacities.
Three distinct phases are involved in surviving and recovering from anoxia.
jeb.biologists.org /cgi/content/full/207/18/3141   (4155 words)

  
 Role of Na+/H+ exchanger during O2 deprivation in mouse CA1 neurons -- Yao et al. 281 (4): C1205 -- AJP - Cell ...
change in response to anoxia, a smaller increase was seen in the mutant neuron.
Anoxia induces an increase in intracellular sodium in rat central neurons in vitro.
and Na homeostasis during anoxia in rat hypoglossal neurons: intracellular and extracellular in vitro studies.
ajpcell.physiology.org /cgi/content/full/281/4/C1205   (3779 words)

  
 The Cause(s) of Continued Hypolimnetic Anoxia in Long Lake, Washington, Following Advances Wastewater Treatment by the ...   (Site not responding. Last check: 2007-10-09)
The purpose of this study was to determine the cause(s) of continued hypolimnetic anoxia in Long Lake with advanced wastewater treatment in operation.
The purpose of this study was to determine the cause(s) of continued hypolimnetic anoxia in Long Lake with AWT in operation.
The phytoplankton standing crop in Long Lake does affect oxygen demand both within the water column and at the sediment-water interface, and is a primary factor in the seasonal decline of dissolved oxygen levels in Long Lake.
www.ecy.wa.gov /biblio/8231.html   (421 words)

  
 glycolysis prevents anoxia damage   (Site not responding. Last check: 2007-10-09)
We tested the hypothesis that lack of glucose is the major cause of irreversible anoxic transmission damage, and that anoxic synaptic transmission damage could be prevented by glycolysis in rat hippocampal slices.
The evoked population spike (PS) was extracellularly recorded in the CA1 pyramidal cell layer after stimulation of the Schaffer collaterals.
We conclude that lack of glucose is the major cause of anoxia-induced synaptic transmission damage, and that if sufficient glucose is supplied, glycolysis could prevent this damage in vitro.
www.cryonet.org /cgi-bin/dsp.cgi?msg=14441   (316 words)

  
 Sugar Modulation of {alpha}-Amylase Genes under Anoxia -- LORETI et al. 91 (2): 143 -- Annals of Botany
Effects of anoxia, gibberellic acid and glucose on Ramy1A and Ramy3D mRNA accumulation in embryoless half-grains.
anoxia is the consequence of the anoxia-induced altered sugar
Effect of anoxia on carbohydrate metabolism in rice seedlings.
aob.oxfordjournals.org /cgi/content/full/91/2/143   (2964 words)

  
 glucose and hippocampal anoxia   (Site not responding. Last check: 2007-10-09)
X-Message-Number: 14988 From: Date: Tue, 21 Nov 2000 21:43:49 EST Subject: glucose and hippocampal anoxia Following is an edited and abridged version of an interesting abstract: J Neurophysiol 83: 1830-1839.
When the slice was superfused with artificial cerebrospinal fluid (ACSF) containing 4 mM glucose, following 10 min anoxia, the evoked PS [population spike] did not recover at all after 60 min reoxygenation.
We conclude that lack of glucose is the major cause of anoxia-induced synaptic transmission damage.
www.cryonet.org /cgi-bin/dsp.cgi?msg=14988   (273 words)

  
 Antioxidants, Oxidative Damage and Oxygen Deprivation Stress: a Review -- BLOKHINA et al. 91 (2): 179 -- Annals of ...
anoxia and reoxygenation was not accompanied with concurrent
Patterns of protein synthesis and tolerance of anoxia in root tips of maize seedlings acclimated to a low-oxygen environment, and identification of proteins by mass spectrometry.
Enrichment and functional reconstitution of glutathione transport activity from rabbit kidney mitochondria: further evidence for the role of dicarboxylate and 2-oxoglutarate carriers in mitochondrial glutathione transport.
aob.oxfordjournals.org /cgi/content/full/91/2/179   (7186 words)

  
 Anoxia-reoxygenation versus ischemia in isolated rat lungs -- Zhao et al. 273 (6): 1112 -- AJP - Lung Cellular and ...
A basic question is whether anoxia with reoxygenation, as distinct from ischemia-reperfusion, results in lung oxidant generation
, 1 h of anoxia followed by 1 h of reoxygenation; I, 1 h of ischemia with continued ventilation; I/R, 1 h of ischemia followed by 1 h of reperfusion.
In the present study, the expected decrease in lung ATP content with anoxia was observed.
ajplung.physiology.org /cgi/content/full/273/6/L1112   (3570 words)

  
 Resistance of isolated pulmonary mitochondria during in vitro anoxia/reoxygenation.   (Site not responding. Last check: 2007-10-09)
Mitochondrial respiratory parameters were determined in isolated mitochondria before anoxia (control), after 5-45 min anoxia followed by 5 min reoxygenation, and after 25 or 40 min of in vitro incubation in order to follow the in vitro aging of mitochondria during respiratory assays.
Respiratory parameters measured after anoxia/reoxygenation did not show any oxidative phosphorylation dysfunction, indicating a high resistance of pulmonary mitochondria to in vitro anoxia/reoxygenation (up to 45 min anoxia).
These results indicate that mitochondria are not directly responsible of their oxidative phosphorylation damage observed after in vivo ischemia (K. Willet et al., Transplantation 69 (2000) 582) but are a target of others cellular injuries leading to mitochondrial dysfunction in vivo.
www.arclab.org /medlineupdates/abstract_11106775.html   (174 words)

  
 Hypoxia-Induced Silencing of NMDA Receptors in Turtle Neurons -- Bickler et al. 20 (10): 3522 -- Journal of Neuroscience
During the first few minutes of anoxia, the turtle NMDAR is inactivated by a mechanism involving phosphatase 1 or 2A.
Dephosphorylation of NMDARs by phosphatases early in anoxia may be related to later changes in NMDAR expression or distribution.
Bickler PE (1998) Reduction of NMDA receptor activity in cerebrocortex of turtles (Chrysemys picta) during 6 wk of anoxia.
www.jneurosci.org /cgi/content/full/20/10/3522   (4068 words)

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