
	Where results make sense

Topic: Anticonvulsant

In the News (Sun 27 May 12)

EXECUTIVE POWER

Iran

ANALYSIS

Pakistan

Family compact

	Anticonvulsant - Wikipedia, the free encyclopedia
		The anticonvulsants, sometimes also called antiepileptics, belong to a diverse group of pharmaceuticals used in prevention of the occurrence of epileptic seizures.
		The goal of an anticonvulsant is to suppress the rapid and excessive firing of neurons that start a seizure.
		Failing this, a good anticonvulsant would prevent the spread of the seizure within the brain and offer protection against possible excitotoxic effects that may result in brain damage.
	en.wikipedia.org /wiki/Anticonvulsant (576 words)

	Anticonvulsant Drugs Information on Healthline
		Anticonvulsant drugs are medicines used to prevent or treat convulsions (seizures).
		Anticonvulsant drugs act on the brain to reduce the frequency and severity of seizures.
		Because anticonvulsant drugs work on the central nervous system, they may add to the effects of alcohol and other drugs that slow down the central nervous system, such as antihistamines, cold medicine, allergy medicine, sleep aids, other medicine for seizures, tranquilizers, some pain relievers, and muscle relaxants.
	www.healthline.com /galecontent/anticonvulsant-drugs (1161 words)

	Anticonvulsants
		Anticonvulsants are a family of drugs that depress abnormal nerve activity in the brain, thereby blocking seizures.
		One study revealed that individuals on long-term anticonvulsant therapy, despite having no laboratory signs of anemia, had dramatically lower levels of vitamin B12 in their cerebrospinal fluid (the fluid that bathes the brain) when compared with people who were not taking seizure medications.
		In a controlled study, bone strength improved in children taking anticonvulsant drugs who were supplemented with the activated form of vitamin D and 500 mg per day of calcium for nine months.
	www.gianteagle.com /healthnotes/Drug/Anticonvulsants.htm (2277 words)

	Anticonvulsant Induced Rickets - Bibliography - Orthopaedic Rare Conditions Internet Database (Site not responding. Last check: 2007-10-06)
		Vitamin D metabolism and anticonvulsant therapy: effect of sunshine on incidence of osteomalacia.
		Vitamin D prophylaxis and the lowered incidence of fractures in anticonvulsant rickets and osteomalacia.
		Rickets associated with long-term anticonvulsant therapy in a pediatric outpatient population.
	condor.sechrest.com /ortho/orcid/rickbib.htm (713 words)

	Convulsion Drugs \| myhealth@wellmark (Site not responding. Last check: 2007-10-06)
		Anyone who has had unusual reactions to anticonvulsant drugs or to tricyclic antidepressants such as imipramine (Tofranil) or desipramine (Norpramin) in the past should let his or her physician know before taking the drugs again.
		Some anticonvulsant drugs should not be taken within two to three hours of taking antacids or medicine for diarrhea.
		Anyone who takes anticonvulsant drugs should let the physician know all other medicines he or she is taking.
	www.myhealthwellmark.com /topic/convulsiondrugs (1911 words)

	Side effects of anticonvulsant medications
		Anticonvulsant medications such as barbiturates, phenytoin, carbamazapine, primidone, and valporic acid are known to deplete vital nutrients.
		Anticonvulsant therapy seems to have a negative influence on plasma levels of vitamin C (Singh).
		Epileptics on anticonvulsant medications may have reduced plasma alpha tocopherol (Vitamin E) levels and this may be due in part to the use of anticonvulsants.
	www.learningdiscoveries.org /SideEffectsofAnticonvulsantMedications.htm (3372 words)

	Anticonvulsant drugs for migraine prophylaxis
		The authors conclude that anticonvulsant drugs are indeed effective in reducing the frequency of migraine attacks by approximately 1-2 attacks per month.
		Anticonvulsant drugs seem to be useful in clinical practice for the prophylaxis of migraine.
		Of these, 14 reported trials comparing anticonvulsants with placebo, as follows: four trials of divalproex sodium, three trials of topiramate, two trials of sodium valproate, two trials of gabapentin, and one trial each of carbamazepine, clonazepam, and lamotrigine.
	www.cochrane.org /reviews/en/ab003226.html (681 words)

	EAGO Newsletter (Site not responding. Last check: 2007-10-06)
		Not only does the necessity for anticonvulsant therapy need to be reconsidered, but the woman ought to be on a single anticonvulsant agent and on the lowest possible dose which will control her seizures.
		All the major anticonvulsant drugs (carbamazepine, sodium valproate, phenytoin, phenobarbitone and mysoline) are teratogenic but the main risk to the developing fetus appears to be when the mother is on polytherapy, especially if sodium valproate forms part of the combination.
		During pregnancy total anticonvulsant concentrations fall because there is an increase in circulating blood volume and an alteration in fluid distribution and metabolism, though free anticonvulsant concentrations remain unchanged or even increase.
	www.obgyn.net /eago/art08.htm (1497 words)

	Anticonvulsants
		Individuals on long-term multiple anticonvulsant therapy may develop below-normal blood levels of calcium, which may be related to drug-induced vitamin D deficiency.
		Several studies have shown that multiple anticonvulsant therapy reduces blood levels of folic acid and dramatically increases homocysteine levels.
		One preliminary study showed that pregnant women who use anticonvulsant drugs without folic acid supplementation have an increased risk of having a child with birth defects, such as heart defects, cleft lip and palate, neural tube defects, and skeletal abnormalities.
	www.evitamins.com /healthnotes.asp?ContentID=1082009 (1760 words)

	Parkinsn's List Drug DataBase phenytoin / Dilantin
		Phenytoin exerts its anticonvulsant effect mainly by limiting the spread of seizure activity and reducing seizure propagation, unlike phenobarbital and carbamazepine, which elevate the seizure threshold.
		Phenytoin's anticonvulsant effects are mediated through effects on sodium channels on the neuronal cell membrane.
		Anticonvulsants that may be susceptible to interactions with phenytoin include carbamazepine, clonazepam, phenobarbital, and primidone.
	www.parkinsons-information-exchange-network-online.com /drugdb/103.html (3586 words)

	Convulsant and Anticonvulsant Effects on Spontaneous CA3 Population Bursts -- Yee et al. 89 (1): 427 -- Journal of ...
		interburst interval and burst duration, and convulsant or anticonvulsant
		An anticonvulsant results in burst termination before synapses are fully depressed by raising the burst end threshold.
		Anticonvulsant and proconvulsant actions of alpha- and beta-noradrenergic agonists on epileptiform activity in rat hippocampus in-vitro.
	jn.physiology.org /cgi/content/full/89/1/427 (5801 words)

	Valproic Acid, Depakene Syrup, Depakene, Depakote, Divalproex Sodium, Sodium Valproate
		Two infants born to women taking high doses of phenytoin and phenobarbital while pregnant developed jitteriness and tetany (a syndrome characterized by muscle twitches), cramps, and spasms that can be caused by calcium deficiency during the first two weeks of life.
		People taking anticonvulsant drugs should discuss with their doctor whether supplementing with vitamin B6 is advisable.
		One study revealed that individuals on long-term anticonvulsant therapy had dramatically lower levels of vitamin B12 in their cerebrospinal fluid (the fluid that bathes the brain) when compared with people who were not taking seizure medications.
	www.truestarhealth.com /Notes/1535009.html (2737 words)

	Practice parameter: Anticonvulsant prophylaxis in patients with newly diagnosed brain tumors: Report of the Quality ...
		anticonvulsant use in patients with brain tumors (table 4).
		Anticonvulsant usage is associated with an increased risk of procarbazine hypersensitivity reactions in patients with brain tumors.
		The impact of anticonvulsants on CPT-11 dose in patients with recurrent malignant glioma.
	www.neurology.org /cgi/content/full/54/10/1886 (3721 words)

	Anticonvulsant Screening Program: National Institute of Neurological Disorders and Stroke (NINDS)
		The Anticonvulsant Screening Program (ASP) is a government sponsored effort to encourage and to facilitate the discovery of new therapeutic agents for the treatment of seizure disorders.
		The ASP has as its major goal the establishment of worldwide collaborative relationships among the government, academia, and industry to search for a cure of the epilepsies and to provide the necessary incentives for discovery, characterization, and development of novel antiseizure/anticonvulsant agents.
		These efforts are directed toward anticonvulsant drug development and discovery of new mechanisms of drug action.
	www.ninds.nih.gov /funding/research/asp (1406 words)

	Management of Seizures - Current Concepts (Site not responding. Last check: 2007-10-06)
		Anticonvulsant blood levels are a general guideline for the therapeutic dose.
		There are general anticonvulsant side effects that occur with many different anticonvulsants; there are also specific anticonvulsant side effects that occur with one or a few anticonvulsants.
		Use of an anticonvulsants increases the risk for a foot fracture in elderly women and this risk is independent of the effects on bone mineral density (Seeley et al., 1996).
	www.neuro.mcg.edu /amurro/epilepsy/szsyl.htm (6839 words)

	Psychiatric Uses of Lamotrigine
		Lamotrigine is an anticonvulsant that is chemically unrelated to any other anticonvulsant or mood regulating medication.
		Anticonvulsants and antipsychotics in the treatment of bipolar disorder.
		A history of the use of anticonvulsants as mood stabilizers in the last two decades of the 20th century.
	www.psycom.net /depression.central.lamotrigine.html (3526 words)

	Anticonvulsant drug poses greater birth-defect risk than suspected, study
		Use of the anticonvulsant drug valproate during pregnancy may pose a significantly great risk of birth defects than does use of other antiseizure medications.
		While the risk level among women taking valproate was 10.7 percent, the risk for women in the registry who took other anticonvulsants as single-drug therapy was only 2.9 percent.
		In a comparison group of infants whose mothers had not taken an anticonvulsant drug, the frequency of major malformations in infants born to women at Brigham and Women's Hospital was 1.6 percent.
	www.medicalnewstoday.com /medicalnews.php?newsid=21627 (717 words)

	Klonopin. Information. Prices. (Site not responding. Last check: 2007-10-06)
		Clonazepam (marketed by Roche under the trade-name Klonopin� in the United States and Rivotril� in Canada and Europe) is an anticonvulsant sedative-hypnotic anxiolytic (anti-anxiety drug), and a member of the benzodiazepine class of drugs.
		Because of strong anxiolytic properties and euphoriant side-effects it is said to be among the class of 'highly potent' benzodiazepines with a higher risk of abuse, misuse and dependence than other benzodiazepines.
		Clonazepam (marketed by Roche under the trade-name Klonopin� in the United States and Rivotril� in Canada and Europe) is an anticonvulsant sedative-hypnotic anxiolytic (anti-anxiety drug), and a member of the benzodiazepine class of drugs klonopin cause Like other benzodiazepines, Clonazepam is believed to act by simulating the action of GABA on the central nervous system.
	klonopin.sphosting.com (1572 words)

	Anticonvulsant Hypersensitivity Syndrome
		Anticonvulsant Hypersensitivity Syndrome (AHS) is a drug-induced, multiorgan syndrome which is potentially fatal.
		Anticonvulsant Hypersensitivity Syndrome should be considered in any patient treated with phenytoin, carbamazepine or phenobarbitone who presents with fever, rash or lymphadenopathy.
		Anticonvulsant toxicity in vitro: possible role of arene oxides.
	www.medsafe.govt.nz /Profs/PUarticles/6.htm (908 words)

	NGC - NGC Summary
		In contrast, deleterious interactions with cytotoxic drugs and corticosteroids are a major concern, and the incidence and severity of anticonvulsant side effects appear to be appreciably higher (20 to 40%) in brain tumor patients than in the general population of patients receiving anticonvulsants.
		The available evidence suggests, however, that prophylactic administration of anticonvulsant medications does not provide substantial benefit (i.e., a risk reduction of 26% or more for seizure-free survival), whereas anticonvulsant-associated side effects are especially common and occasionally life-threatening.
		Although this may provide one explanation for the ineffectiveness of anticonvulsant prophylaxis in some patients, it did not change the conclusions of the one randomized controlled trial that addressed that issue specifically.
	www.guideline.gov /summary/summary.aspx?doc_id=2823&nbr=2049 (1301 words)

	aftershingles.com: Glossary
		The brand name of phenytoin, an anticonvulsant that is sometimes given to relieve the pain of post-herpetic neuralgia.
		An anticonvulsant that is sometimes given to patients with post-herpetic neuralgia.
		The brand name of carbamazepine, an anticonvulsant that is sometimes given to relieve the pain of post-herpetic neuralgia.
	www.aftershingles.com /glossary.html (952 words)

	ANTICONVULSANT EFFECTS OF CROCUS SATIVUS L (Site not responding. Last check: 2007-10-06)
		We studied the anticonvulsant activity of the aqueous and ethanolic extracts of CSS in mice in order to evaluate the traditional use of this plant.
		The mechanism (s) of anticonvulsant activity of the extracts is not clear.
		This study suggests that the ethanolic extract possesses a sedative effect, which is probably responsible for the anticonvulsant effect of the extracts.
	www.ams.ac.ir /AIM/0251/aim025144.htm (1407 words)

	Anticonvulsant drug use and low bone mass in adults with neurodevelopmental disorders -- Ray et al. 95 (4): 219 -- QJM
		Anticonvulsant drug use and low bone mass in adults with neurodevelopmental disorders -- Ray et al.
		Anticonvulsant drug use and low bone mass in adults with neurodevelopmental disorders
		Anticonvulsants and bone disease: a systematic overview of their association, and possible preventative strategies.
	qjmed.oxfordjournals.org /cgi/content/full/95/4/219 (2153 words)

	Pharmacokinetics and pharmacodynamics of vecuronium in children receiving phenytoin or carbamazepine for chronic ...
		or rocuronium was observed in patients on anticonvulsants.
		Differential effects of the anticonvulsants phenobarbital, ethosuximide, and carbamazepine on neuromuscular transmission.
		Atracurium-induced neuromuscular block is not affected by chronic anticonvulsant therapy with carbamazepine.
	bja.oxfordjournals.org /cgi/content/full/86/2/223 (2413 words)

Try your search on: Qwika (all wikis)