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Topic: Antihistaminergic

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Antihistamine

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Ethanolamine

	BioMed Central \| Full text \| In vivoantimuscarinic actions of the third generation antihistaminergic agent, ...
		Antihistaminergic drugs are commonly classified into three generations.
		In addition, while penetration of the blood-brain barrier by desloratadine is unlikely to occur at therapeutic doses [14], evidence has been obtained suggesting penetration can be achieved and result in significant central antimuscarinic effects if the blood-brain barrier is compromised by administration of a vasopressor agent.
		This was demonstrated by significant inhibition of oxotremorine-mediated positive and negative inotropic events and bradycardia by desloratadine in the pithed rat.
	www.biomedcentral.com /1471-2210/5/13 (5151 words)

	antihistaminergic (Site not responding. Last check: 2007-11-06)
		antihistaminergic is one of the topics in focus at Global Oneness.
		Brompheniramine Brompheniramine is an antihistaminergic medication of the propylamine class.
		It is commonly available over the counter and is indicated for the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing.
	www.experiencefestival.com /antihistaminergic (441 words)

	Evidence for feeding elicited through antihistaminergic effects of tricyclic antidepressants in the rat hypothalamus. (Site not responding. Last check: 2007-11-06)
		Evidence for feeding elicited through antihistaminergic effects of tricyclic antidepressants in the rat hypothalamus.
		Evidence for feeding elicited through antihistaminergic effects of tricyclic antidepressants in the rat hypothalamus.The tricyclic compounds amitriptyline, doxepin and imipramine significantly induced feeding after their infusion into the third cerebral ventricle in the light phase, but the tricyclic, desipramine, and the dicyclic zimelidine, did not.
		To clarify the involvement of neuronal histamine in antidepressant-induced feeding, alpha-fluoromethylhistidine (FMH), a "suicide" inhibitor of histidine decarboxylase, was intraperitoneally administered before infusion of amitriptyline.
	www.pdg.cnb.uam.es /UniPub/iHOP/gp/6506353.html (177 words)

	Treatment Strategies for Thyroid Dysfunction (Site not responding. Last check: 2007-11-06)
		As discussed these measures may have little or no role in controlling the drug-induced weight gain, but can help reduce risk factors associated with being overweight.
		Drugs with antihistaminergic properties may cause sedation, resulting in reduced mobility.
		Patients should be encouraged to maximize their daily physical activity to increase their total energy expenditure.
	www.continuingeducation.com /pharmtech/weightgain/8_Weight_Gain.html (230 words)

	antihistamine Resource Center - antihistamines
		An allergy testing antihistamines antihistamine is a drug which serves to reduce or eliminate effects mediated by histamine, an endogenous chemical mediator released during allergic reactions, through action at the histamine receptor.
		These are the oldest antihistaminergic drugs and are relatively inexpensive antihistamine medicine and widely available.
		baby antihistamine (Nelson, 2002) They are also structurally-related to the tricyclic antidepressants, explaining antihistamine eyedrops the antihistaminergic adverse effects of those two drug classes and also the poor tolerability profile of tricyclic H
	www.taxgloss.com /Tax-Genericized_Trademark_A_-_C-/antihistamine.html (1176 words)

	Antihistamine Encyclopedia Article @ Gasped.org (Site not responding. Last check: 2007-11-06)
		Only agents where the main therapeutic effect is mediated by negative modulation of histamine receptors are termed antihistamines - other agents may have antihistaminergic action but are not true antihistamines.
		Polar moiety on the side chain - thiourea, isothiourea and guanidine
		Recherches sur l'action sympathicolytique d'un nouveau derive du dioxane.
	www.gasped.org /encyclopedia/Antihistamine (1199 words)

	NSDL Metadata Record -- <it>In vivo </it>antimuscarinic actions of the third generation antihistaminergic ...
		NSDL Metadata Record -- In vivo antimuscarinic actions of the third generation antihistaminergic agent, desloratadine
		antimuscarinic actions of the third generation antihistaminergic agent, desloratadine
		Muscarinic receptor mediated adverse effects, such as sedation and xerostomia, significantly hinder the therapeutic usefulness of first generation antihistamines.
	nsdl.org /mr/1437717 (245 words)

	Nefazodone ( Serzone, Dutonin ) (Site not responding. Last check: 2007-11-06)
		Analyses of pooled clinical trial results indicate that nefazodone and imipramine produces similar and significant improvements on anxiety- and agitation-related rating scales compared with placebo in patients with major depression.
		Short term tolerability data indicate that nefazodone has a lower incidence of adverse anticholinergic, antihistaminergic and adrenergic effects than imipramine.
		Compared with SSRIs, nefazodone causes fewer activating symptoms, adverse gastrointestinal effects (nausea, diarrhoea, anorexia) and adverse effects on sexual function, but is associated with more dizziness, dry mouth, constipation, visual disturbances and confusion.
	www.biopsychiatry.com /nefazodone.htm (330 words)

	eMedicine - Toxicity, Cyclic Antidepressants : Article Excerpt by: Vivian Tsai, MD (Site not responding. Last check: 2007-11-06)
		The same mechanism is thought to be responsible for seizure occurrence in CA overdose.
		Altered mental status is also frequently seen in CA overdose and is mainly attributed to anticholinergic and antihistaminergic properties of CAs.
		The effects of CA overdose on the cardiovascular system result mainly from CAs' impediment of the cardiac conduction system.
	www.emedicine.com /emerg/byname/toxicity-cyclic-antidepressants.htm (618 words)

	Antidepressants : mechanisms of action (Site not responding. Last check: 2007-11-06)
		The next step was the development of mixed serotonin-norepinephrine reuptake inhibitors (SNRIs), exemplified by venlafaxine and milnacipran.
		As with the TCAs, the antidepressant activity of SNRIs is based on inhibition of norepinephrine and serotonin reuptake, but unlike TCAs they do not have anticholinergic, antihistaminergic, and cardiotoxic effects.
		Although norepinephrine is known to stimulate serotonin cell firing rate via the alpha1-adrenoceptors, norepinephrine and serotonin have independent antidepressant actions.
	www.biopsychiatry.com /tricevo.htm (249 words)

	14rc4
		In addition TCAs have a number of other actions with specific side effects: antihistaminergic, causing drowsiness and weight gain, anticholinergic/antimuscarinic causing constipation, blurred vision, dry mouth and drowsiness, alpha
		In addition, they do not have antihistaminergic, anticholinergic, or alpha 1 adrenergic actions and side effects.
		The inhibition of the reuptake of 5HT is believed to lead to an antidepressant effect by stimulation of the 5HT
	www.euroanesthesia.org /education/rc_amsterdam/14rc4.HTM (2565 words)

	Brain Explorer - Focus on Brain Disorders - Depression - Treatment (Site not responding. Last check: 2007-11-06)
		TCAs act by inhibiting the uptake of both noradrenaline and serotonin in the synaptic cleft
		TCAs with strong antihistaminergic properties, such as doxepin and amitriptyline, have sedative properties that are useful when treating patients with insomnia.
		Disadvantages of the TCAs may include daytime sedation, anticholinergic side effects, orthostatic hypotension, cardiotoxicity, toxic psychosis and initial worsening of the condition.
	www.brainexplorer.org /depression/Depression_Treatment.shtml (2141 words)

	Atomoxetine: New Treatment For AD/HD
		Their anticholinergic effects can cause constipation, dry mouth and dry eyes.
		Their antihistaminergic effects can cause weight gain and tiredness.
		Their alpha adrenergic effects can cause tremor and changes in blood pressure.
	www.baltimorepsych.com /Strattera.htm (1611 words)

	[No title]
		Patients with Parkinsons Disease also utilize the drug to prevent dyskinesia.
		It is a member of ethanolamine class of antihistaminergic agents and is a H1 receptor antagonist.
		Antagonism is achieved through blocking the effect of histamine more than blocking its production or release.
	www.humboldt.edu /~morgan/ben3_s05.htm (2763 words)

	IngentaConnect Psychiatric Disorders Associated with Traumatic Brain Injury: Opt... (Site not responding. Last check: 2007-11-06)
		However, adjustments in these approaches must be made to account for the adverse effect profiles of the drugs used that may worsen cognitive function.
		Medications with prominent anticholinergic, antihistaminergic or antidopaminergic effects should therefore not be used as first-line interventions.
		In addition, traditional antipsychotics may block synaptic plasticity and so should be used with caution in patients with TBI.
	www.ingentaconnect.com /content/adis/cns/1998/00000009/00000006/art00003 (318 words)

	CIPRAMIL 20 mg Tablets
		Citalopram has no effect on the uptake of noradrenaline, dopamine or GABA.
		Moreover neither citalopram nor its metabolites have antidopaminergic, antiadrenergic, antiserotoninergic, antihistaminergic or anticholinergic (antimuscarinic) properties.
		After prolonged treatment, the 5-HT- uptake inhibitory efficacy is unchanged and citalopram does not induce changes in the density of neurotransmitter receptors at the recommended dosages.
	home.intekom.com /pharm/lundbeck/cipramil.html (960 words)

	Meridia Capsules Drug Information Meridia Capsules
		Following chronic administration of sibutramine to rats, no depletion of brain monoamines has been observed.
		exhibit no evidence of anticholinergic or antihistaminergic actions.
		In addition, receptor binding profiles show that sibutramine, M
	www.drugs.com /PDR/Meridia_Capsules.html (6967 words)

	Parkinson's disease news and information
		The fewer pills I have to take, the better."
		According to the Parkinson’s Disease Foundation, many common allergy mediations, which are used medically for antihistaminergic and antiemetic purposes, contain anticholinergic agents that have the same effect as those for the treatment of Parkinson’s Disease.
		Stopping the use of these allergy medications could eliminate an increased chance of confusion, sleepiness and memory problems in Parkinson’s patients.
	www.nwpf.org /articles.asp?id=1808 (710 words)

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