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	Definition of antitussive - Merriam-Webster Online Dictionary
		Learn more about "antitussive" and related topics at Britannica.com
		Find more about "antitussive" instantly with Live Search
		See a map of "antitussive" in the Visual Thesaurus
	www.m-w.com /cgi-bin/dictionary?book=Dictionary&va=antitussive (26 words)

	TORAY \| Press Releases \| Co-development in Japan of a non-narcotic antitussive which has a new action mechanism
		Antitussive (so-called "cough remedy") is widely used in the treatment of coughs caused by "colds" to acute and chronic respiratory diseases including bronchitis, pneumonia, etc. Antitussives are roughly classified into "narcotic antitussives" (codeine phosphate, etc.) and "non-narcotic antitussives".
		Though the "narcotic antitussives" demonstrate excellent effect, they cause adverse reactions such as drug dependency, constipation, sleepiness, respiratory restraint, etc. The adverse reactions caused by the "non-narcotic antitussives" are milder and therefore this type of antitussive is frequently used in the initial stage of treatment.
		As a drug with potent antitussive action but with less adverse reactions, this new compound is expected to improve the quality of life (QOL) in the patients through suppressing the cough caused by various acute and chronic respiratory diseases.
	www.toray.com /news/medical/nr000515.html (611 words)

	Antitussive effect of Rosa damascena in (Site not responding. Last check: )
		Therefore, in the present study the antitussive effect of this plant in guinea pigs was evaluated.
		The antitussive effect of aerosols of two different concentrations of ethanolic extract (5 and10% w/v), aqueous extract (10 and 20% w/v), codeine, and saline were tested counting the number of cough produced due to aerosol of citric acid 10 min after exposing animal to aerosols of different solutions (n=6 for each solution).
		In addition the numbers of coughs obtained in the presence of both concentrations of ethanolic extract and higher concentrations of aqueous extract were not significantly different from that of codeine.
	www.ijpr-online.com /Docs/20034/IJPR169a.htm (282 words)

	Cough \| Full text \| Effect of N-arachidonoyl-(2-methyl-4-hydroxyphenyl) amine (VDM11), an anandamide transporter ...
		This antitussive effect was antagonized by pretreatment with either intraperitoneal administration (3 mg/kg) or inhalation (1 mg/ml) of SR141716A, a cannabinoid receptor (CB1) antagonist.
		Antitussive effects of VDM11 (10 mg/kg subcutaneously) on capsaicin-induced cough reached a peak 60 min after injection, gradually declined and then returned to the pre-injection level 180 min after the administration of VDM11 (Fig.
		This antitussive effect of VDM11 was significantly antagonized by pretreatment with SR141716A, a cannabinoid CB1 receptor antagonist.
	www.coughjournal.com /content/2/1/2 (3136 words)

	Efficacy of Herbal Substances According to Cough Reflex - Health - RedOrbit
		Antitussive activity of the selected plant carbohydrate substances was tested on conscious cats by mechanical stimulation of the laryngopharyngeal and tracheobronchial mucous areas of the airways through a surgically implanted endotracheal cannula.
		Antitussive activity of the plant constituents was compared with the same ability of opiate agonist codeine in the dose 10 mg.kg^sup -1^ body wt and with a cough suppressive effect of peripherally acting dropropizine (100 mg.kg^sup-1^ body wt).
		The high antitussive effect and rare adverse reactions are the reason why the herbal compounds are to be considered as prospective drugs able to influence the cough reflex.
	www.redorbit.com /news/health/309231/efficacy_of_herbal_substances_according_to_cough_reflex/index.html?source=r_health' (4703 words)

	Antitussive
		Another serious side effect is neuroleptic malignant antitussive syndrome, in which the drugs appear antitussive to cause the temperature antitussivr regulation centers antuitussive to fail, anttiussive resulting in a medical emergency as the patient's temperature suddenly increases to dangerous levels.
		antitussiive the influenza virus are the columnar epithelial antitussive cells of antitussuve the respiratory antityssive tract.
		A textbook editor antitussive who has skilled authors who present their material in antitussive an inadequate order and in a form that is barely comprehensible, antitussive has to antitussive take the revision antitussiv of the chapters into his own hands.
	fvoe.biz /antitussive (2406 words)

	EPA: Federal Register: Cold, Cough, Allergy, Bronchodilator, and Antiasthmatic Drug Products for Over-The-Counter Human ...
		If menthol were used only as a flavor in any of these antitussive or anesthetic/analgesic products, then it must be used at an amount less than the minimum dosage for the product's indication(s); otherwise it would be deemed to be present in the product at a therapeutic level and would be considered active.
		The Panel determined that products containing an antitussive or a nasal decongestant combined with a topical oral anesthetic/analgesic in a lozenge dosage form are rational, identified a target population that would benefit from such products, and recommended classifying such products in category I (41 FR 38312 at 38325).
		Noting the proposed category I status of the combination of camphor, eucalyptus oil, and menthol in an ointment dosage form for antitussive use (53 FR 30522 at 30547), the comment argued that inhalation of vapors by evaporation from a liquid at ambient temperature or from a topically applied ointment are comparable.
	www.epa.gov /fedrgstr/EPA-IMPACT/2002/December/Day-23/i32158.htm (12695 words)

	FR Doc 02-32158
		If menthol were used only as a flavor in any of these antitussive or anesthetic/analgesic products, then it must be used at an amount less than the minimum dosage for the product's indication(s); otherwise it would be deemed to be present in the product at a therapeutic level and would be considered active.
		The Panel determined that products containing an antitussive or a nasal decongestant combined with a topical oral anesthetic/analgesic in a lozenge dosage form are rational, identified a target population that would benefit from such products, and recommended classifying such products in category I (41 FR 38312 at 38325).
		Noting the proposed category I status of the combination of camphor, eucalyptus oil, and menthol in an ointment dosage form for antitussive use (53 FR 30522 at 30547), the comment argued that inhalation of vapors by evaporation from a liquid at ambient temperature or from a topically applied ointment are comparable.
	a257.g.akamaitech.net /7/257/2422/14mar20010800/edocket.access.gpo.gov/2002/02-32158.htm (12625 words)

	hydrocodone cough syrup
		hydrocodone cough syrup is a narcotic analgesic used in combination products to relieve mild to moderate pain and an antitussive agent to relieve cough and upper respiratory symptoms associated with allergy or cold.
		description hydrocodone cough syrup is an antitussive (cough suppressant) and analgesic agent for the treatment of moderate to moderately severe pain.
		hydrocodone best price on the web is an effective antitussive hydrocodone best price on the web (anti-cough) agent, and as an opiate it is also an effective analgesic for mild to hydrocodone best price on the web moderate pain control.
	www.cheap-hydrocodone.com /hydrocodone/hydrocodone-cough-syrup.html (1104 words)

	Antitussive
		Amphetamine, cocaine, phencyclidine and nomifensine antitussive increase extracellular dopamine concentrations preferentially in the nucleus accumbens of freely- moving rats.
		The pons is a relay station for signals being carried from the antitussive cortex to the cerebellum, which is involved in body movements and coordination.
		It is antitussive involved in antitussive regulation of mood, arousal, impulsivity, aggression, appetite and anxiety.
	wpof.biz /antitussive/index.html (2696 words)

	Antitussive - Search Results - MSN Encarta
		Antitussive, any substance administered to suppress a cough.
		antitussive - definition of antitussive in the Medical dictionary - by...
		If an overactive gag reflex is a problem, some patients respond to the addition of 1 or 2 100-mg...
	encarta.msn.com /Antitussive.html (142 words)

	Antitussive
		The mutants are as virulent and transmissible antitussive as the wild-type virus.
		The effects of hallucinogens are quite antitussive similar between classes of drugs within antitussiev this category, and range from excitation or depressant effects, analgesic and anaesthetic effects, depending on the dose taken and the situation.
		Psychoactive substance use may antitussive reflect self-medication intended to anritussive reverse some of the abnormalities associated with mental illness; these abnormalities may have existed prior to substance use or may have been caused by the substance use.
	fgrfg.info /antitussive (2067 words)

	Antitussive effect of the GABA-agonist baclofen - gamma-aminobutyric acid CHEST - Find Articles (Site not responding. Last check: )
		The impact of cough on the general population is highlighted by the fact that antitussive agents are the leading category of "over-the-counter" medications sold, accounting for over a half billion dollars in annual sales in the United states.[1]
		An increase in the sensitivity of the cough reflex has been proposed as a potential etiology of chronic, nonproductive cough.[1] Often, this symptom is not responsive to standard antitussive therapy.
		Although codeine may be an effective cough suppressant, its sedating properties, inhibition of gastric motility, and potential for abuse render it an unsatisfactory option for chronic or even intermittent control of bothersome cough.
	www.findarticles.com /p/articles/mi_m0984/is_n4_v111/ai_19365620 (690 words)

	Influence of central antitussive drugs on the cough motor pattern -- Bolser et al. 86 (3): 1017 -- Journal of Applied ...
		This is the first report to investigate the central actions of antitussive drugs on the cough motor pattern.
		Antitussive effects of GABA-B agonists in the cat and guinea pig.
		Central antitussive activity of the tachykinin receptor antagonists CP-99994 and SR-48968 in the guinea pig and cat.
	jap.physiology.org /cgi/content/full/86/3/1017 (4375 words)

	Antitussive Drugs - The Merck Veterinary Manual
		Most of the antitussive drugs are opiates or opioids that directly suppress the cough center in the medulla oblongata (Table: Antitussive Drugs).
		The antitussive effect does not appear to be related to the binding of traditional opiate receptors.
		It is not commonly used for antitussive activity due to side effects and the potential for abuse and addiction.
	www.merckvetmanual.com /mvm/htm/bc/190901.htm (408 words)

	Accentia BioPharmaceuticals \| Respi-TANN® (Site not responding. Last check: )
		Respi-TANN® Pd is indicated for temporary relief of cough accompanying respiratory tract conditions associated with the common cold, influenza, sinusitis, and bronchitis and for the relief of nasal congestion associated with the common cold, sinusitis and acute upper respiratory infections.
		Non-Drowsy Respi-TANN® Pd is the only antitussive available that conforms to revised US Food and Drug Administration guidance for the dosing of Carbetapentane Citrate for children under 12 years of age.
		NewNon-Drowsy Respi-TANN® G is the only antitussive available that conforms to revised US Food and Drug Administration guidance for the dosing of Carbetapentane Citrate for children under 12 years of age.
	www.accentia.net /science/respi_tann.php (312 words)

	Dextromethorphan antitussive compositions - Patent 5196436
		The subject invention involves antitussive pharmaceutical compositions for the peroral administration of dextromethorphan, the composition being at a pH of from about 8 to about 11.
		A safe and effective amount of drug active will vary with the particular condition being treated, the age and physical condition of the patient being treated, the severity of the condition, the duration of the treatment, the nature of concurrent therapy and like factors.
		Dextromethorphan is known to have pharmacological activity as an antitussive agent.
	www.freepatentsonline.com /5196436.html (2722 words)

	FDA > CDRH > CFR Title 21 Database Search
		Diphenhydramine citrate in 341.12(f) and 341.14(a)(5) or diphenhydramine hydrochloride in 341.12(g) and 341.14(a)(6) may be both the antihistamine and the antitussive active ingredient provided that the product is labeled according to 341.70(a).
		Menthol in 341.14(b)(2) and part 356 of this chapter may be both the antitussive and the anesthetic/analgesic active ingredient provided that the product is labeled according to 341.70(b).
		(l) Any single oral antitussive active ingredient identified in 341.14(a) may be combined with any generally recognized as safe and effective single analgesic-antipyretic active ingredient, or any combination of acetaminophen with other analgesic-antipyretic active ingredients, or any aspirin and antacid combination provided that the product is labeled according to 341.85.
	www.accessdata.fda.gov /scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=341.40 (913 words)

	UNODC - Bulletin on Narcotics - 1977 Issue 1 - 004
		Its potency is reported to be 14 to 25 times that of codeine phosphate in mechanical stimulation in guinea-pigs, 5 to 10 times in the ammonia gas method in guinea-pigs and 50 times in mechanical stimulation in dogs.
		It has also been reported that the respiratory depressant effect of the drug was not observable at the antitussive doses in unanesthetized dogs and was weaker than that of codeine phosphate in anesthetized cats and dogs (Kobayashi, Hasegawa, Mori and Takagi, 1970).
		Clinically, a potent antitussive effect of drotebanol was observed by many investigators and it has been reported that the potency of the drug effect at oral doses of 4 mg/person was equal to or even stronger than that of codeine at 20 mg/person (Takijima et al., 1970).
	www.unodc.org /unodc/bulletin/bulletin_1977-01-01_1_page005.html (3478 words)

	Patent 6,001,392
		The amount of resinate in the formulation is sufficient to deliver, when administered at one dose every 12 hours, an antitussive effective amount of a drug like dextromethorphan over a period of approximately 12 hours to a patient in need of such administration.
		The antitussive drugs that are suitable for use in these preparations are acidic, amphoteric or most often basic antitussives.
		The bioavailability of dextromethorphan from the compositions of the present invention is high despite the strong bond between residual amounts of dextromethorphan and the ion exchange resin.
	www.pharmcast.com /Patents/121499OG/6001392_antitussive121499.htm (3981 words)

	Antitussive offers convenient twice-daily dosing - Drug Topics
		Reduced dosage of codeine/chlorpheniramine is recommended when the combo drug is used with MAOIs, tricyclic antidepressants, or central nervous system depressants such as antipsychotics or antianxiety agents.
		Antitussive activity should be monitored in those taking cytochrome P450 enzyme inducers or inhibitors, the manufacturer said.
		Celltech reported that the most common side effects associated with the use of codeine/chlorpheniramine in clinical trials include drowsiness, confusion, dizziness, nausea, constipation, dry mouth, headache, and allergic reactions.
	www.drugtopics.com /drugtopics/article/articleDetail.jsp?id=109909 (650 words)

	Temaril P Rx -1000ct
		Antitussive: Temaril-P has been found to be effective therapy and adjunctive therapy in various cough conditions of dogs.
		Therefore, in addition to its antipruritic action, Temaril-P is recommended for the treatment of “kennel cough” or tracheobronchitis, bronchitis including all allergic bronchitis and infections and coughs of nonspecific origin.
		The same dosage schedule may be followed for both antipruritic and antitussive therapy.
	www.agri-med.com /site/255063/product/TEMARILP-1000CT (719 words)

	Use of Codeine- and Dextromethorphan-Containing Cough Remedies in Children -- Committee on Drugs 99 (6): 918 -- ...
		Cough is a reflex response to mechanical, chemical, or inflammatory irritation of the tracheobronchial tree mediated by sensory
		Demonstration of the efficacy of antitussive preparations in children is lacking, and these medications may be potentially
		Other narcotic antitussives that are available in cough preparations, such as hydrocodone and hydromorphone, have no demonstrated
	pediatrics.aappublications.org /cgi/content/full/99/6/918 (1503 words)

	The Antitussive Effect of Placebo Treatment on Cough Associated With Acute Upper Respiratory Infection -- Lee et al. 67 ...
		The Antitussive Effect of Placebo Treatment on Cough Associated With Acute Upper Respiratory Infection -- Lee et al.
		Freestone C, Eccles R. Assessment of the antitussive efficacy of codeine in cough associated with common cold.
		Lee PCL, Jawad MSM, Eccles R. Antitussive efficacy of dextromethorphan in cough associated with acute upper respiratory tract infection.
	www.psychosomaticmedicine.org /cgi/content/full/67/2/314 (2904 words)

	Cough: Approach to the Patient With Pulmonary Symptoms: Merck Manual Professional
		Nonspecific treatments for cough should be reserved as much as possible for patients with a URI and for those receiving therapy for the underlying cause but for whom cough is still troubling.
		Codeine has antitussive, analgesic, and sedative effects, but dependence is a potential problem, and nausea, vomiting, constipation, and tolerance are common adverse effects.
		is not generally considered an antitussive but may be of use in some patients with acute cough due to URI.
	www.merck.com /mmpe/sec05/ch045/ch045c.html (1048 words)

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