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| | Medmicro Chapter 52 (Site not responding. Last check: 2007-10-09) |
 | | Antiviral compounds that have been formally licensed for clinical use are amantadine, rimantadine, ribavirin, idoxuridine, trifluridine, vidarabine, acyclovir, ganciclovir, foscarnet, zidovudine, didanosine, zalcitabine, stavudine, famciclovir and valaciclovir (Fig. |
 | | Antiviral compounds can be divided into two categories (Table 52-3): (1) those that can interact directly with their target and (2) those that must first be activated intracellularly by phosphorylation to the active (generally triphosphate) forms. |
 | | Antiviral selectivity may stem from the specific affinity of the antiviral compounds (or their activated forms) for their target protein (or enzyme). |
| gsbs.utmb.edu /microbook/ch052.htm (0 words) |
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