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Topic: Arava

	Answers about Arava and why it was prescribed to help relieve rhemuatoid arthritis (RA) pain
		Arava was studied in males and females, younger and older adults, those just diagnosed with RA, and those who have had it for several years.
		Arava can cause an increase in liver enzymes or, in rare cases, liver injury, with the potential to be life threatening.
		Arava is not recommended for patients with significant liver disease or hepatitis B or C. In clinical studies with Arava, liver enzymes were elevated in a significant number of Arava patients
	www.arava.com /patient/about_arava/arava_medication_faqs.do (1620 words)

	Leflunomide (marketed as Arava): Consumer Informatin Sheet
		Arava is used to treat active rheumatoid arthritis in adults to reduce signs and symptoms, slow down damage to joints, and improve physical function.
		Arava is not indicated in children or adolescents with juvenile rheumatoid arthritis.
		You must not take Arava if you are pregnant or a woman of childbearing age not using reliable contraception because in animal studies Arava has been shown to cause birth defects to the fetus.
	www.fda.gov /cder/consumerinfo/druginfo/Arava.HTM (393 words)

	Official Arava FDA information, side effects and uses.
		ARAVA was statistically significantly superior to placebo in reducing the signs and symptoms of RA by the primary efficacy analysis, ACR20 Responder at Endpoint, in study US301 (at the primary 12 months endpoint) and MN301 (at 6 month endpoint).
		ARAVA was statistically significantly superior to placebo in inhibiting the progression of disease by the Sharp Score.
		ARAVA was studied in a single multicenter, double-blind, active-controlled trial in 94 patients (1:1 randomization) with polyarticular course juvenile rheumatoid arthritis (JRA) as defined by the American College of Rheumatology (ACR).
	www.drugs.com /pro/arava.html (6868 words)

	Arava Prescribing Information - Aventis Pharmaceuticals
		ARAVA was statistically significantly superior to placebo in reducing the signs and symptoms of RA by the primary efficacy analysis, ACR20 Responder at Endpoint, in study US301 (at the primary 12 months endpoint) and MN301 (at 6 month endpoint).
		ARAVA was statistically significantly superior to placebo in inhibiting the progression of disease by the Sharp Score.
		ARAVA was studied in a single multicenter, double-blind, active-controlled trial in 94 patients (1:1 randomization) with polyarticular course juvenile rheumatoid arthritis (JRA) as defined by the American College of Rheumatology (ACR).
	products.sanofi-aventis.us /arava/arava.html (6118 words)

	Arava (Leflunomide) drug warnings and precautions - prescription drugs and medications at RxList
		ARAVA is not recommended for patients with severe immunodeficiency, bone marrow dysplasia, or severe, uncontrolled infections.
		In clinical trials, ARAVA treatment as monotherapy or in combination with methotrexate was associated with elevations of liver enzymes, primarily ALT and AST, in a significant number of patients; these effects were generally reversible.
		Given the possible risk of increased hepatotoxicity, and the role of the liver in drug activation, elimination and recycling, the use of ARAVA is not recommended in patients with significant hepatic impairment or evidence of infection with hepatitis B or C viruses.
	www.rxlist.com /cgi/generic/leflunomide_wcp.htm (2249 words)

	ARAVA LAWYER
		Two Arava deaths have been people in their 20s.
		This petition was not the first indicator that serious and deadly Arava side effects can occur.
		Arava is also dangerous because it remains in the body tissues for an extended amount of time.
	www.arava-lawyer.com (958 words)

	ACR: Arava Safety And Efficacy Confirmed For RA (Site not responding. Last check: 2007-10-26)
		Arava is contraindicated in pregnant women or women of childbearing potential who are not using reliable contraception.
		Arava was associated with elevations in liver enzymes, primarily ALT and AST, in a significant number of patients in clinical trials.
		Arava is not recommended in patients with significant hepatic impairment or positive hepatitis B or C serologies given the risk of increased hepatotoxicity.
	www.pslgroup.com /dg/1469DE.htm (1189 words)

	ACR: Arava Safety And Efficacy Confirmed For RA (Site not responding. Last check: 2007-10-26)
		Arava is contraindicated in pregnant women or women of childbearing potential who are not using reliable contraception.
		Arava was associated with elevations in liver enzymes, primarily ALT and AST, in a significant number of patients in clinical trials.
		Arava is not recommended in patients with significant hepatic impairment or positive hepatitis B or C serologies given the risk of increased hepatotoxicity.
	www.docguide.com /dg.nsf/PrintPrint/018BCF5E1931F1668525682A00503267 (1208 words)

	Arava
		Arava is a prescription drug for rheumatoid arthritis that has recently been linked to severe liver problems (hepatoxicity) and several deaths since it has been on the market.
		For 12 cases that were fatal, liver damage from Arava "appears to be the most plausible explanation," the group said.
		Arava is a widely prescribed medication used for the treatment of Arthritis.
	www.texasinjurylaw.com /arava_lawsuit.htm (357 words)

	The Central Arava
		The Central Arava region borders on the Tamar Regional Council to the north, the Hevel Eilot Council to the South, the Ramat Negev Council to the west, and the Kingdom of Jordan to the east.
		The Arava is not connected to the national water system, but is supplied by local wells.
		Some of the Arava wells are now in Jordanian territory, following the determination of the international border made as part of the peace accords between the two countries.
	www.arava.co.il /english/about/aboutus.htm (1295 words)

	Arava / Leflunomide Lawsuit Information - Find Trial Lawyers and Attorneys with Experience in Arava / Leflunomide ...
		Arava, also known as leflunomide, is a drug used to treat arthritis.
		Arava is manufactured by Aventis Pharmaceuticals and was approved by the FDA in September 1998.
		Arava works by stopping the development of immune cells that cause inflammation, swelling, stiffness, and joint pain.
	www.injuryboard.com /view.cfm/Topic=726 (498 words)

	Arava - your on line General counsel since 1982
		Arava is a disease-modifying anti-rheumatic drug (DMARD) which reduces inflammation and slows disease progression of rheumatoid arthritis.
		Arava, classified as a DMARD (disease-modifying anti-rheumatic drug) is indicated for patients with active rheumatoid arthritis.
		When the FDA (U.S. Food and Drug Administration) approved Arava in September 1998, it was heralded as the first new treatment for rheumatoid arthritis in 10 years.
	www.leflaw.com /index.php?module=pagemaster&PAGE_user_op=view_page&PAGE_id=35 (310 words)

	Failure to Diagnose Heart Attack, Personal Injury Law Firm, St. Louis, Metro East, MO and Fairview, IL
		Arava was approved for treating rheumatoid arthritis by the Food and Drug Administration in September 1998.
		Arava side effects run from mild - such as diarrhea and hair loss - to serious, including the risk of liver damage (hepatotoxicity).
		Taking Arava can also affect the blood count (one of the effects is that fewer blood cells are made) and it can make you more likely to develop infections.
	www.brownandcrouppen.com /arava.html (764 words)

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		Arava® is a problem because it has been linked to serious health conditions and fatalities in several patients.
		Because of the potential for ARAVA levels to continue to increase with multiple dosing, caution should be used if patients are to be receiving both ARAVA and rifampin.
		Arava is not recommended in patients with significant liver disease or hepatitis B or C. Source:
	www.lycos.com /info/arava--patients.html (235 words)

	Arthritis Treatment - Arava - Arthritis and arthritic conditions, medications, and treatment on MedicineNet.com
		Arava compared favorably with medicines currently used, including sulfasalazine and methotrexate.
		According to the manufacturer, Hoechst Marion Roussel of Kansas City, MO, the effectiveness of Arava may be a result of its unique action to block a special enzyme (referred to as DHODH) that is involved in the autoimmune process that leads to rheumatoid arthritis.
		Arava is not recommended in patients with significant liver disease.
	www.medicinenet.com /script/main/art.asp?articlekey=6978 (460 words)

	Arava Lawyers - Arava Attorneys - Submit Case - Free Review
		Arava, also known as leflunomide, is a prescription drug used to treat rheumatoid arthritis, the most common form of arthritis.
		Arava was approved by the FDA in September, 1998.
		Arava (leflunomide) is a disease-modifying anti-rheumatic drug (DMARD), which not only relieves pain and inflammation but slows disease progression of joint destruction.
	www.gregjoneslaw.com /topic.asp?id=1034 (239 words)

	Arava
		Arava, also known as leflunomide and produced by Aventis, was first marketed in the United States in September 1998 to treat rheumatoid arthritis.
		Over the next three years, it was associated with at least 130 cases of severe liver toxicity, including 56 hospitalizations and 12 deaths, according to FDA data.
		Additionally, Arava has been associated with 12 cases of the life-threatening autoimmune disease Stevens-Johnson Syndrome, and methotrexate with none.
	www.bruha.com /pfpc/html/arava.html (934 words)

	FDA Panel Recommends Arava For Adult Rheumatoid Arthritis (Site not responding. Last check: 2007-10-26)
		If approved, Arava will be the first new disease modifying agent specifically developed for the treatment of rheumatoid arthritis -- a potentially crippling disease that affects more than two million Americans -- in more than a decade.
		The efficacy of Arava may be a result of its unique mechanism of action that works by reversibly inhibiting an enzyme (DHODH) involved in the autoimmune process that leads to rheumatoid arthritis.
		The committee further recommended that Arava not be used in pregnant women or in patients with significant liver disease.
	www.pslgroup.com /dg/9fa1a.htm (656 words)

	Arava \| Treatment \| International Still's Disease Foundation
		If you are currently taking Arava or have discontinued Arava and are going through the required drug elimination procedure, you and your partner should take every precaution to avoid becoming pregnant, such as both partners using reliable birth control as recommended by your doctor.
		After discontinuing Arava, your doctor will prescribe a drug elimination procedure consisting of a full 11-day course of drug elimination medication followed by 2 separate laboratory blood tests at least 14 days apart to assure a very low drug level in your body.
		Arava is not recommended for patients with serious immune deficiencies or severe uncontrolled infections.
	www.stillsdisease.org /treatment/arava (811 words)

	Arava, Leflunomide, side effects, drug interactions, overdose, dosage
		Arava is used in the treatment of rheumatoid arthritis.
		Arava does not appear to cause fetal harm when taken by the father prior to conception.
		Arava is not recommended for children less than 18 years old.
	www.pdrhealth.com /drug_info/rxdrugprofiles/drugs/ara1026.shtml (780 words)

	Medical Malpractice lawyers - hospital accidents - doctor injury attorneys, Pennsylvania
		Arava is a prescription drug for rheumatoid arthritis that has recently been linked to 130 cases of severe liver problems (hepatoxicity) and up to 22 deaths since it has been on the market.
		Arava is also dangerous because it remains in the body tissues for an extended amount of time.
		In addition, Arava is not viewed as having any superiority over other rheumatoid arthritis prescriptions it simply provided patients "more options." To learn more about your legal rights and any Arava side effects you have experienced, please contact us.
	www.munley.com /prescription_arava_faqs.html (788 words)

	Ohio Arava Attorney - Dangerous Drug Lawyers in Columbus (Site not responding. Last check: 2007-10-26)
		Arava® (leflunomide) is a prescription drug manufactured by Aventis Pharma for the treatment of rheumatoid arthritis.
		Arava® was linked to six times more reports of fatal liver toxicity and 13 times more reports of hypertension than Methotrexate.
		Additionally, with Arava® there were numerous cases of Stevens-Johnson syndrome, a life threatening auto-immune disease involving the skin and the mucous membranes, where with Methotrexate, there were none.
	www.rwklaw.com /arava.shtml (538 words)

	Drug Recalls - Arava Blamed For Liver Damage & Deaths
		Consumer groups warn that the public is largely unaware of the serious and life-threatening complications potentially associated with use of Arava, and are asking that the drug be removed from the market.
		According to one report, Arava was linked to six times more cases of fatal liver toxicity and 13 times more reports of hypertension than methotrexate, despite the fact that there were 6.8 million more prescriptions filled for methotrexate than Arava during that time.
		Arava side-effects include liver problems (elevated liver enzymes, yellowing of skin, blood in urine, etc.), hypertension (shortness of breath), blood disorders, high blood pressure, severe diarrhea and Stevens-Johnson syndrome.
	www.drugrecalls.com /arava.html (351 words)

	Arava (Leflunomide) drug description - prescription drugs and medications at RxList
		ARAVA IS CONTRAINDICATED IN ARAVA® (leflunomide) is a pyrimidine synthesis inhibitor.
		ARAVA is available for oral administration as tablets containing 10, 20, or 100 mg of active drug.
		Combined with leflunomide are the following inactive ingredients: colloidal silicon dioxide, crospovidone, hypromellose, lactose monohydrate, magnesium stearate, polyethylene glycol, povidone, starch, talc, titanium dioxide, and yellow ferric oxide (20 mg tablet only).
	www.rxlist.com /cgi/generic/leflunomide.htm (140 words)

	Arava Recall Lawyers - Arava Side Effects Attorneys - Arava Recall Information - 2002 Update
		ARAVA® is the brand name of lenflunomide, an anti-inflammatory prescription drug used to treat the symptoms of rheumatoid arthritis and is manufactured and marketed by Aventis Corporation.
		Based on reports made to the FDA, since ARAVA® was approved in 1998, it has been linked with at least 130 cases of severe liver damage and liver toxicity, including 56 hospitalizations and 12 deaths.
		According to Public Citizen Arava® remains in body tissues for an extremely long time, so that even if patients stopped the drug after an adverse reaction started, the damage could continue to affect them for months.
	www.lovt.com /AravaBanner.html (640 words)

	Arava: Arava And Birth Defects, Huntington Beach California Arava Lawyer
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	www.geocities.com /centralmgw/index-arava.html (531 words)

	[No title]
		Extensive coverage of the Arava Valley by birders over recent decades has led to the creation of a few well-known "hotspots", some of which are detailed below.
		In the lower parts of these cliffs and on the slopes in front of them, copper-rich nodules (up to 55% copper) mainly of malachite and chalcocite, were mined in ancient times.
		The spring (ein) – a source of fresh water in this desert region – and the strategic position of the hill at the intersection of the main Arava road and the Negev-Edom road were the reasons for the building of consecutive fortresses on this spot over the course of about 1000 years.
	www.lycos.com /info/arava--arava-valley.html (315 words)

	Sanofi-Aventis: Arava facing generic attack - Pharmaceutical Business Review
		Arava's patents have already expired in the EU but exclusivity may prevent generics in the EU up to 2009.
		Arava is an oral DMARD positioned between cheaper heavily-genericized products such as methotrexate and cyclosporine, and novel biologic products, such as Wyeth and Amgen's Enbrel and Centocor's Remicade, which are expensive and injectable but provide a much more targeted therapy.
		On the downside, the liver side-effects associated with Arava have received attention with a Public Citizen petition launched against it in 2004.
	www.pharmaceutical-business-review.com /article_feature.asp?guid=0EFE234D-D6F8-495D-B615-908F0AE2D680 (451 words)

	Jandrugs \| Arava Buy Arava side effects information cheap Arava from Canadian Online Pharmacy at discounted rates!
		Arava (Leflunomide) is a drug that is primarily used for the treatment of Arthritis.
		Arava (Leflunomide) is generally recommended to be taken once a day and may be taken with or without food with a glass full of water.
		Arava (Leflunomide) should not be taken if one has or has had a liver problem, as Arava may increase the risk of such kind of diseases.
	www.jandrugs.com /momex/NavCode/druginfo.arava (1041 words)

	Irwin & Boesen - Denver, Colorado Trial Attorneys - Arava
		Arava (leflunomide) is the first oral treatment approved for slowing the progression of rheumatoid arthritis.
		Although its effects are similar to those of methotrexate, this drug works by a different chemical mechanism that blocks at least one enzyme in certain immune cells called lymphocytes (a type of white blood cell that is part of the immune system), and thereby retards the progression of the disease.
		However, Arava is not a cure for rheumatoid arthritis.
	www.irwin-boesen.com /areas/arava.htm (421 words)

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