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	Aripiprazole (Abilify)
		Aripiprazole is greater than 99% bound to protein (primarily albumin) and has a half-life of approximately 75 hours in extensive metabolizers.
		Aripiprazole's effect on cardiac function is unknown in patients with a recent myocardial infarction or unstable heart disease; therefore caution should be used in these patients.
		Aripiprazole may impair cognitive and motor function secondary to causing somnolence, therefore proper precautions should be implemented.
	uuhsc.utah.edu /pharmacy/bulletins/aripiprazole.html (669 words)

	Aripiprazole ( Abilitat ) (Site not responding. Last check: 2007-10-12)
		In patients with acute relapse of schizophrenia or schizoaffective disorder, aripiprazole 15 to 30 mg/day was at least as effective as haloperidol 10 mg/day and had similar efficacy to risperidone 6 mg/day in well designed, 4-week, placebo-controlled trials.
		Aripiprazole was superior to placebo in a 26-week trial in patients with stable, chronic schizophrenia.
		In a 52-week trial involving patients with acute relapsing disease, aripiprazole was similar to haloperidol as assessed by time to failure to maintain response and was superior in ameliorating negative and depressive symptoms.
	www.biopsychiatry.com /aripip.html (222 words)

	NAMI \| Abilify (aripiprazole)
		Aripiprazole is an "atypical" antipsychotic medication approved for the treatment of schizophrenia by the FDA in 2002.
		Aripiprazole helps manage positive symptoms (e.g., hallucinations, delusions, and thought disturbances) as well as negative symptoms (e.g., social withdrawal, inability to experience pleasure, and blunted affect) of schizophrenia.
		If a dose of aripiprazole is missed, take it as soon as you remember it, if it is not too close to when your next dose is due—discuss this with your health care provider.
	www.nami.org /Template.cfm?Section=About_Medications&template=/ContentManagement/ContentDisplay.cfm&ContentID=8133 (1065 words)

	aripiprazole - Hartford, Connecticut CT
		Aripiprazole is not for use in psychotic conditions that are related to dementia.
		Aripiprazole is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder (manic depression).
		Aripiprazole oral solution should be stored in the refrigerator and can be used for up to 6 months after opening.
	www.saintfranciscare.com /111117.cfm (1412 words)

	Online, Description, Chemistry, Ingredients, Blackbox - Aripiprazole - RxList Monographs
		Although the causes of death were varied, most of the deaths appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature.
		ABILIFY (aripiprazole) is not approved for the treatment of patients with dementia-related psychosis.
		(aripiprazole) orally disintegrating tablets, and in solution for oral administration.
	www.rxlist.com /cgi/generic/abilify.htm (324 words)

	Aripiprazole
		Aripiprazole is not approved by the FDA for use in the treatment of behavioral disorders in older adults with dementia.
		Aripiprazole is used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions).
		It is also used to treat episodes of mania (frenzied, abnormally excited or irritated mood) or mixed episodes (symptoms of mania and depression that happen together) in patients with bipolar I disorder (manic depressive disorder; a disease that causes episodes of depression, episodes of mania, and other abnormal moods).
	www.safemedication.com /displaydrug.cfm?id=603012 (1033 words)

	Aripiprazole: abilify aripiprazole
		Aripiprazole was discovered in Japan by Otsuka Phramaceutical Co., Ltd. The compound entered Phase II trials for patients with schizophrenia in that country by 1995, followed by Phase III trials in Europe by 2000.
		The physician may chose to use aripiprazole if he or she feels that it its benefits outweigh this potential concern.
		Aripiprazole is not recommended during breast-feeding, because it may cause unwanted effects in nursing babies.
	www.depression-guide.com /aripiprazole.htm (613 words)

	aripiprazole (Abilify) - drug class, medical uses, medication side effects, and drug interactions by MedicineNet.com
		The FDA approved aripiprazole as a treatment for schizophrenia in November of 2002.
		The manufacturer recommends that patients on aripiprazole who are started on carbamazepine double their dose of aripiprazole, under their doctor's supervision.
		NURSING MOTHERS: It is not known if aripiprazole is excreted in breast milk; however, since most medicines are excreted in breast milk, it is recommended that women receiving aripiprazole should not breast feed.
	www.medicinenet.com /aripiprazole/article.htm (832 words)

	Aripiprazole
		Aripiprazole appears to mediate its antipsychotic effects primarily by partial agonism at the D2 receptor.
		Partial agonism at D2 receptors has been shown to modulate dopaminergic activity in areas where dopamine activity may be high or low, such as the mesolimbic and mesocortical areas of the schizophrenic brain, respectively.
		Aripiprazole has moderate affinity for histamine and alpha adrenergic receptors, and no appreciable affinity for cholinergic muscarinic receptors.
	www.bipolarworld.net /Medications/Antipsychotics/antipsy6.htm (334 words)

	Overdose, Contraindications and Information - Aripiprazole - RxList Monographs
		Included in the 76 cases are 10 cases of deliberate or accidental overdosage in children (age 12 and younger) involving aripiprazole ingestions up to 195 mg with no fatalities.
		Common adverse events (reported in at least 5% of all overdose cases) reported with aripiprazole overdosage (alone or in combination with other substances) include vomiting, somnolence, and tremor.
		Hemodialysis: Although there is no information on the effect of hemodialysis in treating an overdose with aripiprazole, hemodialysis is unlikely to be useful in overdose management since aripiprazole is highly bound to plasma proteins.
	www.rxlist.com /cgi/generic/abilify_od.htm (328 words)

	Aripiprazole - Drugs & Vitamins - Drug Library - DrugDigest (Site not responding. Last check: 2007-10-12)
		Aripiprazole can help you to keep in touch with reality and reduce your other symptoms.
		Occasionally aripiprazole is used to treat other mood disturbances.
		Aripiprazole can reduce the response of your body to heat or cold.
	www.drugdigest.org /DD/DVH/Uses/0,3915,551514\|Aripiprazole,00.html (595 words)

	ClinicalTrials.gov - Information on Clinical Trials and Human Research Studies: Trial List
		Aripiprazole in Children and Adolescents With Bipolar Disorder and ADHD
		Aripiprazole Associated With Methylphenidate in Children and Adolescents With Bipolar Disorder and ADHD
		A Study of Aripiprazole in Children and Adolescents With Aspergers and Pervasive Developmental Disorder.
	clinicaltrials.gov /search/intervention=Aripiprazole (519 words)

	FDA Public Health Advisory: Deaths with Antipsychotics in Elderly Patients with Behavioral Disturbances
		The Food and Drug Administration has determined that the treatment of behavioral disorders in elderly patients with dementia with atypical (second generation) antipsychotic medications is associated with increased mortality.
		Of a total of seventeen placebo controlled trials performed with olanzapine (Zyprexa), aripiprazole (Abilify), risperidone (Risperdal), or quetiapine (Seroquel) in elderly demented patients with behavioral disorders, fifteen showed numerical increases in mortality in the drug-treated group compared to the placebo-treated patients.
		These studies enrolled a total of 5106 patients, and several analyses have demonstrated an approximately 1.6-1.7 fold increase in mortality in these studies.
	www.fda.gov /cder/drug/advisory/antipsychotics.htm (338 words)

	Aripiprazole for schizophrenia: Systematic review -- El-Sayeh et al. 189 (2): 102 -- The British Journal of Psychiatry
		Background Aripiprazole is an atypical antipsychotic that is
		aripiprazole treatment was associated with a significant decrease
		Aripiprazole for Schizophrenia, El-Sayeh et al British Journal of Psychiatry 2006;189:102—108.
	bjp.rcpsych.org /cgi/content/abstract/189/2/102 (285 words)

	MedlinePlus Drug Information: Aripiprazole
		Continue to take aripiprazole even if you feel well.
		This is more common when you first start taking aripiprazole.
		Tell your doctor if you plan to do vigorous exercise or be exposed to extreme heat.
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a603012.html (1130 words)

	Aripiprazole, Discount Aripiprazole - XLPharmacy
		Abilify, Generic Abilify, Aripiprazole is an antipsychotic medication and works by changing the actions of chemicals in the brain.
		Abilify, Generic Abilify, Aripiprazole is used to treat the symptoms of schizophrenia.
		Do not stop taking Abilify, Generic Abilify, Aripiprazole without first talking to your doctor, even if you are feeling well.
	www.xlpharmacy.com /productDesc.php?prodid=148&prodattid=1280 (138 words)

	Aripiprazole ( Abilify, Abilitat )
		Moreover, in contrast to classical antipsychotics that produce disabling movement disorders, aripiprazole does not cause an upregulation of D2 receptors or an increase in expression of the c-fos mRNA in the striatum, in agreement with the low risk for extrapyramidal side effects (EPS) during aripiprazole treatment [245781], [262096], [350481], [350483].
		Collectively, aripiprazole is an important atypical antipsychotic candidate with a favorable safety profile.
		Moreover, the mechanism of action of aripiprazole differentiates it from both typical and atypical antipsychotics and hence, may provide important leads for pharmacotherapy of schizophrenia and other psychotic disorders.
	www.biopsychiatry.com /aripiprazole.html (282 words)

	Newly Approved Drug Therapies (829): Abilify (aripiprazole), Bristol-Myers Squibb, Otsuka America Pharmaceutical
		Abilify (aripiprazole) is an orally administered drug approved in November 2002 for the treatment of schizophrenia.
		No evidence of clinical superiority was shown by the higher doses compared to the lowest dose.
		No siginficant differences were found in incidence of discontinuation due to adverse events experienced by the aripiprazole group compared to the placebo group.
	www.centerwatch.com /patient/drugs/dru829.html (406 words)

	Effectiveness of aripiprazole v. haloperidol in acute bipolar mania: Double-blind, randomised, comparative 12-week ...
		Method Patients (n=347) were randomised to receive aripiprazole
		Aripiprazole reduces acute mania compared with haloperidol in bipolar I disorder and causes fewer adverse effects.
		Aripiprazole- potential for worsening psychosis and agitation- caution for use in mania?
	bjp.rcpsych.org /cgi/content/abstract/187/3/235 (325 words)

	APA Division of Psychopharmacology and Substance Abuse
		The APA convention was held on August 10–13 in New Orleans.
		Title: The Discriminative-Stimulus Effects of d-Amphetamine: Influence of Aripiprazole Pretreatment.
		Title: Drug Reinforcement: Using Laboratory and Clinical Models to Investigate.
	www.apa.org /divisions/div28/index.html (468 words)

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	MedWatch - Zyprexa (olanzapine) Dear Doctor Letter
		The Food and Drug Administration (FDA) has asked all manufacturers of atypical antipsychotic medications, including Lilly, to add a Warning statement describing the increased risk of hyperglycemia and diabetes in patients taking these medications, including Zyprexa.
		In addition to Zyprexa, the atypical antipsychotic class includes Clozaril ®; (clozapine, Novartis), Risperdal ® (risperidone, Janssen), Seroquel ® (quetiapine, AstraZeneca), Geodon ® (ziprasidone, Pfizer), and Abilify ®; (aripiprazole, Bristol Myers Squibb and Otsuka American Pharmaceutical).
		Accordingly, the Zyprexa prescribing information has been updated with the following information:
	www.fda.gov /medwatch/SAFETY/2004/zyprexa.htm (448 words)

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