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| | Karger Publishers |
 | | [45, 46] succeeded in isolation of the renal afferent and efferent arterioles, with an attached glomerulus and a thick ascending limb of Henle loop. |
 | | In the efferent arteriole, we have recently demonstrated that during the angiotensin II stimulation, both PKC- and IP3-associated vasoconstrictor mechanisms are activated in an additive manner [74, 75]. |
 | | Although amlodipine predominantly dilates the afferent arteriole in the isolated perfused hydronephrotic kidney [15], this antagonist is also reported to cause a substantial dilation of efferent, as well as afferent, arterioles in the in vivo hydronephrotic kidney [86]. |
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