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Topic: Aseptic bone necrosis

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Guelph Platers

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	Aseptic Bone Necrosis
		Aseptic necrosis is a condition where there is death and degeneration of bone which appears to relate to stenosis of the draining veins.
		Aseptic necrosis is a painful and disabling condition.
		In cases of aseptic necrosis of the hips surgical replacement may be necessary.
	www.burtonreport.com /InfSpine/EpiduralSteroidAsepticNecrosis.htm (295 words)

	Aseptic bone necrosis - Wikipedia, the free encyclopedia
		Aseptic bone necrosis (ABN), also called avascular necrosis or osteonecrosis, is where bone and marrow die in the absence of an infective agent.
		Necrosis in the epiphysis or in the bone joints, which extends into adjacent cartilage is more serious.
		But new bone is soft, may misshape or fracture under pressure producing malformed joint surfaces and hence pain and mobility problems, afflictions such as arthritis.
	en.wikipedia.org /wiki/Aseptic_bone_necrosis (425 words)

	Necrosis - Wikipedia, the free encyclopedia
		Necrosis (in Greek Νεκρός = Dead) is the name given to unprogrammed death of cells and living tissue.
		Necrosis is caused by special enzymes that are released by lysosomes which are capable of digesting cell components or the entire cell itself.
		Haemorrhagic necrosis – is due to blockage of the venous drainage of an organ or tissue and occurs in testicular torsion.
	en.wikipedia.org /wiki/Necrosis (432 words)

	THE MERCK MANUAL, Sec. 5, Ch. 53, Avascular Necrosis
		Posttraumatic avascular necrosis develops when blood supply is impaired and is thus a function of the relative contributions of arteries to the femoral or humeral head and the extent of anastomoses between them, which varies among persons.
		Avascular necrosis of the knee in the elderly is almost always associated with sudden atraumatic onset of severe constant pain localized to the medial aspect of the knee, accompanied by tenderness over the medial femoral condyle and, in 1/3 of patients, mild to moderate effusion.
		This is followed by collapse of the bone (flattening of the femoral head) and finally by narrowed joint space and osteoarthritic changes in the opposing bones of the joint.
	www.merck.com /pubs/mmanual/section5/chapter53/53a.htm (1055 words)

	Chinese Medicine Introduction of curing femoral Head Necrosis and Aseptic Necrosis of Femoral Head
		A: Femoral head necrosis is one kind of common osteopathy with multiple etiological factors and complicated pathogenesis and high incidence.
		A: Osteolytic femoral head necrosis, collapsed femoral head necrosis, constrictive femoral head necrosis, hypertrophic femoral head necrosis, rigid femoral head necrosis and femoral head necrosis of supermicrostructure dissociation.
		Femoral head necrosis results from local ischemia induced by varieties of factors and series of change which includes decrease of muscle contraction power and joint dysfunction etc will ensue owing to limited mobilization because of pain after necrosis.
	www.axmz.com /medicine.html (1426 words)

	[No title]
		The compact bone has high density and it is composed of concentric layers of bone tissue with a channel in the center where blood vessels, lymphatic vessels and nerves longitudinally traverse the bone.
		Osteomalacia (softening of bones in grown animals) is the same disease as rickets; however, this metabolic bone disease occurs in grown animals whose growth plates have already closed.
		Osteodystrophia Fibrosa (Fibrous osteodystrophy): It is a metabolic bone disease characterized by increased osteoclastic resorption of bone and replacement by fibrous connective tissue.
	people.upei.ca /lopez/bone-notes.htm (2591 words)

	Avascular Necrosis
		Avascular necrosis is a disease resulting from the temporary or permanent loss of the blood supply to the bones.
		The goal in treating avascular necrosis is to improve the patient's use of the affected joint, stop further damage to the bone, and ensure bone and joint survival.
		Bone grafting is surgery that transplants healthy bone from one part of the patient, such as the leg, to the diseased area.
	healthlink.mcw.edu /article/926046182.html (2000 words)

	Osteonecrosis
		By convention, the terms "aseptic" or "avascular" necrosis have been applied to areas of juxtaarticular involvement and the term bone infarct is usually applied to metaphyseal or diaphyseal involvement.
		As living bone reacts to the presence of adjacent dead bone, a thick sclerotic zone may develop along the "no-man's land" between the living and necrotic bone.
		The classic MR appearance of osteonecrosis is that of a segmental area of low signal intensity in the subchondral bone, bounded by a low signal intensity border.
	www.rad.washington.edu /mskbook/osteonecrosis.html (1863 words)

	Avascular Necrosis on Bone Scan (Site not responding. Last check: 2007-11-02)
		There are 2 major forms of bone infarction: 1- Medullary bone infarction which involves the trabecular architecture and marrow cavity and is usually clinically silent; and 2- Corticomedullary infarction which is typically subchondral, painful, and classically involves the femoral or humeral heads.
		Bone marrow scanning is more sensitive than bone scan for the detection of bone infarction/aseptic necrosis.
		Radiation damage to bone is primarily mediated by alterations in the microvasculature.
	www.indyrad.iupui.edu /public/lectures/HTML/nm/bone/BONE05.HTM (1432 words)

	Aseptic necrosis
		Aseptic necrosis is bone death caused from a disruption in the blood supply.
		Aseptic necrosis results when part of the boneÂ does not receive blood and dies.
		Aseptic necrosis can be caused by an underlying disease, orÂ a severeÂ trauma, such as a break or dislocation, that affects the blood supply to the bone.Â Many times, no trauma or disease is present.
	www.umm.edu /ency/article/007260.htm (392 words)

	Template
		Freiberg's disease is the only bone necrosis that is more often seen in girls than in boys.
		Condensation-density of bone structures in hypermineralization of necrotic bony trabecula.
		Aseptic bone necrosis are seen in children along with cartilage ossification defects throughout growth or throughout increased exertion.
	www.e-radiography.net /radpath/f/freibergs.htm (190 words)

	Aseptic Necrosis - Heart Disease and other cardiovascular conditions on MedicineNet.com
		Aseptic necrosis (also referred to as avascular necrosis or osteonecrosis) is a bone condition that results from poor blood supply to an area of bone causing bone death.
		Conditions that are associated with aseptic necrosis include alcoholism, cortisone medications, Cushing's syndrome, radiation exposure, sickle cell disease, pancreatitis, Gaucher disease, and systemic lupus erythematosus.
		The treatment of aseptic necrosis is critically dependent on the stage of the condition.
	www.medicinenet.com /aseptic_necrosis/article.htm (660 words)

	Bone Disorders - Avascular Necrosis
		Although avascular necrosis may affect both genders and all age groups, it is diagnosed most often in persons in their 30s and 40s.
		The goal of treatment for avascular necrosis is to improve functionality or to stop further damage to the affected bone or joint.
		bone graft - a surgical procedure in which healthy bone is transplanted from another part of the patient's body into the affected area.
	uuhsc.utah.edu /healthinfo/adult/bone/avascul.htm (729 words)

	About Osteonecrosis
		One approach to this problem is to surgically remove the dead bone and fill the empty space with bone graft that is either taken from the patient or from the bone bank.
		The dead bone is removed from the femoral head and replaced with the grafted bone that carries with it it's own blood supply.
		Bone graft substitutes and electrical stimulation are being studied in select centers throughout the country.
	www.aboutjoints.com /patientinfo/topics/osteonecrosis/Osteonecrosis.html (4754 words)

	Sickle Cell - Health and Medical Information produced by doctors - MedicineNet.com
		Aseptic Necrosis and Bone Infarcts (death of portions of bone)
		Dactylitis is caused by injury to the bones of the affected digits by repeated episodes of inadequate blood circulation.
		Aseptic necrosis, or localized bone death, is a result of inadequate oxygen supply to the bone.
	www.medicinenet.com /sickle_cell/page3.htm (2349 words)

	MedlinePlus Medical Encyclopedia: Aseptic necrosis
		If the reason for the development of aseptic necrosis is known, part of the treatment will be aimed at the underlying condition.
		Prognosis depends on the stage of the disease at the time it was diagnosed; the size of the area of bone involved; whether any underlying conditions contributed to the condition; and the age and general health of the person affected.
		Advanced aseptic necrosis can lead to osteoarthritis and permanent decreased mobility. Severe cases of osteoarthritis may require joint replacement.
	www.nlm.nih.gov /medlineplus/ency/article/007260.htm (884 words)

	Long-term Effects of Sport Diving
		The incidence of avascular necrosis in the general population is unknown, so the alternative causes of bone necrosis should be excluded when the condition is found in divers.
		It was used in 1981 by the Decompression Sickness Registry, who found that the percentage of bone necrosis, both shaft and juxta-articular, increases in a sample of divers with age and experience.
		Necrosis was not found in those who had never dived deeper than 30 meters, but was detected in 30 out of 190 men (15.8%) who had dived deeper than 200 meters.
	www.scuba-doc.com /LTE.htm (5963 words)

	eMedicine - Bone Infarct : Article Excerpt by: Ali Nawaz Khan, MBBS, FRCP, FRCR (Site not responding. Last check: 2007-11-02)
		Ischemic cell death and necrosis is the result of a reduced blood supply to the bone, which in turn can be due to either an intrinsic or extrinsic abnormality in the blood vessel supplying part of the bone or a combination of both.
		Minor differences appear in the patterns of response for juxta-articular bone necrosis, but the pattern and sequence of events are similar to those of medullary necrosis.
		Beneath the articular cartilage in juxta-articular necrosis, the depth of the yellow necrotic marrow varies, and bone trabeculae are devoid of osteocytes.
	www.emedicine.com /radio/byname/bone-infarct.htm (595 words)

	Colorado Springs Orthopaedic Group (Site not responding. Last check: 2007-11-02)
		Although the specific cause of the bone death is not precisely known except in the case of fracture, a number of conditions have been associated with ON.
		One of the ways that can cause the bone to heal is to surgically remove the dead bone and fill the empty space with bone graft that is either taken from the patient or from the bone bank.
		For this procedure, a bone with its blood vessels is taken from the patient and hooked up to blood vessels near the hip.
	www.csorthopedics.com /pages/patient.php?topic=osteonecrosis (2210 words)

	eSynopsis of Avascular Necrosis of the Bone
		•Fractures, thrombosis and embolism, injury of vessels due to vasculitis, and hypertension are all associated with bone infarcts.
		•As with necrosis due to any cause, avascular necrosis of bone is recognized by the absence of cells in lacunae.
		•Necrosis of the marrow space resembles fat necrosis elsewhere and is typified by the presence of bluish, acellular material.
	esynopsis.uchc.edu /S508.htm (189 words)

	Aseptic bone necrosis in an amateur scuba diver -- Laden and Grout 38 (5): e19 -- British Journal of Sports Medicine
		Aseptic bone necrosis in an amateur scuba diver
		Figure 1 Plain radiograph of left shoulder, showing established avascular bone necrosis of the proximal humerus with collapse of the articular surface.
		The role of decompression inadequacy in aseptic bone necrosis of naval divers.
	bjsm.bmjjournals.com /cgi/content/full/38/5/e19 (1060 words)

	Bone (nontumor and tumor)
		Fibrous/fibroosseous tumors of bone: cortical irregularities of femur,
		Bone Histomorphometry: measuring bone formation (% active osteoblastic surface, % osteoid surface, % mineralizing surface), bone mineralization (osteoid volume, mineral apposition rate), bone resorption (% total eroded surface, % active osteoclastic surface). Bone resorption is identified by numerous osteoclasts in Howship’s lacunae and in bone margins
		Bones are classified based on embryologic development as endochondral (formed by ossification of cartilaginous anlage, such as long bones) and membranous (formed from connective tissue, such as skull)
	pathologyoutlines.com /bone.html (3394 words)

	Avascular Necrosis of the Talus: A Pictorial Essay -- Pearce et al. 25 (2): 399 -- RadioGraphics
		Avascular necrosis (AVN) is bone death due to ischemia.
		On the external aspect of the arch of fibrosis, there are coarser, thicker trabeculae, indicating that this area of the bone is viable and is capable of reaction.
		The bone trabeculae on the viable (tibial) side show smooth endosteal contours (white arrows); the adipose tissue of the bone marrow shows a fine filiform pattern (white arrowheads).
	radiographics.rsnajnls.org /cgi/content/full/25/2/399 (5640 words)

	Avascular Necrosis of the Femoral Head
		Avascular necrosis (also referred to as aseptic necrosis or osteonecrosis) is a condition that results from poor blood supply to an area of bone causing bone death.
		Other causes of poor blood circulation to the bone include an embolism of air or fat that blocks the blood flow through the blood vessels, abnormally thick blood (hypercoaguable state), and inflammation of the blood vessel walls (vasculitis).
		Conditions that are associated with aseptic necrosis include alcoholism, steroid usage, Cushing's syndrome, radiation exposure, sickle cell disease, pancreatitis, Gaucher's disease, and systemic lupus erythematosus.
	www.pitt.edu /~antonp/Welcome.html (360 words)

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