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Topic: Aspartate transaminase

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	[No title]
		The fate of the precursor to mitochondrial aspartate aminotransferase.
		Aspartate aminotransferase from S. solfataricus is cleaved at residue 28 by thermolysin and residues 32 and 33 by trypsin; analogously, pig heart cytosolic aspartate aminotransferase is cleaved at residues 19 and 25 [Iriarte, A., Hubert, E., Kraft, K. & Martinez-Carrion, M. Biol.
		In the case of aspartate aminotransferase from S. solfataricus, proteolytic cleavages also result in transaminase inactivation thus indicating that both enzymes, although evolutionarily distinct, possess a region involved in catalysis and well exposed to proteases which is similarly positioned in their primary structure.
	cbmc.umh.es /practicas/LIIB/Pr16/refmedline.txt (9525 words)

	Liver function tests - Wikipedia, the free encyclopedia
		Alanine transaminase (ALT), also called Serum Glutamic Pyruvic Transaminase (SGPT) or Alanine aminotransferrase (ALAT) is an enzyme present in hepatocytes (liver cells).
		It is dangerous in babies, as it can pass the blood-brain barrier causing kernicterus.
		Aspartate transaminase (AST) also called Serum Glutamic Oxaloacetic Transaminase (SGOT) or aspartate aminotransferase (ASAT) is similar to ALT in that it is another enzyme associated with liver parenchymal cells.
	en.wikipedia.org /wiki/Liver_enzyme (643 words)

	Liver Function Tests
		Alanine transaminase is an enzyme that is important in the processing of proteins.
		Aspartate transaminase is an enzyme that plays a role in many aspects of body metabolism.
		Compared to the transaminases, alkaline phosphatase tends to be higher in diseases associated with injury to the bile-secreting part of the liver's activity.
	www.kidshealth.org /PageManager.jsp?dn=poehealth&lic=111&ps=107&cat_id=20044&article_set=22795 (804 words)

	Alanine transaminase - Open Encyclopedia (Site not responding. Last check: 2007-10-21)
		Alanine transaminase or ALT is (mostly) a liver enzyme.
		It is also called Serum Glutamic Pyruvic Transaminase (SGPT) or Alanine aminotransferrase (ALAT) The spillover of this enzyme into blood is routinely measured as a marker of liver-cell damage.
		The enzyme aspartate transaminase (AST) has a similar role, but this enzyme tends to be found in other tissues, such as the heart, so is not as specific to the liver.
	www.open-encyclopedia.com /Alanine_transaminase (105 words)

	Principles of Biochemistry, 3rd Edition CW Chapter 17 -- Practice Exercises III (Site not responding. Last check: 2007-10-21)
		Aspartate beta-semialdehyde is acetylated to prevent ring closure.
		Aspartate beta-semialdehyde branches do form several compounds; therefore, it is probably swept up into other biosynthetic pathways as soon as it is formed.
		The transport of aspartate or glutamate would rob the citric-acid cycle of key intermediates necessary for respiration.
	cwx.prenhall.com /horton/chapter17/multiple3/deluxe-content.html (383 words)

	Transaminase
		Non-English Usage: "Transaminase" is also a word in the following languages with English translations in parentheses.
		"Transaminase" is generally used as a noun (singular) -- approximately 100.00% of the time.
		"Transaminase" is used about 17 times out of a sample of 100 million words spoken or written in English.
	www.websters-online-dictionary.org /definition/english/Tr/Transaminase.html (452 words)

	International Conference on Psychophysiology of Panic Attacks (Site not responding. Last check: 2007-10-21)
		It is understood that transaminases and alkaline phosphatase levels are increased during panic attacks.
		This study examines the influence of examination stress during panic situation, on Aspartate transaminase, Alanine transaminase and alkaline phosphatase among students.
		Aspartate transaminase and alanine transaminase enzymes were assayed by the method King (1965).
	anxiety-panic.com /conference/c004ah.cfm (302 words)

	Glud1 - Glutamate dehydrogenase 1, mitochondrial precursor (Site not responding. Last check: 2007-10-21)
		The increase in photodamage is greater for the cytosolic and mitochondrial enzymes lactate dehydrogenase and glutamate dehydrogenase and least for the lysosomal enzymes beta-glucuroninidase and N-acetyl-beta-glucosaminidase.
		Livers were assayed for: isocitrate dehydrogenase, glutamate dehydrogenase, lactate dehydrogenase, alcohol dehydrogenase, glutathione reductase, glyoxylate reductase, L-alanine aminotransferase, glutamate oxalacetate transaminase, pyruvate decarboxylase, fructose-1-phosphate aldolase, fructose diphosphate aldolase, fructose 1,6-diphosphatase, and fatty acid synthetase.
		Differential digitonin extraction of rat liver mitochondria and of mitochondria of livers of affected and unaffected male sparse fur mice released a lysine transcarbamylase activity from the mitochondria at a digitonin to protein ratio in between that for myokinase and glutamate dehydrogenase, but at a slightly lower ratio than the ornithine transcarbamylase activity.
	www.ihop-net.org /UniPub/iHOP/gg/121313.html (1746 words)

	MedFriendly.com: Aspartate aminotransferase (Site not responding. Last check: 2007-10-21)
		Aspartate aminotransferase (commonly abbreviated AST) is a type of enzyme.
		A vitamin is one of a group of substances made up partly of carbon (an element) that are essential in small amounts for normal bodily functioning and chemical processes in the body to take place.
		Aspartate aminotransferase is also known as glutamic-oxaloacetic transferase (GOT), serum glutamic-oxaloacetic transferase (SGOT), aspartate transaminase, and glutamic-aspartic transaminase.
	www.medfriendly.com /aspartateaminotransferase.html (1515 words)

	PRINTS Search
		Aspartate aminotransferase is important for the metabolism of amino acids and Krebs-cycle related organic acids.
		TRANSAMINASE is a 6-element fingerprint that provides a signature for aspartate aminotransferases.
		AATC_DAUCA ASPARTATE AMINOTRANSFERASE, CYTOPLASMIC (EC 2.6.1.1) (TRANSA AAT3_ARATH ASPARTATE AMINOTRANSFERASE, CHLOROPLAST PRECURSOR (EC 2.6.1.
	www.enzim.hu /~szia/bioinformatika/ea05/prints.htm (532 words)

	Caloric restriction increases gluconeogenic and transaminase enzyme activities in mouse liver. (Site not responding. Last check: 2007-10-21)
		We investigated the activities of gluconeogenic and transaminase enzymes in the livers of old and young mice fed either control or calorie-restricted diets.
		Increased activities of tyrosine, tryptophan, histidine, phenylalanine, alanine and aspartate transaminases, as well as of malate and glutamate dehydrogenases were also observed, while branched-chain amino acid transaminase was unchanged.
		Young mice on CR showed a significant increase only in the phosphoenolpyruvate carboxykinase activity in the gluconeogenic pathway, while transaminases were increased significantly, except for tryptophan and branched-chain amino acid transaminases.
	www.arclab.org /medlineupdates/abstract_12581790.html (217 words)

	OUTPUT from blastx for 5009-0-44-G02 (Site not responding. Last check: 2007-10-21)
		>spP52894ALA2_HORVU ALANINE AMINOTRANSFERASE 2 (GPT) (GLUTAMIC--PYRUVIC TRANSAMINASE 2) (GLUTAMIC--ALANINE TRANSAMINASE 2) (ALAAT-2) pirS42535 alanine transaminase (EC 2.6.1.2) - barley embCAA81231.1
		>spP34106ALA2_PANMI ALANINE AMINOTRANSFERASE 2 (GPT) (GLUTAMIC--PYRUVIC TRANSAMINASE 2) (GLUTAMIC--ALANINE TRANSAMINASE 2) (ALAAT-2) pirS28429 alanine transaminase (EC 2.6.1.2) - proso millet embCAA49199.1
		>pirT08064 alanine transaminase (EC 2.6.1.2) - Chlamydomonas reinhardtii gbAAB01685.1
	cbr-rbc.nrc-cnrc.gc.ca /reith/tetra/tetra5/5009-0-44-G02.html (407 words)

	Media Portfolio (Site not responding. Last check: 2007-10-21)
		Cytosolic aspartate transaminase from pig heart is a dimer of identical subunits (individual monomers are shown in purple and blue).
		All known transaminases require the coenzyme pyridoxal phosphate and all have ping-poing kinetic mechanisms.Aspartate transaminase catalyzes the transfer of an amino group from glutamate to oxaloacetate, forming alphaketoglutarate and aspartate.
		When aspartate is in excess, the amino groups are used to make free ammonia that enter the urea cycle as carbamoyl phosphate.
	cwx.prenhall.com /horton/medialib/media_portfolio/17.html (1152 words)

	[No title] (Site not responding. Last check: 2007-10-21)
		54 4e-06 PIR:D75496 aspartate transaminase (EC 2.6.1.1) DR0623 [similarit...
		52 1e-05 PIR:C97876 aspartate transaminase (EC 2.6.1.1) [imported] - Stre...
		50 4e-05 PIR:G72655 aspartate transaminase (EC 2.6.1.1) APE0674 [similari...
	pedant.gsf.de /cgi-bin/wwwdbp.pl?Db=Saccharomyces_cerevisiae&Name=blast&String=3078&Cmd=Fetch (1916 words)

	Amino Acid Metabolism
		The former catalyzed by glutamate dehydrogenase and the latter by aspartate aminotransferase, AST.
		The importance of glutamate as a common intracellular amino donor for transamination reactions and of aspartate as a precursor of ornithine for the urea cycle is described in the Nitrogen Metabolism page.
		Glutamate and aspartate are important in collecting and eliminating amino nitrogen via glutamine synthetase and the urea cycle, respectively.
	web.indstate.edu /thcme/mwking/amino-acid-metabolism.html (3753 words)

	Effect of the dietary fatty acid component on the release of 14C-taurocholate, 14C-bilirubin, alkaline phosphatase, and ...
		Effect of the dietary fatty acid component on the release of 14C-taurocholate, 14C-bilirubin, alkaline phosphatase, and aspartate transaminase by isolated rat liver cells -- Anderson et al.
		Effect of the dietary fatty acid component on the release of 14C-taurocholate, 14C-bilirubin, alkaline phosphatase, and aspartate transaminase by isolated rat liver cells
		The release from isolated cells of alkaline phosphatase and aspartate transaminase during a 3-hr incubation did not differ.
	jpen.aspenjournals.org /cgi/content/abstract/9/4/477 (296 words)

	UPC Diagnosis Series - Evaluating Abnormal Test Results - TRANSAMINASES - Hennes et al. (Site not responding. Last check: 2007-10-21)
		Elevated liver transaminase levels in children with blunt abdominal trauma: a predictor of liver injury.
		Elevated serum transaminase levels (AST greater than 450 IU/L and ALT greater than 250 IU/L) identified all of the patients with hepatic injury visible on abdominal CT scan.
		The sensitivity and specificity of elevated serum transaminase levels were 100% and 92.3%, respectively, for predicting hepatic injury.
	www.medicine.uiowa.edu /Path_Handbook/upcmd/01225/abs_hennes90.html (247 words)

	At2g30970 - Aspartate aminotransferase, mitochondrial precursor (Site not responding. Last check: 2007-10-21)
		At2g30970 is a homologue of At4g31990 (Aspartate aminotransferase, chloroplast precursor) from Arabidopsis thaliana.
		At2g30970 is a homologue of At5g11520 (Aspartate aminotransferase, chloroplast precursor) from Arabidopsis thaliana.
		At2g30970 is a homologue of Got2 (Aspartate aminotransferase, mitochondrial precursor) from Mus musculus.
	www.pdg.cnb.uam.es /UniPub/iHOP/gg/3026.html (262 words)

	Human protein: P17174 - Aspartate aminotransferase, cytoplasmic (EC ) (Transaminase A) (Glutamate oxaloacetate ...
		Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively.
		Upstream genomic sequence for Glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
		The amino acid sequence of cytosolic aspartate aminotransferase from human liver.
	harvester.embl.de /harvester/P171/P17174.htm (737 words)

	Mouse protein: P05201 - Aspartate aminotransferase, cytoplasmic (EC ) (Transaminase A) (Glutamate oxaloacetate ...
		Mouse protein: P05201 - Aspartate aminotransferase, cytoplasmic (EC) (Transaminase A) (Glutamate oxaloacetate transaminase 1).
		Aspartate aminotransferase, cytoplasmic (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 1).
		Introns antedate the divergence of cytosolic and mitochondrial isoenzyme genes.
	marvester.embl.de /marvester/P052/P05201.htm (632 words)

	Tables
		Alanine transaminase (units/L) Aspartate transaminase (units/L) Alkaline phosphatase (units/L) Lactate dehydrogenase (units/L) b
		Alanine transaminase (units/L) Aspartate transaminase (units/L) -glutamyl transferase (units/L) Alkaline phosphatase (units/L) c
		Normal values: alanine transaminase, 0-35 units/ L; aspartate transaminase, 0-35 units/L; alkaline phosphatase, 30-114 units/L; lactate dehydrogenase, 118-242 units/L; total bilirubin, <1.2 mg/dL; direct bilirubin, <0.2 mg/dL;
	www.medscape.com /content/2002/00/44/02/440227/440227_tab.html (152 words)

	Hepatitis Central, A prospective, Community Based Evaluation of Liver Enzymes in individuals with Hepatitis C after ...
		Long-term elevation in serum transaminases, especially alanine transaminase (ALT), was once the principal indication of persistent HCV infection, formerly called non-A, non-B hepatitis.
		These limitations notwithstanding, serum transaminase measurements are inexpensive, safely obtained, and readily available, and continue to be widely used in the management of HCV infection.
		Given that ALT is the transaminase measurement widely accepted and used in studies of treatment and outcomes in HCV infection, ALT was used solely in the rest of the analysis.
	www.hepatitis-central.com /hcv/hepatitis/enzymes/drug.html (5149 words)

	Atwell, McNaughton, Gorringe and Kaufman (1991) The effects of multiple anaerobic exercise periods on levels of ... (Site not responding. Last check: 2007-10-21)
		One hour prior to, immediately before, and immediately post-exercise, as well as one hour post exercise, blood samples were taken from the subjects after they had performed an exhaustive 60 s bout of exercise on a Repco Exertech, air braked cycle ergometer.
		Blood samples were analysed for blood lactate, creatine kinase (CK), aspartate transaminase (AST), and lactate dehydrogenase (LDH).
		It is felt that the measurement of a single enzyme to indicate muscle damage at this time is not warranted and that the collective measurement of enzymes LDH, CK and AST are a much better overall indicator of muscular damage at the cellular level.
	www.getcited.org /pub/103342796 (279 words)

	Common Liver Function Tests - Liver, Hepatic, Biliary Disorders Health Guide
		Serum Aminotransferases (transaminases) - This enzyme is released from damaged liver cells.
		Alanine Transaminase (ALT) Test - This enzyme is released from damaged liver cells.
		Aspartate Transaminase (AST) Test - This enzyme is released from damaged liver, heart, muscle, or brain cells.
	www.umm.edu /liver/tests.htm (332 words)

	Mouse protein: P05202 - Aspartate aminotransferase, mitochondrial precursor (EC ) (Transaminase A) (Glutamate ...
		Mouse protein: P05202 - Aspartate aminotransferase, mitochondrial precursor (EC) (Transaminase A) (Glutamate oxaloacetate transaminase 2).
		Aspartate aminotransferase, mitochondrial precursor (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 2).
		Structural organization of the mouse mitochondrial aspartate aminotransferase gene.
	marvester.embl.de /marvester/P052/P05202.htm (642 words)

	Microarray Probe Set Details Contig2799_at
		aspartate transaminase (EC 2.6.1.1) AAT3 precursor - proso millet Length = 428; 2.
		embCAA45022.1 0 aspartate aminotransferase [Panicum miliaceum] Length = 428; 3.
		For each experiment's statistic, upper row (red) is for MAS 5.0 and lower row (blue) is for RMA (log2) estimation.
	www.barleybase.org /barley1_probeset.php?probeset=Contig2799_at (251 words)

	OUTPUT from blastx for 50072-2-9-F05 (Site not responding. Last check: 2007-10-21)
		57 2e-07 pirD64385 aspartate transaminase (EC 2.6.1.1) - Methanoco...
		50 1e-05 pirT14611 alanine transaminase homolog - Trypanosoma cruz...
		50 1e-05 pirT14609 alanine transaminase homolog - Trypanosoma cruz...
	cbr-rbc.nrc-cnrc.gc.ca /reith/tetra/tetra5/50072-2-9-F05.html (466 words)

	The Body: Both Tenofovir and Stavudine Well Tolerated in HCV-Coinfected Patients
		Of the 600 antiretroviral-naive patients enrolled, HCV infection was found in 30/299 (10%) and 20/301 (7%) patients in the tenofovir and stavudine arms, respectively.
		At baseline, the mean alanine transaminase (ALT) level for these patients was 50 IU/L. At week 144, the ALT level had increased by 2.0 IU/L in the tenofovir group and 3.1 IU/L in the stavudine group, a non-significant difference.
		The aspartate transaminase (AST) levels were 0.3 IU/L and 5.7 IU/L for the tenofovir and stavudine arms, respectively, with a trend favoring tenofovir (P =.11).
	www.thebody.com /confs/aids2004/sax3.html (547 words)

	Adult Health Advisor 2005.2: Blood (Serum) Glutamic-Oxaloacetic Transaminase (SGOT) Test
		You should speak to your physician or make an appointment to be seen if you have questions or concerns about this information or your medical condition.
		Other names for this enzyme are aspartate aminotranskinase, aspartate transaminase, and AST.
		The SGOT level is measured to check the function of your liver, kidney, heart, pancreas, muscles, and red blood cells.
	www.med.umich.edu /1libr/aha/aha_sgot_crs.htm (506 words)

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