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| | Aspiration Pneumonia: Current Concepts and Approach to Management |
 | | Aspiration of pathogens from a previously colonized oropharynx is the primary pathway by which organisms gain entrance to the lungs, and therefore, in a broad sense, most pneumonias, are aspiration-related. |
 | | While pneumonia is part of the infectious aspiration syndrome, other infectious syndromes can result, including lung abscess, necrotizing pneumonia, and empyema. Because community-acquired aspiration pneumonia usually involves anaerobic bacteria, aspiration pneumonia should be viewed as part of a continuum that can progress to cavitation (lung abscess), or even empyema formation. |
 | | Antibiotic therapy for patients with aspiration pneumonia should be based on an assessment of severity of illness (severe or nonsevere infection; Table III), where the infection was acquired (community versus nosocomial), and the presence or absence of risk factors for gram-negative rod colonization. |
| www.medscape.com /content/1998/00/40/87/408725/408725.xml (2628 words) |
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